Published in Nat Commun on January 20, 2017
Genome editing. The new frontier of genome engineering with CRISPR-Cas9. Science (2014) 10.43
Construction of transgenic Drosophila by using the site-specific integrase from phage phiC31. Genetics (2004) 9.98
Retracted An enhanced transient expression system in plants based on suppression of gene silencing by the p19 protein of tomato bushy stunt virus. Plant J (2003) 9.35
Mitotic stability of yeast chromosomes: a colony color assay that measures nondisjunction and chromosome loss. Cell (1985) 8.78
Microsatellites: simple sequences with complex evolution. Nat Rev Genet (2004) 8.64
TALENs: a widely applicable technology for targeted genome editing. Nat Rev Mol Cell Biol (2012) 7.01
An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination. Nat Genet (1998) 5.95
A set of vectors with a tetracycline-regulatable promoter system for modulated gene expression in Saccharomyces cerevisiae. Yeast (1997) 5.95
GAL4 system in Drosophila: a fly geneticist's Swiss army knife. Genesis (2002) 5.40
Mutation rate in human microsatellites: influence of the structure and length of the tandem repeat. Am J Hum Genet (1998) 5.26
The effective mutation rate at Y chromosome short tandem repeats, with application to human population-divergence time. Am J Hum Genet (2003) 4.34
Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality. Nat Genet (1998) 3.89
A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods (2008) 3.79
Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain. Development (2004) 3.75
A ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stress. Cell (2012) 3.27
Specialized ribosome system: preferential translation of a single mRNA species by a subpopulation of mutated ribosomes in Escherichia coli. Proc Natl Acad Sci U S A (1987) 3.22
Germline and somatic transformation of mating Tetrahymena thermophila by particle bombardment. Genetics (1997) 3.04
A robust inducible-repressible promoter greatly facilitates gene knockouts, conditional expression, and overexpression of homologous and heterologous genes in Tetrahymena thermophila. Proc Natl Acad Sci U S A (2002) 2.46
A decade of systems biology. Annu Rev Cell Dev Biol (2010) 2.30
Nascent peptide-dependent translation arrest leads to Not4p-mediated protein degradation by the proteasome. J Biol Chem (2009) 2.25
A network of orthogonal ribosome x mRNA pairs. Nat Chem Biol (2005) 2.20
Cysteine-rich domain isoforms of the neuregulin-1 gene are required for maintenance of peripheral synapses. Neuron (2000) 2.11
Prions in yeast. Genetics (2012) 2.04
Dissecting the role of N-myc in development using a single targeting vector to generate a series of alleles. Curr Biol (1998) 2.02
Using translational enhancers to increase transgene expression in Drosophila. Proc Natl Acad Sci U S A (2012) 1.98
Evaluation of potential reference genes for reverse transcription-qPCR studies of physiological responses in Drosophila melanogaster. J Insect Physiol (2011) 1.91
One core, two shells: bacterial and eukaryotic ribosomes. Nat Struct Mol Biol (2012) 1.77
Receptor for activated C kinase 1 stimulates nascent polypeptide-dependent translation arrest. EMBO Rep (2010) 1.59
Chloramphenicol acetyltransferase. Annu Rev Biophys Biophys Chem (1991) 1.50
Genetic analysis of the Shine-Dalgarno interaction: selection of alternative functional mRNA-rRNA combinations. RNA (1996) 1.29
Tetrahymena thermophila. Curr Biol (2005) 1.25
Refined crystal structure of type III chloramphenicol acetyltransferase at 1.75 A resolution. J Mol Biol (1990) 1.23
Hydrophobin fusions for high-level transient protein expression and purification in Nicotiana benthamiana. Plant Physiol (2009) 1.17
Optimization of elastin-like polypeptide fusions for expression and purification of recombinant proteins in plants. Biotechnol Bioeng (2009) 1.15
Gene targeting methods for studying nuclear transport factors in mice. Methods (2006) 1.14
The structure of SAICAR synthase: an enzyme in the de novo pathway of purine nucleotide biosynthesis. Structure (1998) 1.12
Mutation rates of TGFBR2 and ACVR2 coding microsatellites in human cells with defective DNA mismatch repair. PLoS One (2008) 1.08
Fine-tuning gene networks using simple sequence repeats. Proc Natl Acad Sci U S A (2012) 1.07
Stepwise deletions of polyA sequences in mismatch repair-deficient colorectal cancers. Am J Pathol (2001) 1.04
Directing ribosomes to a single mRNA species: a method to study ribosomal RNA mutations and their effects on translation of a single messenger in Escherichia coli. Methods Enzymol (1987) 1.02
Ribosomes slide on lysine-encoding homopolymeric A stretches. Elife (2015) 0.96
A retrosynthetic biology approach to metabolic pathway design for therapeutic production. BMC Syst Biol (2011) 0.95
The conjugation-specific Die5 protein is required for development of the somatic nucleus in both Paramecium and Tetrahymena. Eukaryot Cell (2010) 0.94
Protein body formation in stable transgenic tobacco expressing elastin-like polypeptide and hydrophobin fusion proteins. BMC Biotechnol (2013) 0.91
Failure of RQC machinery causes protein aggregation and proteotoxic stress. Nature (2016) 0.89
The Rqc2/Tae2 subunit of the ribosome-associated quality control (RQC) complex marks ribosome-stalled nascent polypeptide chains for aggregation. Elife (2016) 0.89
Translational control by lysine-encoding A-rich sequences. Sci Adv (2015) 0.88
Zygotic expression of the double-stranded RNA binding motif protein Drb2p is required for DNA elimination in the ciliate Tetrahymena thermophila. Eukaryot Cell (2011) 0.87
A renaissance in RNA synthetic biology: new mechanisms, applications and tools for the future. Curr Opin Chem Biol (2015) 0.84
Transcription initiation from within P elements generates hypomorphic mutations in Drosophila melanogaster. Genetics (2011) 0.84
Engineering of Secondary Metabolism. Annu Rev Genet (2015) 0.83
The synthetic biology toolbox for tuning gene expression in yeast. FEMS Yeast Res (2015) 0.82
Predictable tuning of protein expression in bacteria. Nat Methods (2016) 0.81
Synthetic biology approaches to engineer T cells. Curr Opin Immunol (2015) 0.78
Synthetic biology platform technologies for antimicrobial applications. Adv Drug Deliv Rev (2016) 0.78
Relationship between promoter sequence and its strength in gene expression. Eur Phys J E Soft Matter (2014) 0.77
Single cell visualization of yeast gene expression shows correlation of epigenetic switching between multiple heterochromatic regions through multiple generations. PLoS Biol (2013) 0.77
Synthetic biology-application-oriented cell engineering. Curr Opin Biotechnol (2016) 0.76
Hypomorphic phenotype of Foxn1 gene-modified rats by CRISPR/Cas9 system. Transgenic Res (2016) 0.76