Mapping the chromatin landscape and Blimp1 transcriptional targets that regulate trophoblast differentiation.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 28754907)

Published in Sci Rep on July 28, 2017

Authors

Andrew C Nelson1,2, Arne W Mould1, Elizabeth K Bikoff1, Elizabeth J Robertson3

Author Affiliations

1: Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK.
2: School of Life Sciences, Gibbet Hill Campus, University of Warwick, Coventry, CV4 7AL, UK.
3: Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK. elizabeth.robertson@path.ox.ac.uk.

Articles cited by this

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol (2009) 235.12

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A (2005) 167.46

Initial sequencing and comparative analysis of the mouse genome. Nature (2002) 96.15

Fast gapped-read alignment with Bowtie 2. Nat Methods (2012) 83.79

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet (2003) 53.59

Model-based analysis of ChIP-Seq (MACS). Genome Biol (2008) 51.63

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration. Brief Bioinform (2012) 23.58

Open source clustering software. Bioinformatics (2004) 23.17

GREAT improves functional interpretation of cis-regulatory regions. Nat Biotechnol (2010) 16.72

The UCSC Genome Browser Database: update 2006. Nucleic Acids Res (2006) 11.05

Stampy: a statistical algorithm for sensitive and fast mapping of Illumina sequence reads. Genome Res (2010) 9.55

Quantifying similarity between motifs. Genome Biol (2007) 9.27

FIMO: scanning for occurrences of a given motif. Bioinformatics (2011) 8.89

Promotion of trophoblast stem cell proliferation by FGF4. Science (1998) 8.02

Charting histone modifications and the functional organization of mammalian genomes. Nat Rev Genet (2010) 7.39

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position. Nat Methods (2013) 7.06

MEME-ChIP: motif analysis of large DNA datasets. Bioinformatics (2011) 6.52

Blimp1 is a critical determinant of the germ cell lineage in mice. Nature (2005) 5.49

DNA-binding specificities of human transcription factors. Cell (2013) 5.14

The UCSC Genome Browser database: 2015 update. Nucleic Acids Res (2014) 4.87

Implantation and the placenta: key pieces of the development puzzle. Science (1994) 4.75

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool. BMC Bioinformatics (2013) 4.73

Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells. Cell (1994) 4.60

DNA-binding specificity of GATA family transcription factors. Mol Cell Biol (1993) 4.34

An assessment of the developmental potential of embryonic stem cells in the midgestation mouse embryo. Development (1989) 3.90

seqMINER: an integrated ChIP-seq data interpretation platform. Nucleic Acids Res (2010) 3.74

Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2. Nat Immunol (2008) 3.55

The glial cells missing-1 protein is essential for branching morphogenesis in the chorioallantoic placenta. Nat Genet (2000) 3.49

Repression of c-myc transcription by Blimp-1, an inducer of terminal B cell differentiation. Science (1997) 2.93

The Hand1 bHLH transcription factor is essential for placentation and cardiac morphogenesis. Nat Genet (1998) 2.83

The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2016 update. Nucleic Acids Res (2016) 2.58

The zinc finger transcriptional repressor Blimp1/Prdm1 is dispensable for early axis formation but is required for specification of primordial germ cells in the mouse. Development (2005) 2.23

Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis. Proc Natl Acad Sci U S A (2010) 2.16

Chromatin modifiers and remodellers: regulators of cellular differentiation. Nat Rev Genet (2013) 1.98

Epidermal terminal differentiation depends on B lymphocyte-induced maturation protein-1. Proc Natl Acad Sci U S A (2007) 1.85

Maintenance of mouse trophoblast stem cell proliferation by TGF-beta/activin. Dev Biol (2004) 1.71

Distinct histone modifications in stem cell lines and tissue lineages from the early mouse embryo. Proc Natl Acad Sci U S A (2010) 1.64

Transcription factor AP-2gamma is essential in the extra-embryonic lineages for early postimplantation development. Development (2002) 1.62

Site-specific silencing of regulatory elements as a mechanism of X inactivation. Cell (2012) 1.54

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update. Nucleic Acids Res (2016) 1.52

Endogenous retroviruses function as species-specific enhancer elements in the placenta. Nat Genet (2013) 1.52

GATA-2 and GATA-3 regulate trophoblast-specific gene expression in vivo. Development (1997) 1.50

Development and function of trophoblast giant cells in the rodent placenta. Int J Dev Biol (2010) 1.47

ATAC-seq: A Method for Assaying Chromatin Accessibility Genome-Wide. Curr Protoc Mol Biol (2015) 1.44

The Apical Domain Is Required and Sufficient for the First Lineage Segregation in the Mouse Embryo. Dev Cell (2017) 1.43

The dynamic expression pattern of B lymphocyte induced maturation protein-1 (Blimp-1) during mouse embryonic development. Mech Dev (2002) 1.42

Examination of transcriptional networks reveals an important role for TCFAP2C, SMARCA4, and EOMES in trophoblast stem cell maintenance. Genome Res (2010) 1.41

The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes. Proc Natl Acad Sci U S A (2011) 1.40

A tripartite transcription factor network regulates primordial germ cell specification in mice. Nat Cell Biol (2013) 1.36

Interleukin-1 beta regulates human cytotrophoblast metalloproteinase activity and invasion in vitro. J Biol Chem (1994) 1.36

User-friendly solutions for microarray quality control and pre-processing on ArrayAnalysis.org. Nucleic Acids Res (2013) 1.35

Transcription factor gene AP-2 gamma essential for early murine development. Mol Cell Biol (2002) 1.33

LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation. EMBO J (2002) 1.31

GAT: a simulation framework for testing the association of genomic intervals. Bioinformatics (2013) 1.27

Identification of primary gene targets of TFAP2C in hormone responsive breast carcinoma cells. Genes Chromosomes Cancer (2010) 1.27

Human cytotrophoblast invasion is up-regulated by epidermal growth factor: evidence that paracrine factors modify this process. Dev Biol (1994) 1.21

Multiple roles of mouse Numb in tuning developmental cell fates. Curr Biol (2001) 1.20

The landscape of accessible chromatin in mammalian preimplantation embryos. Nature (2016) 1.13

Context-dependent wiring of Sox2 regulatory networks for self-renewal of embryonic and trophoblast stem cells. Mol Cell (2013) 1.11

An extended set of PRDM1/BLIMP1 target genes links binding motif type to dynamic repression. Nucleic Acids Res (2010) 1.07

Expression of matrix metalloproteinases 2 and 9 in human trophoblasts of normal and preeclamptic placentas: preliminary findings. Exp Mol Pathol (2009) 1.04

Supervillin couples myosin-dependent contractility to podosomes and enables their turnover. J Cell Sci (2012) 1.03

Derivation and maintenance of murine trophoblast stem cells under defined conditions. Stem Cell Reports (2014) 1.02

Quantitative Dynamics of Chromatin Remodeling during Germ Cell Specification from Mouse Embryonic Stem Cells. Cell Stem Cell (2015) 1.01

Multifunctional role of the transcription factor Blimp-1 in coordinating plasma cell differentiation. Nat Immunol (2016) 0.96

Stimulation of cortical myosin phosphorylation by p114RhoGEF drives cell migration and tumor cell invasion. PLoS One (2012) 0.96

Downregulation of DAB2IP results in cell proliferation and invasion and contributes to unfavorable outcomes in bladder cancer. Cancer Sci (2014) 0.95

Smad4-dependent pathways control basement membrane deposition and endodermal cell migration at early stages of mouse development. BMC Dev Biol (2009) 0.95

Lysine-specific demethylase 1 regulates differentiation onset and migration of trophoblast stem cells. Nat Commun (2014) 0.94

Immune balance at the foeto-maternal interface as the fulcrum of reproductive success. J Reprod Immunol (2013) 0.91

Development of the hemochorial maternal vascular spaces in the placenta through endothelial and vasculogenic mimicry. Dev Biol (2014) 0.89

Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells. Nat Commun (2015) 0.88

Placenta: The Forgotten Organ. Annu Rev Cell Dev Biol (2015) 0.88

Regulation of trophoblast invasion: the role of matrix metalloproteinases. Rev Obstet Gynecol (2012) 0.87

Reasons for diversity of placental structure. Placenta (2008) 0.87

Blimp1/Prdm1 governs terminal differentiation of endovascular trophoblast giant cells and defines multipotent progenitors in the developing placenta. Genes Dev (2012) 0.87

Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networks. Genes Dev (2015) 0.86

Frequent alterations of LOH11CR2A, PIG8 and CHEK1 genes at chromosomal 11q24.1-24.2 region in breast carcinoma: clinical and prognostic implications. Mol Oncol (2011) 0.83

Formation of atypical podosomes in extravillous trophoblasts regulates extracellular matrix degradation. Eur J Cell Biol (2012) 0.83

Trophoblasts regulate the placental hematopoietic niche through PDGF-B signaling. Dev Cell (2012) 0.82

BLIMP1 is required for postnatal epidermal homeostasis but does not define a sebaceous gland progenitor under steady-state conditions. Stem Cell Reports (2014) 0.81

Characterization and role of NUMB in the human extravillous trophopblast. Placenta (2011) 0.80

Blimp1/Prdm1 Functions in Opposition to Irf1 to Maintain Neonatal Tolerance during Postnatal Intestinal Maturation. PLoS Genet (2015) 0.79

The YY1/MMP2 axis promotes trophoblast invasion at the maternal-fetal interface. J Pathol (2016) 0.78

Single-cell RNA-seq reveals cell type-specific transcriptional signatures at the maternal-foetal interface during pregnancy. Nat Commun (2016) 0.77

The PR/SET domain zinc finger protein Prdm4 regulates gene expression in embryonic stem cells but plays a nonessential role in the developing mouse embryo. Mol Cell Biol (2013) 0.76

Expression of DAB2IP in human trophoblast and its role in trophoblast invasion. J Matern Fetal Neonatal Med (2015) 0.76

Tpbpa-Cre-mediated deletion of TFAP2C leads to deregulation of Cdkn1a, Akt1 and the ERK pathway, causing placental growth arrest. Development (2016) 0.76

Extravillous trophoblast cell invasion is promoted by the CD44-hyaluronic acid interaction. Placenta (2013) 0.75

p114RhoGEF governs cell motility and lumen formation during tubulogenesis through a ROCK-myosin-II pathway. J Cell Sci (2015) 0.75

The transcriptional repressor Blimp1 is expressed in rare luminal progenitors and is essential for mammary gland development. Development (2016) 0.75

A user-friendly workflow for analysis of Illumina gene expression bead array data available at the arrayanalysis.org portal. BMC Genomics (2015) 0.75