Published in Jpn J Pharmacol on November 01, 1986
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Calcitonin gene-related peptide enhances the rate of desensitization of the nicotinic acetylcholine receptor in cultured mouse muscle cells. Proc Natl Acad Sci U S A (1988) 1.29
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A highly sensitive method to assay FK-506 levels in plasma. Transplant Proc (1987) 8.45
DNA damage-induced activation of p53 by the checkpoint kinase Chk2. Science (2000) 7.85
The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract. Nature (1998) 7.38
E-CELL: software environment for whole-cell simulation. Bioinformatics (1999) 6.29
Nalidixic acid-resistant mutations of the gyrB gene of Escherichia coli. Mol Gen Genet (1986) 5.95
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Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death. Nature (2001) 5.07
Cloning and expression of apical membrane water channel of rat kidney collecting tubule. Nature (1993) 4.99
In vitro and in vivo antibacterial activities of AT-4140, a new broad-spectrum quinolone. Antimicrob Agents Chemother (1989) 4.79
Calyculin A and okadaic acid: inhibitors of protein phosphatase activity. Biochem Biophys Res Commun (1989) 4.63
Reduced angiogenesis and tumor progression in gelatinase A-deficient mice. Cancer Res (1998) 4.39
Expression and function of the interleukin 7 receptor in murine lymphocytes. Proc Natl Acad Sci U S A (1993) 4.35
Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum. Nature (1998) 4.18
Therapeutic potential of ex vivo expanded endothelial progenitor cells for myocardial ischemia. Circulation (2001) 4.17
Quinolone resistance mutations in the DNA gyrase gyrA and gyrB genes of Staphylococcus aureus. Antimicrob Agents Chemother (1994) 3.96
New ages for the last Australian megafauna: continent-wide extinction about 46,000 years ago. Science (2001) 3.91
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Association of the encapsulation of Bacillus anthracis with a 60 megadalton plasmid. J Gen Microbiol (1985) 3.64
Signalling from endoplasmic reticulum to nucleus: transcription factor with a basic-leucine zipper motif is required for the unfolded protein-response pathway. Genes Cells (1996) 3.58
Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress. J Biol Chem (2001) 3.46
Histologic improvement of fibrosis in patients with hepatitis C who have sustained response to interferon therapy. Ann Intern Med (2000) 3.44
A prospective randomised study of "covered" versus "uncovered" diamond stents for the management of distal malignant biliary obstruction. Gut (2004) 3.35
IFNβ-1b may severely exacerbate Japanese optic-spinal MS in neuromyelitis optica spectrum. Neurology (2010) 3.34
Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia. Proc Natl Acad Sci U S A (1987) 3.32
Induction of various autoantibodies by mutant gene lpr in several strains of mice. J Immunol (1984) 3.20
The membrane-anchored MMP inhibitor RECK is a key regulator of extracellular matrix integrity and angiogenesis. Cell (2001) 2.97
Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition. Science (1999) 2.96
Presynaptic inhibition caused by retrograde signal from metabotropic glutamate to cannabinoid receptors. Neuron (2001) 2.94
Human centromere protein A (CENP-A) can replace histone H3 in nucleosome reconstitution in vitro. Proc Natl Acad Sci U S A (2000) 2.91
Major virulence factors, VacA and CagA, are commonly positive in Helicobacter pylori isolates in Japan. Gut (1998) 2.84
Familial gastrointestinal stromal tumours with germline mutation of the KIT gene. Nat Genet (1998) 2.80
Development of a compact computed tomographic apparatus for dental use. Dentomaxillofac Radiol (1999) 2.79
An intrinsic bond-centered electronic glass with unidirectional domains in underdoped cuprates. Science (2007) 2.76
Analysis of K-ras gene mutation in hyperplastic duct cells of the pancreas without pancreatic disease. Gastroenterology (1996) 2.59
Occurrence of tetrodotoxin and anhydrotetrodotoxin in Vibrio sp. isolated from the intestines of a xanthid crab, Atergatis floridus. J Biochem (1986) 2.56
Genetic evidence for functional redundancy of Platelet/Endothelial cell adhesion molecule-1 (PECAM-1): CD31-deficient mice reveal PECAM-1-dependent and PECAM-1-independent functions. J Immunol (1999) 2.55
In vitro generation of lymphohematopoietic cells from endothelial cells purified from murine embryos. Immunity (1998) 2.54
Molecular cloning and expression of a member of the aquaporin family with permeability to glycerol and urea in addition to water expressed at the basolateral membrane of kidney collecting duct cells. Proc Natl Acad Sci U S A (1994) 2.54
Serum uric acid and risk for development of hypertension and impaired fasting glucose or Type II diabetes in Japanese male office workers. Eur J Epidemiol (2003) 2.52
Enterovirus 71 from fatal and nonfatal cases of hand, foot and mouth disease epidemics in Malaysia, Japan and Taiwan in 1997-1998. Jpn J Infect Dis (1999) 2.52
Monensin and FCCP inhibit the intracellular transport of alphavirus membrane glycoproteins. J Cell Biol (1980) 2.50
Correlation between the presence of a fifty-megadalton plasmid in Salmonella dublin and virulence for mice. Infect Immun (1983) 2.46
An intracellular protein that binds amyloid-beta peptide and mediates neurotoxicity in Alzheimer's disease. Nature (1997) 2.42
Interplay of electron-lattice interactions and superconductivity in superconductivity in Bi2Sr2CaCu2O8+delta. Nature (2006) 2.40
Virulence factors of Helicobacter pylori responsible for gastric diseases in Mongolian gerbil. J Exp Med (2000) 2.37
Two cis-acting elements in the 3' untranslated region of alpha-CaMKII regulate its dendritic targeting. Nat Neurosci (2000) 2.34
Induction of cytotoxicity by photoexcited TiO2 particles. Cancer Res (1992) 2.31
Eccrine adenocarcinoma. A clinicopathologic study of 35 cases. Arch Dermatol (1983) 2.30
Cloning of the cDNa for a Na+/myo-inositol cotransporter, a hypertonicity stress protein. J Biol Chem (1992) 2.28
Functional expression and germline transmission of a human chromosome fragment in chimaeric mice. Nat Genet (1997) 2.28
How Cooper pairs vanish approaching the Mott insulator in Bi2Sr2CaCu2O8+delta. Nature (2008) 2.27
Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkappaB activation in primary hippocampal neurons. J Biol Chem (1999) 2.27
Structure of cag pathogenicity island in Japanese Helicobacter pylori isolates. Gut (1999) 2.25
Human Tra2 proteins are sequence-specific activators of pre-mRNA splicing. Cell (1998) 2.25
Platelet-activating factor acetylhydrolase deficiency. A missense mutation near the active site of an anti-inflammatory phospholipase. J Clin Invest (1996) 2.21
HMG-CoA reductase inhibitor mobilizes bone marrow--derived endothelial progenitor cells. J Clin Invest (2001) 2.20
Mouse Wnt receptor gene Fzd5 is essential for yolk sac and placental angiogenesis. Development (2001) 2.19
Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis. J Clin Invest (2001) 2.15
Ectodomain shedding of epidermal growth factor receptor ligands is required for keratinocyte migration in cutaneous wound healing. J Cell Biol (2000) 2.14
Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response. Nat Cell Biol (1999) 2.14
Vascular endothelial growth factor can substitute for macrophage colony-stimulating factor in the support of osteoclastic bone resorption. J Exp Med (1999) 2.13
Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells. EMBO J (1999) 2.10
Intra-unit-cell electronic nematicity of the high-T(c) copper-oxide pseudogap states. Nature (2010) 2.10
mGluR1 in cerebellar Purkinje cells essential for long-term depression, synapse elimination, and motor coordination. Science (2000) 2.09
Proline-directed and non-proline-directed phosphorylation of PHF-tau. J Biol Chem (1995) 2.09
The relationship between facet joint osteoarthritis and disc degeneration of the lumbar spine: an MRI study. Eur Spine J (1999) 2.07
Walking speed as a good predictor for the onset of functional dependence in a Japanese rural community population. Age Ageing (2000) 1.99
Relating atomic-scale electronic phenomena to wave-like quasiparticle states in superconducting Bi2Sr2CaCu2O8+delta. Nature (2003) 1.98
Complete nucleotide sequence of the 26S rRNA gene of Physarum polycephalum: its significance in gene evolution. Proc Natl Acad Sci U S A (1983) 1.98
Increased expression of transforming growth factor-beta1 in small airway epithelium from tobacco smokers and patients with chronic obstructive pulmonary disease (COPD). Am J Respir Crit Care Med (2001) 1.98
The diagnosis of a DRESS syndrome has been sufficiently established on the basis of typical clinical features and viral reactivations. Br J Dermatol (2007) 1.97
Afadin: A key molecule essential for structural organization of cell-cell junctions of polarized epithelia during embryogenesis. J Cell Biol (1999) 1.96
Cloning of a Na(+)- and Cl(-)-dependent betaine transporter that is regulated by hypertonicity. J Biol Chem (1992) 1.93
Progressive impairment of kidneys and reproductive organs in mice lacking Rho GDIalpha. Oncogene (1999) 1.91
Motor discoordination and increased susceptibility to cerebellar injury in GLAST mutant mice. Eur J Neurosci (1998) 1.90
Prevalence of radiographic knee osteoarthritis and its association with knee pain in the elderly of Japanese population-based cohorts: the ROAD study. Osteoarthritis Cartilage (2009) 1.90
Rfc5, a small subunit of replication factor C complex, couples DNA replication and mitosis in budding yeast. Proc Natl Acad Sci U S A (1996) 1.89
Intercellular spaces of the human epidermis as demonstrated with lanthanum. J Invest Dermatol (1971) 1.89
Cloning and expression of a protein kinase C-regulated chloride channel abundantly expressed in rat brain neuronal cells. Neuron (1994) 1.89
Intrarenal and cellular localization of CLC-K2 protein in the mouse kidney. J Am Soc Nephrol (2001) 1.88
Genetic studies of autoimmunity in New Zealand mice. III. Associations among anti-DNA antibodies, NTA, and renal disease in (NZB x NZW)F1 x NZW backcross mice. J Immunol (1981) 1.88
Incomplete growth of simian virus 40 in African green monkey kidney culture induced by serial undiluted passages. Virology (1966) 1.87
Identification of hypoxia-inducible factor 1 ancillary sequence and its function in vascular endothelial growth factor gene induction by hypoxia and nitric oxide. J Biol Chem (2000) 1.86
Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth. Mol Psychiatry (2003) 1.86
Inhibition of myo-inositol transport causes acute renal failure with selective medullary injury in the rat. Kidney Int (1998) 1.85
Short-term stimulation of the thiazide-sensitive Na+-Cl- cotransporter by vasopressin involves phosphorylation and membrane translocation. Am J Physiol Renal Physiol (2009) 1.85
Ultrasound-guided radiofrequency thermal ablation of liver tumors: percutaneous, laparoscopic, and open surgical approaches. J Gastrointest Surg (2002) 1.84
Marine bacteria which produce tetrodotoxin. Appl Environ Microbiol (1987) 1.84
Changes in bradykinin level in coronary sinus blood after the experimental occlusion of a coronary artery. Am Heart J (1973) 1.83
Overt nephrogenic diabetes insipidus in mice lacking the CLC-K1 chloride channel. Nat Genet (1999) 1.83
Atomic-Scale Sources and Mechanism of Nanoscale Electronic Disorder in Bi2Sr2CaCu2O8+delta. Science (2005) 1.82
The relationship between disc degeneration, facet joint osteoarthritis, and stability of the degenerative lumbar spine. J Spinal Disord (2000) 1.81