Published in EMBO J on December 01, 1988
A precursor protein partly translocated into yeast mitochondria is bound to a 70 kd mitochondrial stress protein. EMBO J (1990) 2.56
SSC1, an essential member of the yeast HSP70 multigene family, encodes a mitochondrial protein. Mol Cell Biol (1989) 2.52
A yeast manganese transporter related to the macrophage protein involved in conferring resistance to mycobacteria. Proc Natl Acad Sci U S A (1996) 2.33
Sequential action of mitochondrial chaperones in protein import into the matrix. EMBO J (1991) 2.27
Protein import into yeast mitochondria is accelerated by the outer membrane protein MAS70. EMBO J (1990) 2.22
MPI1, an essential gene encoding a mitochondrial membrane protein, is possibly involved in protein import into yeast mitochondria. EMBO J (1992) 2.16
Protein import into mitochondria: ATP-dependent protein translocation activity in a submitochondrial fraction enriched in membrane contact sites and specific proteins. J Cell Biol (1989) 1.98
Import of proteins into yeast mitochondria: the nuclear MAS2 gene encodes a component of the processing protease that is homologous to the MAS1-encoded subunit. EMBO J (1988) 1.82
MAS5, a yeast homolog of DnaJ involved in mitochondrial protein import. Mol Cell Biol (1992) 1.76
Presequence and mature part of preproteins strongly influence the dependence of mitochondrial protein import on heat shock protein 70 in the matrix. J Cell Biol (1993) 1.73
MAS6 encodes an essential inner membrane component of the yeast mitochondrial protein import pathway. J Cell Biol (1993) 1.72
Import of ADP/ATP carrier into mitochondria: two receptors act in parallel. J Cell Biol (1990) 1.72
Inner membrane protease I, an enzyme mediating intramitochondrial protein sorting in yeast. EMBO J (1991) 1.56
The essential yeast protein MIM44 (encoded by MPI1) is involved in an early step of preprotein translocation across the mitochondrial inner membrane. Mol Cell Biol (1993) 1.43
Cleavage of precursors by the mitochondrial processing peptidase requires a compatible mature protein or an intermediate octapeptide. J Cell Biol (1991) 1.42
SMS1, a high-copy suppressor of the yeast mas6 mutant, encodes an essential inner membrane protein required for mitochondrial protein import. Mol Biol Cell (1994) 1.36
The single translation product of the FUM1 gene (fumarase) is processed in mitochondria before being distributed between the cytosol and mitochondria in Saccharomyces cerevisiae. Mol Cell Biol (1994) 1.32
The general mitochondrial processing peptidase from potato is an integral part of cytochrome c reductase of the respiratory chain. EMBO J (1992) 1.31
Tim18p is a new component of the Tim54p-Tim22p translocon in the mitochondrial inner membrane. Mol Biol Cell (2000) 1.31
Purification and characterization of a processing protease from rat liver mitochondria. EMBO J (1989) 1.23
Loss of mitochondrial hsp60 function: nonequivalent effects on matrix-targeted and intermembrane-targeted proteins. Mol Cell Biol (1993) 1.22
The general mitochondrial matrix processing protease from rat liver: structural characterization of the catalytic subunit. Proc Natl Acad Sci U S A (1990) 1.13
Identification of two structurally related proteins involved in proteolytic processing of precursors targeted to the chloroplast. EMBO J (1992) 1.12
Characterization of the mitochondrial inner membrane translocase complex: the Tim23p hydrophobic domain interacts with Tim17p but not with other Tim23p molecules. Mol Cell Biol (1998) 1.10
Role of the chaperonin cofactor Hsp10 in protein folding and sorting in yeast mitochondria. J Cell Biol (1994) 1.10
Targeting proteins to mitochondria: a current overview. Biochem J (1992) 1.00
Molecular chaperones and mitochondrial protein folding. J Bioenerg Biomembr (1997) 0.99
Rat liver mitochondrial intermediate peptidase (MIP): purification and initial characterization. EMBO J (1992) 0.98
Stromal processing peptidase binds transit peptides and initiates their ATP-dependent turnover in chloroplasts. J Cell Biol (1999) 0.96
Tim23p contains separate and distinct signals for targeting to mitochondria and insertion into the inner membrane. Mol Biol Cell (1998) 0.96
Presequence-dependent folding ensures MrpL32 processing by the m-AAA protease in mitochondria. EMBO J (2011) 0.94
MIP1, a new yeast gene homologous to the rat mitochondrial intermediate peptidase gene, is required for oxidative metabolism in Saccharomyces cerevisiae. Mol Cell Biol (1994) 0.89
The beta subunit of the mitochondrial processing peptidase from rat liver: cloning and sequencing of a cDNA and comparison with a proposed family of metallopeptidases. Proc Natl Acad Sci U S A (1993) 0.87
Functional reconstitution in Escherichia coli of the yeast mitochondrial matrix peptidase from its two inactive subunits. Proc Natl Acad Sci U S A (1993) 0.87
Sequence analysis of rat mitochondrial intermediate peptidase: similarity to zinc metallopeptidases and to a putative yeast homologue. Proc Natl Acad Sci U S A (1992) 0.83
Cytosolic and mitochondrial surface factor-independent import of a synthetic peptide into mitochondria. EMBO J (1991) 0.81
Isolation, characterization, and expression of the gene encoding the beta subunit of the mitochondrial processing peptidase from Blastocladiella emersonii. J Bacteriol (1998) 0.80
Mutational analysis of the potential catalytic residues of the VV G1L metalloproteinase. Virol J (2006) 0.77
The Cytochrome c Reductase Integrated Processing Peptidase from Potato Mitochondria Belongs to a New Class of Metalloendoproteases. Plant Physiol (1993) 0.77
Import of proteins into mitochondria. Cytochrome b2 and cytochrome c peroxidase are located in the intermembrane space of yeast mitochondria. J Biol Chem (1982) 12.07
Two nuclear mutations that block mitochondrial protein import in yeast. Proc Natl Acad Sci U S A (1984) 7.39
Binding of a specific ligand inhibits import of a purified precursor protein into mitochondria. Nature (1986) 5.58
Immunochemical identification of membrane proteins after sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Methods Enzymol (1983) 4.58
Protein translocation across membranes. Science (1988) 4.12
The amino-terminal region of an imported mitochondrial precursor polypeptide can direct cytoplasmic dihydrofolate reductase into the mitochondrial matrix. EMBO J (1984) 3.69
Transport of proteins into chloroplasts. Partial purification of a chloroplast protease involved in the processing of important precursor polypeptides. Eur J Biochem (1984) 3.30
Import of proteins into mitochondria. The precursor of cytochrome c1 is processed in two steps, one of them heme-dependent. J Biol Chem (1982) 3.26
Import of proteins into mitochondria. Partial purification of a matrix-located protease involved in cleavage of mitochondrial precursor polypeptides. J Biol Chem (1983) 2.81
Purification of microsomal signal peptidase as a complex. Proc Natl Acad Sci U S A (1986) 2.67
Mitochondrial protein import: identification of processing peptidase and of PEP, a processing enhancing protein. Cell (1988) 2.57
Imported mitochondrial proteins cytochrome b2 and cytochrome c1 are processed in two steps. Proc Natl Acad Sci U S A (1982) 2.39
A neutral metallo endoprotease involved in the processing of an F1-ATPase subunit precursor in mitochondria. J Biol Chem (1982) 2.28
The isolation of homogeneous leader peptidase from a strain of Escherichia coli which overproduces the enzyme. J Biol Chem (1982) 2.11
MAS1, a gene essential for yeast mitochondrial assembly, encodes a subunit of the mitochondrial processing protease. EMBO J (1988) 1.95
Processing peptidase of Neurospora mitochondria. Two-step cleavage of imported ATPase subunit 9. Eur J Biochem (1984) 1.73
Processing of pre-ornithine transcarbamylase requires a zinc-dependent protease localized to the mitochondrial matrix. Biochem Biophys Res Commun (1982) 1.67
A yeast mutant temperature-sensitive for mitochondrial assembly is deficient in a mitochondrial protease activity that cleaves imported precursor polypeptides. EMBO J (1985) 1.66
A mitochondrial protease that cleaves the precursor of ornithine carbamoyltransferase. Purification and properties. Eur J Biochem (1982) 1.54
Biogenesis of mitochondrial ubiquinol:cytochrome c reductase (cytochrome bc1 complex). Precursor proteins and their transfer into mitochondria. J Biol Chem (1982) 1.30
Purification and characterization of hen oviduct microsomal signal peptidase. Biochemistry (1987) 1.13
Control of metabolism in yeast and other lower eukaryotes through action of proteinases. Adv Microb Physiol (1980) 1.06
Characterization of a mitochondrial matrix protease catalyzing the processing of adrenodoxin precursor. J Biochem (1986) 0.91
Import of proteins into mitochondria. Cytochrome b2 and cytochrome c peroxidase are located in the intermembrane space of yeast mitochondria. J Biol Chem (1982) 12.07
Two nuclear mutations that block mitochondrial protein import in yeast. Proc Natl Acad Sci U S A (1984) 7.39
Biogenesis of mitochondria. Annu Rev Cell Biol (1988) 6.96
Binding of a specific ligand inhibits import of a purified precursor protein into mitochondria. Nature (1986) 5.58
Division versus fusion: Dnm1p and Fzo1p antagonistically regulate mitochondrial shape. J Cell Biol (1999) 5.53
Import of proteins into mitochondria: precursor forms of the extramitochondrially made F1-ATPase subunits in yeast. Proc Natl Acad Sci U S A (1979) 5.21
Import of proteins into mitochondria. Energy-dependent uptake of precursors by isolated mitochondria. J Biol Chem (1982) 4.25
Protein translocation across membranes. Science (1988) 4.12
Properties of avian retrovirus particles defective in viral protease. J Virol (1990) 4.03
Putting the HO gene to work: practical uses for mating-type switching. Methods Enzymol (1991) 3.79
The amino-terminal region of an imported mitochondrial precursor polypeptide can direct cytoplasmic dihydrofolate reductase into the mitochondrial matrix. EMBO J (1984) 3.69
How are proteins imported into mitochondria? Cell (1983) 3.69
Different import pathways through the mitochondrial intermembrane space for inner membrane proteins. EMBO J (1999) 3.58
Regulation of mitochondrial morphology and inheritance by Mdm10p, a protein of the mitochondrial outer membrane. J Cell Biol (1994) 3.53
Cytochromes c1 and b2 are sorted to the intermembrane space of yeast mitochondria by a stop-transfer mechanism. Cell (1992) 3.42
MMM1 encodes a mitochondrial outer membrane protein essential for establishing and maintaining the structure of yeast mitochondria. J Cell Biol (1994) 3.31
Import of proteins into mitochondria. The precursor of cytochrome c1 is processed in two steps, one of them heme-dependent. J Biol Chem (1982) 3.26
Directionality and regulation of cassette substitution in yeast. Cold Spring Harb Symp Quant Biol (1984) 3.23
Temperature-sensitive yeast mutants defective in mitochondrial inheritance. J Cell Biol (1990) 3.08
A 70-kd protein of the yeast mitochondrial outer membrane is targeted and anchored via its extreme amino terminus. EMBO J (1984) 2.96
A chemically synthesized pre-sequence of an imported mitochondrial protein can form an amphiphilic helix and perturb natural and artificial phospholipid bilayers. EMBO J (1986) 2.91
Import of proteins into mitochondria. Partial purification of a matrix-located protease involved in cleavage of mitochondrial precursor polypeptides. J Biol Chem (1983) 2.81
The cleavable prepiece of an imported mitochondrial protein is sufficient to direct cytosolic dihydrofolate reductase into the mitochondrial matrix. FEBS Lett (1984) 2.75
Gag3p, an outer membrane protein required for fission of mitochondrial tubules. J Cell Biol (2000) 2.62
A precursor protein partly translocated into yeast mitochondria is bound to a 70 kd mitochondrial stress protein. EMBO J (1990) 2.56
Yeast mitochondrial outer membrane specifically binds cytoplasmically-synthesized precursors of mitochondrial proteins. EMBO J (1983) 2.55
Mechanisms of failure of modular prostheses. Clin Orthop Relat Res (1992) 2.53
Cytochrome c oxidase from bakers' yeast. I. Isolation and properties. J Biol Chem (1973) 2.50
The outer membrane of yeast mitochondria: isolation of outside-out sealed vesicles. EMBO J (1983) 2.48
Import of proteins into mitochondria. Energy-dependent, two-step processing of the intermembrane space enzyme cytochrome b2 by isolated yeast mitochondria. J Biol Chem (1982) 2.46
Mdm12p, a component required for mitochondrial inheritance that is conserved between budding and fission yeast. J Cell Biol (1997) 2.44
Immunogenicity of hepatitis B Vaccines. Implications for persons at occupational risk of hepatitis B virus infection. Am J Prev Med (1998) 2.41
Imported mitochondrial proteins cytochrome b2 and cytochrome c1 are processed in two steps. Proc Natl Acad Sci U S A (1982) 2.39
Mitochondrial proteins essential for viability mediate protein import into yeast mitochondria. Nature (1991) 2.37
Import of proteins into mitochondria. Yeast cells grown in the presence of carbonyl cyanide m-chlorophenylhydrazone accumulate massive amounts of some mitochondrial precursor polypeptides. J Biol Chem (1982) 2.34
Import of proteins into mitochondria: a 70 kilodalton outer membrane protein with a large carboxy-terminal deletion is still transported to the outer membrane. EMBO J (1983) 2.33
Isolation of the nuclear yeast genes for citrate synthase and fifteen other mitochondrial proteins by a new screening method. EMBO J (1984) 2.33
Mmm1p, a mitochondrial outer membrane protein, is connected to mitochondrial DNA (mtDNA) nucleoids and required for mtDNA stability. J Cell Biol (2001) 2.28
The yeast dynamin-like protein, Mgm1p, functions on the mitochondrial outer membrane to mediate mitochondrial inheritance. J Cell Biol (1999) 2.28
Analysis of mitochondrial function and assembly. Methods Enzymol (1991) 2.27
Sequential action of mitochondrial chaperones in protein import into the matrix. EMBO J (1991) 2.27
Import of mitochondrial carriers mediated by essential proteins of the intermembrane space. Science (1998) 2.27
Heme is necessary for the accumulation and assembly of cytochrome c oxidase subunits in Saccharomyces cerevisiae. J Biol Chem (1978) 2.25
Structure-function comparisons of the proapoptotic protein Bax in yeast and mammalian cells. Mol Cell Biol (1996) 2.24
Protein import into yeast mitochondria is accelerated by the outer membrane protein MAS70. EMBO J (1990) 2.22
UGO1 encodes an outer membrane protein required for mitochondrial fusion. J Cell Biol (2001) 2.18
A 42K outer-membrane protein is a component of the yeast mitochondrial protein import site. Nature (1989) 2.18
Mitochondrial presequences. J Biol Chem (1988) 2.18
Division of mitochondria requires a novel DMN1-interacting protein, Net2p. Mol Biol Cell (2001) 2.17
The presequences of two imported mitochondrial proteins contain information for intracellular and intramitochondrial sorting. Cell (1986) 2.14
Energy-dependent processing of cytoplasmically made precursors to mitochondrial proteins. Proc Natl Acad Sci U S A (1979) 2.14
Import of proteins into mitochondria. Extramitochondrial pools and post-translational import of mitochondrial protein precursors in vivo. J Biol Chem (1982) 2.12
Artificial mitochondrial presequences. Proc Natl Acad Sci U S A (1986) 2.11
Both ATP and an energized inner membrane are required to import a purified precursor protein into mitochondria. EMBO J (1987) 2.08
The first twelve amino acids of a yeast mitochondrial outer membrane protein can direct a nuclear-coded cytochrome oxidase subunit to the mitochondrial inner membrane. EMBO J (1985) 2.06
A yeast mutant lacking mitochondrial manganese-superoxide dismutase is hypersensitive to oxygen. Proc Natl Acad Sci U S A (1986) 2.01
Corrosion at the interface of cobalt-alloy heads on titanium-alloy stems. Clin Orthop Relat Res (1991) 2.01
A purified precursor polypeptide requires a cytosolic protein fraction for import into mitochondria. EMBO J (1984) 1.99
Protein import into mitochondria: ATP-dependent protein translocation activity in a submitochondrial fraction enriched in membrane contact sites and specific proteins. J Cell Biol (1989) 1.98
Subunit IV of yeast cytochrome c oxidase: cloning and nucleotide sequencing of the gene and partial amino acid sequencing of the mature protein. EMBO J (1984) 1.97
Import of proteins into mitochondria: nucleotide sequence of the gene for a 70-kd protein of the yeast mitochondrial outer membrane. EMBO J (1983) 1.97
A role for ubiquitination in mitochondrial inheritance in Saccharomyces cerevisiae. J Cell Biol (1999) 1.97
MAS1, a gene essential for yeast mitochondrial assembly, encodes a subunit of the mitochondrial processing protease. EMBO J (1988) 1.95
DNA-protein conjugates can enter mitochondria via the protein import pathway. Nature (1989) 1.95
Amphiphilicity is essential for mitochondrial presequence function. EMBO J (1988) 1.93
Nuclear and mitochondrial inheritance in yeast depends on novel cytoplasmic structures defined by the MDM1 protein. J Cell Biol (1992) 1.90
Mas37p, a novel receptor subunit for protein import into mitochondria. J Cell Biol (1995) 1.89
A two-subunit cytochrome c oxidase (cytochrome aa3) from Paracoccus dentrificans. Proc Natl Acad Sci U S A (1980) 1.88
Mitochondria: a historical review. J Cell Biol (1981) 1.88
Dynamic interaction between Isp45 and mitochondrial hsp70 in the protein import system of the yeast mitochondrial inner membrane. Proc Natl Acad Sci U S A (1994) 1.87
Prohibitin family members interact genetically with mitochondrial inheritance components in Saccharomyces cerevisiae. Mol Cell Biol (1998) 1.85
Mitochondrial assembly in respiration-deficient mutants of Saccharomyces cerevisiae. II. Effect of nuclear and extrachromosomal mutations on the formation of cytochrome c oxidase. J Biol Chem (1973) 1.85
ATP-dependent proteases that also chaperone protein biogenesis. Trends Biochem Sci (1997) 1.85
Import of proteins into mitochondria. Annu Rev Genet (1991) 1.84
Protein unfolding and the energetics of protein translocation across biological membranes. Cell (1988) 1.84
A chimeric mitochondrial precursor protein with internal disulfide bridges blocks import of authentic precursors into mitochondria and allows quantitation of import sites. J Cell Biol (1988) 1.83
A yeast mitochondrial outer membrane protein essential for protein import and cell viability. Nature (1990) 1.82
Import of proteins into yeast mitochondria: the nuclear MAS2 gene encodes a component of the processing protease that is homologous to the MAS1-encoded subunit. EMBO J (1988) 1.82
Requirement for the yeast gene LON in intramitochondrial proteolysis and maintenance of respiration. Science (1994) 1.82
The Tim54p-Tim22p complex mediates insertion of proteins into the mitochondrial inner membrane. J Cell Biol (1997) 1.80
Promitochondria of anaerobically grown yeast. I. Isolation and biochemical properties. Biochemistry (1969) 1.79
MAS5, a yeast homolog of DnaJ involved in mitochondrial protein import. Mol Cell Biol (1992) 1.76
Intermediate filament formation by a yeast protein essential for organelle inheritance. Science (1993) 1.75
Unfolding and refolding of a purified precursor protein during import into isolated mitochondria. EMBO J (1988) 1.75
The cytoplasmically-made subunit IV is necessary for assembly of cytochrome c oxidase in yeast. EMBO J (1985) 1.75
A mutation in the yeast heat-shock factor gene causes temperature-sensitive defects in both mitochondrial protein import and the cell cycle. Mol Cell Biol (1991) 1.75
MAS6 encodes an essential inner membrane component of the yeast mitochondrial protein import pathway. J Cell Biol (1993) 1.72
Cytochrome c oxidase from bakers' yeast. II. Site of translation of the protein components. J Biol Chem (1973) 1.71
Functional cooperation of mitochondrial protein import receptors in yeast. EMBO J (1993) 1.71
Import of proteins into mitochondria. Translatable mRNAs for imported mitochondrial proteins are present in free as well as mitochondria-bound cytoplasmic polysomes. J Biol Chem (1982) 1.70
Protein translocation across mitochondrial membranes: what a long, strange trip it is. Cell (1995) 1.70
Energy transfer and charge separation kinetics in photosystem I: Part 1: Picosecond transient absorption and fluorescence study of cyanobacterial photosystem I particles. Biophys J (1993) 1.69
Cytochrome c oxidase from bakers' yeast. III. Physical characterization of isolated subunits and chemical evidence for two different classes of polypeptides. J Biol Chem (1975) 1.68