Published in Mol Cell Biol on July 01, 1985
Structural alterations of the epidermal growth factor receptor gene in human gliomas. Proc Natl Acad Sci U S A (1992) 6.58
Transforming growth factor alpha may be a physiological regulator of liver regeneration by means of an autocrine mechanism. Proc Natl Acad Sci U S A (1989) 2.35
Establishment and characterization of differentiated, nontransformed hepatocyte cell lines derived from mice transgenic for transforming growth factor alpha. Proc Natl Acad Sci U S A (1994) 2.20
The Epstein-Barr virus latent membrane protein 1 induces expression of the epidermal growth factor receptor. J Virol (1995) 2.02
A truncated, secreted form of the epidermal growth factor receptor is encoded by an alternatively spliced transcript in normal rat tissue. Mol Cell Biol (1990) 1.90
Amplification of the structurally and functionally altered epidermal growth factor receptor gene (c-erbB) in human brain tumors. Mol Cell Biol (1988) 1.85
Epidermal growth factor receptor expression in neurofibromatosis type 1-related tumors and NF1 animal models. J Clin Invest (2000) 1.56
Polymorphisms, mutations, and amplification of the EGFR gene in non-small cell lung cancers. PLoS Med (2007) 1.52
Inhibition of tyrosine kinase activity of the epidermal growth factor (EGF) receptor by a truncated receptor form that binds to EGF: role for interreceptor interaction in kinase regulation. Mol Cell Biol (1989) 1.43
Epidermal growth factor regulates the expression of its own receptor. Proc Natl Acad Sci U S A (1985) 1.41
Epidermal growth factor receptor (EGFR) gene promoter methylation and cetuximab treatment in colorectal cancer patients. Br J Cancer (2011) 1.04
A 1.8 kb alternative transcript from the human epidermal growth factor receptor gene encodes a truncated form of the receptor. Nucleic Acids Res (1996) 1.03
Epidermal growth factor receptor gene-amplified MDA-468 breast cancer cell line and its nonamplified variants. Mol Cell Biol (1987) 1.01
Retrovirus-mediated transfer of an adenovirus gene encoding an integral membrane protein is sufficient to down regulate the receptor for epidermal growth factor. Mol Cell Biol (1990) 0.99
A two-stage case-control study of EGFR polymorphisms and breast cancer risk. Cancer Epidemiol Biomarkers Prev (2009) 0.96
An alternatively processed mRNA from the avian c-erbB gene encodes a soluble, truncated form of the receptor that can block ligand-dependent transformation. Mol Cell Biol (1992) 0.95
Genetic markers on chromosome 7. J Med Genet (1988) 0.95
Evidence for intracellular down-regulation of the epidermal growth factor (EGF) receptor during adenovirus infection by an EGF-independent mechanism. J Virol (1992) 0.92
Native avian c-erbB gene expresses a secreted protein product corresponding to the ligand-binding domain of the receptor. Proc Natl Acad Sci U S A (1991) 0.87
Epidermal growth factor receptor (EGFR) status and K-Ras mutations in colorectal cancer. Ann Oncol (2008) 0.84
Inhibition of epidermal growth factor receptor biosynthesis caused by the src oncogene product, pp60v-src. Mol Cell Biol (1990) 0.82
Epidermal growth factor receptor (EGFR) polymorphisms and breast cancer among Hispanic and non-Hispanic white women: the Breast Cancer Health Disparities Study. Int J Mol Epidemiol Genet (2013) 0.81
Soluble Epidermal Growth Factor Receptors (sEGFRs) in Cancer: Biological Aspects and Clinical Relevance. Int J Mol Sci (2016) 0.77
Correlations between EGFR gene polymorphisms and pleural metastasis of lung adenocarcinoma. Onco Targets Ther (2016) 0.75
A new HincII polymorphism at the epidermal growth factor receptor locus on chromosome 7. Nucleic Acids Res (1990) 0.75
A new BglII RFLP at the epidermal growth factor receptor locus (erbB-1) on chromosome 7. Nucleic Acids Res (1989) 0.75
Multicolor FISHs for simultaneous detection of genes and DNA segments on human chromosomes. Chromosome Res (2015) 0.75
DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A (1977) 790.54
Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol (1975) 503.08
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry (1979) 180.95
Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. Proc Natl Acad Sci U S A (1980) 109.70
Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing. J Mol Biol (1980) 61.16
A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments. Gene (1982) 59.01
Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. Nature (1984) 17.70
Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis. Nature (1981) 17.31
Amplification and characterization of a beta-globin gene synthesized in vitro. Cell (1976) 14.99
Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences. Nature (1984) 14.21
Epidermal growth factor and a new derivative. Rapid isolation procedures and biological and chemical characterization. J Biol Chem (1972) 10.86
Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells. Proc Natl Acad Sci U S A (1982) 10.50
Localization of single copy DNA sequences of G-banded human chromosomes by in situ hybridization. Chromosoma (1981) 9.30
Multiple arrangements of viral DNA and an activated host oncogene in bursal lymphomas. Nature (1982) 9.12
Simian sarcoma virus onc gene, v-sis, is derived from the gene (or genes) encoding a platelet-derived growth factor. Science (1983) 9.06
Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus. Nature (1983) 8.60
Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour. Nature (1983) 8.18
Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma. Proc Natl Acad Sci U S A (1983) 7.01
Onc gene amplification in promyelocytic leukaemia cell line HL-60 and primary leukaemic cells of the same patient. Nature (1982) 6.78
Nerve growth factor receptors on human melanoma cells in culture. Proc Natl Acad Sci U S A (1977) 6.62
Amplification of endogenous myc-related DNA sequences in a human myeloid leukaemia cell line. Nature (1982) 6.11
Translocation, breakage and truncated transcripts of c-myc oncogene in murine plasmacytomas. Nature (1983) 5.97
Autophosphorylation sites on the epidermal growth factor receptor. Nature (1984) 5.11
Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells. Cell (1981) 5.08
Localization of the c-ab1 oncogene adjacent to a translocation break point in chronic myelocytic leukaemia. Nature (1984) 4.30
Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane. Nature (1984) 4.27
Transcriptionally active c-myc oncogene is contained within NIARD, a DNA sequence associated with chromosome translocations in B-cell neoplasia. Proc Natl Acad Sci U S A (1983) 3.90
Translocation and rearrangements of the c-myc oncogene locus in human undifferentiated B-cell lymphomas. Science (1983) 3.82
The erbB gene of avian erythroblastosis virus is a member of the src gene family. Cell (1983) 3.82
A native 170,000 epidermal growth factor receptor-kinase complex from shed plasma membrane vesicles. J Biol Chem (1982) 3.81
Molecular cloning of the chromosomal breakpoint of B-cell lymphomas and leukemias with the t(11;14) chromosome translocation. Science (1984) 3.64
A cellular oncogene (c-Ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenocortical tumour cells. Nature (1983) 3.56
Activation of the cellular oncogene c-erbB by LTR insertion: molecular basis for induction of erythroblastosis by avian leukosis virus. Cell (1983) 3.45
Epidermal growth factor: receptors in human fibroblasts and modulation of action by cholera toxin. Proc Natl Acad Sci U S A (1973) 3.44
Differential expression of the translocated and the untranslocated c-myc oncogene in Burkitt lymphoma. Science (1983) 3.40
Cellular myc oncogene is altered by chromosome translocation to an immunoglobulin locus in murine plasmacytomas and is rearranged similarly in human Burkitt lymphomas. Proc Natl Acad Sci U S A (1983) 3.40
The T cell receptor beta chain genes are located on chromosome 6 in mice and chromosome 7 in humans. Cell (1984) 3.34
Amplification and enhanced expression of the epidermal growth factor receptor gene in A431 human carcinoma cells. Science (1984) 3.06
Activation of a translocated human c-myc gene by an enhancer in the immunoglobulin heavy-chain locus. Nature (1984) 2.93
Expression cloning of human EGF receptor complementary DNA: gene amplification and three related messenger RNA products in A431 cells. Science (1984) 2.75
DNA rearrangement and altered RNA expression of the c-myb oncogene in mouse plasmacytoid lymphosarcomas. Science (1983) 2.40
Specific radiolabeling of a cell surface receptor for epidermal growth factor. Proc Natl Acad Sci U S A (1977) 2.39
Human epidermal growth factor receptor cDNA is homologous to a variety of RNAs overproduced in A431 carcinoma cells. Nature (1984) 2.36
Evidence for the multiple oncogenic potential of cloned leukemia virus: in vitro and in vitro studies with avian erythroblastosis virus. Virology (1976) 2.28
Characterization of epidermal growth factor receptor gene expression in malignant and normal human cell lines. Proc Natl Acad Sci U S A (1984) 2.18
Increased expression of myc-related oncogene mRNA characterizes most BALB/c plasmacytomas induced by pristane or Abelson murine leukemia virus. Proc Natl Acad Sci U S A (1983) 2.16
Down-regulation of the epidermal growth factor receptor in KB cells is due to receptor internalization and subsequent degradation in lysosomes. Proc Natl Acad Sci U S A (1984) 2.11
Rearrangement and amplification of c-abl sequences in the human chronic myelogenous leukemia cell line K-562. Proc Natl Acad Sci U S A (1983) 2.08
Chromosomal localisation of the human homologues to the oncogenes erbA and B. EMBO J (1984) 2.02
A new avian erythroblastosis virus, AEV-H, carries erbB gene responsible for the induction of both erythroblastosis and sarcomas. Cell (1983) 1.95
Mapping of the human gene for epidermal growth factor receptor (EGFR) on the p13 leads to q22 region of chromosome 7. Cytogenet Cell Genet (1983) 1.50
Production of an epidermal growth factor receptor-related protein. Science (1984) 1.46
The epidermal growth factor receptor gene and its product. Nature (1984) 1.44
Biosynthesis of the epidermal growth factor receptor in A431 cells. EMBO J (1984) 1.43
The morphologic pathway of binding and internalization of epidermal growth factor in cultured cells. Studies on A431, KB, and 3T3 cells, using multiple methods of labelling. Exp Cell Res (1983) 1.40
Heritable fragile sites in cancer. Nature (1984) 1.38
A uniquely conserved regulatory signal is found around the translation initiation site in three different collagen genes. J Biol Chem (1983) 1.30
42,000-molecular weight EGF receptor has protein kinase activity. Nature (1984) 1.09
Enhanced synthesis and extracellular accumulation of hyaluronic acid during stimulation of quiescent human fibroblasts by mouse epidermal growth factor. J Cell Physiol (1976) 1.06
Genetics of cell surface receptors for bioactive polypeptides: binding of epidermal growth factor is associated with the presence of human chromosome 7 in human-mouse cell hybrids. Proc Natl Acad Sci U S A (1980) 1.03
Insulin and epidermal growth factor-urogastrone: affinity crosslinking to specific binding sites in rat liver membranes. Proc Natl Acad Sci U S A (1978) 1.01
Genetic analysis of hyperproduction of epidermal growth factor receptors in human epidermoid carcinoma A431 cells. Somat Cell Mol Genet (1984) 0.99
The mechanism of action of the epidermal growth factor. 3. Stimulation of the uptake of labeled precursors into RNA, DNA and proteins induced by EGF in isolated tumor cells. Hormones (1972) 0.96
Initial sequencing and analysis of the human genome. Nature (2001) 212.86
Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing. J Mol Biol (1980) 61.16
Sequence and organization of the human mitochondrial genome. Nature (1981) 57.39
A proposal for a uniform nomenclature in bacterial genetics. Genetics (1966) 31.92
The DNA sequence of human chromosome 22. Nature (1999) 30.88
The Influence of Ions upon the Action of Digitalis. Proc R Soc Med (1912) 24.21
The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection. Proc Natl Acad Sci U S A (1982) 20.55
Complete genome sequence of Salmonella enterica serovar Typhimurium LT2. Nature (2001) 16.89
A physical map of the human genome. Nature (2001) 12.39
Genetic location of certain mutations conferring recombination deficiency in Escherichia coli. J Bacteriol (1969) 11.34
The reaction between acetyl choline and muscle cells. J Physiol (1926) 9.75
Recombination deficient mutants of E. coli and other bacteria. Annu Rev Genet (1973) 9.55
Complete genome sequence of an M1 strain of Streptococcus pyogenes. Proc Natl Acad Sci U S A (2001) 9.40
Beginning a genetic analysis of conjugational transfer determined by the F factor in Escherichia coli by isolation and characterization of transfer-deficient mutants. J Bacteriol (1971) 8.45
Abnormal metabolic response to ultraviolet light of a recombination deficient mutant of Escherichia coli K12. J Mol Biol (1966) 8.39
Positional cloning of the gene for multiple endocrine neoplasia-type 1. Science (1997) 7.95
Genetic analysis of the recF pathway to genetic recombination in Escherichia coli K12: isolation and characterization of mutants. J Mol Biol (1973) 7.34
The beginning of a genetic analysis of recombination proficiency. J Cell Physiol (1967) 7.09
Characteristics of some multiply recombination-deficient strains of Escherichia coli. J Bacteriol (1969) 7.04
The antagonism of acetyl choline by atropine. J Physiol (1926) 6.99
High throughput fingerprint analysis of large-insert clones. Genome Res (1997) 6.91
Genetic recombination in Escherichia coli: the role of exonuclease I. Proc Natl Acad Sci U S A (1971) 6.74
Biochemical and genetic studies of recombination proficiency in Escherichia coli. I. Enzymatic activity associated with recB+ and recC+ genes. Proc Natl Acad Sci U S A (1970) 6.42
Behavior of lambda bacteriophage in a recombination deficienct strain of Escherichia coli. J Virol (1967) 6.38
Chromosome 22-specific low copy repeats and the 22q11.2 deletion syndrome: genomic organization and deletion endpoint analysis. Hum Mol Genet (2000) 6.21
Biochemical and genetic studies of recombination proficiency in Escherichia coli. II. Rec+ revertants caused by indirect suppression of rec- mutations. Proc Natl Acad Sci U S A (1970) 6.19
The complete nucleotide sequence of the Xenopus laevis mitochondrial genome. J Biol Chem (1985) 5.89
The action of ions upon the frog's heart. J Physiol (1921) 5.54
Subunit structure of islet-activating protein, pertussis toxin, in conformity with the A-B model. Biochemistry (1982) 5.33
The metabolism of the isolated heart of the frog. J Physiol (1931) 5.18
Analyses of the cag pathogenicity island of Helicobacter pylori. Mol Microbiol (1998) 5.07
Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Nature (1999) 5.03
Deletions generated by the transposon Tn10 in the srl recA region of the Escherichia coli K-12 chromosome. Genetics (1979) 4.75
Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome. Cell (1998) 4.72
Construction of an Hfr strain useful for transferring recA mutations between Escherichia coli strains. J Bacteriol (1980) 4.61
Recurrent DNMT3A mutations in patients with myelodysplastic syndromes. Leukemia (2011) 4.28
Abnormalities in structure and expression of the human retinoblastoma gene in SCLC. Science (1988) 4.26
The AZFc region of the Y chromosome features massive palindromes and uniform recurrent deletions in infertile men. Nat Genet (2001) 4.24
Characterization and sequence of the promoter region of the human epidermal growth factor receptor gene. Proc Natl Acad Sci U S A (1985) 4.08
The anaerobic activity of the isolated frog's heart. J Physiol (1932) 4.00
Detection and characterization of plasmids in Pseudomonas aeruginosa strain PAO. J Bacteriol (1973) 4.00
Genetic analysis of the RecE pathway of genetic recombination in Escherichia coli K-12. J Bacteriol (1981) 3.99
Epidermal-growth-factor-dependent transformation by a human EGF receptor proto-oncogene. Science (1987) 3.93
TGF alpha overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas. Cell (1990) 3.86
The action of ions and lipoids upon the frog's heart. J Physiol (1913) 3.78
Different pattern of codon recognition by mammalian mitochondrial tRNAs. Proc Natl Acad Sci U S A (1980) 3.74
Solution structure of a specific DNA complex of the Myb DNA-binding domain with cooperative recognition helices. Cell (1994) 3.74
Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I gene. N Engl J Med (1996) 3.73
Transformation and chromosome changes induced by Epstein-Barr virus in normal human leukocyte cultures. Proc Natl Acad Sci U S A (1969) 3.72
The oxygen consumption of the frog's heart: I. J Physiol (1928) 3.63
Promoter region of the human Harvey ras proto-oncogene: similarity to the EGF receptor proto-oncogene promoter. Science (1985) 3.59
Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene. Cell (1986) 3.59
Leucine zipper structure of the protein CRE-BP1 binding to the cyclic AMP response element in brain. EMBO J (1989) 3.56
Conjugal transmission of plasmids. Annu Rev Genet (1979) 3.34
CYP3A variation and the evolution of salt-sensitivity variants. Am J Hum Genet (2004) 3.32
Conjugational complementation analysis of transfer-deficient mutants of Flac in Escherichia coli. J Bacteriol (1972) 3.28
Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3. J Biol Chem (1999) 3.25
Accelerated transport and maturation of lysosomal alpha-galactosidase A in Fabry lymphoblasts by an enzyme inhibitor. Nat Med (1999) 3.11
CBP as a transcriptional coactivator of c-Myb. Genes Dev (1996) 3.09
Amplification and enhanced expression of the epidermal growth factor receptor gene in A431 human carcinoma cells. Science (1984) 3.06
On-line EM algorithm for the normalized gaussian network. Neural Comput (2000) 3.05
Indirect suppression of recB and recC mutations by exonuclease I deficiency. Proc Natl Acad Sci U S A (1972) 3.03
Multiple drug-resistant human KB carcinoma cells independently selected for high-level resistance to colchicine, adriamycin, or vinblastine show changes in expression of specific proteins. J Biol Chem (1986) 2.93
The carbohydrate metabolism of the isolated heart of the frog. J Physiol (1932) 2.92
Genetic analysis of the recJ gene of Escherichia coli K-12. J Bacteriol (1984) 2.90
Characterization of a human ovarian carcinoma cell line (NIH:OVCAR-3) with androgen and estrogen receptors. Cancer Res (1983) 2.90
The reaction between acetyl choline and muscle cells: Part II. J Physiol (1927) 2.89
Role of cytosolic phospholipase A2 in allergic response and parturition. Nature (1997) 2.88
Clonal diversity of recurrently mutated genes in myelodysplastic syndromes. Leukemia (2013) 2.85
Plasmid and bacteriophage vectors for excision of intact inserts. Gene (1987) 2.81
Molecular cloning of DNA from F sex factor of Escherichia coli K-12. Proc Natl Acad Sci U S A (1976) 2.81
Linkage of the angiotensinogen gene to essential hypertension. N Engl J Med (1994) 2.80
Characterization of REP- mutants and their interaction with P2 phage. Virology (1970) 2.77
PIK3CA as an oncogene in cervical cancer. Oncogene (2000) 2.75
Scarless endoscopic thyroidectomy: breast approach for better cosmesis. Surg Laparosc Endosc Percutan Tech (2000) 2.74
DNA sequencing with dye-labeled terminators and T7 DNA polymerase: effect of dyes and dNTPs on incorporation of dye-terminators and probability analysis of termination fragments. Nucleic Acids Res (1992) 2.71
Three-dimensional structure of Escherichia coli initiator tRNAfMet. Nature (1980) 2.70
Abnormal skeletal patterning in embryos lacking a single Cbp allele: a partial similarity with Rubinstein-Taybi syndrome. Proc Natl Acad Sci U S A (1997) 2.68
Acute lung injury by sepsis and acid aspiration: a key role for cytosolic phospholipase A2. Nat Immunol (2000) 2.67
Characterization of a cis-diamminedichloroplatinum(II)-resistant human ovarian cancer cell line and its use in evaluation of platinum analogues. Cancer Res (1987) 2.67
Synthesis of linear plasmid multimers in Escherichia coli K-12. J Bacteriol (1986) 2.65
Interaction of the recombination pathways of bacteriophage lambda and its host Escherichia coli K12: effects on exonuclease V activity. J Mol Biol (1972) 2.64
Toward a metabolic interpretation of genetic recombination of E. coli and its phages. Annu Rev Microbiol (1971) 2.61
Isolation of exonuclease VIII: the enzyme associated with sbcA indirect suppressor. Proc Natl Acad Sci U S A (1974) 2.60
Pharmacological management of chronic neuropathic pain - consensus statement and guidelines from the Canadian Pain Society. Pain Res Manag (2007) 2.59
Delineation of three functional domains of the transcriptional activator encoded by the c-myb protooncogene. Proc Natl Acad Sci U S A (1989) 2.59
[Methadone maintenance of HIV-infected drug addicts with immune deficiency]. Tidsskr Nor Laegeforen (1991) 2.57
A survey of prelicensure pain curricula in health science faculties in Canadian universities. Pain Res Manag (2009) 2.49