Published in Biochem Biophys Res Commun on May 14, 1986
A novel tumour promoter, thapsigargin, transiently increases cytoplasmic free Ca2+ without generation of inositol phosphates in NG115-401L neuronal cells. Biochem J (1988) 2.49
Calcium and cyclic adenosine monophosphate as second messengers for vasopressin in the rat inner medullary collecting duct. J Clin Invest (1988) 1.78
Receptor coupled events in bradykinin action: rapid production of inositol phosphates and regulation of cytosolic free Ca2+ in a neural cell line. EMBO J (1987) 1.59
Calcium release from separate receptor-specific intracellular stores induced by histamine and ATP in a hamster cell line. J Physiol (1992) 0.99
Measurement of cytoplasmic free Ca2+ concentration in rabbit aorta using the photoprotein, aequorin. Effect of atrial natriuretic peptide on agonist-induced Ca2+ signal generation. J Clin Invest (1987) 0.98
Neurotransmitter release from bradykinin-stimulated PC12 cells. Stimulation of cytosolic calcium and neurotransmitter release. Biochem J (1989) 0.80
Temporal changes in the calcium-dependence of the histamine H1-receptor-stimulation of cyclic AMP accumulation in guinea-pig cerebral cortex. Br J Pharmacol (1989) 0.77
The oligosaccharide component of alpha 1-adrenergic receptors from BC3H1 and DDT1 muscle cells. Studies with glycosidases and photoaffinity labelling of intact cells. Biochem J (1988) 0.75
Alkalinization stimulates the purified plasma-membrane Ca2+ pump by increasing its Ca2+ affinity. Biochem J (1989) 0.75
Endothelin stimulates phospholipase C, Na+/H+ exchange, c-fos expression, and mitogenesis in rat mesangial cells. J Clin Invest (1989) 2.17
Towards a revised nomenclature for P1 and P2 receptors. Trends Pharmacol Sci (1997) 2.09
Isoquinolines as antagonists of the P2X7 nucleotide receptor: high selectivity for the human versus rat receptor homologues. Mol Pharmacol (1998) 1.94
Detection of local ATP release from activated platelets using cell surface-attached firefly luciferase. Am J Physiol (1999) 1.94
The insulin-mimetic effects of vanadate in isolated rat adipocytes. Dissociation from effects of vanadate as a (Na+-K+)ATPase inhibitor. J Biol Chem (1980) 1.71
Intracellular Ca2+ mobilization activated by extracellular ATP in Ehrlich ascites tumor cells. J Biol Chem (1985) 1.53
Modulation of P2X7 nucleotide receptor expression by pro- and anti-inflammatory stimuli in THP-1 monocytes. J Leukoc Biol (1998) 1.45
Maitotoxin and P2Z/P2X(7) purinergic receptor stimulation activate a common cytolytic pore. Am J Physiol (1999) 1.44
Different calcium dependence of the capping and cutting activities of villin. J Biol Chem (1986) 1.41
Induction of the P2z/P2X7 nucleotide receptor and associated phospholipase D activity by lipopolysaccharide and IFN-gamma in the human THP-1 monocytic cell line. J Immunol (1996) 1.41
Calcium is a key signaling molecule in beta-lapachone-mediated cell death. J Biol Chem (2001) 1.39
Cutting edge: the nucleotide receptor P2X7 contains multiple protein- and lipid-interaction motifs including a potential binding site for bacterial lipopolysaccharide. J Immunol (2001) 1.37
Marek's disease virus (MDV) encodes an interleukin-8 homolog (vIL-8): characterization of the vIL-8 protein and a vIL-8 deletion mutant MDV. J Virol (2001) 1.34
Design, synthesis, and biological characterization of a peptide-mimetic antagonist for a tethered-ligand receptor. Proc Natl Acad Sci U S A (1999) 1.33
Extracellular ATP activates polyphosphoinositide breakdown and Ca2+ mobilization in Ehrlich ascites tumor cells. Arch Biochem Biophys (1986) 1.30
Stress-activated protein kinase/JNK activation and apoptotic induction by the macrophage P2X7 nucleotide receptor. J Biol Chem (2000) 1.28
Regulation of P2X(7) nucleotide receptor function in human monocytes by extracellular ions and receptor density. Am J Physiol Cell Physiol (2001) 1.28
Mitogenic signals for platelet-derived growth factor isoforms in liver fat-storing cells. Am J Physiol (1991) 1.24
Novel kinetics of single cell Ca2+ transients in stimulated hepatocytes and A10 cells measured using fura-2 and fluorescent videomicroscopy. J Biol Chem (1988) 1.23
Differential activation of cation channels and non-selective pores by macrophage P2z purinergic receptors expressed in Xenopus oocytes. J Biol Chem (1994) 1.23
Histamine-induced calcium release and phorbol antagonism in cultured airway smooth muscle cells. Am J Physiol (1987) 1.20
Evidence for two distinct G-protein-coupled ADP receptors mediating platelet activation. Thromb Haemost (1999) 1.19
Stage-specific expression of P2Y receptors, ecto-apyrase, and ecto-5'-nucleotidase in myeloid leukocytes. Am J Physiol (1997) 1.16
A novel pathway for the activation of phospholipase D by P2z purinergic receptors in BAC1.2F5 macrophages. J Biol Chem (1992) 1.14
Extracellular adenosine triphosphate activates calcium mobilization in human phagocytic leukocytes and neutrophil/monocyte progenitor cells. J Clin Invest (1989) 1.14
Endothelin is a positive inotropic agent in human and rat heart in vitro. Biochem Biophys Res Commun (1989) 1.08
Storage of dopamine and acetylcholine in granules of PC12, a clonal pheochromocytoma cell line. Biochemistry (1980) 1.06
Extracellular mutations of protease-activated receptor-1 result in differential activation by thrombin and thrombin receptor agonist peptide. Mol Pharmacol (2000) 1.06
Immunohistochemical evidence for ATP receptors in human dental pulp. J Dent Res (2001) 1.04
Endotoxin activation of macrophages does not induce ATP release and autocrine stimulation of P2 nucleotide receptors. J Immunol (2000) 1.03
The P2X1 receptor, an adenosine triphosphate-gated cation channel, is expressed in human platelets but not in human blood leukocytes. Blood (1998) 1.03
Effects of PDGF on inositol phosphates, Ca2+, and contraction of mesangial cells. Am J Physiol (1987) 1.02
Phosphorus-31 nuclear magnetic resonance studies of single muscle cells isolated from barnacle depressor muscle. Biochemistry (1983) 0.96
Guanine-nucleotide- and adenine-nucleotide-dependent regulation of phospholipase D in electropermeabilized HL-60 granulocytes. Biochem J (1991) 0.95
In vitro and in vivo studies with a series of hexapeptide endothelin antagonists. J Cardiovasc Pharmacol (1993) 0.94
Resident and faculty adherence to common guidelines. Acad Med (2001) 0.94
Agonist-induced changes in the properties of beta-adrenergic receptors on intact S49 lymphoma cells. Time-dependent changes in the affinity of the receptor for agonists. Mol Pharmacol (1984) 0.94
Pertussis toxin produces differential inhibitory effects on basal, P2-purinergic, and chemotactic peptide-stimulated inositol phospholipid breakdown in HL-60 cells and HL-60 cell membranes. J Biol Chem (1990) 0.94
Azaphilones with endothelin receptor binding activity produced by Penicillium sclerotiorum: taxonomy, fermentation, isolation, structure elucidation and biological activity. J Antibiot (Tokyo) (1995) 0.94
Extracellular adenosine triphosphate increases cation permeability of chronic lymphocytic leukemic lymphocytes. Blood (1989) 0.93
Expression of the pore-forming P2Z purinoreceptor in Xenopus oocytes injected with poly(A)+ RNA from murine macrophages. Mol Pharmacol (1993) 0.92
Regulation of phospholipase D and primary granule secretion by P2-purinergic- and chemotactic peptide-receptor agonists is induced during granulocytic differentiation of HL-60 cells. J Clin Invest (1991) 0.91
Calcium currents in the A7r5 smooth muscle-derived cell line. Pflugers Arch (1990) 0.90
Chronic treatment with P2-purinergic receptor agonists induces phenotypic modulation of the HL-60 and U937 human myelogenous leukemia cell lines. J Leukoc Biol (1991) 0.90
Stimulation of cytosolic free calcium and inositol phosphates by prostaglandins in cultured rat mesangial cells. Biochem Biophys Res Commun (1987) 0.89
Down regulation of beta adrenergic receptors in S49 lymphoma cells induced by atypical agonists. J Pharmacol Exp Ther (1986) 0.89
Discovery and optimization of a novel series of thrombin receptor (par-1) antagonists: potent, selective peptide mimetics based on indole and indazole templates. J Med Chem (2001) 0.88
Dissociation of the pore-forming and phospholipase D activities stimulated via P2z purinergic receptors in BAC1.2F5 macrophages. Product inhibition of phospholipase D enzyme activity. J Biol Chem (1993) 0.88
Tumor cell resistance to topoisomerase II poisons: role for intracellular free calcium in the sensitization by inhibitors or calcium-calmodulin-dependent enzymes. Biochem Pharmacol (1998) 0.87
Down-regulation of P2U-purinergic nucleotide receptor messenger RNA expression during in vitro differentiation of human myeloid leukocytes by phorbol esters or inflammatory activators. Mol Pharmacol (1997) 0.87
Immune complex activation of rat glomerular mesangial cells: dependence on the Fc region of antibody. Am J Physiol (1989) 0.86
Novel tricyclic benzothiazolo[2,3-c]thiadiazine antagonists of the platelet ADP receptor (P2Y(12)). Bioorg Med Chem Lett (2001) 0.85
Identification and transmembrane signaling of leukotriene D4 receptors in human mesangial cells. Am J Physiol (1988) 0.84
Sarcoplasmic Ca2+ transients during the contractile cycle of single barnacle muscle fibres: measurements with arsenazo III-injected fibres. J Muscle Res Cell Motil (1982) 0.84
Elevation of cytosolic free calcium by platelet-activating factor in cultured rat mesangial cells. FASEB J (1987) 0.84
ATP-induced potentiation of G-protein-dependent phospholipase D activity in a cell-free system from U937 promonocytic leukocytes. J Biol Chem (1993) 0.83
Relationship between intrinsic activities of agonists in normal and desensitized tissue and agonist-induced loss of beta adrenergic receptors. J Pharmacol Exp Ther (1984) 0.83
Activation of calcium mobilization and calcium influx by alpha 1-adrenergic receptors in a smooth muscle cell line. Biochem Biophys Res Commun (1985) 0.83
Endothelin-1 activates the phosphoinositide cascade in cultured glomerular mesangial cells. J Cardiovasc Pharmacol (1989) 0.82
Effect of atrial natriuretic factor on cytosolic free calcium in rat glomerular mesangial cells. FEBS Lett (1987) 0.82
Angiotensin II activates the beta 1 isoform of phospholipase C in vascular smooth muscle cells. Am J Physiol (1997) 0.82
Focus on "multiple functional P2X and P2Y receptors in the luminal and basolateral membranes of pancreatic duct cells". Am J Physiol (1999) 0.81
Adenosine 5'-triphosphate independent secretion from PC12 pheochromocytoma cells. Biochemistry (1982) 0.81
Oxytocin activates the inositol-phospholipid-protein kinase-C system and stimulates prostaglandin production in human amnion cells. Endocrinology (1988) 0.81
Adenosine triphosphate activates the phospholipase-C cascade system in human amnion cells without increasing prostaglandin production. Endocrinology (1989) 0.81
Endothelin B receptors on human endothelial and smooth-muscle cells show equivalent binding pharmacology. J Cardiovasc Pharmacol (1998) 0.79
Induction of GLUT-1 mRNA in response to inhibition of oxidative phosphorylation: role of increased [Ca2+]i. Am J Physiol (1996) 0.79
Inhibition of tension development and actomyosin ATPase activity in barnacle muscle by the Ca2+-indicator dye antipyrylazo III. J Muscle Res Cell Motil (1985) 0.78
Functional expression of the parathyroid cell calcium receptor in Xenopus oocytes. FEBS Lett (1993) 0.78
Fluorescence-polarization measurements on normal and mutant human skin fibroblasts. Arch Biochem Biophys (1978) 0.78
Interactions of agonists with beta-adrenergic receptors on S49 lymphoma cells. Adv Cyclic Nucleotide Protein Phosphorylation Res (1985) 0.78
Phospholipase C activation by prostaglandins and thromboxane A2 in cultured mesangial cells. Am J Physiol (1988) 0.78
Endothelin and PDGF enhance arachidonic acid release and DNA synthesis in vascular smooth muscle cells. Am J Physiol (1996) 0.77
Novel drimane sesquiterpene esters from Aspergillus ustus var. pseudodeflectus with endothelin receptor binding activity. J Antibiot (Tokyo) (1996) 0.77
Structure-activity relationships in a series of orally active gamma-hydroxy butenolide endothelin antagonists. J Med Chem (1997) 0.77
Stimulation of GLUT-1 glucose transporter expression in response to exposure to calcium ionophore A-23187. Am J Physiol (1995) 0.76
Annexin II inhibition of G protein-regulated inositol trisphosphate formation in rat aortic smooth muscle. Am J Physiol (1996) 0.76
Flow cytometric measurements of cytosolic [Ca2+] in normal and leukemic progenitor cells. Ann N Y Acad Sci (1988) 0.76
Glucocorticoid uncoupling of antiogensin II-dependent phospholipase C activation in rat vascular smooth muscle cells. Kidney Int (1994) 0.76
Thapsigargin suppresses phorbol ester-dependent human involucrin promoter activity by suppressing CCAAT-enhancer-binding protein alpha (C/EBPalpha) DNA binding. Biochem J (2000) 0.75
Influencing career choice during residency. J Gen Intern Med (1999) 0.75
Guanosine 5'-[gamma-thio]triphosphate induces membrane localization of cytosol-independent phospholipase D activity in a cell-free system from U937 promonocytic leucocytes. Biochem J (1994) 0.75
Renal sugar transport in the winter flounder. III. Two glucose transport systems. Am J Physiol (1977) 0.75
Assessing and changing unprofessional behaviors among faculty, residents, and students. Acad Med (2000) 0.75
Renal sugar transport in the winter flounder. IV. Effect of Ca2+ on sugar transport in teased renal tubules. J Cell Physiol (1977) 0.75
Regulation of cytosolic pH of cultured mesangial cells by prostaglandin F2 alpha and thromboxane A2. Am J Physiol (1991) 0.75
Resident and faculty perceptions of continuity practice experience in two teaching models. Acad Med (1999) 0.75
Stimulation of cytosolic free calcium and contraction by immune complexes in cultured rat mesangial cells. Trans Assoc Am Physicians (1987) 0.75
Endothelin A receptor antagonism by PD 156707 does not reduce infarct size after coronary artery occlusion/reperfusion in pigs. J Pharmacol Exp Ther (1996) 0.75
Reversible modulation of erythrocyte Ca2+ homeostasis: a possible role for dialyzable plasma factors derived from patients with end-stage renal disease. J Lab Clin Med (1989) 0.75
Renal sugar transport in the winter flounder. II. Galactose transport system. Am J Physiol (1976) 0.75
Long-term suppression of the cerebral spread of a memory: effects of idazoxan and clonidine. Pharmacol Biochem Behav (1989) 0.75
Truncated analogues of endothelin and sarafotoxin are selective for the ETB receptor subtype. Pept Res (1994) 0.75