Published in J Immunol on August 15, 2001
P2X7 receptor-Pannexin1 complex: pharmacology and signaling. Am J Physiol Cell Physiol (2008) 2.49
Activation and regulation of purinergic P2X receptor channels. Pharmacol Rev (2011) 2.14
Acid sphingomyelinase activity triggers microparticle release from glial cells. EMBO J (2009) 1.78
Discovery of P2X7 receptor-selective antagonists offers new insights into P2X7 receptor function and indicates a role in chronic pain states. Br J Pharmacol (2007) 1.77
Caspase-11 Requires the Pannexin-1 Channel and the Purinergic P2X7 Pore to Mediate Pyroptosis and Endotoxic Shock. Immunity (2015) 1.61
P2 receptors: intracellular signaling. Pflugers Arch (2006) 1.48
Mammalian P2X7 receptor pharmacology: comparison of recombinant mouse, rat and human P2X7 receptors. Br J Pharmacol (2009) 1.39
Molecular and functional properties of P2X receptors--recent progress and persisting challenges. Purinergic Signal (2012) 1.31
Allosteric modulation of ATP-gated P2X receptor channels. Rev Neurosci (2011) 1.16
P2X(7) receptor: Death or life? Purinergic Signal (2005) 1.13
Microglial microvesicle secretion and intercellular signaling. Front Physiol (2012) 1.12
The human cathelicidin LL-37 modulates the activities of the P2X7 receptor in a structure-dependent manner. J Biol Chem (2008) 1.08
Activation of ERK1/2 by extracellular nucleotides in macrophages is mediated by multiple P2 receptors independently of P2X7-associated pore or channel formation. Br J Pharmacol (2006) 1.08
Nucleotide receptor signaling in murine macrophages is linked to reactive oxygen species generation. Free Radic Biol Med (2007) 1.05
Critical involvement of extracellular ATP acting on P2RX7 purinergic receptors in photoreceptor cell death. Am J Pathol (2011) 1.02
Transcriptional control mechanisms associated with the nucleotide receptor P2X7, a critical regulator of immunologic, osteogenic, and neurologic functions. Immunol Res (2011) 0.99
Inhibition of P2X(7) receptors by divalent cations: old action and new insight. Eur Biophys J (2008) 0.93
P2X(7) nucleotide receptors mediate caspase-8/9/3-dependent apoptosis in rat primary cortical neurons. Purinergic Signal (2005) 0.91
Cell signaling via the P2X(7) nucleotide receptor: linkage to ROS production, gene transcription, and receptor trafficking. Purinergic Signal (2009) 0.91
Nucleotide receptor signalling and the generation of reactive oxygen species. Purinergic Signal (2007) 0.89
The trafficking and targeting of P2X receptors. Front Cell Neurosci (2013) 0.89
C terminus of the P2X7 receptor: treasure hunting. Purinergic Signal (2011) 0.89
Synergic effects of mycoplasmal lipopeptides and extracellular ATP on activation of macrophages. Infect Immun (2002) 0.86
Interaction of P2 purinergic receptors with cellular macromolecules. Naunyn Schmiedebergs Arch Pharmacol (2007) 0.86
Involvement of purinergic signalling in central mechanisms of body temperature regulation in rats. Br J Pharmacol (2002) 0.85
Deletion of P2X7 attenuates hyperoxia-induced acute lung injury via inflammasome suppression. Am J Physiol Lung Cell Mol Physiol (2016) 0.84
The role of P2 receptors in controlling infections by intracellular pathogens. Purinergic Signal (2007) 0.84
P2X7 receptor activation contributes to an initial upstream mechanism of lipopolysaccharide-induced vascular dysfunction. Clin Sci (Lond) (2013) 0.84
Lipopolysaccharide Induces Alveolar Macrophage Necrosis via CD14 and the P2X7 Receptor Leading to Interleukin-1α Release. Immunity (2015) 0.84
E-NTPDases in human airways: Regulation and relevance for chronic lung diseases. Purinergic Signal (2006) 0.83
P2X(7) receptor at the heart of disease. Hippokratia (2010) 0.79
Lipid metabolism modulation by the P2X7 receptor in the immune system and during the course of infection: new insights into the old view. Purinergic Signal (2011) 0.79
Lack of association of P2RX7 gene rs2230912 polymorphism with mood disorders: a meta-analysis. PLoS One (2014) 0.78
Exploiting powder X-ray diffraction for direct structure determination in structural biology: the P2X4 receptor trafficking motif YEQGL. J Struct Biol (2011) 0.78
Synthesis and structure-activity relationship studies of tyrosine-based antagonists at the human P2X7 receptor. Bioorg Med Chem Lett (2007) 0.78
Molecular characterization and expression analysis of ATP-gated P2X7 receptor involved in Japanese flounder (Paralichthys olivaceus) innate immune response. PLoS One (2014) 0.77
Lipopolysaccharide inhibits the channel activity of the P2X7 receptor. Mediators Inflamm (2011) 0.77
Structural and molecular modeling features of P2X receptors. Int J Mol Sci (2014) 0.76
P2X7R activation drives distinct IL-1 responses in dendritic cells compared to macrophages. Cytokine (2015) 0.76
XB130: A novel adaptor protein in cancer signal transduction. Biomed Rep (2016) 0.75
The C-terminus of human nucleotide receptor P2X7 is critical for receptor oligomerization and N-linked glycosylation. PLoS One (2013) 0.75
Purinergic Signaling in Corneal Wound Healing: A Tale of 2 Receptors. J Ocul Pharmacol Ther (2016) 0.75
The role of P2X7 receptors in tissue fibrosis: a brief review. Purinergic Signal (2015) 0.75
The P2X7 receptor forms a dye-permeable pore independent of its intracellular domain but dependent on membrane lipid composition. Elife (2017) 0.75
Searching Novel Therapeutic Targets for Scleroderma: P2X7-Receptor Is Up-regulated and Promotes a Fibrogenic Phenotype in Systemic Sclerosis Fibroblasts. Front Pharmacol (2017) 0.75
Inhibition of Toll-Like Receptor Signaling as a Promising Therapy for Inflammatory Diseases: A Journey from Molecular to Nano Therapeutics. Front Physiol (2017) 0.75
Binding and factor XIIIa-mediated cross-linking of a 27-kilodalton fragment of fibronectin to Staphylococcus aureus. Science (1980) 3.68
Persistent infection with small colony variant strains of Staphylococcus aureus in patients with cystic fibrosis. J Infect Dis (1998) 3.61
ATP-dependent inositide phosphorylation required for Ca(2+)-activated secretion. Nature (1995) 3.30
A site-directed Staphylococcus aureus hemB mutant is a small-colony variant which persists intracellularly. J Bacteriol (1997) 3.25
Gentamicin-resistant menadione and hemin auxotrophic Staphylococcus aureus persist within cultured endothelial cells. J Infect Dis (1994) 2.91
Recovery of small colony variants of Staphylococcus aureus following gentamicin bead placement for osteomyelitis. Clin Infect Dis (1997) 2.82
Fibronectin binding to Staphylococcus aureus. J Biol Chem (1982) 2.54
Identification, cloning, and initial characterization of rot, a locus encoding a regulator of virulence factor expression in Staphylococcus aureus. J Bacteriol (2000) 2.52
Reduced adherence to traumatized rat heart valves by a low-fibronectin-binding mutant of Staphylococcus aureus. Infect Immun (1989) 2.36
Endothelin stimulates phospholipase C, Na+/H+ exchange, c-fos expression, and mitogenesis in rat mesangial cells. J Clin Invest (1989) 2.17
Type I phosphatidylinositol 4-phosphate 5-kinase isoforms are specifically stimulated by phosphatidic acid. J Biol Chem (1994) 2.14
Towards a revised nomenclature for P1 and P2 receptors. Trends Pharmacol Sci (1997) 2.09
Isoquinolines as antagonists of the P2X7 nucleotide receptor: high selectivity for the human versus rat receptor homologues. Mol Pharmacol (1998) 1.94
Detection of local ATP release from activated platelets using cell surface-attached firefly luciferase. Am J Physiol (1999) 1.94
Fibronectin mediates attachment of Staphylococcus aureus to human neutrophils. Blood (1982) 1.93
Phagocytosis of Staphylococcus aureus by cultured bovine aortic endothelial cells: model for postadherence events in endovascular infections. Infect Immun (1986) 1.93
Use of adhesion-defective mutants of Staphylococcus aureus to define the role of specific plasma proteins in promoting bacterial adhesion to canine arteriovenous shunts. Infect Immun (1995) 1.85
Immunoaffinity purification of the epidermal growth factor receptor. Stoichiometry of binding and kinetics of self-phosphorylation. J Biol Chem (1984) 1.80
Self-phosphorylation enhances the protein-tyrosine kinase activity of the epidermal growth factor receptor. J Biol Chem (1985) 1.80
Inhibition of Jack Bean urease (EC 3.5.1.5) by acetohydroxamic acid and by phosphoramidate. An equivalent weight for urease. J Am Chem Soc (1975) 1.79
Staphylocidal action of thrombin-induced platelet microbicidal protein is not solely dependent on transmembrane potential. Infect Immun (1996) 1.79
The insulin-mimetic effects of vanadate in isolated rat adipocytes. Dissociation from effects of vanadate as a (Na+-K+)ATPase inhibitor. J Biol Chem (1980) 1.71
Ingestion of Staphylococcus aureus by bovine endothelial cells results in time- and inoculum-dependent damage to endothelial cell monolayers. Infect Immun (1987) 1.55
Intracellular Ca2+ mobilization activated by extracellular ATP in Ehrlich ascites tumor cells. J Biol Chem (1985) 1.53
Estrogen rapidly induces the phosphorylation of the cAMP response element binding protein in rat brain. Endocrinology (1996) 1.50
Cytotoxic effects of ingested Staphylococcus aureus on bovine endothelial cells: role of S. aureus alpha-hemolysin. Microb Pathog (1988) 1.46
Phagocytosis of Francisella tularensis by Rhesus monkey peripheral leukocytes. Infect Immun (1975) 1.46
Fibronectin-induced agglutination of Staphylococcus aureus correlates with invasiveness. J Lab Clin Med (1984) 1.46
Modulation of P2X7 nucleotide receptor expression by pro- and anti-inflammatory stimuli in THP-1 monocytes. J Leukoc Biol (1998) 1.45
Maitotoxin and P2Z/P2X(7) purinergic receptor stimulation activate a common cytolytic pore. Am J Physiol (1999) 1.44
Decreased susceptibility to antibiotic killing of a stable small colony variant of Staphylococcus aureus in fluid phase and on fibronectin-coated surfaces. J Antimicrob Chemother (1997) 1.44
Staphylococcus aureus small colony variants are induced by the endothelial cell intracellular milieu. J Infect Dis (1996) 1.43
Protection of mice against lethal endotoxemia by a lipid A precursor. Infect Immun (1986) 1.42
Different calcium dependence of the capping and cutting activities of villin. J Biol Chem (1986) 1.41
Induction of the P2z/P2X7 nucleotide receptor and associated phospholipase D activity by lipopolysaccharide and IFN-gamma in the human THP-1 monocytic cell line. J Immunol (1996) 1.41
Bloodstream infections caused by small-colony variants of coagulase-negative staphylococci following pacemaker implantation. Clin Infect Dis (1999) 1.39
Calcium is a key signaling molecule in beta-lapachone-mediated cell death. J Biol Chem (2001) 1.39
Coagulase-negative staphylococci. Pathogens have major role in nosocomial infections. Postgrad Med (2001) 1.38
Marek's disease virus (MDV) encodes an interleukin-8 homolog (vIL-8): characterization of the vIL-8 protein and a vIL-8 deletion mutant MDV. J Virol (2001) 1.34
Fibronectin is more active than fibrin or fibrinogen in promoting Staphylococcus aureus adherence to inserted intravascular catheters. J Infect Dis (1993) 1.34
Adhesion of Staphylococcus aureus to surface-bound platelets: role of fibrinogen/fibrin and platelet integrins. J Infect Dis (1993) 1.34
Endotoxin in vitro interactions with human neutrophils: depression of chemiluminescence, oxygen consumption, superoxide production, and killing. Infect Immun (1979) 1.32
Elicitation of peritoneal polymorphonuclear neutrophils from mice. J Immunol Methods (1982) 1.32
Staphylococcus aureus small colony variants, electron transport and persistent infections. Int J Antimicrob Agents (2000) 1.31
Extracellular ATP activates polyphosphoinositide breakdown and Ca2+ mobilization in Ehrlich ascites tumor cells. Arch Biochem Biophys (1986) 1.30
Stress-activated protein kinase/JNK activation and apoptotic induction by the macrophage P2X7 nucleotide receptor. J Biol Chem (2000) 1.28
Regulation of P2X(7) nucleotide receptor function in human monocytes by extracellular ions and receptor density. Am J Physiol Cell Physiol (2001) 1.28
Mitogenic signals for platelet-derived growth factor isoforms in liver fat-storing cells. Am J Physiol (1991) 1.24
Differential activation of cation channels and non-selective pores by macrophage P2z purinergic receptors expressed in Xenopus oocytes. J Biol Chem (1994) 1.23
Where does a Staphylococcus aureus vaccine stand? Clin Microbiol Infect (2014) 1.18
Purinergic receptor modulation of lipopolysaccharide signaling and inducible nitric-oxide synthase expression in RAW 264.7 macrophages. J Biol Chem (1998) 1.17
Biological and clinical effects of intravenous tumor necrosis factor-alpha administered three times weekly. Cancer Res (1991) 1.16
Stage-specific expression of P2Y receptors, ecto-apyrase, and ecto-5'-nucleotidase in myeloid leukocytes. Am J Physiol (1997) 1.16
Effects of subinhibitory concentrations of antibiotics on Staphylococcus aureus interactions with fibronectin. J Antimicrob Chemother (1983) 1.16
A novel pathway for the activation of phospholipase D by P2z purinergic receptors in BAC1.2F5 macrophages. J Biol Chem (1992) 1.14
Human monocytic cells direct the robust release of CXCL10 by bronchial epithelial cells during rhinovirus infection. Clin Exp Allergy (2010) 1.14
Extracellular adenosine triphosphate activates calcium mobilization in human phagocytic leukocytes and neutrophil/monocyte progenitor cells. J Clin Invest (1989) 1.14
Regulation of inducible nitric oxide synthase expression by macrophage purinoreceptors and calcium. J Biol Chem (1996) 1.12
A phosphatidylinositol 4,5-bisphosphate-sensitive casein kinase I alpha associates with synaptic vesicles and phosphorylates a subset of vesicle proteins. J Cell Biol (1995) 1.11
Estrogen modulation of prolactin gene expression requires an intact mitogen-activated protein kinase signal transduction pathway in cultured rat pituitary cells. Mol Endocrinol (2000) 1.10
Lipid X ameliorates pulmonary hypertension and protects sheep from death due to endotoxin. Infect Immun (1987) 1.09
Blastomycosis is a serious disease, but let's not raise fears without conclusive data. WMJ (2001) 1.07
ERK1 and ERK2 activation by chemotactic factors in human eosinophils is interleukin 5-dependent and contributes to leukotriene C(4) biosynthesis. J Biol Chem (2000) 1.06
Integrin-mediated migration of murine B82L fibroblasts is dependent on the expression of an intact epidermal growth factor receptor. J Biol Chem (1999) 1.06
Quantitative comparison of clumping factor- and coagulase-mediated Staphylococcus aureus adhesion to surface-bound fibrinogen under flow. Infect Immun (1995) 1.06
Role of fibronectin in human monocyte and macrophage bactericidal activity. Infect Immun (1985) 1.05
Role of host and bacterial factors in modulating staphylococcal adhesion to implanted polymer surfaces. J Biomater Appl (1990) 1.05
Epidermal growth factor and its receptor. Mol Cell Endocrinol (1987) 1.04
Immunohistochemical evidence for ATP receptors in human dental pulp. J Dent Res (2001) 1.04
Toward an understanding of biomaterial infections: a complex interplay between the host and bacteria. J Lab Clin Med (2000) 1.04
Subinhibitory concentrations of antibiotics alter fibronectin binding to Staphylococcus aureus. Antimicrob Agents Chemother (1983) 1.04
Agonist-induced calcium transients in cultured smooth muscle cells: measurements with fura-2 loaded monolayers. Biochem Biophys Res Commun (1986) 1.04
Immunoelectron microscopic localization of fibronectin in adherence of Staphylococcus aureus to cultured bovine endothelial cells. J Infect Dis (1989) 1.03
The P2X1 receptor, an adenosine triphosphate-gated cation channel, is expressed in human platelets but not in human blood leukocytes. Blood (1998) 1.03
Endotoxin activation of macrophages does not induce ATP release and autocrine stimulation of P2 nucleotide receptors. J Immunol (2000) 1.03
Effects of PDGF on inositol phosphates, Ca2+, and contraction of mesangial cells. Am J Physiol (1987) 1.02
Phosphorylation of protein 4.1 on tyrosine-418 modulates its function in vitro. Proc Natl Acad Sci U S A (1991) 1.00
Activation and inhibition of Limulus amebocyte lysate coagulation by chemically defined substructures of lipid A. Infect Immun (1985) 1.00
Epidermal growth factor-stimulated tyrosine phosphorylation of caveolin-1. Enhanced caveolin-1 tyrosine phosphorylation following aberrant epidermal growth factor receptor status. J Biol Chem (2000) 1.00
Host defences and the vaginal mucosa. A re-evaluation. Scand J Urol Nephrol Suppl (1984) 1.00
Growth hormone stimulates the tyrosine phosphorylation of 42- and 45-kDa ERK-related proteins. J Biol Chem (1992) 1.00
Kinetics of phosphorylation of Na+/K(+)-ATPase by protein kinase C. Biochim Biophys Acta (1990) 1.00
A three-step purification procedure for protein kinase C: characterization of the purified enzyme. Anal Biochem (1987) 1.00
Platelet-derived growth factor-stimulated migration of murine fibroblasts is associated with epidermal growth factor receptor expression and tyrosine phosphorylation. J Biol Chem (2000) 0.99
Transmodulation of epidermal growth factor receptor function by cyclic AMP-dependent protein kinase. J Biol Chem (1999) 0.98
Left ventricular assist device infection is associated with increased mortality but is not a contraindication to transplantation. Circulation (1997) 0.97
Regional distribution of cytosolic and particulate 5alpha-dihydroprogesterone 3alpha-hydroxysteroid oxidoreductases in female rat brain. J Steroid Biochem Mol Biol (1997) 0.96
Genetic differences in oxygen toxicity are correlated with cytochrome P-450 inducibility. Proc Natl Acad Sci U S A (1985) 0.96
Segmental allergen challenge enhances chitinase activity and levels of CCL18 in mild atopic asthma. Clin Exp Allergy (2013) 0.96
Phosphorus-31 nuclear magnetic resonance studies of single muscle cells isolated from barnacle depressor muscle. Biochemistry (1983) 0.96
The juxtamembrane, cytosolic region of the epidermal growth factor receptor is involved in association with alpha-subunit of Gs. J Biol Chem (1997) 0.95
Guanine-nucleotide- and adenine-nucleotide-dependent regulation of phospholipase D in electropermeabilized HL-60 granulocytes. Biochem J (1991) 0.95
Lipid X protects mice against fatal Escherichia coli infection. Infect Immun (1988) 0.95
Immunostimulatory, but not antiendotoxin, activity of lipid X is due to small amounts of contaminating N,O-acylated disaccharide-1-phosphate: in vitro and in vivo reevaluation of the biological activity of synthetic lipid X. Infect Immun (1991) 0.95
Bacterial colonization of functionalized polyurethanes. Biomaterials (2000) 0.94