Merkel cell polyomavirus and Merkel cell carcinoma.

PubWeight™: 0.76‹?›

🔗 View Article (PMID 28893943)

Published in Philos Trans R Soc Lond B Biol Sci on October 19, 2017

Authors

James A DeCaprio1,2,3

Author Affiliations

1: Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.
2: Program in Virology, Graduate School of Arts and Sciences, Harvard University, Cambridge, Massachusetts, United States of America.
3: Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.

Articles citing this

Human oncogenic viruses: nature and discovery. Philos Trans R Soc Lond B Biol Sci (2017) 0.75

Articles cited by this

(truncated to the top 100)

Clonal integration of a polyomavirus in human Merkel cell carcinoma. Science (2008) 16.60

A papillomavirus DNA from a cervical carcinoma and its prevalence in cancer biopsy samples from different geographic regions. Proc Natl Acad Sci U S A (1983) 14.73

New human papovavirus (B.K.) isolated from urine after renal transplantation. Lancet (1971) 12.13

Cultivation of papova-like virus from human brain with progressive multifocal leucoencephalopathy. Lancet (1971) 11.92

Comprehensive molecular characterization of urothelial bladder carcinoma. Nature (2014) 8.48

Identification of a novel polyomavirus from patients with acute respiratory tract infections. PLoS Pathog (2007) 8.01

Identification of a third human polyomavirus. J Virol (2007) 7.06

T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus. Proc Natl Acad Sci U S A (2008) 4.74

Merkel cell carcinoma and HIV infection. Lancet (2002) 4.72

Merkel cell polyomavirus and two previously unknown polyomaviruses are chronically shed from human skin. Cell Host Microbe (2010) 3.78

Merkel cell carcinoma: changing incidence trends. J Surg Oncol (2005) 3.78

Trabecular carcinoma of the skin. Arch Dermatol (1972) 3.66

Discovery of a new human polyomavirus associated with trichodysplasia spinulosa in an immunocompromized patient. PLoS Pathog (2010) 3.15

PD-1 Blockade with Pembrolizumab in Advanced Merkel-Cell Carcinoma. N Engl J Med (2016) 2.54

Association of BK viruria with hemorrhagic cystitis in recipients of bone marrow transplants. N Engl J Med (1986) 2.47

Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulator. J Clin Invest (2011) 2.37

Quantitation of human seroresponsiveness to Merkel cell polyomavirus. PLoS Pathog (2009) 2.08

A novel human polyomavirus closely related to the african green monkey-derived lymphotropic polyomavirus. J Virol (2011) 2.03

Avelumab in patients with chemotherapy-refractory metastatic Merkel cell carcinoma: a multicentre, single-group, open-label, phase 2 trial. Lancet Oncol (2016) 1.82

JC virus granule cell neuronopathy: A novel clinical syndrome distinct from progressive multifocal leukoencephalopathy. Ann Neurol (2005) 1.79

Trabecular carcinoma of the skin: an ultrastructural study. Cancer (1978) 1.75

Discovery of STL polyomavirus, a polyomavirus of ancestral recombinant origin that encodes a unique T antigen by alternative splicing. Virology (2012) 1.75

Solid malignancies among patients in the Wegener's Granulomatosis Etanercept Trial. Arthritis Rheum (2006) 1.64

Improved detection suggests all Merkel cell carcinomas harbor Merkel polyomavirus. J Clin Invest (2012) 1.61

CDK1 substitutes for mTOR kinase to activate mitotic cap-dependent protein translation. Proc Natl Acad Sci U S A (2015) 1.61

Risk of merkel cell carcinoma after solid organ transplantation. J Natl Cancer Inst (2015) 1.59

Chaperone-mediated in vitro assembly of Polyomavirus capsids. Proc Natl Acad Sci U S A (2003) 1.56

The minimum replication origin of merkel cell polyomavirus has a unique large T-antigen loading architecture and requires small T-antigen expression for optimal replication. J Virol (2009) 1.52

Complete genome sequence of a tenth human polyomavirus. J Virol (2012) 1.48

Two cases of merkel cell tumour arising in patients with chronic lymphocytic leukaemia. Br J Dermatol (2000) 1.40

Distinct merkel cell polyomavirus molecular features in tumour and non tumour specimens from patients with merkel cell carcinoma. PLoS Pathog (2010) 1.40

New Structural Insights into the Genome and Minor Capsid Proteins of BK Polyomavirus using Cryo-Electron Microscopy. Structure (2016) 1.40

The etiology and epidemiology of merkel cell carcinoma. Curr Probl Cancer (2010) 1.39

Age-specific seroprevalences of merkel cell polyomavirus, human polyomaviruses 6, 7, and 9, and trichodysplasia spinulosa-associated polyomavirus. Clin Vaccine Immunol (2013) 1.36

Characteristic pattern of chromosomal gains and losses in Merkel cell carcinoma detected by comparative genomic hybridization. Cancer Res (1998) 1.35

Merkel cell polyomavirus encodes a microRNA with the ability to autoregulate viral gene expression. Virology (2008) 1.33

Identification of a novel polyomavirus in a pancreatic transplant recipient with retinal blindness and vasculitic myopathy. J Infect Dis (2014) 1.31

Merkel cell polyomavirus large T antigen disrupts host genomic integrity and inhibits cellular proliferation. J Virol (2013) 1.28

Merkel cell polyomavirus small T antigen controls viral replication and oncoprotein expression by targeting the cellular ubiquitin ligase SCFFbw7. Cell Host Microbe (2013) 1.27

Identification of a novel human polyomavirus in organs of the gastrointestinal tract. PLoS One (2013) 1.26

Chronic lymphocytic leukaemia patients have a high risk of Merkel-cell polyomavirus DNA-positive Merkel-cell carcinoma. Br J Cancer (2009) 1.26

Identification of an overprinting gene in Merkel cell polyomavirus provides evolutionary insight into the birth of viral genes. Proc Natl Acad Sci U S A (2013) 1.24

Cellular and viral factors regulating Merkel cell polyomavirus replication. PLoS One (2011) 1.21

Carcinogenicity of malaria and of some polyomaviruses. Lancet Oncol (2012) 1.19

Glycosaminoglycans and sialylated glycans sequentially facilitate Merkel cell polyomavirus infectious entry. PLoS Pathog (2011) 1.19

UV-Associated Mutations Underlie the Etiology of MCV-Negative Merkel Cell Carcinomas. Cancer Res (2015) 1.17

Mutational landscape of MCPyV-positive and MCPyV-negative Merkel cell carcinomas with implications for immunotherapy. Oncotarget (2016) 1.17

The SV40 large T antigen contains a decoy phosphodegron that mediates its interactions with Fbw7/hCdc4. J Biol Chem (2004) 1.16

Bypass of a protein barrier by a replicative DNA helicase. Nature (2012) 1.16

Merkel cell carcinoma after chronic lymphocytic leukemia: case report and literature review. Am J Clin Oncol (2003) 1.15

Merkel cell polyomavirus large T antigen has growth-promoting and inhibitory activities. J Virol (2013) 1.14

The Ancient Evolutionary History of Polyomaviruses. PLoS Pathog (2016) 1.12

Association between chronic lymphocytic leukaemia and secondary tumours: unusual occurrence of a neuroendocrine (Merkell cell) carcinoma. Eur Rev Med Pharmacol Sci (1998) 1.11

Bromodomain protein Brd4 plays a key role in Merkel cell polyomavirus DNA replication. PLoS Pathog (2012) 1.11

The Distinctive Mutational Spectra of Polyomavirus-Negative Merkel Cell Carcinoma. Cancer Res (2015) 1.07

Merkel cell polyomavirus infection occurs during early childhood and is transmitted between siblings. J Clin Virol (2013) 1.06

Tumor-specific T cells in human Merkel cell carcinomas: a possible role for Tregs and T-cell exhaustion in reducing T-cell responses. J Invest Dermatol (2013) 1.06

Nuclear localization of Merkel cell polyomavirus large T antigen in Merkel cell carcinoma. Virology (2010) 1.05

Different serologic behavior of MCPyV, TSPyV, HPyV6, HPyV7 and HPyV9 polyomaviruses found on the skin. PLoS One (2013) 1.05

Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice. J Invest Dermatol (2014) 1.03

Human polyomavirus 7-associated pruritic rash and viremia in transplant recipients. J Infect Dis (2014) 1.02

Epidemiology and survival of Merkel cell carcinoma in the Netherlands. A population-based study of 808 cases in 1993-2007. Eur J Cancer (2010) 1.01

The Merkel cell polyomavirus minor capsid protein. PLoS Pathog (2013) 1.01

Structures of Merkel cell polyomavirus VP1 complexes define a sialic acid binding site required for infection. PLoS Pathog (2012) 1.01

Merkel cell polyomavirus large T antigen disrupts lysosome clustering by translocating human Vam6p from the cytoplasm to the nucleus. J Biol Chem (2011) 1.01

Skin cancers associated with autoimmune conditions among elderly adults. Br J Cancer (2010) 1.00

Asymptomatic primary Merkel cell polyomavirus infection among adults. Emerg Infect Dis (2011) 0.99

Identification and validation of a novel mature microRNA encoded by the Merkel cell polyomavirus in human Merkel cell carcinomas. J Clin Virol (2011) 0.98

Characterization of an early passage Merkel cell polyomavirus-positive Merkel cell carcinoma cell line, MS-1, and its growth in NOD scid gamma mice. J Virol Methods (2012) 0.96

Seroepidemiology of Human Polyomaviruses in a US Population. Am J Epidemiol (2015) 0.96

Integration of TP53, DREAM, MMB-FOXM1 and RB-E2F target gene analyses identifies cell cycle gene regulatory networks. Nucleic Acids Res (2016) 0.93

Asymmetric assembly of Merkel cell polyomavirus large T-antigen origin binding domains at the viral origin. J Mol Biol (2011) 0.92

A Comprehensive Analysis of Replicating Merkel Cell Polyomavirus Genomes Delineates the Viral Transcription Program and Suggests a Role for mcv-miR-M1 in Episomal Persistence. PLoS Pathog (2015) 0.92

Merkel cell carcinoma arising after therapeutic immunosuppression. Br J Dermatol (1997) 0.91

Merkel cell polyomavirus small T antigen mRNA level is increased following in vivo UV-radiation. PLoS One (2010) 0.90

Dramatic Increase in the Incidence and Mortality from Merkel Cell Carcinoma in the United States. Am Surg (2015) 0.90

Trabecular carcinoma of the skin. A question of title. Am J Dermatopathol (1982) 0.89

High-affinity Rb binding, p53 inhibition, subcellular localization, and transformation by wild-type or tumor-derived shortened Merkel cell polyomavirus large T antigens. J Virol (2013) 0.89

Restricted protein phosphatase 2A targeting by Merkel cell polyomavirus small T antigen. J Virol (2015) 0.89

Tumorigenic activity of merkel cell polyomavirus T antigens expressed in the stratified epithelium of mice. Cancer Res (2015) 0.89

Characterization of functional domains in the Merkel cell polyoma virus Large T antigen. Int J Cancer (2014) 0.88

BK polyomavirus genotypes represent distinct serotypes with distinct entry tropism. J Virol (2013) 0.88

Rapid growth of Merkel cell carcinoma during etanercept treatment of psoriatic arthritis: cause or coincidence? Acta Derm Venereol (2011) 0.87

Comparisons between murine polyomavirus and Simian virus 40 show significant differences in small T antigen function. J Virol (2011) 0.87

Next generation sequencing of Cytokeratin 20-negative Merkel cell carcinoma reveals ultraviolet-signature mutations and recurrent TP53 and RB1 inactivation. Mod Pathol (2016) 0.84

Merkel Cell Polyomavirus Small T Antigen Induces Cancer and Embryonic Merkel Cell Proliferation in a Transgenic Mouse Model. PLoS One (2015) 0.84

New features of progressive multifocal leukoencephalopathy in the era of highly active antiretroviral therapy and natalizumab. J Neurovirol (2005) 0.84

WU polyomavirus in respiratory epithelial cells from lung transplant patient with Job syndrome. Emerg Infect Dis (2015) 0.83

Molecular epidemiology of merkel cell polyomavirus: evidence for geographically related variant genotypes. J Clin Microbiol (2014) 0.83

Rising incidence of Merkel cell carcinoma. J Plast Surg Hand Surg (2011) 0.83

Milestones in the staging, classification, and biology of Merkel cell carcinoma. J Natl Compr Canc Netw (2014) 0.82

Merkel Cell Polyomavirus Exhibits Dominant Control of the Tumor Genome and Transcriptome in Virus-Associated Merkel Cell Carcinoma. MBio (2017) 0.81

Seroprevalence of Merkel cell polyomavirus in the general rural population of Anyang, China. PLoS One (2014) 0.81

Shared Oncogenic Pathways Implicated in Both Virus-Positive and UV-Induced Merkel Cell Carcinomas. J Invest Dermatol (2016) 0.81

Increased incidence of malignant melanoma and other rare cutaneous cancers in the setting of chronic lymphocytic leukemia. Int J Dermatol (2015) 0.80

Adjuvant Radiation Therapy and Chemotherapy in Merkel Cell Carcinoma: Survival Analyses of 6908 Cases From the National Cancer Data Base. J Natl Cancer Inst (2016) 0.79

Role of Ultraviolet Radiation in Papillomavirus-Induced Disease. PLoS Pathog (2016) 0.79

Polyomavirus BK--a potential new therapeutic target for painful bladder syndrome/interstitial cystitis? Med Hypotheses (2014) 0.79

Production of recombinant VP1-derived virus-like particles from novel human polyomaviruses in yeast. BMC Biotechnol (2015) 0.78

The prevalence of STL polyomavirus in stool samples from Chinese children. J Clin Virol (2015) 0.78