Published in Proc Natl Acad Sci U S A on December 01, 1978
Human plasma protein C: isolation, characterization, and mechanism of activation by alpha-thrombin. J Clin Invest (1979) 2.18
Purification of human C4b-binding protein and formation of its complex with vitamin K-dependent protein S. Biochem J (1983) 1.94
Comparison of amino acid sequence of bovine coagulation Factor IX (Christmas Factor) with that of other vitamin K-dependent plasma proteins. Proc Natl Acad Sci U S A (1979) 1.77
Cloning and sequencing of liver cDNA coding for bovine protein C. Proc Natl Acad Sci U S A (1984) 1.45
Vitamin K-dependent carboxylase: possible role of the substrate "propeptide" as an intracellular recognition site. Proc Natl Acad Sci U S A (1987) 0.82
Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
A protein sequenator. Eur J Biochem (1967) 17.03
EVIDENCE FOR NONIDENTICAL CHAINS IN THE BETA-GALACTOSIDASE OF ESCHERICHIA COLI K12. J Biol Chem (1965) 4.45
Reversible blocking of amino groups with citraconic anhydride. Biochem J (1968) 4.15
Application of sequenator analyses to the study of proteins. Biochemistry (1972) 3.88
A new vitamin K-dependent protein. Purification from bovine plasma and preliminary characterization. J Biol Chem (1976) 3.57
Anticoagulant properties of bovine plasma protein C following activation by thrombin. Biochemistry (1977) 2.96
Agarose gel electrophoresis. Scand J Clin Lab Invest Suppl (1972) 2.32
Proteolytic activation of protein C from bovine plasma. Biochemistry (1976) 2.12
A new vitamin K-dependent protein. A phospholipid-binding zymogen of a serine esterase. J Biol Chem (1976) 1.64
Modification of the single tryptophan residue of staphylococcal nuclease by a new mild oxidizing agent. J Biol Chem (1970) 1.51
Bovine factor X1 (Stuart factor). Primary structure of the light chain. Proc Natl Acad Sci U S A (1975) 1.31
Identification of functional arginine residues in ribonuclease A and lysozyme. J Biol Chem (1975) 1.27
Vitamin K and the biosynthesis of prothrombin. V. Gamma-carboxyglutamic acids, the vitamin K-dependent structures in prothrombin. J Biol Chem (1975) 1.22
Advances in the analysis of amino acid phenylthiohydantoins by high performance liquid chromatography. Anal Biochem (1976) 1.06
Identification of gamma-carboxyglutamic acid residues in bovine factors IX and X, and in a new vitamin K-dependent protein. FEBS Lett (1976) 0.92
An improved procedure for automated Edman degradation used for determination of the N-terminal amino acid sequence of human transcobalamin I and human intrinsic factor. Eur J Biochem (1976) 0.91
The nature of a hydroxylamine-sensitive bond in collagen. Biochem Biophys Res Commun (1969) 0.85
Blocked alpha-amino groups in peptides due to diketopiperazine formation. FEBS Lett (1974) 0.80
A new vitamin K-dependent protein. Purification from bovine plasma and preliminary characterization. J Biol Chem (1976) 3.57
Vitamin K dependent modifications of glutamic acid residues in prothrombin. Proc Natl Acad Sci U S A (1974) 3.24
Vitamin K-dependent formation of gamma-carboxyglutamic acid. Annu Rev Biochem (1977) 2.10
High molecular weight complex in human plasma between vitamin K-dependent protein S and complement component C4b-binding protein. Proc Natl Acad Sci U S A (1981) 1.83
Inactivation of human coagulation factor V by activated protein C. J Biol Chem (1983) 1.76
A new vitamin K-dependent protein. A phospholipid-binding zymogen of a serine esterase. J Biol Chem (1976) 1.64
Amino acid sequence of the heavy chain of bovine protein C. J Biol Chem (1982) 1.50
Measurement of antibodies against glutamic acid decarboxylase 65 (GADA): two new 125I assays compared with [35S]GAD 65-ligand binding assay. Clin Chem (1997) 1.48
Thrombin-catalyzed activation of human coagulation factor V. J Biol Chem (1982) 1.46
Beta-hydroxyaspartic acid in vitamin K-dependent proteins. J Biol Chem (1983) 1.45
Hyperproinsulinemia segregates young adult patients with newly diagnosed autoimmune (type 1) and non-autoimmune (type 2) diabetes. Scand J Clin Lab Invest (2005) 1.39
[How reliable is the laboratory? Increased needs of patient-related quality assurance]. Lakartidningen (1999) 1.38
Inhibitory effect of activated protein C on activation of prothrombin by platelet-bound factor Xa. Eur J Biochem (1980) 1.31
How an epidermal growth factor (EGF)-like domain binds calcium. High resolution NMR structure of the calcium form of the NH2-terminal EGF-like domain in coagulation factor X. J Biol Chem (1992) 1.27
beta-Hydroxyaspartic acid in vitamin K-dependent protein C. Proc Natl Acad Sci U S A (1983) 1.26
Primary structure of bovine vitamin K-dependent protein S. Proc Natl Acad Sci U S A (1986) 1.26
Isolation and sequence of the cDNA for human protein S, a regulator of blood coagulation. Proc Natl Acad Sci U S A (1986) 1.22
Vitamin K and the biosynthesis of prothrombin. V. Gamma-carboxyglutamic acids, the vitamin K-dependent structures in prothrombin. J Biol Chem (1975) 1.22
beta-Hydroxyasparagine in domains homologous to the epidermal growth factor precursor in vitamin K-dependent protein S. Proc Natl Acad Sci U S A (1987) 1.20
Structure of the Ca(2+)-free Gla domain sheds light on membrane binding of blood coagulation proteins. Nat Struct Biol (1995) 1.20
Vitamin K and the biosynthesis of prothrombin. 3. Structural comparison of an NH2-terminal fragment from normal and from dicoumarol-induced bovine prothrombin. J Biol Chem (1973) 1.19
Structure and function of protein C. Semin Thromb Hemost (1984) 1.17
Protein S, a new vitamin K-dependent protein from bovine plasma. FEBS Lett (1979) 1.14
Vitamin K and the biosynthesis of prothrombin. I. Identification and purification of a dicoumarol-induced abnormal prothrombin from bovine plasma. J Biol Chem (1972) 1.14
Amino acid sequence of the light chain of bovine protein C. J Biol Chem (1982) 1.12
Crustacean color-change hormone: amino acid sequence and chemical synthesis. Science (1972) 1.12
Binding of Ca 2+ to normal and dicoumarol-induced prothrombin. Biochem Biophys Res Commun (1973) 1.11
Calcium-binding properties of bovine factor X lacking the gamma-carboxyglutamic acid-containing region. J Biol Chem (1984) 1.11
Vitamin K and the biosynthesis of prothrombin. IV. Isolation of peptides containing prosthetic groups from normal prothrombin and the corresponding peptides from dicoumarol-induced prothrombin. J Biol Chem (1974) 1.11
Beta microseminoprotein is not a prostate-specific protein. Its identification in mucous glands and secretions. Am J Pathol (1990) 1.09
Protein C inhibitor in human body fluids. Seminal plasma is rich in inhibitor antigen deriving from cells throughout the male reproductive system. J Clin Invest (1992) 1.09
Radioimmunoassay of beta-microseminoprotein, a prostatic-secreted protein present in sera of both men and women. Clin Chem (1989) 1.06
Binding of bovine coagulation factor Xa to platelets. Biochemistry (1978) 1.04
The biosynthesis of rat alpha 1-antitrypsin. J Biol Chem (1982) 1.04
Calcium-dependent interaction between the epidermal growth factor precursor-like region of human protein C and a monoclonal antibody. J Biol Chem (1987) 1.02
Vitamin K and the biosynthesis of prothrombin. II. Structural comparison of normal and dicoumarol-induced bovine prothrombin. J Biol Chem (1972) 1.01
Localization of thrombin cleavage sites in the amino-terminal region of bovine protein S. J Biol Chem (1986) 1.00
Calcium binding of bovine protein S. Effect of thrombin cleavage and removal of the gamma-carboxyglutamic acid-containing region. J Biol Chem (1986) 0.99
A conotoxin from Conus textile with unusual posttranslational modifications reduces presynaptic Ca2+ influx. Proc Natl Acad Sci U S A (1999) 0.98
Calcium binding to the isolated beta-hydroxyaspartic acid-containing epidermal growth factor-like domain of bovine factor X. J Biol Chem (1989) 0.98
Dicumarol-induced prothrombin in bovine plasma. Acta Chem Scand (1970) 0.98
Structure of a light-adapting hormone from the shrimp, Pandalus borealis. Biochim Biophys Acta (1976) 0.97
Effects of Ca2+ binding on the protease module of factor Xa and its interaction with factor Va. Evidence for two Gla-independent Ca(2+)-binding sites in factor Xa. J Biol Chem (1993) 0.97
Beta-cell function in relation to islet cell antibodies during the first 3 yr after clinical diagnosis of diabetes in type II diabetic patients. Diabetes Care (1993) 0.97
Relationship between anticoagulant activities and polyanionic properties of rabbit thrombomodulin. J Biol Chem (1988) 0.97
Post-translational modifications in proteins involved in blood coagulation. J Thromb Haemost (2005) 0.96
Autonomic neuropathy in Type 2 diabetic patients is associated with hyperinsulinaemia and hypertriglyceridaemia. Diabet Med (1999) 0.96
erythro-beta-Hydroxyaspartic acid in bovine factor IX and factor X. FEBS Lett (1984) 0.94
High levels of antigen-specific islet antibodies predict future beta-cell failure in patients with onset of diabetes in adult age. J Clin Endocrinol Metab (2001) 0.94
Calcium binding to the epidermal growth factor homology region of bovine protein C. J Biol Chem (1988) 0.93
Thrombospondin is a slow tight-binding inhibitor of plasmin. Biochemistry (1992) 0.93
Effects of gamma-carboxyglutamic acid and epidermal growth factor-like modules of factor IX on factor X activation. Studies using proteolytic fragments of bovine factor IX. J Biol Chem (1992) 0.93
Translation and processing of normal (PiMM) and abnormal (PiZZ) human alpha 1-antitrypsin. FEBS Lett (1983) 0.92
Identification of gamma-carboxyglutamic acid residues in bovine factors IX and X, and in a new vitamin K-dependent protein. FEBS Lett (1976) 0.92
Characterization of the human sex hormone binding globulin (SHBG) gene and demonstration of two transcripts in both liver and testis. Nucleic Acids Res (1989) 0.92
The relative orientation of Gla and EGF domains in coagulation factor X is altered by Ca2+ binding to the first EGF domain. A combined NMR-small angle X-ray scattering study. Biochemistry (1996) 0.91
Intracranial meningioma--a population study of ten years. Acta Neurol Scand (1970) 0.91
Beta-hydroxyaspartic acid in the first epidermal growth factor-like domain of protein C. Its role in Ca2+ binding and biological activity. J Biol Chem (1988) 0.91
Calcium binding to tandem repeats of EGF-like modules. Expression and characterization of the EGF-like modules of human Notch-1 implicated in receptor-ligand interactions. Protein Sci (1997) 0.91
HLA-DQB1 genotypes, islet antibodies and beta cell function in the classification of recent-onset diabetes among young adults in the nationwide Diabetes Incidence Study in Sweden. Diabetologia (2006) 0.89
A cDNA coding for human sex hormone binding globulin. Homology to vitamin K-dependent protein S. FEBS Lett (1987) 0.88
Chromosome aberrations in tenosynovial giant cell tumors and nontumorous synovial tissue. Genes Chromosomes Cancer (1993) 0.88
EGF-like module pair 3-4 in vitamin K-dependent protein S: modulation of calcium affinity of module 4 by module 3, and interaction with factor X. J Mol Biol (1999) 0.87
Effect of Ca2+ on the structure of vitamin K-dependent coagulation factors. Haemostasis (1996) 0.87
1H NMR assignment and secondary structure of the Ca2(+)-free form of the amino-terminal epidermal growth factor like domain in coagulation factor X. Biochemistry (1990) 0.87
Structure determination of two conotoxins from Conus textile by a combination of matrix-assisted laser desorption/ionization time-of-flight and electrospray ionization mass spectrometry and biochemical methods. J Mass Spectrom (2000) 0.86
Modulation of fibrinolysis by thrombospondin. Ann N Y Acad Sci (1992) 0.86
Structure of the red-pigment-concentrating hormone of the shrimp, Pandalus borealis. Biochim Biophys Acta (1974) 0.85
Three-dimensional structure of the apo form of the N-terminal EGF-like module of blood coagulation factor X as determined by NMR spectroscopy and simulated folding. Biochemistry (1992) 0.85
The high affinity calcium-binding sites in the epidermal growth factor module region of vitamin K-dependent protein S. J Biol Chem (1997) 0.85
Islet cell antibody frequency differs from that of glutamic acid decarboxylase antibodies/IA2 antibodies after diagnosis of diabetes. Acta Paediatr (2000) 0.85
Gender, autoantibodies, and obesity in newly diagnosed diabetic patients aged 40-75 years. Diabetes Care (1998) 0.84
Identification and purification of vitamin K-dependent proteins and peptides with monoclonal antibodies specific for gamma -carboxyglutamyl (Gla) residues. J Biol Chem (2000) 0.84
Purification and characterization of two proteins with co-lipase activity from porcine pancreas. Biochim Biophys Acta (1973) 0.84
Population-based screening for prostate cancer by measuring free and total serum prostate-specific antigen in Sweden. BJU Int (2003) 0.84
Molecular analysis of the gene for vitamin K dependent protein S and its pseudogene. Cloning and partial gene organization. Biochemistry (1990) 0.84
A conserved motif within the vitamin K-dependent carboxylase gene is widely distributed across animal phyla. J Biol Chem (2000) 0.83
Lumbar nerve root compression by intraspinal synovial cysts. Report of 8 cases. Acta Orthop Scand (1999) 0.83
Vitamin K, prothrombin, and gamma-carboxyglutamic acid. Adv Enzymol Relat Areas Mol Biol (1978) 0.83
The effect of aspartate hydroxylation on calcium binding to epidermal growth factor-like modules in coagulation factors IX and X. J Biol Chem (1993) 0.83
The gamma-carboxyglutamic acid and epidermal growth factor-like domains of factor X. Effect of isolated domains on prothrombin activation and endothelial cell binding of factor X. J Biol Chem (1991) 0.82
SHBG region of the anticoagulant cofactor protein S: secondary structure prediction, circular dichroism spectroscopy, and analysis of naturally occurring mutations. Proteins (1997) 0.82
The activation of prothrombin by platelet-bound factor Xa. Eur J Biochem (1980) 0.82
Insulin autoantibodies are of less value compared with islet antibodies in the clinical diagnosis of autoimmune type 1 diabetes in children older than 3 yr of age. Pediatr Diabetes (2002) 0.82
Characterization of monoclonal antibodies against human protein C specific for the calcium ion-induced conformation or for the activation peptide region. FEBS Lett (1985) 0.82
Characterization of recombinant epidermal growth factor (EGF)-like modules from vitamin-K-dependent protein S expressed in Spodoptera cells--the cofactor activity depends on the N-terminal EGF module in human protein S. Eur J Biochem (1998) 0.82
Synthesis of gamma-carboxylated polypeptides by alpha-cells of the pancreatic islets. Biochem Biophys Res Commun (2001) 0.82
gamma-Carboxyglutamic acid in human urine. Clin Chim Acta (1976) 0.82
Islet autoantibodies in the prediction of diabetes in school children. Diabetes Res Clin Pract (2001) 0.81
Immunohistochemical and in situ hybridization studies of beta-microseminoprotein in the human gastric mucosa. Histochem J (1998) 0.81