Published in Proc Natl Acad Sci U S A on April 01, 1986
A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation. J Virol (1988) 13.93
Virus attenuation by genome-scale changes in codon pair bias. Science (2008) 5.06
Poliovirus proteinase 2A induces cleavage of eucaryotic initiation factor 4F polypeptide p220. J Virol (1987) 4.52
Identification of an RNA hairpin in poliovirus RNA that serves as the primary template in the in vitro uridylylation of VPg. J Virol (2000) 3.14
Poliovirus host range is determined by a short amino acid sequence in neutralization antigenic site I. Science (1988) 3.03
Poliovirus polypeptide precursors: expression in vitro and processing by exogenous 3C and 2A proteinases. Proc Natl Acad Sci U S A (1987) 2.98
Infectious RNA transcribed from stably cloned full-length cDNA of dengue type 4 virus. Proc Natl Acad Sci U S A (1991) 2.97
Translation of poliovirus RNA: role of an essential cis-acting oligopyrimidine element within the 5' nontranslated region and involvement of a cellular 57-kilodalton protein. J Virol (1991) 2.86
Hepatitis A virus cDNA and its RNA transcripts are infectious in cell culture. J Virol (1987) 2.83
Studies on SP6 promoter using a new plasmid vector that allows gene insertion at the transcription initiation site. Nucleic Acids Res (1987) 2.79
Poliovirus chimeras replicating under the translational control of genetic elements of hepatitis C virus reveal unusual properties of the internal ribosomal entry site of hepatitis C virus. Proc Natl Acad Sci U S A (1996) 2.78
In vitro molecular genetics as a tool for determining the differential cleavage specificities of the poliovirus 3C proteinase. Nucleic Acids Res (1987) 2.77
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Role of 3'-end sequences in infectivity of poliovirus transcripts made in vitro. J Virol (1989) 2.52
Reduction of the rate of poliovirus protein synthesis through large-scale codon deoptimization causes attenuation of viral virulence by lowering specific infectivity. J Virol (2006) 2.51
Genetically engineered foot-and-mouth disease viruses with poly(C) tracts of two nucleotides are virulent in mice. J Virol (1993) 2.50
RGD sequence of foot-and-mouth disease virus is essential for infecting cells via the natural receptor but can be bypassed by an antibody-dependent enhancement pathway. Proc Natl Acad Sci U S A (1994) 2.49
Interaction between the 5'-terminal cloverleaf and 3AB/3CDpro of poliovirus is essential for RNA replication. J Virol (1995) 2.47
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Mutations in VP1 of poliovirus specifically affect both encapsidation and release of viral RNA. J Virol (1990) 2.25
Role of myristoylation of poliovirus capsid protein VP4 as determined by site-directed mutagenesis of its N-terminal sequence. EMBO J (1989) 2.24
A poliovirus replicon containing the chloramphenicol acetyltransferase gene can be used to study the replication and encapsidation of poliovirus RNA. J Virol (1992) 2.20
Construction of less neurovirulent polioviruses by introducing deletions into the 5' noncoding sequence of the genome. J Virol (1989) 2.19
Genetic and biochemical studies of poliovirus cis-acting replication element cre in relation to VPg uridylylation. J Virol (2000) 2.18
Polioviruses containing picornavirus type 1 and/or type 2 internal ribosomal entry site elements: genetic hybrids and the expression of a foreign gene. Proc Natl Acad Sci U S A (1994) 2.17
Poliovirus requires a precise 5' end for efficient positive-strand RNA synthesis. J Virol (2000) 2.16
Infectious in vitro transcripts from cowpea chlorotic mottle virus cDNA clones and exchange of individual RNA components with brome mosaic virus. J Virol (1988) 2.15
Analysis of RNA synthesis of type 1 poliovirus by using an in vitro molecular genetic approach. J Virol (1987) 2.14
Recovery of cytopathogenic and noncytopathogenic bovine viral diarrhea viruses from cDNA constructs. J Virol (1996) 2.13
In vitro construction of poliovirus defective interfering particles. J Virol (1989) 2.10
Processing of in vitro-synthesized gag precursor proteins of human immunodeficiency virus (HIV) type 1 by HIV proteinase generated in Escherichia coli. J Virol (1988) 2.09
Poliovirus type 1/type 3 antigenic hybrid virus constructed in vitro elicits type 1 and type 3 neutralizing antibodies in rabbits and monkeys. Proc Natl Acad Sci U S A (1988) 2.07
In vivo analysis of the promoter structure of the influenza virus RNA genome using a transfection system with an engineered RNA. Proc Natl Acad Sci U S A (1991) 2.03
Interaction of a cellular 57-kilodalton protein with the internal translation initiation site of foot-and-mouth disease virus. J Virol (1991) 1.97
Poliovirus RNA recombination: mechanistic studies in the absence of selection. EMBO J (1992) 1.94
Replication of poliovirus RNA and subgenomic RNA transcripts in transfected cells. J Virol (1992) 1.88
Genomic regions of neurovirulence and attenuation in Theiler murine encephalomyelitis virus. Proc Natl Acad Sci U S A (1990) 1.87
Mapping of attenuating sequences of an avirulent poliovirus type 2 strain. J Virol (1989) 1.85
Genetic mapping of the ability of Theiler's virus to persist and demyelinate. J Virol (1990) 1.82
Activity of purified biosynthetic proteinase of human immunodeficiency virus on natural substrates and synthetic peptides. Proc Natl Acad Sci U S A (1989) 1.81
The deletion of 41 proximal nucleotides reverts a poliovirus mutant containing a temperature-sensitive lesion in the 5' noncoding region of genomic RNA. J Virol (1989) 1.80
Genetic dissection of interaction between poliovirus 3D polymerase and viral protein 3AB. J Virol (1997) 1.79
Clustered charged-to-alanine mutagenesis of poliovirus RNA-dependent RNA polymerase yields multiple temperature-sensitive mutants defective in RNA synthesis. J Virol (1994) 1.79
Classical swine fever virus: recovery of infectious viruses from cDNA constructs and generation of recombinant cytopathogenic defective interfering particles. J Virol (1996) 1.74
Biochemical and genetic studies of the initiation of human rhinovirus 2 RNA replication: identification of a cis-replicating element in the coding sequence of 2A(pro). J Virol (2001) 1.74
Myristoylation of the poliovirus polyprotein is required for proteolytic processing of the capsid and for viral infectivity. J Virol (1990) 1.72
Characterization of poliovirus clones containing lethal and nonlethal mutations in the genome-linked protein VPg. J Virol (1990) 1.69
Mutational analysis of the genome-linked protein VPg of poliovirus. J Virol (1988) 1.66
Role for poliovirus protease 2A in cap independent translation. EMBO J (1994) 1.66
Retroviral vectors containing putative internal ribosome entry sites: development of a polycistronic gene transfer system and applications to human gene therapy. Nucleic Acids Res (1992) 1.66
The cardiovirulent phenotype of coxsackievirus B3 is determined at a single site in the genomic 5' nontranslated region. J Virol (1995) 1.64
Identification and characterization of the virus causing rabbit hemorrhagic disease. J Virol (1990) 1.64
Interaction of eukaryotic initiation factor eIF-4B with a picornavirus internal translation initiation site. J Virol (1995) 1.63
Determination of functional domains in polypyrimidine-tract-binding protein. Biochem J (1998) 1.63
Pathogenesis of mucosal disease: a cytopathogenic pestivirus generated by an internal deletion. J Virol (1994) 1.63
Construction of a "mutagenesis cartridge" for poliovirus genome-linked viral protein: isolation and characterization of viable and nonviable mutants. Proc Natl Acad Sci U S A (1988) 1.61
Evidence for emergence of diverse polioviruses from C-cluster coxsackie A viruses and implications for global poliovirus eradication. Proc Natl Acad Sci U S A (2007) 1.60
The DNA binding and oligomerization domain of MCM1 is sufficient for its interaction with other regulatory proteins. EMBO J (1991) 1.60
Molecular cloning of the complete genome of strain GDVII of Theiler's virus and production of infectious transcripts. J Virol (1989) 1.59
The 5'-terminal nucleotides of hepatitis A virus RNA, but not poliovirus RNA, are required for infectivity. J Virol (1991) 1.55
Infectious foot-and-mouth disease virus derived from a cloned full-length cDNA. J Virol (1990) 1.54
Identification of a single amino acid residue in the capsid protein VP1 of coxsackievirus B4 that determines the virulent phenotype. J Virol (1993) 1.54
Cytopathogenicity of classical swine fever virus caused by defective interfering particles. J Virol (1995) 1.53
Nucleotide sequences important for translation initiation of enterovirus RNA. J Virol (1991) 1.53
Infectious TYMV RNA from cloned cDNA: effects in vitro and in vivo of point substitutions in the initiation codons of two extensively overlapping ORFs. Nucleic Acids Res (1989) 1.50
Genetic analysis of a poliovirus/hepatitis C virus chimera: new structure for domain II of the internal ribosomal entry site of hepatitis C virus. J Virol (2001) 1.48
Synthetic viruses: a new opportunity to understand and prevent viral disease. Nat Biotechnol (2009) 1.47
Nucleotide sequence of a neurovirulent variant of the type 2 oral poliovirus vaccine. J Virol (1989) 1.46
Genetic analysis of a hydrophobic domain of coxsackie B3 virus protein 2B: a moderate degree of hydrophobicity is required for a cis-acting function in viral RNA synthesis. J Virol (1995) 1.43
Lack of myristoylation of poliovirus capsid polypeptide VP0 prevents the formation of virions or results in the assembly of noninfectious virus particles. J Virol (1990) 1.41
The in vitro-synthesized RNA from a cDNA clone of hepatitis E virus is infectious. J Virol (2000) 1.40
Biochemical and genetic studies of the VPg uridylylation reaction catalyzed by the RNA polymerase of poliovirus. J Virol (2003) 1.37
Poliovirus protein 3AB forms a complex with and stimulates the activity of the viral RNA polymerase, 3Dpol. J Virol (1995) 1.37
Functional dissection of a poliovirus cis-acting replication element [PV-cre(2C)]: analysis of single- and dual-cre viral genomes and proteins that bind specifically to PV-cre RNA. J Virol (2003) 1.37
The antiviral compound enviroxime targets the 3A coding region of rhinovirus and poliovirus. J Virol (1995) 1.37
A cysteine-rich motif in poliovirus protein 2C(ATPase) is involved in RNA replication and binds zinc in vitro. J Virol (2000) 1.35
Poliovirus infection enhances the formation of two ribonucleoprotein complexes at the 3' end of viral negative-strand RNA. J Virol (1995) 1.34
Development and application of a reverse genetics system for Japanese encephalitis virus. J Virol (2003) 1.34
Synthetic transcripts of double-stranded Birnavirus genome are infectious. Proc Natl Acad Sci U S A (1996) 1.33
Internal and terminal cis-acting sites are necessary for in vitro replication of the L-A double-stranded RNA virus of yeast. EMBO J (1989) 1.33
In vitro assembly of a functional nucleocapsid from the negative-stranded genome RNA of a defective interfering particle of vesicular stomatitis virus. Proc Natl Acad Sci U S A (1988) 1.31
Attenuated poliovirus strain as a live vector: expression of regions of rotavirus outer capsid protein VP7 by using recombinant Sabin 3 viruses. J Virol (1994) 1.31
An assembly defect as a result of an attenuating mutation in the capsid proteins of the poliovirus type 3 vaccine strain. J Virol (1991) 1.31
Expression of foreign proteins by poliovirus polyprotein fusion: analysis of genetic stability reveals rapid deletions and formation of cardioviruslike open reading frames. J Virol (1998) 1.30
Determinants of substrate recognition by poliovirus 2A proteinase. J Virol (1992) 1.29
Effect of mutations downstream of the internal ribosome entry site on initiation of poliovirus protein synthesis. J Virol (1994) 1.28
An antigen chimera of poliovirus induces antibodies against human papillomavirus type 16. J Virol (1990) 1.27
Mutations abrogating the RNase activity in glycoprotein E(rns) of the pestivirus classical swine fever virus lead to virus attenuation. J Virol (1999) 1.26
Mouse neurovirulence determinants of poliovirus type 1 strain LS-a map to the coding regions of capsid protein VP1 and proteinase 2Apro. J Virol (1994) 1.25
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