Published in EMBO J on January 01, 1988
Erythromycin resistance by ribosome modification. Antimicrob Agents Chemother (1995) 9.40
Streptococcus pneumoniae and Streptococcus pyogenes resistant to macrolides but sensitive to clindamycin: a common resistance pattern mediated by an efflux system. Antimicrob Agents Chemother (1996) 8.65
Mutations in 23S rRNA and ribosomal protein L4 account for resistance in pneumococcal strains selected in vitro by macrolide passage. Antimicrob Agents Chemother (2000) 4.31
Macrolide resistance conferred by base substitutions in 23S rRNA. Antimicrob Agents Chemother (2001) 4.17
Identification of mutations in 23S rRNA gene of clarithromycin-resistant Mycobacterium intracellulare. Antimicrob Agents Chemother (1994) 3.28
Macrolide resistance in Helicobacter pylori: rapid detection of point mutations and assays of macrolide binding to ribosomes. Antimicrob Agents Chemother (1997) 3.27
Transition mutations in the 23S rRNA of erythromycin-resistant isolates of Mycoplasma pneumoniae. Antimicrob Agents Chemother (1995) 3.22
Two new mechanisms of macrolide resistance in clinical strains of Streptococcus pneumoniae from Eastern Europe and North America. Antimicrob Agents Chemother (2000) 3.00
Genetic basis for clarithromycin resistance among isolates of Mycobacterium chelonae and Mycobacterium abscessus. Antimicrob Agents Chemother (1996) 2.92
Antibiotic resistance mutations in the chloroplast 16S and 23S rRNA genes of Chlamydomonas reinhardtii: correlation of genetic and physical maps of the chloroplast genome. Genetics (1989) 2.41
Genetic alterations in streptomycin-resistant Mycobacterium tuberculosis: mapping of mutations conferring resistance. Antimicrob Agents Chemother (1994) 2.23
Alterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin. BMC Biol (2004) 1.68
Macrolide resistance in Campylobacter jejuni and Campylobacter coli: molecular mechanism and stability of the resistance phenotype. Antimicrob Agents Chemother (2005) 1.64
Clinical resistance to erythromycin and clindamycin in cutaneous propionibacteria isolated from acne patients is associated with mutations in 23S rRNA. Antimicrob Agents Chemother (1997) 1.63
Evidence that some Frankia sp. strains are able to cross boundaries between Alnus and Elaeagnus host specificity groups. Appl Environ Microbiol (1992) 1.26
Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae. Antimicrob Agents Chemother (2004) 1.10
Cloning of a lincosamide resistance determinant from Streptomyces caelestis, the producer of celesticetin, and characterization of the resistance mechanism. J Bacteriol (1990) 1.05
Spontaneous erythromycin resistance mutation in a 23S rRNA gene, rrlA, of the extreme thermophile Thermus thermophilus IB-21. J Bacteriol (2001) 0.90
Molecular characterization of resistance to macrolides in Bartonella henselae. Antimicrob Agents Chemother (2006) 0.82
Characterization of Streptomyces venezuelae ATCC 10595 rRNA gene clusters and cloning of rrnA. J Bacteriol (1996) 0.75
DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A (1977) 790.54
Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. Gene (1985) 213.67
Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I. J Mol Biol (1977) 205.11
Studies on transformation of Escherichia coli with plasmids. J Mol Biol (1983) 116.81
Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. Gene (1977) 114.87
The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers. Gene (1982) 102.30
A complementation analysis of the restriction and modification of DNA in Escherichia coli. J Mol Biol (1969) 71.21
Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing. J Mol Biol (1980) 61.16
A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments. Gene (1982) 59.01
Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination. Proc Natl Acad Sci U S A (1983) 54.64
A system for shotgun DNA sequencing. Nucleic Acids Res (1981) 52.99
A small cosmid for efficient cloning of large DNA fragments. Gene (1980) 22.61
Structure of ribosomal RNA. Annu Rev Biochem (1984) 9.44
Import of proteins into mitochondria: precursor forms of the extramitochondrially made F1-ATPase subunits in yeast. Proc Natl Acad Sci U S A (1979) 5.21
Plasmids, recombination and chromosome mapping in Streptomyces lividans 66. J Gen Microbiol (1983) 5.06
Antibiotic resistance mutations in 16S and 23S ribosomal RNA genes of Escherichia coli. Nucleic Acids Res (1984) 3.94
Erythromycin-inducible resistance in Staphylococcus aureus: requirements for induction. J Bacteriol (1971) 3.93
Site of action of a ribosomal RNA methylase responsible for resistance to erythromycin and other antibiotics. J Biol Chem (1983) 3.11
Cloning of antibiotic resistance and nutritional genes in streptomycetes. J Bacteriol (1982) 3.06
Physical analysis of antibiotic-resistance genes from Streptomyces and their use in vector construction. Gene (1982) 2.81
A cobalt-containing medium for sporulation of Streptomyces species. J Bacteriol (1952) 2.64
Biochemical and genetic studies on two different types of erythromycin resistant mutants of Escherichia coli with altered ribosomal proteins. Mol Gen Genet (1973) 2.59
The Streptomyces plasmid SCP2*: its functional analysis and development into useful cloning vectors. Gene (1985) 2.46
Identification of two erythromycin resistance mutations in the mitochondrial gene coding for the large ribosomal RNA in yeast. Nucleic Acids Res (1982) 2.35
Chloramphenicol-erythromycin resistance mutations in a 23S rRNA gene of Escherichia coli. J Bacteriol (1985) 2.31
Methylation of 16S ribosomal RNA and resistance to aminoglycoside antibiotics in clones of Streptomyces lividans carrying DNA from Streptomyces tenjimariensis. Mol Gen Genet (1985) 1.77
Erythromycin resistance due to a mutation in a ribosomal RNA operon of Escherichia coli. Proc Natl Acad Sci U S A (1982) 1.73
Biochemical characterization of resistance determinants cloned from antibiotic-producing streptomycetes. J Bacteriol (1982) 1.70
23S ribosomal ribonucleic acid of macrolide-producing streptomycetes contains methylated adenine. J Bacteriol (1979) 1.52
The effect of delta-aminolevulinate on catalase T-messenger RNA levels in delta-aminolevulinate synthase-defective mutants of Saccharomyces cerevisiae. J Biol Chem (1980) 1.50
A family of r-determinants in Streptomyces spp. that specifies inducible resistance to macrolide, lincosamide, and streptogramin type B antibiotics. J Bacteriol (1981) 1.48
Integrated DNA sequences in three streptomycetes form related autonomous plasmids after transfer to Streptomyces lividans. Plasmid (1984) 1.34
Cloning and expression of a tylosin resistance gene from a tylosin-producing strain of Streptomyces fradiae. Mol Gen Genet (1986) 1.24
The mode of action of nosiheptide (multhiomycin) and the mechanism of resistance in the producing organism. J Gen Microbiol (1981) 0.87
Structure of the spiramycins (foromacidines) and their relationship with the leucomycins and carbomycins (magnamycins). J Am Chem Soc (1969) 0.79
Mechanism of inhibition of protein synthesis by spiramycin. Biochim Biophys Acta (1968) 0.79
The phytopathogenic bacteria Erwinia carotovora infects Drosophila and activates an immune response. Proc Natl Acad Sci U S A (2000) 2.86
Organization and nucleotide sequence analysis of a ribosomal RNA gene cluster from Streptomyces ambofaciens. Gene (1989) 1.93
The integrated conjugative plasmid pSAM2 of Streptomyces ambofaciens is related to temperate bacteriophages. EMBO J (1989) 1.80
Transcription attenuation associated with bacterial repetitive extragenic BIME elements. J Mol Biol (2001) 1.49
Construction of a series of pSAM2-based integrative vectors for use in actinomycetes. Gene (1990) 1.41
Plasmids in different strains of Streptomyces ambofaciens: free and integrated form of plasmid pSAM2. Mol Gen Genet (1984) 1.41
The unstable region of Streptomyces ambofaciens includes 210 kb terminal inverted repeats flanking the extremities of the linear chromosomal DNA. Mol Microbiol (1996) 1.37
The integrative element pSAM2 from Streptomyces: kinetics and mode of conjugal transfer. Mol Microbiol (2001) 1.34
Structural analysis of loci involved in pSAM2 site-specific integration in Streptomyces. Plasmid (1989) 1.24
Regulation of the expression of iso 2-cytochrome c gene in S. cerevisiae: cloning of the positive regulatory gene CYP1 and identification of the region of its target sequence on the structural gene CYP3. Mol Gen Genet (1985) 1.20
A quantitative UV laser footprinting analysis of the interaction of IHF with specific binding sites: re-evaluation of the effective concentration of IHF in the cell. J Mol Biol (1998) 1.19
In vivo cleavage of Escherichia coli BIME-2 repeats by DNA gyrase: genetic characterization of the target and identification of the cut site. Mol Microbiol (1997) 1.14
Transfer functions of the conjugative integrating element pSAM2 from Streptomyces ambofaciens: characterization of a kil-kor system associated with transfer. J Bacteriol (1993) 1.13
NKBOR, a mini-Tn10-based transposon for random insertion in the chromosome of Gram-negative bacteria and the rapid recovery of sequences flanking the insertion sites in Escherichia coli. Res Microbiol (2001) 1.09
Structure of the chromosomal insertion site for pSAM2: functional analysis in Escherichia coli. Mol Microbiol (1998) 1.04
Replicase, excisionase, and integrase genes of the Streptomyces element pSAM2 constitute an operon positively regulated by the pra gene. J Bacteriol (1998) 1.02
KorSA from the Streptomyces integrative element pSAM2 is a central transcriptional repressor: target genes and binding sites. J Bacteriol (2000) 1.00
Extreme resistance to potato virus X infection in plants expressing a modified component of the putative viral replicase. EMBO J (1993) 0.99
Identification of a gene encoding the replication initiator protein of the Streptomyces integrating element, pSAM2. Plasmid (1994) 0.99
Mode and origin of replication of pSAM2, a conjugative integrating element of Streptomyces ambofaciens. Mol Microbiol (1993) 0.99
The chromosomal integration site of the Streptomyces element pSAM2 overlaps a putative tRNA gene conserved among actinomycetes. Mol Gen Genet (1990) 0.99
Resistance to spiramycin in Streptomyces ambofaciens, the producer organism, involves at least two different mechanisms. J Gen Microbiol (1993) 0.97
In vivo interaction of the Escherichia coli integration host factor with its specific binding sites. Nucleic Acids Res (1995) 0.95
Characterization of pra, a gene for replication control in pSAM2, the integrating element of Streptomyces ambofaciens. Mol Microbiol (1995) 0.93
The macrolide-lincosamide-streptogramin B resistance phenotypes characterized by using a specifically deleted, antibiotic-sensitive strain of Streptomyces lividans. Antimicrob Agents Chemother (1996) 0.93
Characterization of lactic acid bacteria from musts and wines of three consecutive vintages of Ribeira Sacra. Lett Appl Microbiol (2011) 0.93
Excision and integration of a self-transmissible replicon of Streptomyces ambofaciens. Gene (1987) 0.93
Functional analysis of the Streptomyces ambofaciens element pSAM2. Plasmid (1991) 0.91
Characterization of a glycosyl transferase inactivating macrolides, encoded by gimA from Streptomyces ambofaciens. Antimicrob Agents Chemother (1998) 0.91
Complete conversion of antibiotic precursor to pristinamycin IIA by overexpression of Streptomyces pristinaespiralis biosynthetic genes. Nat Biotechnol (1997) 0.90
Kluyveromyces marxianus exhibits an ancestral Saccharomyces cerevisiae genome organization downstream of ADH2. Gene (2000) 0.86
Phage HK022 Roi protein inhibits phage lytic growth in Escherichia coli integration host factor mutants. J Bacteriol (1996) 0.85
[Isolation and fractionation of yeast deoxyribonucleic acid (DNA)]. C R Acad Sci Hebd Seances Acad Sci D (1966) 0.85
Stable yeast transformation with chimeric plasmids using a 2 micron-circular DNA-less strain as a recipient. Mol Gen Genet (1979) 0.82
[Electron microscope examination of mitochondrial DNA of yeast: molecules with 2 free ends]. C R Acad Sci Hebd Seances Acad Sci D (1968) 0.82
Amylase and chitinase genes in Streptomyces lividans are regulated by reg1, a pleiotropic regulatory gene. J Bacteriol (1997) 0.81
Anatomical basis of digital rectal examination. Surg Radiol Anat (2011) 0.79
Dispensable ribosomal resistance to spiramycin conferred by srmA in the spiramycin producer Streptomyces ambofaciens. Microbiology (1999) 0.79
Construction of efficient centromeric, multicopy and expression vectors for the yeast Kluyveromyces marxianus using homologous elements and the promoter of a purine-cytosine-like permease. J Mol Microbiol Biotechnol (1999) 0.79
amlC, another amylolytic gene maps close to the amlB locus in Streptomyces lividans TK24. Gene (1998) 0.78
Cloning of Frankia species putative tRNA(Pro) genes and their efficacy for pSAM2 site-specific integration in Streptomyces lividans. Appl Environ Microbiol (1994) 0.78
Comparison of the properties of the purified beta-glucosidase from the transformed strain of Saccharomyces cerevisiae TYKF2 with that of the donor strain Kluyveromyces fragilis Y610. Biotechnol Appl Biochem (1987) 0.77
Nucleotide sequence analysis of pRS2 and pRS3, two small cryptic plasmids from Oenococcus oeni. Plasmid (2001) 0.76
Cloning and characterization of a new alpha-amylase gene from Streptomyces lividans TK24. Gene (1997) 0.76
In vivo interaction of the Escherichia coli integration host factor with its specific binding sites. Nucleic Acids Res (1995) 0.76
Ultraviolet-laser footprinting. Methods Mol Biol (2001) 0.75
Basic characterization and partial purification of β-glucosidase from cell-free extracts of Oenococcus oeni ST81. Lett Appl Microbiol (2012) 0.75
Rearrangement of mitochondrial DNA molecules during the differentiation of mitochondria in yeast. II. - Labelling studies of the precursor product relationship. Biochimie (1975) 0.75
Construction of new yeast vectors and cloning of the nif (nitrogen fixation) gene cluster of Klebsiella pneumoniae in yeast. Curr Genet (1981) 0.75
Rearrangement of mitochondrial DNA molecules during the differentiation of mitochondria in yeast. I.-Electron microscopic studies of size and shape. Biochimie (1975) 0.75
[Study of the growth of microorganisms in the presence of benzo-3,4-pyrene and of benzo-1,2-pyrene]. C R Acad Sci Hebd Seances Acad Sci D (1967) 0.75
2 μm plasmid copy number in different yeast strains and repartition of endogenous and 2 μm chimeric plasmids in transformed strains. Curr Genet (1980) 0.75