Published in J Immunol on June 01, 1987
Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med (1989) 15.15
Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets. J Exp Med (1989) 11.36
Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens. J Exp Med (1988) 7.02
Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc Natl Acad Sci U S A (1992) 6.37
The central role of CD4(+) T cells in the antitumor immune response. J Exp Med (1998) 6.02
Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system. Proc Natl Acad Sci U S A (1992) 5.55
Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI. Proc Natl Acad Sci U S A (1991) 5.02
Induction of nonspecific acquired resistance and delayed-type hypersensitivity, but not specific acquired resistance in mice inoculated with killed mycobacterial vaccines. Infect Immun (1988) 3.79
Induction of airway mucus production By T helper 2 (Th2) cells: a critical role for interleukin 4 in cell recruitment but not mucus production. J Exp Med (1997) 3.33
Lymphokine-mediated regulation of the proliferative response of clones of T helper 1 and T helper 2 cells. J Exp Med (1988) 3.16
Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology. J Exp Med (1994) 2.99
Altered peptide ligands can control CD4 T lymphocyte differentiation in vivo. J Exp Med (1995) 2.80
Influenza virus-specific CD4+ T helper type 2 T lymphocytes do not promote recovery from experimental virus infection. J Exp Med (1994) 2.53
Tumor necrosis factor is a critical mediator in hapten induced irritant and contact hypersensitivity reactions. J Exp Med (1991) 2.24
Th2 cells and GATA-3 in asthma: new insights into the regulation of airway inflammation. J Clin Invest (1999) 2.03
Patterns of cytokine production by mycobacterium-reactive human T-cell clones. Infect Immun (1993) 1.72
Interleukin 10 but not interleukin 4 is a natural suppressant of cutaneous inflammatory responses. J Exp Med (1995) 1.68
A mannoprotein constituent of Candida albicans that elicits different levels of delayed-type hypersensitivity, cytokine production, and anticandidal protection in mice. Infect Immun (1994) 1.68
Murine CD4+ T cell subsets defined. J Exp Med (1988) 1.62
"Anergy" of TH0 helper T lymphocytes induces downregulation of TH1 characteristics and a transition to a TH2-like phenotype. J Exp Med (1994) 1.60
Characterization of cellular infiltrates and cytokine production during the expression phase of the anticryptococcal delayed-type hypersensitivity response. Infect Immun (1993) 1.57
A common factor regulates both Th1- and Th2-specific cytokine gene expression. EMBO J (1994) 1.56
Role of L3T4+ lymphocytes in protective immunity to systemic Candida albicans infection in mice. Infect Immun (1989) 1.56
Low-affinity IgE receptor (CD23) function on mouse B cells: role in IgE-dependent antigen focusing. Proc Natl Acad Sci U S A (1989) 1.49
Specific killing of cytotoxic T cells and antigen-presenting cells by CD4+ cytotoxic T cell clones. A novel potentially immunoregulatory T-T cell interaction in man. J Exp Med (1990) 1.48
MHC control of CD4+ T cell subset activation. J Exp Med (1989) 1.45
Interleukin 13 is a B cell stimulating factor. J Exp Med (1994) 1.41
Coexpression of granulocyte-macrophage colony-stimulating factor, gamma interferon, and interleukins 3 and 4 is random in murine alloreactive T-lymphocyte clones. Proc Natl Acad Sci U S A (1988) 1.41
Protective role of gamma interferon in experimental pulmonary paracoccidioidomycosis. Infect Immun (1998) 1.38
Cytokine responses during mycobacterial and schistosomal antigen-induced pulmonary granuloma formation. Production of Th1 and Th2 cytokines and relative contribution of tumor necrosis factor. Am J Pathol (1994) 1.35
Influence of pathological progression on the balance between cellular and humoral immune responses in bovine tuberculosis. Immunology (2005) 1.34
Targeting the IL-15 receptor with an antagonist IL-15 mutant/Fc gamma2a protein blocks delayed-type hypersensitivity. J Immunol (1998) 1.32
T-cell-mediated clearance of mouse hepatitis virus strain JHM from the central nervous system. J Virol (1989) 1.27
Cytotoxicity is mandatory for CD8(+) T cell-mediated contact hypersensitivity. J Exp Med (1999) 1.26
Vaccination with recombinant vaccinia viruses expressing ICP27 induces protective immunity against herpes simplex virus through CD4+ Th1+ T cells. J Virol (1995) 1.25
Adequate expression of protective immunity in the absence of granuloma formation in Mycobacterium tuberculosis-infected mice with a disruption in the intracellular adhesion molecule 1 gene. Infect Immun (1998) 1.22
Dissociated development of T cells mediating delayed-type hypersensitivity and protective T cells against Listeria monocytogenes and their functional difference in lymphokine production. Infect Immun (1991) 1.21
Cytokine profiles associated with induction of the anticryptococcal cell-mediated immune response. Infect Immun (1993) 1.19
Mucosal tolerance to E-selectin provides cell-mediated protection against ischemic brain injury. Proc Natl Acad Sci U S A (2003) 1.18
Immunohistological analysis of T cell functional subsets in chronic inflammatory periodontal disease. Clin Exp Immunol (1995) 1.17
Mucosal priming of T-lymphocyte responses to fed protein antigens using cholera toxin as an adjuvant. Immunology (1991) 1.15
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Immunity to Trichinella spiralis infection in vitamin A-deficient mice. J Exp Med (1992) 1.13
Detection of cytokines at the site of tuberculin-induced delayed-type hypersensitivity in man. Clin Exp Immunol (1992) 1.13
Primary human T-cell responses to the major outer membrane protein of Chlamydia trachomatis. Immunology (1993) 1.13
Cytokines. 3. Cytokines in asthma. Thorax (1993) 1.12
Prenatal immune challenge alters the hypothalamic-pituitary-adrenocortical axis in adult rats. J Clin Invest (1994) 1.11
Generation of rat Th2-like cells in vitro is interleukin-4-dependent and inhibited by interferon-gamma. Immunology (1993) 1.10
Systemic immunological effects of cytokine genes injected into skeletal muscle. Proc Natl Acad Sci U S A (1993) 1.10
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Characterization of T cells and cytokines in the aqueous humour (AH) in patients with Fuchs' heterochromic cyclitis (FHC) and idiopathic anterior uveitis (IAU). Clin Exp Immunol (1998) 1.09
Role of tumour necrosis factor-alpha in ultraviolet B light-induced dendritic cell migration and suppression of contact hypersensitivity. Immunology (1994) 1.09
Evidence for mouse Th1- and Th2-like helper T cells in vivo. Selective reduction of Th1-like cells after total lymphoid irradiation. J Exp Med (1989) 1.09
Deletion of IL-4Ralpha on CD4 T cells renders BALB/c mice resistant to Leishmania major infection. PLoS Pathog (2007) 1.09
Successive tick infestations selectively promote a T-helper 2 cytokine profile in mice. Immunology (1999) 1.08
Interleukin-1-induced promotion of T-cell differentiation in mice immunized with killed Listeria monocytogenes. Infect Immun (1990) 1.06
Dynamic analysis of splenic Th1 and Th2 lymphocyte functions in mice infected with Schistosoma japonicum. Infect Immun (1991) 1.05
Chitosan nanoparticles act as an adjuvant to promote both Th1 and Th2 immune responses induced by ovalbumin in mice. Mar Drugs (2011) 1.04
Effect of adoptive transfer of cloned Actinobacillus actinomycetemcomitans-specific T helper cells on periodontal disease. Infect Immun (1991) 1.02
Differential stimulation of immune function by respiratory and contact chemical allergens. Immunology (1991) 1.01
Short-term starvation of immune deficient Drosophila improves survival to gram-negative bacterial infections. PLoS One (2009) 1.00
Effects of virally expressed interleukin-10 on vaccinia virus infection in mice. J Virol (1993) 1.00
Low zone tolerance to contact allergens in mice: a functional role for CD8+ T helper type 2 cells. J Exp Med (1996) 1.00
Three protein cocktails mediate delayed-type hypersensitivity responses indistinguishable from that elicited by purified protein derivative in the guinea pig model of Mycobacterium tuberculosis infection. Infect Immun (2010) 1.00
In vitro effects of interleukin-4 on interferon-gamma-induced macrophage activation. Immunology (1992) 0.99
Characterization of phenotype and cytokine profiles of T cell lines derived from vitreous humour in ocular inflammation in man. Clin Exp Immunol (1999) 0.99
Expression of the murine interleukin-4 gene in an attenuated aroA strain of Salmonella typhimurium: persistence and immune response in BALB/c mice and susceptibility to macrophage killing. Infect Immun (1993) 0.98
Role of CD44 in the differentiation of Th1 and Th2 cells: CD44-deficiency enhances the development of Th2 effectors in response to sheep RBC and chicken ovalbumin. J Immunol (2009) 0.97
Different migration patterns of antigen-presenting cells correlate with Th1/Th2-type responses in mice. Immunology (1995) 0.97
Characterization of Bartonella henselae-specific immunity in BALB/c mice. Immunology (1999) 0.96
Priming of systemic and local delayed-type hypersensitivity responses by feeding low doses of ovalbumin to mice. Immunology (1989) 0.96
Interleukin-4 is a critical cytokine in contact sensitivity. Immunology (1995) 0.96
Murine T-cell response to native and recombinant protein antigens of Rickettsia tsutsugamushi. Infect Immun (1993) 0.96
Functional heterogeneity of L3T4+ T cells in MRL-lpr/lpr mice. L3T4+ T cells suppress major histocompatibility complex-self-restricted L3T4+ T helper cell function in association with autoimmunity. J Exp Med (1988) 0.95
Schistosomiasis. Infection versus disease and hypersensitivity versus immunity. Am J Pathol (1993) 0.95
Early delayed-type hypersensitivity eosinophil infiltrates depend on T helper 2 cytokines and interferon-gamma via CXCR3 chemokines. Immunology (2004) 0.93
Novel role of CD8(+) T cells and major histocompatibility complex class I genes in the generation of protective CD4(+) Th1 responses during retrovirus infection in mice. J Virol (2002) 0.93
Regulatory mechanisms of helper T cell differentiation: new lessons learned from interleukin 17 family cytokines. Pharmacol Ther (2008) 0.93
Skin test to assess virus-specific cytotoxic T-cell activity. Proc Natl Acad Sci U S A (1992) 0.93
Contribution of CD4+ and CD8+ T lymphocyte subsets to the cytokine secretion patterns induced in mice during sensitization to contact and respiratory chemical allergens. Immunology (1996) 0.92
Role of CD4(+) T helper 2-type cells in cutaneous inflammatory responses induced by fluorescein isothiocyanate. Immunology (2000) 0.92
Leptin deficiency impairs maturation of dendritic cells and enhances induction of regulatory T and Th17 cells. Eur J Immunol (2014) 0.91
Up-regulation of alveolar macrophage platelet-derived growth factor-B (PDGF-B) mRNA by interferon-gamma from Mycobacterium tuberculosis antigen (PPD)-stimulated lymphocytes. Clin Exp Immunol (1993) 0.91
Liposomal encapsulation enhances and prolongs the anti-inflammatory effects of water-soluble dexamethasone phosphate in experimental adjuvant arthritis. Arthritis Res Ther (2010) 0.91
Profound atrophy of the bone marrow reflecting major histocompatibility complex class II-restricted destruction of stem cells by CD4+ cells. J Exp Med (1994) 0.90
A sequential study of the bovine tuberculin reaction. Immunology (1996) 0.90
Establishment and functional characterization of human herpesvirus 6-specific CD4+ human T-cell clones. J Virol (1992) 0.89
The role of the T follicular helper cells in allergic disease. Cell Mol Immunol (2012) 0.89
Modulation of a heterologous immune response by the products of Ascaris suum. Infect Immun (2002) 0.89
The in vivo mechanism of action of CTLA4Ig. J Immunol (1996) 0.89
Transforming growth factor-beta/Smad3 signalling regulates inflammatory responses in a murine model of contact hypersensitivity. Br J Dermatol (2008) 0.88
Barrier immunity and IL-17. Semin Immunol (2009) 0.88
Dietary flavones suppresses IgE and Th2 cytokines in OVA-immunized BALB/c mice. Eur J Nutr (2007) 0.88
The adjuvant activity of non-ionic surfactant vesicles (niosomes) on the BALB/c humoral response to bovine serum albumin. Immunology (1992) 0.88
Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol (1986) 35.41
Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med (1989) 15.15
IL-10 inhibits cytokine production by activated macrophages. J Immunol (1991) 13.13
IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells. J Immunol (1991) 11.04
Interleukin-10. Annu Rev Immunol (1993) 10.14
Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon? Immunol Today (1993) 8.00
Lymphokine control of in vivo immunoglobulin isotype selection. Annu Rev Immunol (1990) 7.93
Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI. Science (1990) 7.18
Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells. Nature (1988) 5.56
IFN-gamma regulates the isotypes of Ig secreted during in vivo humoral immune responses. J Immunol (1988) 5.12
Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI. Proc Natl Acad Sci U S A (1991) 5.02
The characterization of four monoclonal antibodies specific for mouse IL-5 and development of mouse and human IL-5 enzyme-linked immunosorbent. J Immunol (1988) 4.38
Interleukin 10, a novel B cell stimulatory factor: unresponsiveness of X chromosome-linked immunodeficiency B cells. J Exp Med (1990) 4.30
Heterogeneity of mouse helper T cells. Evidence from bulk cultures and limiting dilution cloning for precursors of Th1 and Th2 cells. J Immunol (1990) 3.86
Expression of interleukin-10 activity by Epstein-Barr virus protein BCRF1. Science (1990) 3.70
T-cell and mast cell lines respond to B-cell stimulatory factor 1. Proc Natl Acad Sci U S A (1986) 3.56
Cytomegalovirus infectivity: analysis of the phenomenon of centrifugal enhancement of infectivity. Virology (1976) 3.44
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Cytokine-induced differentiation of precursor mouse CD8+ T cells into cytotoxic CD8+ T cells secreting Th1 or Th2 cytokines. Immunity (1995) 3.23
Lymphokine-mediated regulation of the proliferative response of clones of T helper 1 and T helper 2 cells. J Exp Med (1988) 3.16
IL-10, a novel growth cofactor for mature and immature T cells. J Immunol (1990) 3.02
Functional diversity of T lymphocytes due to secretion of different cytokine patterns. FASEB J (1991) 2.97
Synthesis of T helper 2-type cytokines at the maternal-fetal interface. J Immunol (1993) 2.65
The role of IFN-gamma in delayed-type hypersensitivity mediated by Th1 clones. J Immunol (1989) 2.40
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Polarized expression of cytokines in cell conjugates of helper T cells and splenic B cells. Proc Natl Acad Sci U S A (1991) 1.99
IL-10 inhibits cytokine production, vascular leakage, and swelling during T helper 1 cell-induced delayed-type hypersensitivity. J Immunol (1994) 1.96
Alloreactive murine CD8+ T cell clones secrete the Th1 pattern of cytokines. J Immunol (1990) 1.95
Single IL-2-secreting precursor CD4 T cell can develop into either Th1 or Th2 cytokine secretion phenotype. J Immunol (1994) 1.85
Murine T-cell clones specific for chicken erythrocyte alloantigens. Cell Immunol (1986) 1.77
Pregnancy impairs resistance of C57BL/6 mice to Leishmania major infection and causes decreased antigen-specific IFN-gamma response and increased production of T helper 2 cytokines. J Immunol (1996) 1.60
Effects of Th2 cytokines on chemokine expression in the lung: IL-13 potently induces eotaxin expression by airway epithelial cells. J Immunol (1999) 1.59
Species-specificity of T cell stimulating activities of IL 2 and BSF-1 (IL 4): comparison of normal and recombinant, mouse and human IL 2 and BSF-1 (IL 4). J Immunol (1987) 1.48
The effect of search procedures on utility elicitations. Med Decis Making (1998) 1.47
Use of meta-analytic results to facilitate shared decision making. J Am Med Inform Assoc (1999) 1.47
A mouse T cell product that preferentially enhances IgA production. I. Biologic characterization. J Immunol (1987) 1.44
Translation of lymphocyte mRNA into biologically-active Interleukin 2 in oocytes. J Immunol (1981) 1.33
A mouse T cell product that preferentially enhances IgA production. II. Physicochemical characterization. J Immunol (1987) 1.26
Modification and fate of J chain in myeloma cells in the presence and absence of polymeric immunoglobulin secretion. Eur J Immunol (1978) 1.26
Alterations in the amino-terminal third of mouse interleukin 2: effects on biological activity and immunoreactivity. J Immunol (1986) 1.21
Monoclonal antibodies showing sequence specificity in their interaction with single-stranded DNAs. Nucleic Acids Res (1981) 1.16
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