Published in J Biol Chem on May 25, 1988
Diversity of the mammalian sodium/proton exchanger SLC9 gene family. Pflugers Arch (2003) 2.89
HCO 3--dependent volume regulation in alpha-cells of the rat endocrine pancreas. Pflugers Arch (2009) 0.75
Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor. Science (2001) 5.25
Amiloride and its analogs as tools in the study of ion transport. J Membr Biol (1988) 4.65
Analysis of flanking sequences from dissociation insertion lines: a database for reverse genetics in Arabidopsis. Plant Cell (1999) 3.65
Control of intracellular pH and growth by fibronectin in capillary endothelial cells. J Cell Biol (1990) 2.41
Tubular epithelial-myofibroblast transdifferentiation in progressive tubulointerstitial fibrosis in 5/6 nephrectomized rats. Kidney Int (1998) 2.35
Pyrazine diuretics. II. N-amidino-3-amino-5-substituted 6-halopyrazinecarboxamides. J Med Chem (1967) 1.76
Ethylene provides positional information on cortical cell division but is not involved in Nod factor-induced root hair tip growth in Rhizobium-legume interaction. Development (1997) 1.69
An aspartate conserved among G-protein receptors confers allosteric regulation of alpha 2-adrenergic receptors by sodium. J Biol Chem (1990) 1.61
Role of the Na+/H+ antiporter in rat proximal tubule bicarbonate absorption. J Clin Invest (1987) 1.59
Targeted ultrasound contrast agent for molecular imaging of inflammation in high-shear flow. Contrast Media Mol Imaging (2006) 1.58
Demonstration of a [K+,Cl-]-cotransport system in human red cells by its sensitivity to [(dihydroindenyl)oxy]alkanoic acids: regulation of cell swelling and distinction from the bumetanide-sensitive [Na+,K+,Cl-]-cotransport system. Mol Pharmacol (1988) 1.43
Endothelin-induced contraction of human peripheral resistance vessels is partly dependent on stimulation of sodium-hydrogen exchange. J Hypertens (1989) 1.41
Intracellular pH regulation in resting and contracting segments of rat mesenteric resistance vessels. J Physiol (1988) 1.39
Inhibition of Na+/Ca2+ exchange in membrane vesicle and papillary muscle preparations from guinea pig heart by analogs of amiloride. Proc Natl Acad Sci U S A (1984) 1.39
Peritoneal-uterine communication: a complication of prolonged embedding of a peritoneal catheter. Perit Dial Int (2012) 1.38
Inhibition of na/h antiport activity in sugar beet tonoplast by analogs of amiloride. Plant Physiol (1987) 1.36
Evidence that Na+/H+ exchange regulates receptor-mediated phospholipase A2 activation in human platelets. J Biol Chem (1986) 1.34
Regulation of human neutrophil chemotaxis by intracellular pH. J Biol Chem (1986) 1.34
Ethylisopropyl-amiloride: a new and highly potent derivative of amiloride for the inhibition of the Na+/H+ exchange system in various cell types. Biochem Biophys Res Commun (1983) 1.32
Structure-activity relationships of amiloride and certain of its analogues in relation to the blockade of the Na+/H+ exchange system. Mol Pharmacol (1984) 1.28
Developmental aspects of the Rhizobium-legume symbiosis. Plant Mol Biol (1992) 1.26
Purification and reconstitution of chloride channels from kidney and trachea. Science (1989) 1.25
Regulation of intracellular pH in human platelets. Effects of thrombin, A23187, and ionomycin and evidence for activation of Na+/H+ exchange and its inhibition by amiloride analogs. J Biol Chem (1986) 1.24
pH regulation in spread cells and round cells. J Biol Chem (1990) 1.22
Inhibition of Na+/Ca2+ exchange in pituitary plasma membrane vesicles by analogues of amiloride. Biochemistry (1985) 1.20
Role of protein kinase C and the Na+/H+ antiporter in suppression of apoptosis by granulocyte macrophage colony-stimulating factor and interleukin-3. J Biol Chem (1992) 1.19
Characterization of potent Na+/H+ exchange inhibitors from the amiloride series in A431 cells. Biochemistry (1984) 1.19
Inhibition of chemotactic factor-activated Na+/H+ exchange in human neutrophils by analogues of amiloride: structure-activity relationships in the amiloride series. Mol Pharmacol (1986) 1.18
Epithelial chloride channel. Development of inhibitory ligands. J Gen Physiol (1987) 1.17
Amiloride, a specific inhibitor for the Na+-driven flagellar motors of alkalophilic Bacillus. J Biol Chem (1988) 1.15
Inhibitors of Na+/H+ exchange block stimulus-provoked arachidonic acid release in human platelets. Selective effects on platelet activation by epinephrine, ADP, and lower concentrations of thrombin. J Biol Chem (1985) 1.13
Regulation of intracellular pH in cultured hippocampal neurons by an amiloride-insensitive Na+/H+ exchanger. J Biol Chem (1991) 1.13
Antibodies that recognize nitrotyrosine. Methods Enzymol (1996) 1.12
Thrombin activation of the Na+/H+ exchanger in vascular smooth muscle cells. Evidence for a kinase C-independent pathway which is Ca2+-dependent and pertussis toxin-sensitive. J Biol Chem (1987) 1.12
Specific inhibition of the Na(+)-driven flagellar motors of alkalophilic Bacillus strains by the amiloride analog phenamil. J Bacteriol (1990) 1.12
Intracranial metastases in the initial staging of bronchogenic carcinoma. Chest (1984) 1.11
Photolabeling of tonoplast from sugar beet cell suspensions by [h]5-(N-methyl-N-isobutyl)-amiloride, an inhibitor of the vacuolar na/h antiport. Plant Physiol (1990) 1.11
The pH of spontaneously beating cultured rat heart cells is regulated by an ATP-calmodulin-dependent Na+/H+ antiport. Circ Res (1989) 1.11
Rescue from programmed cell death in leukemic and normal myeloid cells. Blood (1991) 1.10
Glomerular epithelial-myofibroblast transdifferentiation in the evolution of glomerular crescent formation. Nephrol Dial Transplant (1999) 1.10
Amiloride and its analogs as tools to inhibit Na+ transport via the Na+ channel, the Na+/H+ antiport and the Na+/Ca2+ exchanger. Biochimie (1988) 1.09
Amiloride inhibits phorbol ester-stimulated Na+/H+ exchange and protein kinase C. An amiloride analog selectively inhibits Na+/H+ exchange. J Biol Chem (1985) 1.09
VsENOD5, VsENOD12 and VsENOD40 expression during Rhizobium-induced nodule formation on Vicia sativa roots. Plant Mol Biol (1995) 1.08
Effects of extracellular ATP on ion transport systems and [Ca2+]i in rat parotid acinar cells. Comparison with the muscarinic agonist carbachol. J Gen Physiol (1990) 1.08
Therapeutic potential of analogues of amiloride: inhibition of the regulation of intracellular pH as a possible mechanism of tumour selective therapy. Br J Cancer (1993) 1.07
Inhibitors of Na+/H+ exchange block epinephrine- and ADP-induced stimulation of human platelet phospholipase C by blockade of arachidonic acid release at a prior step. J Biol Chem (1986) 1.07
A case of intraperitoneal fracture of a double-cuff Tenckhoff catheter. Perit Dial Int (2014) 1.06
Estimation of the number and turnover rate of Na+/H+ exchangers in lymphocytes. Effect of phorbol ester and osmotic shrinking. J Biol Chem (1987) 1.05
Sequential pituitary MR imaging in Sheehan syndrome: report of 2 cases. AJNR Am J Neuroradiol (2008) 1.05
Tuberculosis in maintenance dialysis patients. Nephron (2001) 1.05
Evidence for a halide-binding site in halorhodopsin. J Biol Chem (1983) 1.04
Chemical modification of cell proliferation and fluid secretion in renal cysts. Kidney Int (1989) 1.03
NMR measurements of Na+ and cellular energy in ischemic rat heart: role of Na(+)-H+ exchange. Am J Physiol (1993) 1.03
Descending mesocolon defect herniation: case report. Changgeng Yi Xue Za Zhi (1999) 1.03
Blastocoel expansion in the preimplantation mouse embryo: role of extracellular sodium and chloride and possible apical routes of their entry. Dev Biol (1989) 1.02
Characterization of Na+-linked and Na+-independent Cl-/HCO3- exchange systems in Chinese hamster lung fibroblasts. J Biol Chem (1988) 1.02
Lanthanum carbonate (Fosrenol) efficacy and tolerability in the treatment of hyperphosphatemic patients with end-stage renal disease. Clin Nephrol (2005) 1.02
Glucocorticoid stimulation of ileal Na+ absorptive cell brush border Na+/H+ exchange and association with an increase in message for NHE-3, an epithelial Na+/H+ exchanger isoform. J Biol Chem (1993) 1.02
Primary pontine hemorrhage and the dysarthria-clumsy hand syndrome. Neurology (1982) 1.01
Relations among sodium pump inhibition, Na-Ca and Na-H exchange activities, and Ca-H interaction in cultured chick heart cells. Circ Res (1987) 1.01
Thrombin signal transduction mechanisms in rat vascular smooth muscle cells. Calcium and protein kinase C-dependent and -independent pathways. J Biol Chem (1990) 1.01
More evidence supports the association of PPP3CC with schizophrenia. Mol Psychiatry (2007) 1.01
A role for Na+/Ca2+ exchange in the generation of superoxide radicals by human neutrophils. J Biol Chem (1990) 1.01
Microtubule integrity is necessary for the epithelial barrier function of cultured thyroid cell monolayers. Exp Cell Res (1995) 1.00
Activation of the Na+/H+ and Cl-/HCO3- exchange by stimulation of acid secretion in the parietal cell. J Biol Chem (1988) 1.00
Bicarbonate determines cytoplasmic pH and suppresses mitogen-induced alkalinization in fibroblastic cells. J Biol Chem (1988) 1.00
Successive inactivation of the force-generating units of sodium-driven bacterial flagellar motors by a photoreactive amiloride analog. J Biol Chem (1994) 1.00
Activation of sodium-proton exchange is not a prerequisite for Ca2+ mobilization and aggregation in human platelets. FEBS Lett (1987) 0.99
Immunocytochemical and functional characterization of Na+ conductance in adult alveolar pneumocytes. Am J Physiol (1992) 0.99
Na+-Ca2+ exchange in human neutrophils. Am J Physiol (1988) 0.99
Na+-H+ exchanger of human placental brush-border membrane: identification and characterization. Am J Physiol (1986) 0.98
The control of mediator release from RBL-2H3 cells: roles for Ca2+, Na+, and protein kinase C1. J Immunol (1987) 0.98
Inhibition of epidermal growth factor-induced mitogenesis by amiloride and an analog: evidence against a requirement for Na+/H+ exchange. Proc Natl Acad Sci U S A (1984) 0.98
Na+/H+ exchanger activity in the pig kidney epithelial cell line, LLC-PK1: inhibition by amiloride and its derivatives. Biochem Biophys Res Commun (1985) 0.98
Vertebral hemangioma with compression fracture and paraparesis treated with preoperative embolization and vertebral resection. Spine (Phila Pa 1976) (1984) 0.98
Effects of muscarinic, alpha-adrenergic, and substance P agonists and ionomycin on ion transport mechanisms in the rat parotid acinar cell. The dependence of ion transport on intracellular calcium. J Gen Physiol (1989) 0.98
2-(Aminomethyl)phenols, a new class of saluretic agents. 1. Effects of nuclear substitution. J Med Chem (1980) 0.97
Chronic hypercapnia enhances Vmax of Na-H antiporter of renal brush-border membranes. Am J Physiol (1987) 0.97
Ca2+ mobilization can occur independent of acceleration of Na+/H+ exchange in thrombin-stimulated human platelets. J Biol Chem (1988) 0.96
Studies of pHi in rabbit esophageal basal and squamous epithelial cells in culture. Gastroenterology (1992) 0.96
Fetal lung epithelial cells contain two populations of amiloride-sensitive Na+ channels. Am J Physiol (1993) 0.96
Alpha 1-adrenoceptor stimulation increases intracellular pH and Ca2+ in cardiomyocytes through Na+/H+ and Na+/Ca2+ exchange. Eur J Pharmacol (1990) 0.96
Erythropoietin hyporesponsiveness: from iron deficiency to iron overload. Kidney Int Suppl (1999) 0.96
IP3- and cAMP-induced responses in isolated olfactory receptor neurons from the channel catfish. J Membr Biol (1992) 0.96
Intracellular-pH dependence of Na-H exchange and acid loading in quiescent and arginine vasopressin-activated mesangial cells. Proc Natl Acad Sci U S A (1990) 0.96
The pea late nodulin gene PsNOD6 is homologous to the early nodulin genes PsENOD3/14 and is expressed after the leghaemoglobin genes. Plant Mol Biol (1993) 0.96
Recombinant human interleukin 1-stimulated Na+/H+ exchange is not required for differentiation in pre-B lymphocyte cell line, 70Z/3. J Biol Chem (1987) 0.96
Mechanisms of HCl-induced lowering of intracellular pH in rabbit esophageal epithelial cells. Gastroenterology (1993) 0.95
The significance of the relative effects of loop diuretics and anti-brain edema agents on the Na+,K+,Cl- cotransport system and the Cl-/NaCO3- anion exchanger. Naunyn Schmiedebergs Arch Pharmacol (1986) 0.95
Local macrophage and myofibroblast proliferation in progressive renal injury in the rat remnant kidney. Nephrol Dial Transplant (1998) 0.95
Alpha 2-adrenergic receptors accelerate Na+/H+ exchange in neuroblastoma X glioma cells. J Biol Chem (1987) 0.95
Amiloride-sensitive Na+ pathways in capillary endothelial cell swelling during hemorrhagic shock. J Appl Physiol (1985) (1992) 0.95
Mechanism of the inhibitory action of phenelzine on microsomal drug metabolism. J Pharmacol Exp Ther (1981) 0.95
Extracellular ATP stimulates an amiloride-sensitive sodium influx in human lymphocytes. Arch Biochem Biophys (1990) 0.94
The root epidermis-specific pea gene RH2 is homologous to a pathogenesis-related gene. Plant Mol Biol (1994) 0.94
Inhibitors of glycolic acid oxidase. 4-substituted 2,4-dioxobutanoic acid derivatives. J Med Chem (1983) 0.94
Regulation of porcine brain alpha 2-adrenergic receptors by Na+,H+ and inhibitors of Na+/H+ exchange. J Biol Chem (1987) 0.94
Interleukin 2 induces a rapid increase in intracellular pH through activation of a Na+/H+ antiport. Cytoplasmic alkalinization is not required for lymphocyte proliferation. J Biol Chem (1985) 0.93
Early nodulin gene expression during Nod factor-induced processes in Vicia sativa. Plant J (1995) 0.93