Identification of a polyphosphoinositide-modulated domain in gelsolin which binds to the sides of actin filaments.

PubWeight™: 1.76‹?› | Rank: Top 3%

🔗 View Article (PMC 2115109)

Published in J Cell Biol on March 01, 1988

Authors

H L Yin1, K Iida, P A Janmey

Author Affiliations

1: Hematology-Oncology Unit, Massachusetts General Hospital, Harvard Medical School, Boston 02114.

Articles citing this

Identification of a region in segment 1 of gelsolin critical for actin binding. EMBO J (1990) 2.36

Gelsolin has three actin-binding sites. J Cell Biol (1988) 2.04

Expression of human plasma gelsolin in Escherichia coli and dissection of actin binding sites by segmental deletion mutagenesis. J Cell Biol (1989) 1.97

SAC1p is an integral membrane protein that influences the cellular requirement for phospholipid transfer protein function and inositol in yeast. J Cell Biol (1993) 1.91

Identification of critical functional and regulatory domains in gelsolin. J Cell Biol (1989) 1.88

Determination of the alpha-actinin-binding site on actin filaments by cryoelectron microscopy and image analysis. J Cell Biol (1994) 1.74

A protein kinase C isozyme is translocated to cytoskeletal elements on activation. Cell Regul (1990) 1.69

Association of gelsolin with actin filaments and cell membranes of macrophages and platelets. J Cell Biol (1989) 1.54

Sequence of human villin: a large duplicated domain homologous with other actin-severing proteins and a unique small carboxy-terminal domain related to villin specificity. J Cell Biol (1988) 1.49

A role for gelsolin in actuating epidermal growth factor receptor-mediated cell motility. J Cell Biol (1996) 1.45

Evidence for functional homology in the F-actin binding domains of gelsolin and alpha-actinin: implications for the requirements of severing and capping. J Cell Biol (1992) 1.44

Cortical filamentous actin disassembly and scinderin redistribution during chromaffin cell stimulation precede exocytosis, a phenomenon not exhibited by gelsolin. J Cell Biol (1991) 1.41

Acanthamoeba actin and profilin can be cross-linked between glutamic acid 364 of actin and lysine 115 of profilin. J Cell Biol (1989) 1.38

Formation of liquid crystalline phase of actin filament solutions and its dependence on filament length as studied by optical birefringence. Biophys J (1991) 1.27

Direct observation of actin filament severing by gelsolin and binding by gCap39 and CapZ. J Cell Biol (1991) 1.27

ACTIN BINDING PROTEIN 29 from Lilium pollen plays an important role in dynamic actin remodeling. Plant Cell (2007) 1.25

Effects of caerulein on the apical cytoskeleton of the pancreatic acinar cell. J Clin Invest (1990) 1.21

Association of Phosphatidylinositol Kinase, Phosphatidylinositol Monophosphate Kinase, and Diacylglycerol Kinase with the Cytoskeleton and F-Actin Fractions of Carrot (Daucus carota L.) Cells Grown in Suspension Culture : Response to Cell Wall-Degrading Enzymes. Plant Physiol (1992) 1.21

Osteoclast cytosolic calcium, regulated by voltage-gated calcium channels and extracellular calcium, controls podosome assembly and bone resorption. J Cell Biol (1990) 1.21

Gelsolin-related amyloidosis. Identification of the amyloid protein in Finnish hereditary amyloidosis as a fragment of variant gelsolin. J Clin Invest (1991) 1.18

Determination of the gelsolin binding site on F-actin: implications for severing and capping. Biophys J (1998) 1.15

Are the conserved sequences in segment 1 of gelsolin important for binding actin? J Cell Biol (1992) 1.12

Chromaffin cell scinderin, a novel calcium-dependent actin filament-severing protein. EMBO J (1990) 1.08

Domain structure in actin-binding proteins: expression and functional characterization of truncated severin. J Cell Biol (1991) 1.05

Gelsolin modulates phospholipase C activity in vivo through phospholipid binding. J Cell Biol (1997) 1.05

In vivo analysis of functional domains from villin and gelsolin. J Cell Biol (1992) 1.03

An actin-associated protein present in the microtubule organizing center and the growth cones of PC-12 cells. J Neurosci (1992) 1.02

Mutational analysis of human profilin I reveals a second PI(4,5)-P2 binding site neighbouring the poly(L-proline) binding site. BMC Biochem (2002) 1.02

S100A11 is required for efficient plasma membrane repair and survival of invasive cancer cells. Nat Commun (2014) 1.01

Actin dynamics in platelets. Int Rev Cytol (2002) 0.99

Gelsolin modulation in epithelial and stromal cells of mammary carcinoma. Am J Pathol (1989) 0.97

Refined structure of villin 14T and a detailed comparison with other actin-severing domains. Protein Sci (1997) 0.91

Changes in mobility of chromaffin granules in actin network with its assembly and Ca(2+)-dependent disassembly by gelsolin. Biophys J (1993) 0.86

Ca2+ and pH determine the interaction of chromaffin cell scinderin with phosphatidylserine and phosphatidylinositol 4,5,-biphosphate and its cellular distribution during nicotinic-receptor stimulation and protein kinase C activation. J Cell Biol (1992) 0.84

H-prune-nm23-H1 protein complex and correlation to pathways in cancer metastasis. J Bioenerg Biomembr (2006) 0.83

A gelsolin-related protein from lobster muscle: cloning, sequence analysis and expression. Biochem J (1995) 0.80

Alpha 1-antitrypsin therapy mitigated ischemic stroke damage in rats. J Stroke Cerebrovasc Dis (2014) 0.76

Characterization of proteins regulated by interleukin-4 in 3T3-L1 adipocytes. Springerplus (2015) 0.75

Gelsolin-Like Domain 3 Plays Vital Roles in Regulating the Activities of the Lily Villin/Gelsolin/Fragmin Superfamily. PLoS One (2015) 0.75

Articles cited by this

The regulation of rabbit skeletal muscle contraction. I. Biochemical studies of the interaction of the tropomyosin-troponin complex with actin and the proteolytic fragments of myosin. J Biol Chem (1971) 35.39

Fluorimetry study of N-(1-pyrenyl)iodoacetamide-labelled F-actin. Local structural change of actin protomer both on polymerization and on binding of heavy meromyosin. Eur J Biochem (1981) 5.72

Control of cytoplasmic actin gel-sol transformation by gelsolin, a calcium-dependent regulatory protein. Nature (1979) 5.48

Nonmuscle actin-binding proteins. Annu Rev Cell Biol (1985) 5.46

Modulation of gelsolin function by phosphatidylinositol 4,5-bisphosphate. Nature (1987) 3.99

Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain. Nature (1986) 3.50

Ca2+ control of actin gelation. Interaction of gelsolin with actin filaments and regulation of actin gelation. J Biol Chem (1980) 2.73

Interactions of gelsolin and gelsolin-actin complexes with actin. Effects of calcium on actin nucleation, filament severing, and end blocking. Biochemistry (1985) 2.16

Polyphosphoinositide micelles and polyphosphoinositide-containing vesicles dissociate endogenous gelsolin-actin complexes and promote actin assembly from the fast-growing end of actin filaments blocked by gelsolin. J Biol Chem (1987) 2.08

Structure and mobility of actin filaments as measured by quasielastic light scattering, viscometry, and electron microscopy. J Biol Chem (1986) 1.99

Reversible binding of actin to gelsolin and profilin in human platelet extracts. J Cell Biol (1987) 1.97

The actin filament-severing domain of plasma gelsolin. J Cell Biol (1986) 1.93

Actin-gelsolin interactions. Evidence for two actin-binding sites. J Biol Chem (1984) 1.81

Interaction of plasma gelsolin with G-actin and F-actin in the presence and absence of calcium ions. J Biol Chem (1985) 1.73

F-Actin-depolymerizing activity of human serum. Eur J Biochem (1979) 1.71

Kinetic analysis of F-actin depolymerization in the presence of platelet gelsolin and gelsolin-actin complexes. J Cell Biol (1985) 1.66

Genomic organization and biosynthesis of secreted and cytoplasmic forms of gelsolin. J Cell Biol (1988) 1.49

Platelet activation induces the formation of a stable gelsolin-actin complex from monomeric gelsolin. J Biol Chem (1984) 1.47

Definition of an N-terminal actin-binding domain and a C-terminal Ca2+ regulatory domain in human brevin. J Cell Biol (1986) 1.46

Isolation and properties of two actin-binding domains in gelsolin. J Biol Chem (1985) 1.41

An actin-destabilizing factor is present in human plasma. Experientia (1979) 1.41

Reversibility of gelsolin/actin interaction in macrophages. Evidence of Ca2+-dependent and Ca2+-independent pathways. J Exp Med (1987) 1.35

Actin polymerization. The effect of brevin on filament size and rate of polymerization. J Biol Chem (1984) 1.27

Characterization of brevin, a serum protein that shortens actin filaments. Proc Natl Acad Sci U S A (1981) 1.25

Sequential binding of actin monomers to plasma gelsolin and its inhibition by vitamin D-binding protein. Biochem Biophys Res Commun (1986) 1.17

Interactions of pig plasma gelsolin with G-actin. Eur J Biochem (1986) 1.13

Immuno-identification of Ca2+-induced conformational changes in human gelsolin and brevin. J Cell Biol (1986) 1.11

Kinetics of actin monomer exchange at the slow growing ends of actin filaments and their relation to the elongation of filaments shortened by gelsolin. J Muscle Res Cell Motil (1986) 1.09

Plasma-gelsolin-binding sites on the actin sequence. Eur J Biochem (1987) 1.04

Binding of pig plasma gelsolin to F-actin and partial fractionation into calcium-dependent and calcium-independent forms. Eur J Biochem (1986) 1.02

Actin filament disassembly in blood plasma. FEBS Lett (1980) 1.01

Covalent complexes formed between plasma gelsolin and actin with a zero-length cross-linking compound. Biochemistry (1985) 0.94

Characterization of the Ca2+-induced conformational changes in gelsolin and identification of interaction regions between actin and gelsolin. Biochemistry (1986) 0.91

Fluorescent study of tobacco mosaic virus protein. Biochim Biophys Acta (1977) 0.91

Articles by these authors

Identification of the C3bi receptor of human monocytes and macrophages by using monoclonal antibodies. Proc Natl Acad Sci U S A (1983) 8.57

Nonmuscle actin-binding proteins. Annu Rev Cell Biol (1985) 5.46

Complement receptor (CR1) deficiency in erythrocytes from patients with systemic lupus erythematosus. J Exp Med (1982) 4.96

Actin-binding protein requirement for cortical stability and efficient locomotion. Science (1992) 4.66

Thrombin receptor ligation and activated Rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets. Cell (1995) 4.39

Modulation of gelsolin function by phosphatidylinositol 4,5-bisphosphate. Nature (1987) 3.99

Preparation and evaluation of a compressed tablet rapidly disintegrating in the oral cavity. Chem Pharm Bull (Tokyo) (1996) 3.97

Complement receptor is an inhibitor of the complement cascade. J Exp Med (1981) 3.65

MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium-calmodulin. Nature (1992) 3.49

Unique role of the complement receptor CR1 in the degradation of C3b associated with immune complexes. J Exp Med (1982) 3.42

Cofilin is an essential component of the yeast cortical cytoskeleton. J Cell Biol (1993) 3.23

Electron microscopic studies on mode of action of polymyxin. J Bacteriol (1969) 2.97

Corequirement of specific phosphoinositides and small GTP-binding protein Cdc42 in inducing actin assembly in Xenopus egg extracts. J Cell Biol (1998) 2.90

Cofilin is a component of intranuclear and cytoplasmic actin rods induced in cultured cells. Proc Natl Acad Sci U S A (1987) 2.70

The polyelectrolyte nature of F-actin and the mechanism of actin bundle formation. J Biol Chem (1996) 2.65

Phosphorylation of Ser-3 of cofilin regulates its essential function on actin. Genes Cells (1996) 2.52

Signaling pathways and cell mechanics involved in wound closure by epithelial cell sheets. Curr Biol (2000) 2.52

Development of a simple and highly sensitive enzyme immunoassay for hepatitis C virus core antigen. J Clin Microbiol (1999) 2.41

Inhibition of the interactions of cofilin, destrin, and deoxyribonuclease I with actin by phosphoinositides. J Biol Chem (1990) 2.35

Identification of the membrane receptor for the complement fragment C3d by means of a monoclonal antibody. J Exp Med (1983) 2.31

Polymorphism of human erythrocyte C3b/C4b receptor. Proc Natl Acad Sci U S A (1983) 2.30

Interactions of gelsolin and gelsolin-actin complexes with actin. Effects of calcium on actin nucleation, filament severing, and end blocking. Biochemistry (1985) 2.16

Polyphosphoinositide micelles and polyphosphoinositide-containing vesicles dissociate endogenous gelsolin-actin complexes and promote actin assembly from the fast-growing end of actin filaments blocked by gelsolin. J Biol Chem (1987) 2.08

The COOH terminus of the c-Abl tyrosine kinase contains distinct F- and G-actin binding domains with bundling activity. J Cell Biol (1994) 2.07

Release of the antimicrobial peptide LL-37 from DNA/F-actin bundles in cystic fibrosis sputum. Eur Respir J (2007) 2.06

Structure and mobility of actin filaments as measured by quasielastic light scattering, viscometry, and electron microscopy. J Biol Chem (1986) 1.99

Reversible binding of actin to gelsolin and profilin in human platelet extracts. J Cell Biol (1987) 1.97

F-actin, a model polymer for semiflexible chains in dilute, semidilute, and liquid crystalline solutions. Biophys J (1996) 1.96

Identification of a polyphosphoinositide-binding sequence in an actin monomer-binding domain of gelsolin. J Biol Chem (1992) 1.95

Thymosin beta 15: a novel regulator of tumor cell motility upregulated in metastatic prostate cancer. Nat Med (1996) 1.94

Two mammalian heat shock proteins, HSP90 and HSP100, are actin-binding proteins. Proc Natl Acad Sci U S A (1986) 1.93

The actin filament-severing domain of plasma gelsolin. J Cell Biol (1986) 1.93

Dental pulp cells for induced pluripotent stem cell banking. J Dent Res (2010) 1.92

The role of actin-binding protein 280 in integrin-dependent mechanoprotection. J Biol Chem (1998) 1.89

Identification of critical functional and regulatory domains in gelsolin. J Cell Biol (1989) 1.88

Quantitative analysis of cytomegalovirus load using a real-time PCR assay. J Med Virol (2000) 1.84

Cell wall alterations of gram-negative bacteria by aminoglycoside antibiotics. Antimicrob Agents Chemother (1974) 1.81

Bidirectional translocation of neurofilaments along microtubules mediated in part by dynein/dynactin. Mol Biol Cell (2000) 1.56

The mechanism of action of decay-accelerating factor (DAF). DAF inhibits the assembly of C3 convertases by dissociating C2a and Bb. J Exp Med (1987) 1.55

Occurrence of caldesmon (a calmodulin-binding protein) in cultured cells: comparison of normal and transformed cells. Proc Natl Acad Sci U S A (1984) 1.53

Hepatitis B virus X protein is a transcriptional modulator that communicates with transcription factor IIB and the RNA polymerase II subunit 5. J Biol Chem (1997) 1.52

Conformational states of fibronectin. Effects of pH, ionic strength, and collagen binding. J Biol Chem (1982) 1.52

Mechanical properties of actin filament networks depend on preparation, polymerization conditions, and storage of actin monomers. Biophys J (1998) 1.51

Clinical characteristics of febrile convulsions during primary HHV-6 infection. Arch Dis Child (2000) 1.50

Inhibition of cell division of Escherichia coli by a new synthetic penicillin, piperacillin. Antimicrob Agents Chemother (1978) 1.44

Structure of the profilin-poly-L-proline complex involved in morphogenesis and cytoskeletal regulation. Nat Struct Biol (1997) 1.44

Structural heterogeneity of the C3b/C4b receptor (Cr 1) on human peripheral blood cells. J Exp Med (1983) 1.43

Effect of polymyxin on the bacteriophage receptors of the cell walls of gram-negative bacteria. J Bacteriol (1971) 1.43

Elevated levels of pro-inflammatory cytokines in coronary artery thrombi. Int J Cardiol (1999) 1.43

Destrin, a mammalian actin-depolymerizing protein, is closely related to cofilin. Cloning and expression of porcine brain destrin cDNA. J Biol Chem (1990) 1.42

Isolation and properties of two actin-binding domains in gelsolin. J Biol Chem (1985) 1.41

Mechanisms of mitochondria-neurofilament interactions. J Neurosci (2003) 1.41

Interactions of tensin with actin and identification of its three distinct actin-binding domains. J Cell Biol (1994) 1.40

Reduction in viscosity of cystic fibrosis sputum in vitro by gelsolin. Science (1994) 1.38

Pulmonary thromboembolic hypertension in systemic lupus erythematosus with lupus anticoagulant: histopathological analysis of localization and distribution of thromboemboli in pulmonary vasculature. Intern Med (1995) 1.38

Cooperativity in F-actin: binding of gelsolin at the barbed end affects structure and dynamics of the whole filament. J Mol Biol (1996) 1.37

Mechanical effects of neurofilament cross-bridges. Modulation by phosphorylation, lipids, and interactions with F-actin. J Biol Chem (1996) 1.37

Cell permeant polyphosphoinositide-binding peptides that block cell motility and actin assembly. J Biol Chem (2001) 1.35

Partial deletion of the cloned rfb gene of Escherichia coli O9 results in synthesis of a new O-antigenic lipopolysaccharide. J Bacteriol (1989) 1.34

Higher concentrations of matrix metalloproteinases in bronchoalveolar lavage fluid of patients with adult respiratory distress syndrome. Am J Respir Crit Care Med (1997) 1.33

Role of plasma gelsolin and the vitamin D-binding protein in clearing actin from the circulation. J Clin Invest (1986) 1.30

Distribution of actin filament lengths measured by fluorescence microscopy. Am J Physiol (1992) 1.28

Inhibition of actin polymerization by a synthetic dodecapeptide patterned on the sequence around the actin-binding site of cofilin. J Biol Chem (1991) 1.28

Hierarchical self-assembly of F-actin and cationic lipid complexes: stacked three-layer tubule networks. Science (2000) 1.28

Polyproline affinity method for purification of platelet profilin and modification with pyrene-maleimide. Methods Enzymol (1991) 1.27

Opposite effects of electrostatics and steric exclusion on bundle formation by F-actin and other filamentous polyelectrolytes. Biochemistry (1997) 1.26

KRAS or BRAF mutation status is a useful predictor of sensitivity to MEK inhibition in ovarian cancer. Br J Cancer (2008) 1.24

Long term effect of erythromycin therapy in patients with chronic Pseudomonas aeruginosa infection. Thorax (1995) 1.24

Reaction mechanisms of beta1H globulin. Int Arch Allergy Appl Immunol (1978) 1.24

Modulation of gelsolin function. Activation at low pH overrides Ca2+ requirement. J Biol Chem (1993) 1.23

Domain analysis of cortexillin I: actin-bundling, PIP(2)-binding and the rescue of cytokinesis. EMBO J (1999) 1.23

Leptin induces mitogen-activated protein kinase-dependent proliferation of C3H10T1/2 cells. J Biol Chem (1997) 1.22

A simple indentation device for measuring micrometer-scale tissue stiffness. J Phys Condens Matter (2010) 1.22

Profilin, a weak CAP for actin and RAS. Cell (1991) 1.21

Genomic imprinting of human p57KIP2 and its reduced expression in Wilms' tumors. Hum Mol Genet (1996) 1.21

Cofilin and gelsolin segment-1: molecular dynamics simulation and biochemical analysis predict a similar actin binding mode. J Mol Biol (1998) 1.20

Characterization of dental pulp stem cells of human tooth germs. J Dent Res (2008) 1.19

D3 phosphoinositides and outside-in integrin signaling by glycoprotein IIb-IIIa mediate platelet actin assembly and filopodial extension induced by phorbol 12-myristate 13-acetate. J Biol Chem (1996) 1.19

Sequential binding of actin monomers to plasma gelsolin and its inhibition by vitamin D-binding protein. Biochem Biophys Res Commun (1986) 1.17

Depression of gelsolin levels and detection of gelsolin-actin complexes in plasma of patients with acute lung injury. Am Rev Respir Dis (1988) 1.15

Quantitative measurement of plasma gelsolin and its incorporation into fibrin clots. J Lab Clin Med (1987) 1.14

Direct action of gonadotropin-releasing hormone (LH-RH) analogue on ovary: an alternative acting mechanism of buserelin. Arch Gynecol Obstet (1991) 1.14

Detection of hepatitis C core antigen in the antibody negative 'window' phase of hepatitis C infection. Vox Sang (2000) 1.14

Expression of 9 Salmonella typhimurium enzymes for cobinamide synthesis. Identification of the 11-methyl and 20-methyl transferases of corrin biosynthesis. FEBS Lett (1992) 1.12

Distinct biochemical characteristics of the two human profilin isoforms. Eur J Biochem (1995) 1.12

Complement fixing abilities of IgA myeloma proteins and their fragments: the activation of complement through the classical pathway. Immunochemistry (1976) 1.11

Gelsolin displaces phalloidin from actin filaments. A new fluorescence method shows that both Ca2+ and Mg2+ affect the rate at which gelsolin severs F-actin. J Biol Chem (1994) 1.11

The reconstruction of progressive facial hemi-atrophy by free vascularised dermis-fat flaps. Br J Plast Surg (1981) 1.11

The structure of divalent cation-induced aggregates of PIP2 and their alteration by gelsolin and tau. Biophys J (1997) 1.10

Phalloidin binding and rheological differences among actin isoforms. Biochemistry (1996) 1.10

Kinetics of actin monomer exchange at the slow growing ends of actin filaments and their relation to the elongation of filaments shortened by gelsolin. J Muscle Res Cell Motil (1986) 1.09

Selective production of transgenic mice using green fluorescent protein as a marker. Nat Biotechnol (1997) 1.09

Evidence that a 27-residue sequence is the actin-binding site of ABP-120. J Biol Chem (1991) 1.09

Mechanical perturbation elicits a phenotypic difference between Dictyostelium wild-type cells and cytoskeletal mutants. Biophys J (1996) 1.08

Reversible induction of actin rods in mouse C3H-2K cells by incubation in salt buffers and by treatment with non-ionic detergents. Exp Cell Res (1986) 1.08

The plasma and cytoplasmic forms of human gelsolin differ in disulfide structure. Biochemistry (1996) 1.08

The actin side-binding domain of gelsolin also caps actin filaments. Implications for actin filament severing. J Biol Chem (1994) 1.08

Functional properties of membrane-associated complement receptor CR1. J Immunol (1983) 1.08

A new method for the preparation of EAC14 cell with human or guinea-pig serum. J Immunol Methods (1974) 1.07