Published in Biochemistry on December 30, 1986
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Advancements in gene transfer-based therapy for hemophilia A. Expert Rev Hematol (2009) 0.83
Optimizing antibody expression by using the naturally occurring framework diversity in a live bacterial antibody display system. Sci Rep (2015) 0.79
Structural model of porcine factor VIII and factor VIIIa molecules based on scanning transmission electron microscope (STEM) images and STEM mass analysis. J Clin Invest (1990) 0.79
In vitro affinity maturation of a natural human antibody overcomes a barrier to in vivo affinity maturation. MAbs (2014) 0.78
Factor VIII light chain contains a binding site for factor X that contributes to the catalytic efficiency of factor Xase. Biochemistry (2012) 0.78
Characterization of des-(741-1668)-factor VIII, a single-chain factor VIII variant with a fusion site susceptible to proteolysis by thrombin and factor Xa. Biochem J (1995) 0.78
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Prospects for the use of artificial chromosomes and minichromosome-like episomes in gene therapy. J Biomed Biotechnol (2010) 0.76
A broadly protective therapeutic antibody against influenza B virus with two mechanisms of action. Nat Commun (2017) 0.75
Evading pre-existing anti-hinge antibody binding by hinge engineering. MAbs (2016) 0.75
Effector attenuating substitutions that maintain antibody stability and reduce toxicity in mice. J Biol Chem (2017) 0.75
Variable contributions of basic residues forming an APC exosite in the binding and inactivation of factor VIIIa. Biochemistry (2013) 0.75
The Dual Regulatory Role of Amino Acids Leu480 and Gln481 of Prothrombin. J Biol Chem (2015) 0.75
Novel factor VIII variants with a modified furin cleavage site improve the efficacy of gene therapy for hemophilia A. J Thromb Haemost (2016) 0.75
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Base composition-independent hybridization in tetramethylammonium chloride: a method for oligonucleotide screening of highly complex gene libraries. Proc Natl Acad Sci U S A (1985) 13.19
Host-specific activation of transcription by tandem repeats from simian virus 40 and Moloney murine sarcoma virus. Proc Natl Acad Sci U S A (1982) 12.30
Human lipoprotein lipase complementary DNA sequence. Science (1987) 9.50
The nucleotide sequence of the human beta-globin gene. Cell (1980) 8.11
High efficiency DNA-mediated transformation of primate cells. Science (1983) 8.09
Recombinant human tumor necrosis factor-alpha: effects on proliferation of normal and transformed cells in vitro. Science (1985) 7.99
Molecular cloning and characterization of the human beta-like globin gene cluster. Cell (1980) 7.77
Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors. Science (1997) 6.82
Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling. Nature (1998) 6.49
A 200 base pair region at the 5' end of the chicken adult beta-globin gene is accessible to nuclease digestion. Cell (1981) 6.43
Human tumor necrosis factor. Production, purification, and characterization. J Biol Chem (1985) 6.28
Characterization of the human factor VIII gene. Nature (1984) 5.37
Cloning and expression of human tissue-type plasminogen activator cDNA in E. coli. Nature (1983) 5.27
Neutrophil and B cell expansion in mice that lack the murine IL-8 receptor homolog. Science (1994) 5.20
Characterization of receptors for human tumour necrosis factor and their regulation by gamma-interferon. Nature (1986) 4.98
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cDNA sequence of human apolipoprotein(a) is homologous to plasminogen. Nature (1987) 4.54
The structure of eight distinct cloned human leukocyte interferon cDNAs. Nature (1981) 4.50
The factor structure and factor stability of the hospital anxiety and depression scale in patients with cancer. Br J Psychiatry (1991) 4.43
Growth hormone receptor and serum binding protein: purification, cloning and expression. Nature (1988) 4.40
Expression of active human factor VIII from recombinant DNA clones. Nature (1984) 4.36
Characterisation of deletions which affect the expression of fetal globin genes in man. Nature (1979) 4.18
Structure of human factor VIII. Nature (1984) 3.29
IGF-I is required for normal embryonic growth in mice. Genes Dev (1993) 3.17
Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand. Nature (1994) 3.13
Endothelial interleukin-8: a novel inhibitor of leukocyte-endothelial interactions. Science (1989) 3.06
Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer. Nature (1998) 2.98
The sequence of human serum albumin cDNA and its expression in E. coli. Nucleic Acids Res (1981) 2.97
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ABCA1 is the cAMP-inducible apolipoprotein receptor that mediates cholesterol secretion from macrophages. J Biol Chem (2000) 2.82
Proteolytic processing of human factor VIII. Correlation of specific cleavages by thrombin, factor Xa, and activated protein C with activation and inactivation of factor VIII coagulant activity. Biochemistry (1986) 2.77
Vascular endothelial growth factor-related protein: a ligand and specific activator of the tyrosine kinase receptor Flt4. Proc Natl Acad Sci U S A (1996) 2.77
A generic intron increases gene expression in transgenic mice. Mol Cell Biol (1991) 2.75
Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R. J Biol Chem (2000) 2.73
Human apolipoprotein D gene: gene sequence, chromosome localization, and homology to the alpha 2u-globulin superfamily. DNA (1987) 2.67
Genetic mapping and diagnosis of haemophilia A achieved through a BclI polymorphism in the factor VIII gene. Nature (1985) 2.61
Tracing the first stars with fluctuations of the cosmic infrared background. Nature (2005) 2.60
Chemokine binding and activities mediated by the mouse IL-8 receptor. J Immunol (1995) 2.59
IL-17E, a novel proinflammatory ligand for the IL-17 receptor homolog IL-17Rh1. J Biol Chem (2001) 2.50
Influence of the codon following the AUG initiation codon on the expression of a modified lacZ gene in Escherichia coli. EMBO J (1987) 2.46
The serum concentration of active transforming growth factor-beta is severely depressed in advanced atherosclerosis. Nat Med (1995) 2.42
Detection and sequence of mutations in the factor VIII gene of haemophiliacs. Nature (1985) 2.30
Differential responses of human tumor cell lines to anti-p185HER2 monoclonal antibodies. Cancer Immunol Immunother (1993) 2.25
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ABCA1. The gatekeeper for eliminating excess tissue cholesterol. J Lipid Res (2001) 2.08
Cloning and characterization of IL-17B and IL-17C, two new members of the IL-17 cytokine family. Proc Natl Acad Sci U S A (2000) 2.06
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Characterization of the human growth hormone receptor gene and demonstration of a partial gene deletion in two patients with Laron-type dwarfism. Proc Natl Acad Sci U S A (1989) 1.95
Solution structure of the fourth metal-binding domain from the Menkes copper-transporting ATPase. Nat Struct Biol (1998) 1.95
Molecular genetics of human serum albumin: restriction enzyme fragment length polymorphisms and analbuminemia. Proc Natl Acad Sci U S A (1983) 1.89
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Cardiotrophin-1. Biological activities and binding to the leukemia inhibitory factor receptor/gp130 signaling complex. J Biol Chem (1995) 1.83
Evaluation of the Cd/hemoglobin affinity assay for the rapid determination of metallothionein in biological tissues. Toxicol Appl Pharmacol (1982) 1.82
Prevalence of type-specific HPV infection by age and grade of cervical cytology: data from the ARTISTIC trial. Br J Cancer (2008) 1.77
The gene-size DNA molecules in Oxytricha. Cold Spring Harb Symp Quant Biol (1978) 1.75
A new polymorphism in the factor VIII gene for prenatal diagnosis of hemophilia A. Nucleic Acids Res (1986) 1.74
Cardiotrophin-1 activates a distinct form of cardiac muscle cell hypertrophy. Assembly of sarcomeric units in series VIA gp130/leukemia inhibitory factor receptor-dependent pathways. J Biol Chem (1996) 1.69
Isolation of a cDNA clone coding for the gamma-subunit of mouse nerve growth factor using a high-stringency selection procedure. DNA (1984) 1.64
Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR. Curr Biol (1999) 1.63
Induction of phase I and phase II drug-metabolizing enzyme mRNA, protein, and activity by BHA, ethoxyquin, and oltipraz. Toxicol Appl Pharmacol (1995) 1.62
Partial amino acid sequence of apolipoprotein(a) shows that it is homologous to plasminogen. Proc Natl Acad Sci U S A (1987) 1.61
Chromatin structure of the chicken beta-globin gene region. Sensitivity to DNase I, micrococcal nuclease, and DNase II. J Biol Chem (1982) 1.61
Identification of a missense mutation in the factor VIII gene of a mild hemophiliac. Science (1986) 1.60
Functionalized pentacene: improved electronic properties from control of solid-state order. J Am Chem Soc (2001) 1.59
DNA sequence of two closely linked human leukocyte interferon genes. Science (1981) 1.57
Cloning and expression of the cDNA for human antithrombin III. Nucleic Acids Res (1982) 1.55
Percutaneous ostomy dilation: a technique for dilating the closed percutaneous endoscopic gastrostomy sites and reinserting gastrostomies. Gastrointest Endosc (1989) 1.54
DNA sequence of a major human leukocyte interferon gene. Proc Natl Acad Sci U S A (1981) 1.53
Determination of temporal expression patterns for multiple genes in the rat carotid artery injury model. Arterioscler Thromb Vasc Biol (2000) 1.51
Apolipoprotein(a) size heterogeneity is related to variable number of repeat sequences in its mRNA. Biochemistry (1990) 1.51