Composite biomarkers defined by multiparametric immunofluorescence analysis identify ALK-positive adenocarcinoma as a potential target for immunotherapy.

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Published in Oncoimmunology on February 21, 2017

Authors

Hélène Roussel1,2,3, Eléonore De Guillebon1,3,4, Lucie Biard5, Marion Mandavit1,3, Laure Gibault2, Elisabeth Fabre4, Martine Antoine6,7, Paul Hofman8, Michèle Beau-Faller9, Hélène Blons10, Claire Danel11, Françoise Le Pimpec Barthes12, Alain Gey1,13, Clémence Granier1,3,13, Marie Wislez7,14, Pierre Laurent-Puig10, Stéphane Oudard1,3,4, Patrick Bruneval2, Cécile Badoual1,2,3, Jacques Cadranel7,14, Eric Tartour1,3,13

Author Affiliations

1: INSERM U970, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
2: Department of Pathology, Hôpital Européen Georges Pompidou, Paris, France.
3: Equipe Labellisée Ligue Contre le Cancer, Paris, France.
4: Department of Oncology, Hôpital Européen Georges Pompidou, Paris, France.
5: Department of Biostatistics and Medical Information, Hôpital Saint Louis, Paris, France.
6: Department of Pathology, Hôpital Tenon, Paris, France.
7: GRC04 Théranoscan, Université P&M Curie, Paris, France.
8: Department of Pathology, Hôpital Pasteur, Nice, France.
9: Department of Biochemistry and Molecular Biology, Hôpital de Hautepierre Strasbourg, Strasbourg, France.
10: Department of Biochemistry and Molecular BiologyINSERM UMR-S 1147, Hôpital Européen Georges Pompidou, Paris, France.
11: Department of Pathology Pompidou, Hôpital Bichat, Paris, France.
12: Department of Thoracic Surgery, Hôpital Européen Georges Pompidou, Paris, France.
13: Service d'Immunologie biologique, Hôpital Européen Georges Pompidou, APHP, Paris, France.
14: Department of Pneumology, Hôpital Tenon, APHP, Paris, France.

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