Reversible binding of actin to gelsolin and profilin in human platelet extracts.

PubWeight™: 1.97‹?› | Rank: Top 2%

🔗 View Article (PMC 2114783)

Published in J Cell Biol on August 01, 1987

Authors

S E Lind, P A Janmey, C Chaponnier, T J Herbert, T P Stossel

Articles citing this

Purification of profilin from Saccharomyces cerevisiae and analysis of profilin-deficient cells. J Cell Biol (1990) 3.42

Mechanisms of actin rearrangements mediating platelet activation. J Cell Biol (1992) 3.28

Mechanism of the interaction of human platelet profilin with actin. J Cell Biol (1991) 2.15

The cytoskeleton of the resting human blood platelet: structure of the membrane skeleton and its attachment to actin filaments. J Cell Biol (1991) 2.11

Identification of critical functional and regulatory domains in gelsolin. J Cell Biol (1989) 1.88

Coordinated regulation of platelet actin filament barbed ends by gelsolin and capping protein. J Cell Biol (1996) 1.85

Identification of a polyphosphoinositide-modulated domain in gelsolin which binds to the sides of actin filaments. J Cell Biol (1988) 1.76

Phosphoinositides and phosphoinositide-utilizing enzymes in detergent-insoluble lipid domains. Mol Biol Cell (1996) 1.60

Association of gelsolin with actin filaments and cell membranes of macrophages and platelets. J Cell Biol (1989) 1.54

The affinities of human platelet and Acanthamoeba profilin isoforms for polyphosphoinositides account for their relative abilities to inhibit phospholipase C. Cell Regul (1990) 1.52

Isolation of a 5-kilodalton actin-sequestering peptide from human blood platelets. Proc Natl Acad Sci U S A (1990) 1.47

Effects of profilin and profilactin on actin structure and function in living cells. J Cell Biol (1992) 1.39

Actin filament barbed-end capping activity in neutrophil lysates: the role of capping protein-beta 2. Mol Biol Cell (1995) 1.38

Profilins constitute a novel family of functional plant pan-allergens. J Exp Med (1992) 1.35

Thymosin beta 4 sequesters the majority of G-actin in resting human polymorphonuclear leukocytes. J Cell Biol (1992) 1.33

Association of profilin with filament-free regions of human leukocyte and platelet membranes and reversible membrane binding during platelet activation. J Cell Biol (1989) 1.32

Identification of actin nucleation activity and polymerization inhibitor in ameboid cells: their regulation by chemotactic stimulation. J Cell Biol (1989) 1.31

Thymosin beta 4 (Fx peptide) is a potent regulator of actin polymerization in living cells. Proc Natl Acad Sci U S A (1992) 1.29

Gelsolin-actin interaction and actin polymerization in human neutrophils. J Cell Biol (1990) 1.26

Regulation of the formation of osteoclastic actin rings by proline-rich tyrosine kinase 2 interacting with gelsolin. J Cell Biol (2003) 1.24

Importance of free actin filament barbed ends for Arp2/3 complex function in platelets and fibroblasts. Proc Natl Acad Sci U S A (2002) 1.23

Exogenous nucleation sites fail to induce detectable polymerization of actin in living cells. J Cell Biol (1990) 1.22

The actin released from profilin--actin complexes is insufficient to account for the increase in F-actin in chemoattractant-stimulated polymorphonuclear leukocytes. J Cell Biol (1990) 1.16

Disruption of microfilament organization in living nonmuscle cells by microinjection of plasma vitamin D-binding protein or DNase I. Proc Natl Acad Sci U S A (1990) 1.11

Gelsolin modulates phospholipase C activity in vivo through phospholipid binding. J Cell Biol (1997) 1.05

Activation of protein kinase C in rat basophilic leukemia cells stimulates increased production of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate: correlation with actin polymerization. Mol Biol Cell (1995) 1.04

Changes in phosphatidylinositol metabolism in response to hyperosmotic stress in Daucus carota L. cells grown in suspension culture. Plant Physiol (1993) 1.04

Gelsolin and ADF/cofilin enhance the actin dynamics of motile cells. Proc Natl Acad Sci U S A (2000) 1.03

VASP protects actin filaments from gelsolin: an in vitro study with implications for platelet actin reorganizations. Cell Motil Cytoskeleton (2000) 1.02

Actin polymerization in differentiated vascular smooth muscle cells requires vasodilator-stimulated phosphoprotein. Am J Physiol Cell Physiol (2009) 1.01

Ca2+ regulation of gelsolin activity: binding and severing of F-actin. Biophys J (1998) 1.00

Lack of correlation between changes in polyphosphoinositide levels and actin/gelsolin complexes in A431 cells treated with epidermal growth factor. J Cell Biol (1991) 1.00

Actin dynamics in platelets. Int Rev Cytol (2002) 0.99

Gelsolin modulation in epithelial and stromal cells of mammary carcinoma. Am J Pathol (1989) 0.97

Regulation of the antigen-induced F-actin response in rat basophilic leukemia cells by protein kinase C. J Cell Biol (1991) 0.96

Localization of calcium and microfilament changes in mechanically stressed cells. Cell Biophys (1990) 0.93

Circulating actin-gelsolin complexes following oleic acid-induced lung injury. Am J Pathol (1988) 0.92

Identification of the functional profilin gene, its localization to chromosome subband 17p13.3, and demonstration of its deletion in some patients with Miller-Dieker syndrome. Am J Hum Genet (1990) 0.90

Studies on the actin-binding protein HS1 in platelets. BMC Cell Biol (2007) 0.89

Platelet membrane skeleton revealed by quick-freeze deep-etch. Anat Rec (1990) 0.89

Proteins regulating actin assembly in oogenesis and early embryogenesis of Xenopus laevis: gelsolin is the major cytoplasmic actin-binding protein. J Cell Biol (1988) 0.88

Formation and contraction of a microfilamentous shell in saponin-permeabilized platelets. J Cell Biol (1991) 0.81

Role of gelsolin interaction with actin in regulation and creation of actin nuclei in chemotactic peptide activated polymorphonuclear neutrophils. Mol Biol Cell (1992) 0.75

Articles cited by this

Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91

Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A (1979) 365.71

The regulation of rabbit skeletal muscle contraction. I. Biochemical studies of the interaction of the tropomyosin-troponin complex with actin and the proteolytic fragments of myosin. J Biol Chem (1971) 35.39

High resolution two-dimensional electrophoresis of basic as well as acidic proteins. Cell (1977) 30.04

Actin and actin-binding proteins. A critical evaluation of mechanisms and functions. Annu Rev Biochem (1986) 9.17

Nonmuscle actin-binding proteins. Annu Rev Cell Biol (1985) 5.46

Structural interaction of cytoskeletal components. J Cell Biol (1981) 5.19

Specific interaction between phosphatidylinositol 4,5-bisphosphate and profilactin. Nature (1985) 4.60

Modulation of gelsolin function by phosphatidylinositol 4,5-bisphosphate. Nature (1987) 3.99

Quantitative analysis of the effect of Acanthamoeba profilin on actin filament nucleation and elongation. Biochemistry (1984) 3.15

Cytochalasin D inhibits actin polymerization and induces depolymerization of actin filaments formed during platelet shape change. Nature (1981) 2.63

Cytoplasmic free Ca2+ in human platelets: Ca2+ thresholds and Ca-independent activation for shape-change and secretion. FEBS Lett (1982) 2.60

Interactions of gelsolin and gelsolin-actin complexes with actin. Effects of calcium on actin nucleation, filament severing, and end blocking. Biochemistry (1985) 2.16

Structure of macrophage actin-binding protein molecules in solution and interacting with actin filaments. J Mol Biol (1981) 2.04

Poly(L-proline)-binding proteins from chick embryos are a profilin and a profilactin. Eur J Biochem (1985) 2.01

The actin filament-severing domain of plasma gelsolin. J Cell Biol (1986) 1.93

Purification and characterization of actophorin, a new 15,000-dalton actin-binding protein from Acanthamoeba castellanii. J Biol Chem (1986) 1.83

Actin-gelsolin interactions. Evidence for two actin-binding sites. J Biol Chem (1984) 1.81

Interaction of plasma gelsolin with G-actin and F-actin in the presence and absence of calcium ions. J Biol Chem (1985) 1.73

Kinetic analysis of F-actin depolymerization in the presence of platelet gelsolin and gelsolin-actin complexes. J Cell Biol (1985) 1.66

An actin-depolymerizing protein (depactin) from starfish oocytes: properties and interaction with actin. J Cell Biol (1983) 1.62

Purification and characterization of a gelsolin-actin complex from human platelets. Evidence for Ca2+-insensitive functions. J Biol Chem (1983) 1.58

Changes in the cytoskeletal structure of human platelets following thrombin activation. J Biol Chem (1981) 1.58

Platelet activation induces the formation of a stable gelsolin-actin complex from monomeric gelsolin. J Biol Chem (1984) 1.47

Characterization of platelet extracts before and after stimulation with respect to the possible role of profilactin as microfilament precursor. Cell (1981) 1.45

Effect of Acanthamoeba profilin on the pre-steady state kinetics of actin polymerization and on the concentration of F-actin at steady state. J Biol Chem (1983) 1.43

Different calcium dependence of the capping and cutting activities of villin. J Biol Chem (1986) 1.41

Human platelets contain profilin, a potential regulator of actin polymerisability. FEBS Lett (1978) 1.39

The amino acid sequence of profilin from calf spleen. FEBS Lett (1979) 1.39

Mechanism of action of Acanthamoeba profilin: demonstration of actin species specificity and regulation by micromolar concentrations of MgCl2. J Cell Biol (1982) 1.37

Reversibility of gelsolin/actin interaction in macrophages. Evidence of Ca2+-dependent and Ca2+-independent pathways. J Exp Med (1987) 1.35

Platelet actin: sub-cellular distribution and association with profilin. FEBS Lett (1978) 1.34

Diacylglycerol in large alpha-actinin/actin complexes and in the cytoskeleton of activated platelets. Nature (1985) 1.29

Actin filament content and organization in unstimulated platelets. J Cell Biol (1984) 1.28

Platelet activation and microfilament bundling. J Cell Biol (1981) 1.21

Effects of macrophage profilin on actin in the presence and absence of acumentin and gelsolin. J Biol Chem (1985) 1.20

Polymerization and organization of actin filaments within platelets. Semin Hematol (1983) 1.16

Kinetics of actin monomer exchange at the slow growing ends of actin filaments and their relation to the elongation of filaments shortened by gelsolin. J Muscle Res Cell Motil (1986) 1.09

Human platelets contain gelsolin. A regulator of actin filament length. J Clin Invest (1982) 1.07

Calcium dependence of villin-induced actin depolymerization. Biochemistry (1984) 1.05

Nucleation of actin polymerization from profilactin. Opposite effects of different nuclei. Biochim Biophys Acta (1982) 0.95

A 90 000-dalton actin-binding protein from platelets. Comparison with villin and plasma brevin. Biochim Biophys Acta (1982) 0.94

Dissociation of Ca2+ mobilization from breakdown of phosphatidylinositol 4,5-bisphosphate in activated human platelets. J Biochem (1986) 0.83

Articles by these authors

Control of cytoplasmic actin gel-sol transformation by gelsolin, a calcium-dependent regulatory protein. Nature (1979) 5.48

Nonmuscle actin-binding proteins. Annu Rev Cell Biol (1985) 5.46

Actin-binding protein requirement for cortical stability and efficient locomotion. Science (1992) 4.66

Thrombin receptor ligation and activated Rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets. Cell (1995) 4.39

Alpha-smooth muscle actin expression upregulates fibroblast contractile activity. Mol Biol Cell (2001) 4.25

Modulation of gelsolin function by phosphatidylinositol 4,5-bisphosphate. Nature (1987) 3.99

Interactions of actin, myosin, and a new actin-binding protein of rabbit pulmonary macrophages. II. Role in cytoplasmic movement and phagocytosis. J Cell Biol (1976) 3.84

Human endothelial actin-binding protein (ABP-280, nonmuscle filamin): a molecular leaf spring. J Cell Biol (1990) 3.76

Phagocytosis: recognition and ingestion. Semin Hematol (1975) 3.63

Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain. Nature (1986) 3.50

MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium-calmodulin. Nature (1992) 3.49

Isolation and properties of actin, myosin, and a new actinbinding protein in rabbit alveolar macrophages. J Biol Chem (1975) 3.41

Isolation and properties of phagocytic vesicles from polymorphonuclear leukocytes. J Clin Invest (1971) 3.39

Cofilin is an essential component of the yeast cortical cytoskeleton. J Cell Biol (1993) 3.23

Quantitative studies of phagocytosis. Kinetic effects of cations and heat-labile opsonin. J Cell Biol (1973) 3.14

Hemostatic, inflammatory, and fibroblast responses are blunted in mice lacking gelsolin. Cell (1995) 3.08

Mechanical tension controls granulation tissue contractile activity and myofibroblast differentiation. Am J Pathol (2001) 3.07

Vascular smooth muscle cells differ from other smooth muscle cells: predominance of vimentin filaments and a specific alpha-type actin. Proc Natl Acad Sci U S A (1981) 2.94

Corequirement of specific phosphoinositides and small GTP-binding protein Cdc42 in inducing actin assembly in Xenopus egg extracts. J Cell Biol (1998) 2.90

Interactions between actin, myosin, and an actin-binding protein from rabbit alveolar macrophages. Alveolar macrophage myosin Mg-2+-adenosine triphosphatase requires a cofactor for activation by actin. J Biol Chem (1975) 2.88

Quantitative studies of phagocytosis by polymorphonuclear leukocytes: use of emulsions to measure the initial rate of phagocytosis. J Clin Invest (1972) 2.88

The small GTPase RalA targets filamin to induce filopodia. Proc Natl Acad Sci U S A (1999) 2.87

Cytochalasin B and the structure of actin gels. J Mol Biol (1979) 2.81

Prestressed F-actin networks cross-linked by hinged filamins replicate mechanical properties of cells. Proc Natl Acad Sci U S A (2006) 2.80

Endocytic protein intersectin-l regulates actin assembly via Cdc42 and N-WASP. Nat Cell Biol (2001) 2.75

Ca2+ control of actin gelation. Interaction of gelsolin with actin filaments and regulation of actin gelation. J Biol Chem (1980) 2.73

The polyelectrolyte nature of F-actin and the mechanism of actin bundle formation. J Biol Chem (1996) 2.65

Resemblance of actin-binding protein/actin gels to covalently crosslinked networks. Nature (1990) 2.58

Myosin in polymorphonuclear leukocytes. J Biol Chem (1973) 2.55

Contractile proteins in leukocyte function. Semin Hematol (1983) 2.55

Signaling pathways and cell mechanics involved in wound closure by epithelial cell sheets. Curr Biol (2000) 2.52

Management of the fractured scaphoid using a new bone screw. J Bone Joint Surg Br (1984) 2.51

The opsonic fragment of the third component of human complement (C3). J Exp Med (1975) 2.51

Herbert screw fixation of scaphoid fractures. J Bone Joint Surg Br (1996) 2.50

Distribution of actin-binding protein and myosin in macrophages during spreading and phagocytosis. J Cell Biol (1980) 2.45

Interactions of actin, myosin, and an actin-binding protein of rabbit pulmonary macrophages. III. Effects of cytochalasin B. J Cell Biol (1976) 2.42

Phagocytosis (third of three parts). N Engl J Med (1974) 2.41

Translational and rotational diffusion constants of tobacco mosaic virus from Rayleigh linewidths. Biophys J (1969) 2.38

Neutrophil action dysfunction and abnormal neutrophil behavior. N Engl J Med (1974) 2.35

An inherited abnormality of neutrophil adhesion. Its genetic transmission and its association with a missing protein. N Engl J Med (1980) 2.32

Filamin A, the Arp2/3 complex, and the morphology and function of cortical actin filaments in human melanoma cells. J Cell Biol (2001) 2.29

Myeloperoxidase-mediated iodination by granulocytes. Intracellular site of operation and some regulating factors. J Clin Invest (1974) 2.28

The gelation of actin by actin-binding protein. J Biol Chem (1978) 2.27

Enhanced motility in NIH 3T3 fibroblasts that overexpress gelsolin. Science (1991) 2.26

Serum-dependent phagocytosis of paraffin oil emulsified with bacterial lipopolysaccharide. J Exp Med (1973) 2.25

Evaluation of opsonic and leukocyte function with a spectrophotometric test in patients with infection and with phagocytic disorders. Blood (1973) 2.25

Gelsolin is a downstream effector of rac for fibroblast motility. EMBO J (1998) 2.23

The mechanical properties of actin gels. Elastic modulus and filament motions. J Biol Chem (1994) 2.23

Mechanical strain in actin networks regulates FilGAP and integrin binding to filamin A. Nature (2011) 2.22

Actin-binding protein promotes the bipolar and perpendicular branching of actin filaments. J Cell Biol (1980) 2.22

Interactions of gelsolin and gelsolin-actin complexes with actin. Effects of calcium on actin nucleation, filament severing, and end blocking. Biochemistry (1985) 2.16

Actin and tubulin co-cap with surface immunoglobulins in mouse B lymphocytes. Nature (1977) 2.10

Polyphosphoinositide micelles and polyphosphoinositide-containing vesicles dissociate endogenous gelsolin-actin complexes and promote actin assembly from the fast-growing end of actin filaments blocked by gelsolin. J Biol Chem (1987) 2.08

Ca2+ control of actin filament length. Effects of macrophage gelsolin on actin polymerization. J Biol Chem (1981) 2.07

The COOH terminus of the c-Abl tyrosine kinase contains distinct F- and G-actin binding domains with bundling activity. J Cell Biol (1994) 2.07

Purification and structural properties of gelsolin, a Ca2+-activated regulatory protein of macrophages. J Biol Chem (1980) 2.06

Release of the antimicrobial peptide LL-37 from DNA/F-actin bundles in cystic fibrosis sputum. Eur Respir J (2007) 2.06

Structure of macrophage actin-binding protein molecules in solution and interacting with actin filaments. J Mol Biol (1981) 2.04

Distribution of actin-binding protein and myosin in polymorphonuclear leukocytes during locomotion and phagocytosis. Cell (1981) 2.03

Prevention of degradation of human polymorphonuclear leukocyte proteins by diisopropylfluorophosphate. Blood (1980) 2.01

Structure and mobility of actin filaments as measured by quasielastic light scattering, viscometry, and electron microscopy. J Biol Chem (1986) 1.99

Regulation of glycogen metabolism in polymorphonuclear leukocytes. J Biol Chem (1970) 1.98

F-actin, a model polymer for semiflexible chains in dilute, semidilute, and liquid crystalline solutions. Biophys J (1996) 1.96

Phagocytosis in chronic granulomatous disease and the Chediak-Higashi syndrome. N Engl J Med (1972) 1.96

Identification of a polyphosphoinositide-binding sequence in an actin monomer-binding domain of gelsolin. J Biol Chem (1992) 1.95

Thymosin beta 15: a novel regulator of tumor cell motility upregulated in metastatic prostate cancer. Nat Med (1996) 1.94

The actin filament-severing domain of plasma gelsolin. J Cell Biol (1986) 1.93

Phagocytes as carcinogens: malignant transformation produced by human neutrophils. Science (1985) 1.90

The role of actin-binding protein 280 in integrin-dependent mechanoprotection. J Biol Chem (1998) 1.89

Identification of critical functional and regulatory domains in gelsolin. J Cell Biol (1989) 1.88

Lipids of alveolar macrophages, polymorphonuclear leukocytes, and their phagocytic vesicles. J Clin Invest (1972) 1.84

A neutrophil disorder induced by capnocytophaga, a dental micro-organism. N Engl J Med (1979) 1.84

Isolation and properties of phagocytic vesicles. II. Alveolar macrophages. J Clin Invest (1972) 1.82

Phagocytosis (first of three parts). N Engl J Med (1974) 1.81

Lipid peroxidation by human blood phagocytes. J Clin Invest (1974) 1.79

Identification of a polyphosphoinositide-modulated domain in gelsolin which binds to the sides of actin filaments. J Cell Biol (1988) 1.76

Gelsolin-polyphosphoinositide interaction. Full expression of gelsolin-inhibiting function by polyphosphoinositides in vesicular form and inactivation by dilution, aggregation, or masking of the inositol head group. J Biol Chem (1989) 1.76

Focal adhesion features during myofibroblastic differentiation are controlled by intracellular and extracellular factors. J Cell Sci (2001) 1.75

Volume: papers and academic promotion. Ann Intern Med (1987) 1.74

Reversible oxidant-induced increases in albumin transfer across cultured endothelium: alterations in cell shape and calcium homeostasis. Blood (1985) 1.71

Mutation caused by human phagocytes. Science (1981) 1.67

American oncology and the discourse on hope. Cult Med Psychiatry (1990) 1.63

Stimulated human phagocytes produce cytogenetic changes in cultured mammalian cells. N Engl J Med (1983) 1.62

Isolation and some properties of macrophage alpha-actinin: evidence that it is not an actin gelling protein. Biochemistry (1984) 1.61

The motor of amoeboid leucocytes. Biochem Soc Symp (1980) 1.61

Stress-dependent elasticity of composite actin networks as a model for cell behavior. Phys Rev Lett (2006) 1.61

The Rac1- and RhoG-specific GEF domain of Trio targets filamin to remodel cytoskeletal actin. Nat Cell Biol (2000) 1.61