T Cell Receptor and Cytokine Signaling Can Function at Different Stages to Establish and Maintain Transcriptional Memory and Enable T Helper Cell Differentiation.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 28316598)

Published in Front Immunol on March 03, 2017

Authors

Sarah L Bevington1, Pierre Cauchy1, David R Withers2, Peter J L Lane2, Peter N Cockerill1

Author Affiliations

1: Institute of Cancer and Genomic Sciences, Institute of Biomedical Research, University of Birmingham , Birmingham , UK.
2: Institute of Immunology and Immunotherapy, Institute of Biomedical Research, University of Birmingham , Birmingham , UK.

Articles cited by this

(truncated to the top 100)

High-resolution profiling of histone methylations in the human genome. Cell (2007) 85.74

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature (1999) 34.47

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol (1989) 31.72

The role of chromatin during transcription. Cell (2007) 26.48

Mapping and analysis of chromatin state dynamics in nine human cell types. Nature (2011) 24.37

Central memory and effector memory T cell subsets: function, generation, and maintenance. Annu Rev Immunol (2004) 17.54

The complex language of chromatin regulation during transcription. Nature (2007) 16.97

Active genes are tri-methylated at K4 of histone H3. Nature (2002) 15.68

Nuclease hypersensitive sites in chromatin. Annu Rev Biochem (1988) 13.48

Differentiation of effector CD4 T cell populations (*). Annu Rev Immunol (2010) 11.80

The biology of chromatin remodeling complexes. Annu Rev Biochem (2009) 10.02

Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells. Immunity (2009) 9.73

Effector and memory T-cell differentiation: implications for vaccine development. Nat Rev Immunol (2002) 9.45

Functions of site-specific histone acetylation and deacetylation. Annu Rev Biochem (2007) 7.49

Homeostasis of naive and memory T cells. Immunity (2008) 7.48

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position. Nat Methods (2013) 7.06

Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation. Immunity (1998) 5.38

Co-stimulatory members of the TNFR family: keys to effective T-cell immunity? Nat Rev Immunol (2003) 5.01

Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling. Cell (1998) 4.95

A validated regulatory network for Th17 cell specification. Cell (2012) 4.82

Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells. Nat Immunol (2003) 3.82

Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA. Nature (1998) 3.71

T cell memory. Annu Rev Immunol (2001) 3.70

Opposing signals from the Bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells. Immunity (2011) 3.58

Latent enhancers activated by stimulation in differentiated cells. Cell (2013) 3.44

Early Th1 cell differentiation is marked by a Tfh cell-like transition. Immunity (2011) 3.24

A comparative encyclopedia of DNA elements in the mouse genome. Nature (2014) 3.22

Dynamic exchange at regulatory elements during chromatin remodeling underlies assisted loading mechanism. Cell (2011) 3.00

Regulation of the Th2 cytokine locus by a locus control region. Immunity (2003) 2.84

Naive and effector CD4 T cells differ in their requirements for T cell receptor versus costimulatory signals. J Immunol (1996) 2.76

Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation. Immunity (2010) 2.70

Crosstalk among Histone Modifications. Cell (2008) 2.70

Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types. Immunity (2011) 2.53

STATs shape the active enhancer landscape of T cell populations. Cell (2012) 2.45

Hypersensitive site 7 of the TH2 locus control region is essential for expressing TH2 cytokine genes and for long-range intrachromosomal interactions. Nat Immunol (2004) 2.44

Herpesvirus entry mediator, a member of the tumor necrosis factor receptor (TNFR) family, interacts with members of the TNFR-associated factor family and activates the transcription factors NF-kappaB and AP-1. J Biol Chem (1997) 2.33

Qualitative changes accompany memory T cell generation: faster, more effective responses at lower doses of antigen. J Immunol (2000) 2.23

Regulation of IL-4 gene expression by distal regulatory elements and GATA-3 at the chromatin level. Immunity (2001) 2.15

Genome-wide analysis of histone methylation reveals chromatin state-based regulation of gene transcription and function of memory CD8+ T cells. Immunity (2009) 2.11

Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development. Nat Immunol (2009) 2.05

The granulocyte-macrophage colony-stimulating factor/interleukin 3 locus is regulated by an inducible cyclosporin A-sensitive enhancer. Proc Natl Acad Sci U S A (1993) 2.01

Th2-specific chromatin remodeling and enhancer activity in the Th2 cytokine locus control region. Immunity (2004) 1.98

Early signaling events that underlie fate decisions of naive CD4(+) T cells toward distinct T-helper cell subsets. Immunol Rev (2013) 1.89

Epigenetic remodeling of the IL-2 and IFN-gamma loci in memory CD8 T cells is influenced by CD4 T cells. J Immunol (2006) 1.88

Resting memory CD8+ T cells are hyperreactive to antigenic challenge in vitro. J Exp Med (1996) 1.83

The methylcytosine dioxygenase Tet2 promotes DNA demethylation and activation of cytokine gene expression in T cells. Immunity (2015) 1.79

From naive to memory T cells. Immunol Rev (1996) 1.76

Tissue-specific mitotic bookmarking by hematopoietic transcription factor GATA1. Cell (2012) 1.74

CD4(+)CD3(-) accessory cells costimulate primed CD4 T cells through OX40 and CD30 at sites where T cells collaborate with B cells. Immunity (2003) 1.73

Human granulocyte-macrophage colony-stimulating factor enhancer function is associated with cooperative interactions between AP-1 and NFATp/c. Mol Cell Biol (1995) 1.66

CD27, a member of the tumor necrosis factor receptor superfamily, activates NF-kappaB and stress-activated protein kinase/c-Jun N-terminal kinase via TRAF2, TRAF5, and NF-kappaB-inducing kinase. J Biol Chem (1998) 1.64

Crucial role of MLL for the maintenance of memory T helper type 2 cell responses. Immunity (2006) 1.62

Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2. Nat Immunol (2011) 1.59

Rapid demethylation of the IFN-gamma gene occurs in memory but not naive CD8 T cells. J Immunol (2006) 1.58

Mice deficient in OX40 and CD30 signals lack memory antibody responses because of deficient CD4 T cell memory. J Immunol (2005) 1.52

CD8+ memory T cells (CD44high, Ly-6C+) are more sensitive than naive cells to (CD44low, Ly-6C-) to TCR/CD8 signaling in response to antigen. J Immunol (1998) 1.50

Structure and function of active chromatin and DNase I hypersensitive sites. FEBS J (2011) 1.49

Histone acetylation facilitates rapid and robust memory CD8 T cell response through differential expression of effector molecules (eomesodermin and its targets: perforin and granzyme B). J Immunol (2008) 1.44

The molecular basis of the memory T cell response: differential gene expression and its epigenetic regulation. Nat Rev Immunol (2012) 1.41

T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements. Nat Commun (2012) 1.39

ATP-dependent chromatin remodeling enzymes: two heads are not better, just different. Curr Opin Genet Dev (2008) 1.33

TCR signal transduction in antigen-specific memory CD8 T cells. J Immunol (2003) 1.33

T-cell memory differentiation: insights from transcriptional signatures and epigenetics. Immunology (2013) 1.29

A conserved role for human Nup98 in altering chromatin structure and promoting epigenetic transcriptional memory. PLoS Biol (2013) 1.27

RANTES production by memory phenotype T cells is controlled by a posttranscriptional, TCR-dependent process. Immunity (2002) 1.26

Granulocyte-macrophage colony-stimulating factor enhancer activation requires cooperation between NFAT and AP-1 elements and is associated with extensive nucleosome reorganization. Mol Cell Biol (2004) 1.21

STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells. J Exp Med (2010) 1.18

High-throughput functional testing of ENCODE segmentation predictions. Genome Res (2014) 1.17

Cutting edge: chromatin remodeling as a molecular basis for the enhanced functionality of memory CD8 T cells. J Immunol (2008) 1.16

Distinct epigenetic signatures delineate transcriptional programs during virus-specific CD8(+) T cell differentiation. Immunity (2014) 1.14

Inherited human OX40 deficiency underlying classic Kaposi sarcoma of childhood. J Exp Med (2013) 1.14

Cutting edge: stable epigenetic inheritance of regional IFN-gamma promoter demethylation in CD44highCD8+ T lymphocytes. J Immunol (1999) 1.13

A modular enhancer is differentially regulated by GATA and NFAT elements that direct different tissue-specific patterns of nucleosome positioning and inducible chromatin remodeling. Mol Cell Biol (2007) 1.07

Interleukin (IL)-4-independent maintenance of histone modification of the IL-4 gene loci in memory Th2 cells. J Biol Chem (2004) 1.06

A biochemical signature for rapid recall of memory CD4 T cells. J Immunol (2007) 1.06

Transcriptional regulation of mouse granulocyte-macrophage colony-stimulating factor/IL-3 locus. J Immunol (1995) 1.05

Hit-and-run transcriptional control by bZIP1 mediates rapid nutrient signaling in Arabidopsis. Proc Natl Acad Sci U S A (2014) 1.00

In vivo immunogold labeling confirms large-scale chromatin folding motifs. Nat Methods (2008) 1.00

Critical role of the Polycomb and Trithorax complexes in the maintenance of CD4 T cell memory. Semin Immunol (2009) 1.00

Critical synergy of CD30 and OX40 signals in CD4 T cell homeostasis and Th1 immunity to Salmonella. J Immunol (2008) 0.99

The role of STAT5 in lymphocyte development and transformation. Curr Opin Immunol (2012) 0.98

A conserved insulator that recruits CTCF and cohesin exists between the closely related but divergently regulated interleukin-3 and granulocyte-macrophage colony-stimulating factor genes. Mol Cell Biol (2009) 0.98

Making memories that last a lifetime: heritable functions of self-renewing memory CD8 T cells. Int Immunol (2010) 0.97

The human IL-3 locus is regulated cooperatively by two NFAT-dependent enhancers that have distinct tissue-specific activities. J Immunol (2002) 0.94

Developmental Acquisition of Regulomes Underlies Innate Lymphoid Cell Functionality. Cell (2016) 0.93

Regulation of memory T cells by γc cytokines. Cytokine (2009) 0.93

Bhlhe40 controls cytokine production by T cells and is essential for pathogenicity in autoimmune neuroinflammation. Nat Commun (2014) 0.93

The contribution of epigenetic memory to immunologic memory. Curr Opin Genet Dev (2011) 0.92

Histone acetylation at the single-cell level: a marker of memory CD8+ T cell differentiation and functionality. J Immunol (2010) 0.91

Inducible chromatin priming is associated with the establishment of immunological memory in T cells. EMBO J (2016) 0.87

Formation of a large, complex domain of histone hyperacetylation at human 14q32.1 requires the serpin locus control region. Nucleic Acids Res (2005) 0.87

Defining CD4 T cell memory by the epigenetic landscape of CpG DNA methylation. J Immunol (2015) 0.87

The human IL-3/granulocyte-macrophage colony-stimulating factor locus is epigenetically silent in immature thymocytes and is progressively activated during T cell development. J Immunol (2010) 0.87

Lineage relationship of CD8(+) T cell subsets is revealed by progressive changes in the epigenetic landscape. Cell Mol Immunol (2015) 0.85

A hit-and-run heat shock factor governs sustained histone methylation and transcriptional stress memory. EMBO J (2015) 0.85

Coordinated changes in DNA methylation in antigen-specific memory CD4 T cells. J Immunol (2013) 0.85

Genome-wide regulatory analysis reveals that T-bet controls Th17 lineage differentiation through direct suppression of IRF4. J Immunol (2013) 0.85

Runx1 binds as a dimeric complex to overlapping Runx1 sites within a palindromic element in the human GM-CSF enhancer. Nucleic Acids Res (2010) 0.85

The interface between transcriptional and epigenetic control of effector and memory CD8⁺ T-cell differentiation. Immunol Rev (2014) 0.82

T-cell identity and epigenetic memory. Curr Top Microbiol Immunol (2012) 0.82