Published in J Exp Med on July 01, 1993
Bacterial superantigens induce T cell expression of the skin-selective homing receptor, the cutaneous lymphocyte-associated antigen, via stimulation of interleukin 12 production. J Exp Med (1995) 1.65
Allergen-stimulated interleukin-4 and interferon-gamma production in primary culture: responses of subjects with allergic rhinitis and normal controls. Immunology (1995) 0.98
Different migration patterns of antigen-presenting cells correlate with Th1/Th2-type responses in mice. Immunology (1995) 0.97
Anergy of antigen-specific T lymphocytes is a potent mechanism of intravenously induced tolerance. Immunology (1994) 0.94
T lymphocyte immunity in host defence against Chlamydia trachomatis and its implication for vaccine development. Can J Infect Dis (1998) 0.94
Systemic mycobacterial infection inhibits antigen-specific immunoglobulin E production, bronchial mucus production and eosinophilic inflammation induced by allergen. Immunology (1999) 0.88
Inducible interleukin-4-secreting cells provoked in mice during chemical sensitization. Immunology (1994) 0.87
Effect of recombinant human keratinocyte growth factor (rHuKGF) on the immunopathogenesis of intestinal graft-vs.-host disease induced without a preconditioning regimen. J Clin Immunol (2004) 0.87
Altering the cellular location of an antigen expressed by a DNA-based vaccine modulates the immune response. J Virol (1999) 0.86
Mycobacterial infection inhibits established allergic inflammatory responses via alteration of cytokine production and vascular cell adhesion molecule-1 expression. Immunology (2002) 0.86
A novel adjuvant-allergen complex, CBP-rFel d 1, induces up-regulation of CD86 expression and enhances cytokine release by human dendritic cells in vitro. Immunology (2004) 0.86
Reduced in vitro T-cell responses induced by glutaraldehyde-modified allergen extracts are caused mainly by retarded internalization of dendritic cells. Immunology (2012) 0.82
Different roles are played by alpha beta and gamma delta T cells in acquired immunity to Chlamydia trachomatis pulmonary infection. Immunology (1998) 0.81
Palifermin mediates immunoregulatory effects in addition to its cytoprotective effects in mice with acute graft-versus-host disease. J Clin Immunol (2008) 0.81
In vivo transcriptional regulation of the human immunodeficiency virus in the central nervous system in transgenic mice. J Virol (1996) 0.79
Vaccination with a multi-epitopic recombinant allergen induces specific immune deviation via T-cell anergy. Immunology (1997) 0.77
Graft-versus-host disease in recipients of grafts from natural killer T cell-deficient (Jalpha281(-/-)) donors. Immunology (2006) 0.77
Murine graft-versus-host disease induced using interferon-gamma-deficient grafts features antibodies to double-stranded DNA, T helper 2-type cytokines and hypereosinophilia. Immunology (2002) 0.77
Effect of palifermin in a murine model of graft-versus-host disease (GVHD) associated with Th2 cytokine production, autoantibody production, and glomerulonephritis. J Clin Immunol (2006) 0.76
Adjuvant effects of aluminium hydroxide-adsorbed allergens and allergoids - differences in vivo and in vitro. Clin Exp Immunol (2014) 0.76
Limiting dilution analysis of CD4 T-cell cytokine production in mice administered native versus polymerized ovalbumin: directed induction of T-helper type-1-like activation. Immunology (1996) 0.75
Lymphokine control of in vivo immunoglobulin isotype selection. Annu Rev Immunol (1990) 7.93
IL-4 directs the development of Th2-like helper effectors. J Immunol (1990) 7.20
Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells. J Exp Med (1990) 7.09
Differing lymphokine profiles of functional subsets of human CD4 and CD8 T cell clones. Science (1991) 6.12
Anti-proliferative effect of IFN-gamma in immune regulation. I. IFN-gamma inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones. J Immunol (1988) 5.80
IL-4 induces a Th2 response in Leishmania major-infected mice. J Immunol (1992) 4.43
Establishment of stable, cell-mediated immunity that makes "susceptible" mice resistant to Leishmania major. Science (1992) 3.59
Murine Th1 and Th2 clones proliferate optimally in response to distinct antigen-presenting cell populations. J Immunol (1991) 3.44
Role of T-cell derived cytokines in the downregulation of immune responses in parasitic and retroviral infection. Immunol Rev (1992) 3.30
Diversity of cytokine synthesis and function of mouse CD4+ T cells. Immunol Rev (1991) 2.49
Functional subsets of allergen-reactive human CD4+ T cells. Immunol Today (1991) 1.89
Aqueous antigens induce in vivo tolerance selectively in IL-2- and IFN-gamma-producing (Th1) cells. J Immunol (1992) 1.73
Preferential activation of Th2 cells in chronic graft-versus-host reaction. J Immunol (1993) 1.50
Immunoprotective Leishmania major synthetic T cell epitopes. J Exp Med (1990) 1.45
A repetitive peptide of Leishmania can activate T helper type 2 cells and enhance disease progression. J Exp Med (1990) 1.21
Anti-interferon gamma treatment blocks the ability of glutaraldehyde-polymerized allergens to inhibit specific IgE responses. J Exp Med (1991) 1.12
Polymerized ragweed antigen E. I. Preparation and immunologic studies. J Immunol (1973) 1.04
Glutaraldehyde-pollen-tyrosine: clinical and immunological studies. Clin Allergy (1974) 0.96
Long-lived reciprocal regulation of antigen-specific IgE and IgG2a responses in mice treated with glutaraldehyde-polymerized ovalbumin. Immunology (1991) 0.88
Conversion of nonimmunogenic low molecular weight ragweed components to immunogens for induction of homocytotropic antibody. Immunochemistry (1975) 0.87
Precocious induction of tyrosine aminotransferase mRNA by hydrocortisone in cultured fetal rat hepatocytes at different developmental stages. J Cell Physiol (1990) 0.80
Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol (1986) 35.41
Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med (1989) 15.15
IL-10 inhibits cytokine production by activated macrophages. J Immunol (1991) 13.13
IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells. J Immunol (1991) 11.04
Interleukin-10. Annu Rev Immunol (1993) 10.14
Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon? Immunol Today (1993) 8.00
Lymphokine control of in vivo immunoglobulin isotype selection. Annu Rev Immunol (1990) 7.93
Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI. Science (1990) 7.18
Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by TH1 clones. J Immunol (1987) 6.20
Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells. Nature (1988) 5.56
IFN-gamma regulates the isotypes of Ig secreted during in vivo humoral immune responses. J Immunol (1988) 5.12
Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI. Proc Natl Acad Sci U S A (1991) 5.02
The characterization of four monoclonal antibodies specific for mouse IL-5 and development of mouse and human IL-5 enzyme-linked immunosorbent. J Immunol (1988) 4.38
Interleukin 10, a novel B cell stimulatory factor: unresponsiveness of X chromosome-linked immunodeficiency B cells. J Exp Med (1990) 4.30
Heterogeneity of mouse helper T cells. Evidence from bulk cultures and limiting dilution cloning for precursors of Th1 and Th2 cells. J Immunol (1990) 3.86
Expression of interleukin-10 activity by Epstein-Barr virus protein BCRF1. Science (1990) 3.70
T-cell and mast cell lines respond to B-cell stimulatory factor 1. Proc Natl Acad Sci U S A (1986) 3.56
Cytomegalovirus infectivity: analysis of the phenomenon of centrifugal enhancement of infectivity. Virology (1976) 3.44
Interleukin 10: a novel stimulatory factor for mast cells and their progenitors. J Exp Med (1991) 3.34
Role of T-cell derived cytokines in the downregulation of immune responses in parasitic and retroviral infection. Immunol Rev (1992) 3.30
Cytokine-induced differentiation of precursor mouse CD8+ T cells into cytotoxic CD8+ T cells secreting Th1 or Th2 cytokines. Immunity (1995) 3.23
Lymphokine-mediated regulation of the proliferative response of clones of T helper 1 and T helper 2 cells. J Exp Med (1988) 3.16
IL-10, a novel growth cofactor for mature and immature T cells. J Immunol (1990) 3.02
Functional diversity of T lymphocytes due to secretion of different cytokine patterns. FASEB J (1991) 2.97
Synthesis of T helper 2-type cytokines at the maternal-fetal interface. J Immunol (1993) 2.65
Some properties of the genome of murine cytomegalovirus (MCV). Virology (1973) 2.40
The role of IFN-gamma in delayed-type hypersensitivity mediated by Th1 clones. J Immunol (1989) 2.40
Genetically determined differences in IL-10 and IFN-gamma responses correlate with clearance of Chlamydia trachomatis mouse pneumonitis infection. J Immunol (1996) 2.31
Polarized expression of cytokines in cell conjugates of helper T cells and splenic B cells. Proc Natl Acad Sci U S A (1991) 1.99
IL-10 inhibits cytokine production, vascular leakage, and swelling during T helper 1 cell-induced delayed-type hypersensitivity. J Immunol (1994) 1.96
Alloreactive murine CD8+ T cell clones secrete the Th1 pattern of cytokines. J Immunol (1990) 1.95
Single IL-2-secreting precursor CD4 T cell can develop into either Th1 or Th2 cytokine secretion phenotype. J Immunol (1994) 1.85
Murine T-cell clones specific for chicken erythrocyte alloantigens. Cell Immunol (1986) 1.77
Pregnancy impairs resistance of C57BL/6 mice to Leishmania major infection and causes decreased antigen-specific IFN-gamma response and increased production of T helper 2 cytokines. J Immunol (1996) 1.60
Effects of Th2 cytokines on chemokine expression in the lung: IL-13 potently induces eotaxin expression by airway epithelial cells. J Immunol (1999) 1.59
Species-specificity of T cell stimulating activities of IL 2 and BSF-1 (IL 4): comparison of normal and recombinant, mouse and human IL 2 and BSF-1 (IL 4). J Immunol (1987) 1.48
A mouse T cell product that preferentially enhances IgA production. I. Biologic characterization. J Immunol (1987) 1.44
Translation of lymphocyte mRNA into biologically-active Interleukin 2 in oocytes. J Immunol (1981) 1.33
A mouse T cell product that preferentially enhances IgA production. II. Physicochemical characterization. J Immunol (1987) 1.26
Modification and fate of J chain in myeloma cells in the presence and absence of polymeric immunoglobulin secretion. Eur J Immunol (1978) 1.26
Requirement for B cells in T cell priming to minor histocompatibility antigens and development of graft-versus-host disease. Bone Marrow Transplant (1995) 1.24
Murine graft-versus-host disease in an F1-hybrid model using IFN-gamma gene knockout donors. J Immunol (1998) 1.24
Comparison of [3H]thymidine incorporation with MTT- and MTS-based bioassays for human and murine IL-2 and IL-4 analysis. Tetrazolium assays provide markedly enhanced sensitivity. J Immunol Methods (1995) 1.22
Alterations in the amino-terminal third of mouse interleukin 2: effects on biological activity and immunoreactivity. J Immunol (1986) 1.21
Perforin and Fas killing by CD8+ T cells limits their cytokine synthesis and proliferation. J Exp Med (1996) 1.16
Monoclonal antibodies showing sequence specificity in their interaction with single-stranded DNAs. Nucleic Acids Res (1981) 1.16
The role of B cells for in vivo T cell responses to a Friend virus-induced leukemia. Science (1990) 1.13
Antigen-driven but not lipopolysaccharide-driven IL-12 production in macrophages requires triggering of CD40. J Immunol (1997) 1.12
Heat-killed Listeria monocytogenes as an adjuvant converts established murine Th2-dominated immune responses into Th1-dominated responses. J Immunol (1998) 1.12
Analysis of neonatal T cell and antigen presenting cell functions. Hum Immunol (1997) 1.11
Cytokine regulation of murine leishmaniasis: interleukin 4 is not sufficient to mediate progressive disease in resistant C57BL/6 mice. Infect Immun (1991) 1.08
A novel study design to investigate the early-life origins of asthma in children (SAGE study). Allergy (2009) 1.07
Infant gut microbiota and food sensitization: associations in the first year of life. Clin Exp Allergy (2015) 1.07
Structural mutations in a mouse immunoglobulin light chain resulting in failure to be secreted. Cell (1980) 1.06
Induction of antigen-specific antibody responses in primed and unprimed B cells. Functional heterogeneity among Th1 and Th2 T cell clones. J Immunol (1989) 1.06
CD8Tc1 and Tc2 cells secrete distinct cytokine patterns in vitro and in vivo but induce similar inflammatory reactions. J Immunol (1997) 1.06
Natural killer cell depletion fails to influence initial CD4 T cell commitment in vivo in exogenous antigen-stimulated cytokine and antibody responses. J Immunol (1998) 1.05
Mouse IL-13 enhances antibody production in vivo and acts directly on B cells in vitro to increase survival and hence antibody production. J Immunol (1999) 1.04
CD4+ T-cell subsets: regulation of differentiation and function. Res Immunol (1991) 1.02
Fel d 1 peptides: effect on skin tests and cytokine synthesis in cat-allergic human subjects. Int Immunol (1996) 0.99
T cell chemokine receptor expression in human Th1- and Th2-associated diseases. Arch Immunol Ther Exp (Warsz) (2000) 0.99
"Natural" antibodies to chicken MHC antigens are present in mice, rats, humans, alligators and allogeneic chickens. Immunogenetics (1980) 0.96
Allergen-dependent induction of interleukin-4 synthesis in vivo. Immunology (1993) 0.96
Cytokine-deficient CD8+ Tc1 cells induced by IL-4: retained inflammation and perforin and Fas cytotoxicity but compromised long term killing of tumor cells. J Immunol (1997) 0.94
Production and characterization of monoclonal antibodies to bovine skin proteodermatan sulfate. Coll Relat Res (1985) 0.94
Properties of the multicapsid virions of murine cytomegalovirus. Virology (1976) 0.94
Continuous administration of Il-13 to mice induces extramedullary hemopoiesis and monocytosis. J Immunol (1996) 0.94
Structural and functional heterogeneity of the murine cytomegalovirus genome. Virology (1974) 0.93
Mutations affecting immunoglobulin light chain secretion by myeloma cells. I. Functional analysis by cell fusion. Eur J Immunol (1979) 0.93
Effect of temperature on hybridoma cell cycle and MAb production. Biotechnol Bioeng (1992) 0.93
The ability of the murine placenta to absorb monoclonal anti-fetal H-2K antibody from the maternal circulation. J Immunol (1979) 0.93
A single antigen-specific B cell can conjugate to either a type 1 or a type 2 helper T cell. Proc Natl Acad Sci U S A (1988) 0.92
Specificity of autoimmune monoclonal Fab fragments binding to single-stranded deoxyribonucleic acid. Biochemistry (1982) 0.92
Pigmentation and acriflavine resistance in Serratia marcescens. J Bacteriol (1971) 0.92
Post-translational fate of variant MOPC 315 lambda chains in Xenopus oocytes and mouse myeloma cells. Eur J Biochem (1983) 0.89
Environmental antigen-induced IL-13 responses are elevated among subjects with allergic rhinitis, are independent of IL-4, and are inhibited by endogenous IFN-gamma synthesis. J Immunol (1998) 0.89
Long-lived reciprocal regulation of antigen-specific IgE and IgG2a responses in mice treated with glutaraldehyde-polymerized ovalbumin. Immunology (1991) 0.88
Allergen-specific modulation of cytokine synthesis patterns and IgE responses in vivo with chemically modified allergen. J Immunol (1993) 0.88
In vivo IL-12 administration induces profound but transient commitment to T helper cell type 1-associated patterns of cytokine and antibody production. J Immunol (1997) 0.87
Interleukin 10 modulates ion transport in rat small intestine. Gastroenterology (1996) 0.87
Elevated production of interferon-gamma and interleukin 4 by mature T cells from autoimmune lpr mice correlates with Pgp-1 (CD44) expression. Eur J Immunol (1991) 0.87
Primed and replicating but uncommitted T helper precursor cells show kinetics of differentiation and commitment similar to those of naive T helper cells. Microbes Infect (1999) 0.87
Structure and properties of the major histocompatibility complex of the chicken. Speculations on the advantages and evolution of polymorphism. Immunogenetics (1981) 0.87
Suppression of the IgE antibody response by glutaraldehyde-modified ovalbumin: dissociation between loss of antigenic reactivity and ability to induce suppression. Int Arch Allergy Appl Immunol (1984) 0.85
Nomenclature for chicken MHC (B) antigens defined by monoclonal antibodies. Immunogenetics (1981) 0.85
A simple, sensitive, dual mAb based ELISA for murine gamma interferon determination: comparison with two common bioassays. J Immunoassay (1993) 0.84
Cytotoxicity and weak CD40 ligand expression of CD8+ type 2 cytotoxic T cells restricts their potential B cell helper activity. Eur J Immunol (1997) 0.84
Improved mRNA quantitation in LightCycler RT-PCR. Int Arch Allergy Immunol (2003) 0.83
Antigen mediated and polyclonal stimulation of human cytokine production elicit qualitatively different patterns of cytokine gene expression. Int Immunol (1995) 0.83
Both CD4+ and CD8+ T-cells in syngeneic islet grafts in NOD mice produce interferon-gamma during beta-cell destruction. Diabetes (1996) 0.82
The Canadian healthy infant longitudinal development birth cohort study: biological samples and biobanking. Paediatr Perinat Epidemiol (2014) 0.82
Restricted expression of an MHC alloantigen in cells of the erythroid series: a specific marker for erythroid differentiation. J Supramol Struct (1980) 0.82
Suppressor T-cell factor(s) display an altered pattern of Igh (immunoglobulin heavy chain locus) genetic restriction when developed in an Igh-congeneic host. Proc Natl Acad Sci U S A (1985) 0.81
Comparison of chemiluminescent assays and colorimetric ELISAs for quantification of murine IL-12, human IL-4 and murine IL-4: chemiluminescent substrates provide markedly enhanced sensitivity. J Immunol Methods (2001) 0.81