Published in Methods Enzymol on January 01, 1986
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An optimized electrofusion-based protocol for generating virus-specific human monoclonal antibodies. J Immunol Methods (2008) 1.61
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A human myeloma cell line suitable for the generation of human monoclonal antibodies. Proc Natl Acad Sci U S A (2001) 0.91
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Exclusion of a primary gene defect at the HLA locus in familial idiopathic dilated cardiomyopathy. J Med Genet (1995) 0.75
Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc Natl Acad Sci U S A (1993) 20.33
Characterization of the gene for a protein kinase which phosphorylates the sporulation-regulatory proteins Spo0A and Spo0F of Bacillus subtilis. J Bacteriol (1989) 4.20
A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration. Neuron (1999) 3.50
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The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates. J Biol Chem (1994) 2.82
Chemical induction of mGluR5- and protein synthesis--dependent long-term depression in hippocampal area CA1. J Neurophysiol (2001) 2.76
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The beige mutation in the mouse. I. A stem cell predetermined impairment in natural killer cell function. J Immunol (1979) 2.11
The receptor tyrosine kinase EphB2 regulates NMDA-dependent synaptic function. Neuron (2001) 2.02
The beige mutation in the mouse. II. Selectivity of the natural killer (NK) cell defect. J Immunol (1979) 2.02
Multidrug resistance in a human small cell lung cancer cell line selected in adriamycin. Cancer Res (1987) 1.88
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A new immunodeficiency disorder in humans involving NK cells. Nature (1980) 1.78
Recognition of myelin-associated glycoprotein by the monoclonal antibody HNK-1. Nature (1984) 1.77
Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport. J Biol Chem (1996) 1.74
Regulation of T cell activation, anxiety, and male aggression by RGS2. Proc Natl Acad Sci U S A (2000) 1.73
Human hybridomas constructed with antigen-specific Epstein-Barr virus-transformed cell lines. Proc Natl Acad Sci U S A (1982) 1.73
Target-effector interaction in the natural killer cell system: isolation of target structures. Proc Natl Acad Sci U S A (1979) 1.71
Target--effector interaction in the natural killer cell system. I. Covariance and genetic control of cytolytic and target-cell-binding subpopulations in the mouse. Scand J Immunol (1978) 1.70
Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters. Toxicology (2001) 1.66
Structural, mechanistic and clinical aspects of MRP1. Biochim Biophys Acta (1999) 1.62
Amplification of the c-myc oncogene in one of five human breast carcinoma cell lines. Cancer Res (1984) 1.54
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Multidrug resistance proteins MRP3, MRP1, and MRP2 in lung cancer: correlation of protein levels with drug response and messenger RNA levels. Clin Cancer Res (2001) 1.47
Atypical multidrug resistance: breast cancer resistance protein messenger RNA expression in mitoxantrone-selected cell lines. J Natl Cancer Inst (1999) 1.46
Requirements for the establishment of high-titered human monoclonal antibodies against tetanus toxoid using the Epstein-Barr virus technique. J Immunol (1981) 1.45
Low natural in vivo resistance to syngeneic leukaemias in natural killer-deficient mice. Nature (1980) 1.42
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Reduced fear and aggression and altered serotonin metabolism in Gtf2ird1-targeted mice. Genes Brain Behav (2007) 1.37
Comparison of the functional characteristics of the nucleotide binding domains of multidrug resistance protein 1. J Biol Chem (2000) 1.36
Regulation of human beta-defensins by gastric epithelial cells in response to infection with Helicobacter pylori or stimulation with interleukin-1. Infect Immun (2000) 1.33
Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): evidence for cotransport with reduced glutathione. Cancer Res (1998) 1.32
Evidence that many of the DISC1 isoforms in C57BL/6J mice are also expressed in 129S6/SvEv mice. Mol Psychiatry (2007) 1.32
High level functional engraftment of severe combined immunodeficient mice with human peripheral blood lymphocytes following pretreatment with radiation and anti-asialo GM1. J Immunol Methods (1994) 1.32
ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pump. Biochem J (1996) 1.29
Recombinant myelin-associated glycoprotein confers neural adhesion and neurite outgrowth function. Neuron (1989) 1.25
Membrane topology of the multidrug resistance protein (MRP). A study of glycosylation-site mutants reveals an extracytosolic NH2 terminus. J Biol Chem (1997) 1.25
The mobilization regions of two integrated Bacteroides elements, NBU1 and NBU2, have only a single mobilization protein and may be on a cassette. J Bacteriol (1995) 1.24
Protective role of beta-chemokines associated with HIV-specific Th responses against perinatal HIV transmission. J Immunol (1999) 1.24
Multidrug resistance mediated by the multidrug resistance protein (MRP) gene. Biochem Pharmacol (1996) 1.23
Chemiluminescence response of human natural killer cells. I. The relationship between target cell binding, chemiluminescence, and cytolysis. J Exp Med (1982) 1.23
Oxygen intermediates are triggered early in the cytolytic pathway of human NK cells. Nature (1982) 1.22
Localization of a novel multidrug resistance-associated gene in the HT1080/DR4 and H69AR human tumor cell lines. Cancer Res (1993) 1.21
Target-effector interaction in the natural killer cell system. IV. Modulation by cyclic nucleotides. J Immunol (1979) 1.20
An expanded population of natural killer cells in mice with severe combined immunodeficiency (SCID) lack rearrangement and expression of T cell receptor genes. J Exp Med (1986) 1.19
Organization of a repetitive human 1.8 kb KpnI sequence localized in the heterochromatin of chromosome 15. Chromosoma (1985) 1.19
Detection of the M(r) 190,000 multidrug resistance protein, MRP, with monoclonal antibodies. Cancer Res (1994) 1.18
Biosynthesis of the antibiotic actinorhodin. Analysis of blocked mutants of Streptomyces coelicolor. J Antibiot (Tokyo) (1987) 1.18
Modulation of NMDA receptors by pituitary adenylate cyclase activating peptide in CA1 neurons requires G alpha q, protein kinase C, and activation of Src. J Neurosci (2005) 1.18
Expression of multidrug resistance protein-related genes in lung cancer: correlation with drug response. Clin Cancer Res (1999) 1.17
Clinical significance of multi-drug resistance associated protein and P-glycoprotein in patients with bladder cancer. J Urol (1997) 1.16
Target-effector cell interaction in the natural killer cell system. V. Energy requirements, membrane integrity, and the possible involvement of lysosomal enzymes. Immunology (1980) 1.15
Tp44 molecules involved in antigen-independent T cell activation are expressed on human plasma cells. J Immunol (1987) 1.13
Studies of human natural killer cells. II. Analysis at the single cell level. J Immunol (1982) 1.13
ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids. J Biol Chem (1996) 1.12
A functional comparison of tumor cell killing by activated macrophages and natural killer cells. Eur J Immunol (1979) 1.12
Binding specificities of the sialoadhesin family of I-type lectins. Sialic acid linkage and substructure requirements for binding of myelin-associated glycoprotein, Schwann cell myelin protein, and sialoadhesin. J Biol Chem (1997) 1.12
The biology of the human natural killer cell. J Clin Immunol (1982) 1.11
The structure of the multidrug resistance protein 1 (MRP1/ABCC1). crystallization and single-particle analysis. J Biol Chem (2001) 1.11
Inducible cellular transformation by a metallothionein-ras hybrid oncogene leads to natural killer cell susceptibility. Nature (1986) 1.11
Impaired cerebellar synaptic plasticity and motor performance in mice lacking the mGluR4 subtype of metabotropic glutamate receptor. J Neurosci (1996) 1.11
Mutation of Trp1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity. J Biol Chem (2001) 1.11
Studies on antibody levels to Brucella abortus, Toxoplasma gondii and Leptospira serogroups in sera collected by the National Serum Bank during 1974-1976. Zentralbl Bakteriol Orig A (1979) 1.10
Function, evolution and structure of multidrug resistance protein (MRP). Semin Cancer Biol (1997) 1.10
Suppressor cells in immunosenescence. Fed Proc (1978) 1.08
Use of the MTT assay for rapid determination of chemosensitivity of human leukemic blast cells. Leuk Res (1988) 1.07
Intra-rectal injection of tumour cells: a novel animal model of rectal cancer. Surg Oncol (1992) 1.06
Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and atpase activities by interaction with dietary flavonoids. Mol Pharmacol (2001) 1.06
Characterization of the M(r) 190,000 multidrug resistance protein (MRP) in drug-selected and transfected human tumor cell. Cancer Res (1995) 1.06
Human anti-tetanus toxoid monoclonal antibody secreted by EBV-transformed human B cells fused with murine myeloma. Hybridoma (1982) 1.04
Enhanced dopamine function in DISC1-L100P mutant mice: implications for schizophrenia. Genes Brain Behav (2010) 1.04
Expression of multidrug resistance-associated protein (MRP) mRNA in blast cells from acute myeloid leukemia (AML) patients. Leukemia (1996) 1.04
Pharmacological characterization of the murine and human orthologs of multidrug-resistance protein in transfected human embryonic kidney cells. Mol Pharmacol (1997) 1.04
Multiple behavioral anomalies in GluR2 mutant mice exhibiting enhanced LTP. Behav Brain Res (1998) 1.03
Photodynamic therapy augments the efficacy of oncolytic vaccinia virus against primary and metastatic tumours in mice. Br J Cancer (2011) 1.03
Src potentiation of NMDA receptors in hippocampal and spinal neurons is not mediated by reducing zinc inhibition. J Neurosci (1999) 1.03
High-fat, high-cholesterol diet increases the incidence of gastritis in LDL receptor-negative mice. Arterioscler Thromb Vasc Biol (2001) 1.02
Inhibition of hepatic ferrochelatase by the four isomers of N-methylprotoporphyrin IX. Biochem Biophys Res Commun (1980) 1.02
Identification of human multidrug resistance protein 1 (MRP1) mutations and characterization of a G671V substitution. J Hum Genet (2001) 1.02
Sequential coexpression of the multidrug resistance genes MRP and mdr1 and their products in VP-16 (etoposide)-selected H69 small cell lung cancer cells. Cancer Res (1995) 1.02
Establishment of a human large cell lung tumor line (QU-DB) with metastatic properties in athymic mice. Cancer (1986) 1.01
The Lurcher mutation of an alpha-amino-3-hydroxy-5-methyl- 4-isoxazolepropionic acid receptor subunit enhances potency of glutamate and converts an antagonist to an agonist. J Biol Chem (2000) 1.01
Cytokine patterns during progression to AIDS in children with perinatal HIV infection. J Immunol (1995) 1.01
Diminished HIV-specific CTL activity is associated with lower type 1 and enhanced type 2 responses to HIV-specific peptides during perinatal HIV infection. J Immunol (1997) 1.00
Evidence that the MYCN oncogene regulates MRP gene expression in neuroblastoma. Eur J Cancer (1997) 1.00
Natural killer (HNK-1+) cells in Chediak-Higashi patients are present in normal numbers but are abnormal in function and morphology. J Clin Invest (1982) 1.00
Decreased neuronal Na+, K+ -ATPase activity in Atp1a3 heterozygous mice increases susceptibility to depression-like endophenotypes by chronic variable stress. Genes Brain Behav (2011) 1.00
Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport. J Biol Chem (2001) 0.99
Identification of an amino acid residue in multidrug resistance protein 1 critical for conferring resistance to anthracyclines. J Biol Chem (2001) 0.99
Inwardly rectifying K+ channels and volume-regulated anion channels in multidrug-resistant small cell lung cancer cells. Cancer Res (1993) 0.99
Myelin-associated glycoprotein, a cell adhesion molecule of oligodendrocytes, is phosphorylated in brain. Mol Cell Biol (1988) 0.99