Published in J Periodontal Res on July 01, 1988
Isolation and characterization of the Porphyromonas gingivalis prtT gene, coding for protease activity. Infect Immun (1993) 2.07
The multiple forms of trypsin-like activity present in various strains of Porphyromonas gingivalis are due to the presence of either Arg-gingipain or Lys-gingipain. Infect Immun (1995) 2.03
Bacterial collagenases and collagen-degrading enzymes and their potential role in human disease. Infect Immun (1996) 1.79
Characterization of the binding activities of proteinase-adhesin complexes from Porphyromonas gingivalis. J Bacteriol (1996) 1.69
Structural study on the free lipid A isolated from lipopolysaccharide of Porphyromonas gingivalis. J Bacteriol (1995) 1.61
Pathogenesis of periodontitis: a major arginine-specific cysteine proteinase from Porphyromonas gingivalis induces vascular permeability enhancement through activation of the kallikrein/kinin pathway. J Clin Invest (1994) 1.56
Identification of proteases from periodontopathogenic bacteria as activators of latent human neutrophil and fibroblast-type interstitial collagenases. Infect Immun (1992) 1.45
Specific cell components of Bacteroides gingivalis mediate binding and degradation of human fibrinogen. J Bacteriol (1991) 1.42
Cysteine protease of Porphyromonas gingivalis 381 enhances binding of fimbriae to cultured human fibroblasts and matrix proteins. Infect Immun (1996) 1.25
Biochemical characterization of the arginine-specific proteases of Porphyromonas gingivalis W50 suggests a common precursor. Biochem J (1997) 1.23
Porphyromonas gingivalis RgpA-Kgp proteinase-adhesin complexes penetrate gingival tissue and induce proinflammatory cytokines or apoptosis in a concentration-dependent manner. Infect Immun (2008) 1.18
Proteolytic inactivation of the leukocyte C5a receptor by proteinases derived from Porphyromonas gingivalis. Infect Immun (1996) 1.15
Targeted disruption of fibronectin-integrin interactions in human gingival fibroblasts by the RI protease of Porphyromonas gingivalis W50. Infect Immun (1999) 1.10
Purification and characterization of two forms of a high-molecular-weight cysteine proteinase (porphypain) from Porphyromonas gingivalis. J Bacteriol (1994) 1.09
Inflammatory cytokine gene expression in human periodontal ligament fibroblasts stimulated with bacterial lipopolysaccharides. Infect Immun (1995) 1.07
Purification and characterization of three types of proteases from culture supernatants of Porphyromonas gingivalis. Infect Immun (1991) 1.07
Purification and characterization of a protease from Porphyromonas gingivalis capable of degrading salt-solubilized collagen. Infect Immun (1993) 1.03
Emerging family of proline-specific peptidases of Porphyromonas gingivalis: purification and characterization of serine dipeptidyl peptidase, a structural and functional homologue of mammalian prolyl dipeptidyl peptidase IV. Infect Immun (2000) 0.97
Salivary histatin 5 is an inhibitor of both host and bacterial enzymes implicated in periodontal disease. Infect Immun (2001) 0.92
Purification and characterization of fibroblast-activating factor isolated from Porphyromonas gingivalis W50. Infect Immun (1993) 0.92
Expression of Arg-Gingipain RgpB is required for correct glycosylation and stability of monomeric Arg-gingipain RgpA from Porphyromonas gingivalis W50. Infect Immun (2005) 0.90
Purification and partial characterization of an elastolytic serine protease of Prevotella intermedia. Appl Environ Microbiol (1993) 0.88
Inducible expression of a Porphyromonas gingivalis W83 membrane-associated protease. Infect Immun (1997) 0.87
Purification of an 80,000-Mr glycylprolyl peptidase from Bacteroides gingivalis. Infect Immun (1989) 0.87
Inhibition of Porphyromonas gingivalis adhesion to Streptococcus gordonii by human submandibular-sublingual saliva. Infect Immun (1992) 0.87
Characterization of inhibitory effects of suspected periodontopathogens on osteogenesis in vitro. Infect Immun (1995) 0.84
Purification and characterization of arginine carboxypeptidase produced by Porphyromonas gingivalis. Infect Immun (2002) 0.83
Effect of Porphyromonas gingivalis on epithelial cell MMP-9 type IV collagenase production. Infect Immun (1996) 0.81
Modification of cystatin C activity by bacterial proteinases and neutrophil elastase in periodontitis. Mol Pathol (1997) 0.80
Evidence for polymorphonuclear leukocyte collagenase and 92-kilodalton gelatinase in gingival crevicular fluid. Infect Immun (1991) 0.79
Activities of the Porphyromonas gingivalis PrtP proteinase determined by construction of prtP-deficient mutants and expression of the gene in Bacteroides species. J Bacteriol (1999) 0.77
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Sodium and potassium conductance changes during a membrane action potential. J Physiol (1970) 2.94
Multiple modes of activation of latent human fibroblast collagenase: evidence for the role of a Cys73 active-site zinc complex in latency and a "cysteine switch" mechanism for activation. Proc Natl Acad Sci U S A (1990) 2.68
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Sodium channel activation in the squid giant axon. Steady state properties. J Gen Physiol (1985) 2.35
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Analysis of the effects of calcium or magnesium on voltage-clamp currents in perfused squid axons bathed in solutions of high potassium. J Gen Physiol (1969) 2.19
Assessment of risk for periodontal disease. II. Risk indicators for alveolar bone loss. J Periodontol (1995) 2.15
Distribution and kinetics of membrane dielectric polarization. II. Frequency domain studies of gating currents. J Gen Physiol (1982) 2.09
Positive MIBG scanning at the time of relapse in neuroblastoma which was MIBG negative at diagnosis. Br J Radiol (1997) 2.06
Recurrent tonsillitis. The role of Chlamydia and Mycoplasma. Arch Otolaryngol Head Neck Surg (1992) 2.04
Heterogeneity of virulence among strains of Bacteroides gingivalis. J Periodontal Res (1989) 1.99
Detergent-activation of latent collagenase and resolution of its component molecules. Biochem Biophys Res Commun (1982) 1.91
Simultaneous measurements of magnesium, calcium and sodium influxes in perfused squid giant axons under membrane potential control. J Physiol (1975) 1.80
Temperature effects on gating currents in the squid giant axon. Biophys J (1978) 1.78
Induced capacitance in the squid giant axon. Lipophilic ion displacement currents. J Gen Physiol (1983) 1.75
Sodium and gating current time shifts resulting from changes in initial conditions. J Gen Physiol (1983) 1.68
Sodium channel gating currents. Origin of the rising phase. J Gen Physiol (1987) 1.68
Clinical criteria for the definition of "established periodontitis". J Periodontol (1992) 1.65
Tissue localization of Actinobacillus actinomycetemcomitans in human periodontitis. I. Light, immunofluorescence and electron microscopic studies. J Periodontol (1987) 1.63
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Transforming growth factor-beta 1 up-regulates type IV collagenase expression in cultured human keratinocytes. J Biol Chem (1991) 1.59
Studies of leukotoxin from Actinobacillus actinomycetemcomitans using the promyelocytic HL-60 cell line. Infect Immun (1983) 1.53
Distinct populations of basal keratinocytes express stromelysin-1 and stromelysin-2 in chronic wounds. J Clin Invest (1994) 1.52
Actinobacillus actinomycetemcomitans in human periodontal disease. Association, serology, leukotoxicity, and treatment. J Periodontal Res (1982) 1.50
Evidence for the role of highly leukotoxic Actinobacillus actinomycetemcomitans in the pathogenesis of localized juvenile and other forms of early-onset periodontitis. J Periodontol (2000) 1.49
The rate of action of tetrodotoxin on sodium conductance in the squid giant axon. Philos Trans R Soc Lond B Biol Sci (1975) 1.47
NMR of laser-polarized xenon in human blood. Proc Natl Acad Sci U S A (1996) 1.46
Catabolism and turnover of collagens: collagenases. Methods Enzymol (1987) 1.44
Tumor cell-selective cytotoxicity of matrix metalloproteinase-activated anthrax toxin. Cancer Res (2000) 1.43
Gating currents associated with potassium channel activation. Nature (1982) 1.42
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Longitudinal study of prognostic factors in established periodontitis patients. J Clin Periodontol (1997) 1.36
Actinobacillus actinomycetemcomitans in the pathogenesis of human periodontal disease. Adv Dent Res (1988) 1.36
Sequence specificities of human fibroblast and neutrophil collagenases. J Biol Chem (1991) 1.34
Inactivating mutation of the mouse tissue inhibitor of metalloproteinases-2(Timp-2) gene alters proMMP-2 activation. J Biol Chem (2000) 1.31
Monoclonal antibodies to human fibroblast procollagenase. Inhibition of enzymatic activity, affinity purification of the enzyme, and evidence for clustering of epitopes in the NH2-terminal end of the activated enzyme. Biochemistry (1988) 1.30
Alanine scanning mutagenesis and functional analysis of the fibronectin-like collagen-binding domain from human 92-kDa type IV collagenase. J Biol Chem (1992) 1.28
Continuously recording fluorescent assays optimized for five human matrix metalloproteinases. Anal Biochem (1991) 1.28
Prevalence of periodontal pathogens in Brazilians with aggressive or chronic periodontitis. J Clin Periodontol (2005) 1.26
Activation and novel processing of matrix metalloproteinases by a thiol-proteinase from the oral anaerobe Porphyromonas gingivalis. J Dent Res (1997) 1.24
Sequence specificity of human skin fibroblast collagenase. Evidence for the role of collagen structure in determining the collagenase cleavage site. J Biol Chem (1987) 1.20
Rapid identification of periodontal pathogens in subgingival plaque: comparison of indirect immunofluorescence microscopy with bacterial culture for detection of Actinobacillus actinomycetemcomitans. J Dent Res (1985) 1.20
Protective immunization against experimental Bacteroides (Porphyromonas) gingivalis infection. Infect Immun (1990) 1.17
Cell type-specific regulation of SL-1 and SL-2 genes. Induction of the SL-2 gene but not the SL-1 gene by human keratinocytes in response to cytokines and phorbolesters. J Biol Chem (1993) 1.16
Effect of anaerobiosis on the surface ultrastructure and surface proteins of Actinobacillus actinomycetemcomitans (Haemophilus actinomycetemcomitans). Infect Immun (1987) 1.16
Etoposide as a single agent in relapsed advanced lymphomas. A phase II study. Cancer Chemother Pharmacol (1982) 1.15
Effect of chloroform on charge movement in the nerve membrane. Nature (1982) 1.15
Collagenase: localization in polymorphonuclear leukocyte granules in the rabbit. Science (1972) 1.15
Guided tissue regeneration and anti-infective therapy in the treatment of class II furcation defects. J Periodontol (1993) 1.14
Characterization of a polysaccharide antigen from Bacteroides gingivalis. J Immunol (1989) 1.14
The natural history of periodontal disease. The correlation of selected microbiological parameters with disease severity in Sri Lankan tea workers. J Clin Periodontol (1995) 1.13
Effect of immunization on experimental Bacteroides gingivalis infection in a murine model. Infect Immun (1987) 1.13
The origin of periodontal infections. Adv Dent Res (1988) 1.12
Time course of the sodium influx in squid giant axon during a single voltage clamp pulse. J Physiol (1970) 1.11
Tissue localization of Actinobacillus actinomycetemcomitans in human periodontitis. II. Correlation between immunofluorescence and culture techniques. J Periodontol (1987) 1.11
Human fibroblast collagenase-alpha-macroglobulin interactions. Localization of cleavage sites in the bait regions of five mammalian alpha-macroglobulins. J Biol Chem (1989) 1.10
Periodontal bone level and gingival proteinase activity in gnotobiotic rats immunized with Bacteroides gingivalis. Oral Microbiol Immunol (1991) 1.09
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In situ identification of bacterial species in marine microfouling films by using an immunofluorescence technique. Appl Environ Microbiol (1984) 1.07
A regulatory cascade involving retinoic acid, Cbfa1, and matrix metalloproteinases is coupled to the development of a process of perichondrial invasion and osteogenic differentiation during bone formation. J Cell Biol (2001) 1.07
Rapid identification of periodontal pathogens in subgingival dental plaque. Comparison of indirect immunofluorescence microscopy with bacterial culture for detection of Bacteroides gingivalis. J Periodontol (1985) 1.06
Investigations of the incidence of bovine trichomoniasis in nevada and of the efficacy of immunizing cattle with vaccines containing Tritrichomonas foetus. Theriogenology (1989) 1.05
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Blockade by pimozide of a noradrenaline sensitive adenylate cyclase in the limbic forebrain: possible role of limbic noradrenergic mechanisms in the mode of action of antipsychotics. J Pharm Pharmacol (1975) 1.04
Subgingival distribution of periodontal pathogenic microorganisms in adult periodontitis. J Periodontol (1992) 1.03
Procollagenase from bovine gingiva. Biochim Biophys Acta (1976) 1.03
Serology and tissue lesions in rabbits immunized with Streptococcus mutans. J Immunol (1983) 1.02
Immunochemistry and immunogenicity of low molecular weight human salivary mucin. Arch Oral Biol (1991) 1.02
Eikenella corrodens in the human oral cavity. J Periodontol (1989) 1.02
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Gingival manifestations of Wegener's granulomatosis. J Periodontol (1990) 1.01
Characterization and prevalence of Solobacterium moorei associated with oral halitosis. J Breath Res (2008) 1.00
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Identification and analysis of the gap region in the 23S ribosomal RNA from Actinobacillus actinomycetemcomitans. J Dent Res (1992) 1.00
The use of monoclonal antibodies to detect Bacteroides gingivalis in biological samples. Infect Immun (1986) 0.98
Characterization of 58-kilodalton human neutrophil collagenase: comparison with human fibroblast collagenase. Biochemistry (1990) 0.98
Purification and characterization of the serotype c antigen from Actinobacillus actinomycetemcomitans. Infect Immun (1984) 0.98