Published in Front Immunol on March 03, 2017
Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells. J Immunol (2010) 9.72
FOXP3 controls regulatory T cell function through cooperation with NFAT. Cell (2006) 9.24
Epigenetic control of the foxp3 locus in regulatory T cells. PLoS Biol (2007) 7.86
Natural and adaptive foxp3+ regulatory T cells: more of the same or a division of labor? Immunity (2009) 6.11
Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production. Int Immunol (2007) 5.45
A phase III study of belatacept-based immunosuppression regimens versus cyclosporine in renal transplant recipients (BENEFIT study). Am J Transplant (2010) 5.40
Belatacept and Long-Term Outcomes in Kidney Transplantation. N Engl J Med (2016) 5.31
Costimulation blockade with belatacept in renal transplantation. N Engl J Med (2005) 4.86
Blockade of CTLA-4 on CD4+CD25+ regulatory T cells abrogates their function in vivo. J Immunol (2006) 3.42
Rejection of the kidney allograft. N Engl J Med (2010) 3.30
Prevention of acute and chronic allograft rejection with CD4+CD25+Foxp3+ regulatory T lymphocytes. Nat Med (2007) 3.22
Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis. Int Immunol (2006) 2.93
Quantitative DNA methylation analysis of FOXP3 as a new method for counting regulatory T cells in peripheral blood and solid tissue. Cancer Res (2009) 2.75
Helios expression is a marker of T cell activation and proliferation. PLoS One (2011) 2.55
The role of T-cell costimulatory activation pathways in transplant rejection. N Engl J Med (1998) 2.10
CD28 costimulation is essential for human T regulatory expansion and function. J Immunol (2008) 1.86
Hydrogen Sulfide Promotes Tet1- and Tet2-Mediated Foxp3 Demethylation to Drive Regulatory T Cell Differentiation and Maintain Immune Homeostasis. Immunity (2015) 1.62
tTregs, pTregs, and iTregs: similarities and differences. Immunol Rev (2014) 1.55
Cell-surface IL-7 receptor expression facilitates the purification of FOXP3(+) regulatory T cells. Trends Immunol (2006) 1.50
Active demethylation of the Foxp3 locus leads to the generation of stable regulatory T cells within the thymus. J Immunol (2013) 1.45
Molecular mechanisms of treg-mediated T cell suppression. Front Immunol (2012) 1.41
Oligodeoxynucleotides stabilize Helios-expressing Foxp3+ human T regulatory cells during in vitro expansion. Blood (2012) 1.36
The effect of costimulatory and interleukin 2 receptor blockade on regulatory T cells in renal transplantation. Am J Transplant (2008) 1.33
CTLA-4 is required by CD4+CD25+ Treg to control CD4+ T-cell lymphopenia-induced proliferation. Eur J Immunol (2009) 1.15
Regulatory T cells inhibit acute IFN-γ synthesis without blocking T-helper cell type 1 (Th1) differentiation via a compartmentalized requirement for IL-10. Proc Natl Acad Sci U S A (2011) 1.09
Immunosuppressive drugs and Tregs: a critical evaluation! Clin J Am Soc Nephrol (2009) 1.08
Differing effects of rapamycin or calcineurin inhibitor on T-regulatory cells in pediatric liver and kidney transplant recipients. Am J Transplant (2012) 1.06
Allorecognition pathways in transplant rejection and tolerance. Transplantation (2013) 1.02
Belatacept for kidney transplant recipients. Cochrane Database Syst Rev (2014) 0.99
Human regulatory T cells rapidly suppress T cell receptor-induced Ca(2+), NF-κB, and NFAT signaling in conventional T cells. Sci Signal (2011) 0.98
Interleukin-2 and STAT5 in regulatory T cell development and function. JAKSTAT (2013) 0.98
Helios Enhances Treg Cell Function in Cooperation With FoxP3. Arthritis Rheumatol (2015) 0.97
Signals and pathways controlling regulatory T cells. Immunol Rev (2014) 0.95
Absence of CD4CD25 regulatory T cell expansion in renal transplanted patients treated in vivo with Belatacept mediated CD28-CD80/86 blockade. Transpl Immunol (2007) 0.95
CD28 signaling in T regulatory precursors requires p56lck and rafts integrity to stabilize the Foxp3 message. J Immunol (2009) 0.93
Post-translational modification networks regulating FOXP3 function. Trends Immunol (2014) 0.92
Costimulatory blockade with mTor inhibition abrogates effector T-cell responses allowing regulatory T-cell survival in renal transplantation. Transpl Int (2011) 0.92
Regulatory T cell identity: formation and maintenance. Trends Immunol (2015) 0.91
Kidney transplant recipients treated with belatacept exhibit increased naïve and transitional B cells. Am J Transplant (2014) 0.88
High levels of IDO-expressing CD16+ peripheral cells, and Tregs in graft biopsies from kidney transplant recipients under belatacept treatment. Transplant Proc (2010) 0.87
Forkhead transcription factor FOXP3 upregulates CD25 expression through cooperation with RelA/NF-κB. PLoS One (2012) 0.84
T-cell phenotype in protocol renal biopsy from transplant recipients treated with belatacept-mediated co-stimulatory blockade. Nephrol Dial Transplant (2010) 0.83
Down-regulation of Tet2 prevents TSDR demethylation in IL2 deficient regulatory T cells. Biochem Biophys Res Commun (2014) 0.83
Effect of biologic agents on regulatory T cells. Transplant Rev (Orlando) (2011) 0.82
Decreased frequency of peripheral CD4(+) CD161(+) Th(17) -precursor cells in kidney transplant recipients on long-term therapy with Belatacept. Transpl Int (2012) 0.81
Belatacept and Tregs: friends or foes? Immunotherapy (2012) 0.78
Immunophenotyping of peripheral immunoregulatory as well as Th17A and Th22 cell subpopulations in kidney transplant recipients under belatacept or cyclosporine treatment. Transpl Immunol (2014) 0.76
Pediatric renal transplantation. Int J Organ Transplant Med (2012) 0.76