PubRank

A F Stewart

Author PubWeight™ 228.07‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A new logic for DNA engineering using recombination in Escherichia coli. Nat Genet 1998 15.27
2 High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP. Nat Genet 2000 11.80
3 The PHD finger: implications for chromatin-mediated transcriptional regulation. Trends Biochem Sci 1995 6.97
4 Rapid modification of bacterial artificial chromosomes by ET-recombination. Nucleic Acids Res 1999 6.85
5 The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4. EMBO J 2001 5.34
6 DNA cloning by homologous recombination in Escherichia coli. Nat Biotechnol 2000 4.75
7 Improved properties of FLP recombinase evolved by cycling mutagenesis. Nat Biotechnol 1998 4.14
8 The SANT domain: a putative DNA-binding domain in the SWI-SNF and ADA complexes, the transcriptional co-repressor N-CoR and TFIIIB. Trends Biochem Sci 1996 3.55
9 Biochemical evaluation of patients with cancer-associated hypercalcemia: evidence for humoral and nonhumoral groups. N Engl J Med 1980 3.15
10 Codon-improved Cre recombinase (iCre) expression in the mouse. Genesis 2002 2.92
11 Techniques: Recombinogenic engineering--new options for cloning and manipulating DNA. Trends Biochem Sci 2001 2.79
12 Immunochemical characterization of circulating parathyroid hormone-related protein in patients with humoral hypercalcemia of cancer. N Engl J Med 1990 2.76
13 The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program. Genes Dev 2001 2.76
14 The chromo shadow domain, a second chromo domain in heterochromatin-binding protein 1, HP1. Nucleic Acids Res 1995 2.59
15 RecE/RecT and Redalpha/Redbeta initiate double-stranded break repair by specifically interacting with their respective partners. Genes Dev 2000 2.39
16 Efficient and precise engineering of a 200 kb beta-globin human/bacterial artificial chromosome in E. coli DH10B using an inducible homologous recombination system. Gene Ther 1999 2.32
17 Identification of a novel 17,000-dalton parathyroid hormone-like adenylate cyclase-stimulating protein from a tumor associated with humoral hypercalcemia of malignancy. J Biol Chem 1987 2.30
18 Glucose stimulates human beta cell replication in vivo in islets transplanted into NOD-severe combined immunodeficiency (SCID) mice. Diabetologia 2010 2.26
19 Identification of a cDNA encoding a parathyroid hormone-like peptide from a human tumor associated with humoral hypercalcemia of malignancy. Proc Natl Acad Sci U S A 1988 2.20
20 Heterodimerization of the Drosophila ecdysone receptor with retinoid X receptor and ultraspiracle. Nature 1993 2.15
21 Ligand-regulated site-specific recombination. Proc Natl Acad Sci U S A 1995 2.14
22 Glucocorticoids are required for establishment and maintenance of an alteration in chromatin structure: induction leads to a reversible disruption of nucleosomes over an enhancer. EMBO J 1991 2.14
23 A CamKIIalpha iCre BAC allows brain-specific gene inactivation. Genesis 2001 2.08
24 Efficient FLP recombination in mouse ES cells and oocytes. Genesis 2001 1.94
25 Alteration of Cre recombinase site specificity by substrate-linked protein evolution. Nat Biotechnol 2001 1.92
26 Defining the roles of parathyroid hormone-related protein in normal physiology. Physiol Rev 1996 1.91
27 Point mutation of bacterial artificial chromosomes by ET recombination. EMBO Rep 2000 1.90
28 Camptothecin-induced in vivo topoisomerase I cleavages in the transcriptionally active tyrosine aminotransferase gene. Cell 1987 1.90
29 Different thermostabilities of FLP and Cre recombinases: implications for applied site-specific recombination. Nucleic Acids Res 1996 1.86
30 Hepatocyte growth factor overexpression in the islet of transgenic mice increases beta cell proliferation, enhances islet mass, and induces mild hypoglycemia. J Biol Chem 2000 1.85
31 NSD3, a new SET domain-containing gene, maps to 8p12 and is amplified in human breast cancer cell lines. Genomics 2001 1.85
32 Factors associated with humoral hypercalcemia of malignancy stimulate adenylate cyclase in osteoblastic cells. J Clin Invest 1983 1.84
33 Sensing X chromosome pairs before X inactivation via a novel X-pairing region of the Xic. Science 2007 1.83
34 Humoral hypercalcemia of cancer. Identification of a novel parathyroid hormone-like peptide. N Engl J Med 1988 1.82
35 Targeted expression of placental lactogen in the beta cells of transgenic mice results in beta cell proliferation, islet mass augmentation, and hypoglycemia. J Biol Chem 2000 1.82
36 Quantitative comparison of DNA looping in vitro and in vivo: chromatin increases effective DNA flexibility at short distances. EMBO J 1999 1.80
37 Simplified generation of targeting constructs using ET recombination. Nucleic Acids Res 1999 1.79
38 A simple assay to determine the functionality of Cre or FLP recombination targets in genomic manipulation constructs. Nucleic Acids Res 1996 1.78
39 Identification of adenylate cyclase-stimulating activity and cytochemical glucose-6-phosphate dehydrogenase-stimulating activity in extracts of tumors from patients with humoral hypercalcemia of malignancy. Proc Natl Acad Sci U S A 1983 1.75
40 Breast cancer incidence highest in the range of one species of house mouse, Mus domesticus. Br J Cancer 2000 1.73
41 Calcium homeostasis in immobilization: an example of resorptive hypercalciuria. N Engl J Med 1982 1.71
42 Quantitative bone histomorphometry in humoral hypercalcemia of malignancy: uncoupling of bone cell activity. J Clin Endocrinol Metab 1982 1.68
43 Independent regulation of cardiac Kv4.3 potassium channel expression by angiotensin II and phenylephrine. Circ Res 2001 1.64
44 Temporally and spatially regulated somatic mutagenesis in mice. Nucleic Acids Res 1998 1.62
45 Comparative kinetic analysis of FLP and cre recombinases: mathematical models for DNA binding and recombination. J Mol Biol 1998 1.56
46 N-terminal amino acid sequence of two novel tumor-derived adenylate cyclase-stimulating proteins: identification of parathyroid hormone-like and parathyroid hormone-unlike domains. Biochem Biophys Res Commun 1987 1.51
47 Parathyroid hormone-like proteins: biochemical responses and receptor interactions. Endocr Rev 1989 1.48
48 Chromatin structures of the rat tyrosine aminotransferase gene relate to the function of its cis-acting elements. Mol Cell Biol 1990 1.46
49 Transgenic overexpression of hepatocyte growth factor in the beta-cell markedly improves islet function and islet transplant outcomes in mice. Diabetes 2001 1.42
50 Distribution of alpha 1C-adrenergic receptor mRNA in adult rat tissues by RNase protection assay and comparison with alpha 1B and alpha 1D. Biochem Biophys Res Commun 1994 1.41
51 Elevations in circulating 1,25-dihydroxyvitamin D in three patients with lymphoma-associated hypercalcemia. J Clin Endocrinol Metab 1985 1.29
52 Evolution of the casein multigene family: conserved sequences in the 5' flanking and exon regions. Nucleic Acids Res 1986 1.28
53 The physiology of parathyroid hormone-related protein: an emerging role as a developmental factor. Annu Rev Physiol 1998 1.28
54 The chicken HPRT gene: a counter selectable marker for the DT40 cell line. Nucleic Acids Res 1999 1.27
55 Alpha1-adrenergic receptor subtype mRNAs are differentially regulated by alpha1-adrenergic and other hypertrophic stimuli in cardiac myocytes in culture and in vivo. Repression of alpha1B and alpha1D but induction of alpha1C. J Biol Chem 1996 1.27
56 Malignancy-associated hypercalcemia: evaluation with a cytochemical bioassay for parathyroid hormone. J Clin Endocrinol Metab 1981 1.24
57 Evolution of endothermy in fish: mapping physiological traits on a molecular phylogeny. Science 1993 1.21
58 Parathyroid hormone-related protein as a prohormone: posttranslational processing and receptor interactions. Endocr Rev 1994 1.18
59 ET-cloning: think recombination first. Genet Eng (N Y) 2000 1.18
60 Overexpression of parathyroid hormone-related protein in the pancreatic islets of transgenic mice causes islet hyperplasia, hyperinsulinemia, and hypoglycemia. J Biol Chem 1996 1.17
61 Parathyroid hormone-related protein and its receptors: nuclear functions and roles in the renal and cardiovascular systems, the placental trophoblasts and the pancreatic islets. Br J Pharmacol 2001 1.15
62 Papillary thyroid carcinoma metastatic to the pituitary gland. Thyroid 1999 1.12
63 Using beta-cell growth factors to enhance human pancreatic Islet transplantation. J Clin Endocrinol Metab 2001 1.11
64 At least three promoters direct expression of the mouse glucocorticoid receptor gene. Proc Natl Acad Sci U S A 1992 1.11
65 In vivo monitoring of a cAMP-stimulated DNA-binding activity. Genes Dev 1990 1.11
66 Identification of the functional domain in the transcription factor RTEF-1 that mediates alpha 1-adrenergic signaling in hypertrophied cardiac myocytes. J Biol Chem 2000 1.11
67 The identification of T-2 toxin and its association with a haemorrhagic syndrome in cattle. Vet Rec 1977 1.11
68 A parathyroid hormone-like protein from cultured human keratinocytes. Science 1986 1.09
69 Nucleotide sequences of bovine alpha S1- and kappa-casein cDNAs. Nucleic Acids Res 1984 1.08
70 BAC trimming: minimizing clone overlaps. Genomics 2000 1.07
71 Hypercalcemia in pheochromocytoma. Evidence for a novel mechanism. Ann Intern Med 1985 1.07
72 Opposing mitogenic and anti-mitogenic actions of parathyroid hormone-related protein in vascular smooth muscle cells: a critical role for nuclear targeting. Proc Natl Acad Sci U S A 1997 1.06
73 Identification of transcripts encoding a parathyroid hormone-like peptide in messenger RNAs from a variety of human and animal tumors associated with humoral hypercalcemia of malignancy. J Clin Invest 1988 1.06
74 Parathyroid hormone-related protein-(1--36) stimulates renal tubular calcium reabsorption in normal human volunteers: implications for the pathogenesis of humoral hypercalcemia of malignancy. J Clin Endocrinol Metab 2001 1.06
75 Chromatin structure analysis of the human c-fos promoter reveals a centrally positioned nucleosome. Chromosoma 1997 1.03
76 Dissociation of bone formation from resorption during 2-week treatment with human parathyroid hormone-related peptide-(1-36) in humans: potential as an anabolic therapy for osteoporosis. J Clin Endocrinol Metab 1998 1.02
77 Isolation and characterization of the bovine kappa-casein gene. Eur J Biochem 1988 0.99
78 Construction and identification by partial nucleotide sequence analysis of bovine casein and beta-lactoglobulin cDNA clones. DNA 1982 0.99
79 Excision of Ets by an inducible site-specific recombinase causes differentiation of Myb-Ets-transformed hematopoietic progenitors. Curr Biol 1996 0.98
80 Progressive pancreatic islet hyperplasia in the islet-targeted, parathyroid hormone-related protein-overexpressing mouse. Endocrinology 1998 0.97
81 Structural and physiologic characterization of the mid-region secretory species of parathyroid hormone-related protein. J Biol Chem 1996 0.97
82 Hypercalcemia in small cell carcinoma of the pancreas. Cancer 1984 0.96
83 Different positioning of the ligand-binding domain helix 12 and the F domain of the estrogen receptor accounts for functional differences between agonists and antagonists. EMBO J 1998 0.96
84 Parathyroid hormone-related protein-(1-36) is biologically active when administered subcutaneously to humans. J Clin Endocrinol Metab 1997 0.96
85 A novel and rapid method to generate single stranded DNA probes for genomic footprinting. Nucleic Acids Res 1988 0.95
86 Therapeutic controversies in primary hyperparathyroidism. J Clin Endocrinol Metab 1999 0.95
87 Biochemical and histomorphometric characterization of a rat model for humoral hypercalcemia of malignancy. Endocrinology 1984 0.94
88 FLP recombinase/estrogen receptor fusion proteins require the receptor D domain for responsiveness to antagonists, but not agonists. Mol Endocrinol 1997 0.94
89 Parathyroid hormone (PTH)-related protein(1-36) is equipotent to PTH(1-34) in humans. J Clin Endocrinol Metab 1996 0.94
90 Inducible expression based on regulated recombination: a single vector strategy for stable expression in cultured cells. Nucleic Acids Res 1998 0.93
91 Skin-derived fibroblasts respond to human parathyroid hormone-like adenylate cyclase-stimulating proteins. J Clin Endocrinol Metab 1987 0.91
92 Native and a synthetic analogue of the malignancy-associated parathyroid hormone-like protein have in vitro transforming growth factor-like properties. J Clin Invest 1989 0.91
93 Sensitivity of the parathyroid hormone-1,25-dihydroxyvitamin D axis to variations in calcium intake in patients with primary hyperparathyroidism. N Engl J Med 1985 0.91
94 Squamous carcinoma model of humoral hypercalcemia of malignancy. Endocrinology 1984 0.91
95 Analysis of PTHRP binding and signal transduction mechanisms in benign and malignant squamous cells. Am J Physiol 1992 0.90
96 Positive and negative discrimination of estrogen receptor agonists and antagonists using site-specific DNA recombinase fusion proteins. Mol Endocrinol 1998 0.87
97 Magnesium homeostasis following chemotherapy with cisplatin: a prospective study. Am J Obstet Gynecol 1985 0.87
98 Intraperitoneal free fatty acids induce severe hypocalcemia in rats: a model for the hypocalcemia of pancreatitis. J Bone Miner Res 1990 0.87
99 Nephrogenous cyclic AMP, adenylate cyclase-stimulating activity, and the humoral hypercalcemia of malignancy. Recent Prog Horm Res 1986 0.87
100 Midregion parathyroid hormone-related protein inhibits growth and invasion in vitro and tumorigenesis in vivo of human breast cancer cells. J Bone Miner Res 2001 0.86
101 Hypercalcemia in breast cancer. Reassessment of the mechanism. Am J Med 1987 0.86
102 The C-terminal region of PTHrP, in addition to the nuclear localization signal, is essential for the intracrine stimulation of proliferation in vascular smooth muscle cells. Endocrinology 2001 0.86
103 Creating a transloxation. Engineering interchromosomal translocations in the mouse. EMBO Rep 2000 0.86
104 Cell type-specific secretion of parathyroid hormone-related protein via the regulated versus the constitutive secretory pathway. J Biol Chem 1995 0.85
105 A pharmacological comparison of parathyroid hormone receptors in human bone and kidney. Endocrinology 1992 0.84
106 Primary hyperparathyroidism: preoperative localization using technetium-sestamibi scanning. J Clin Endocrinol Metab 1995 0.84
107 Parathyroid hormone-related protein modulates the effect of transforming growth factor-beta on deoxyribonucleic acid and collagen synthesis in fetal rat bone cells. Endocrinology 1989 0.84
108 Parathyroid hormone-related protein. Evidence for secretion of a novel mid-region fragment by three different cell types. J Biol Chem 1992 0.84
109 Complete sequence of the bovine beta-lactoglobulin cDNA. Nucleic Acids Res 1989 0.83
110 Corticotroph cell pituitary adenoma within an ovarian teratoma. A new cause of Cushing's syndrome. Am J Surg Pathol 1987 0.83
111 Systemic and acute administration of parathyroid hormone-related peptide(1-36) stimulates endogenous beta cell proliferation while preserving function in adult mice. Diabetologia 2011 0.83
112 Expression of parathyroid hormone-related protein in the rat glomerulus and tubule during recovery from renal ischemia. J Clin Invest 1993 0.83
113 Effect of parathyroid hormone-like peptides on 25-hydroxyvitamin D-1 alpha-hydroxylase activity in rodents. Am J Physiol 1990 0.82
114 Poorly differentiated ("insular") carcinoma of the thyroid gland: an aggressive subset of differentiated thyroid neoplasms. Surgery 1988 0.82
115 Synthetic and partially-purified adenylate cyclase-stimulating proteins from tumors associated with humoral hypercalcemia of malignancy inhibit phosphate transport in a PTH-responsive renal cell line. J Clin Endocrinol Metab 1988 0.82
116 Co-purification of transforming growth factor beta-like activity with PTH-like and bone-resorbing activities from a tumor associated with humoral hypercalcemia of malignancy. Endocrinology 1987 0.82
117 Preliminary characterization of circulating amino- and carboxy-terminal fragments of parathyroid hormone-related peptide in humoral hypercalcemia of malignancy. J Clin Endocrinol Metab 1992 0.81
118 Dose-response study of alendronate sodium for the treatment of cancer-associated hypercalcemia. J Clin Oncol 1993 0.81
119 Glycosylation of parathyroid hormone-related peptide secreted by human epidermal keratinocytes. J Clin Endocrinol Metab 1991 0.80
120 Identification of protein-DNA contacts with dimethyl sulfate. Methylation protection and methylation interference. Methods Mol Biol 1994 0.80
121 Complete nucleotide sequence of the bovine beta-casein gene. Aust J Biol Sci 1988 0.80
122 Expression and role of parathyroid hormone-related protein in human renal proximal tubule cells during recovery from ATP depletion. J Am Soc Nephrol 1999 0.79
123 Characterization of canine renal receptors for the parathyroid hormone-like protein associated with humoral hypercalcemia of malignancy. J Biol Chem 1989 0.79
124 Amino-terminal parathyroid hormone-related protein: specific binding and cytosolic calcium responses in rat insulinoma cells. Endocrinology 1993 0.79
125 Cross-talk modulation of signal transduction pathways: two mechanisms are involved in the control of tyrosine aminotransferase gene expression by phorbol esters. Mol Endocrinol 1994 0.79
126 Therapy of malignancy-associated hypercalcemia: 1983. Am J Med 1983 0.79
127 Rapid localization of a gene within BACs and PACs. Biotechniques 2002 0.78
128 Parathyroid hormone-related protein as a cardiovascular regulatory peptide. Endocrinology 1996 0.78
129 Hypocalcemia associated with calcium-soap formation in a patient with a pancreatic fistula. N Engl J Med 1986 0.78
130 The regulation of renal calcium excretion: an approach to hypercalciuria. Annu Rev Med 1981 0.78
131 Humoral hypercalcemia of malignancy. Ann Intern Med 1988 0.78
132 Parathyroid hormone-related protein detection and interaction with NO and cyclic AMP in the renovascular system. Kidney Int 1996 0.78
133 Transfection and overexpression of the calcium binding protein calbindin-D28k results in a stimulatory effect on insulin synthesis in a rat beta cell line (RIN 1046-38). Proc Natl Acad Sci U S A 1997 0.78
134 Identification of protein-DNA contacts with dimethyl sulfate. Methylation protection and methylation interference. Methods Mol Biol 2001 0.77
135 Parathyroid hormone-related peptide--a smooth muscle tone and proliferation regulatory protein. Curr Opin Nephrol Hypertens 1998 0.77
136 Detection of the hypercalcemic hormone of malignancy in an adrenal cortical carcinoma. J Urol 1986 0.77
137 The carboxy-terminus of parathyroid hormone--inert or invaluable? Endocrinology 1995 0.77
138 Parathyroid carcinoma arising from parathyroid hyperplasia: autoinfarction following intravenous treatment with pamidronate. Am J Med 1994 0.77
139 Self-deleting suicide vectors (SDSV): selective killing of p53-deficient cancer cells. Cancer Res 2001 0.77
140 Analysis of DNaseI hypersensitive sites in chromatin by cleavage in permeabilized cells. Methods Mol Biol 1999 0.77
141 Hypocalcemia-induced pustular psoriasis of von Zumbusch. New experience with an old syndrome. Ann Intern Med 1984 0.77
142 Characterization of a parathyroid hormonelike peptide secreted by human keratinocytes. Ann N Y Acad Sci 1988 0.76
143 Is there a role for parathyroid hormone in humoral hypercalcemia of malignancy? Miner Electrolyte Metab 1983 0.76
144 Renovascular parathyroid hormone-related protein in spontaneously hypertensive rats: dilator or trophic factor? Kidney Int Suppl 1998 0.75
145 Hypercalcemia associated with gynecologic malignancies: biochemical characterization. Cancer 1982 0.75
146 Parathyroid hormone-related protein a peptide of diverse physiologic functions. Trends Endocrinol Metab 1993 0.75
147 Parathyroid hormone-related protein in rat penis: expression, localization, and effect on cavernosal pressure. Endocrinology 1999 0.75
148 Interspecies comparison of renal cortical receptors for parathyroid hormone and parathyroid hormone-related protein. J Bone Miner Res 1991 0.75
149 The alkaloids of Rauwolfia rosea K. Schum. (African Rauwolfia species--8). Planta Med 1967 0.75
150 Parathyroid-hormone-related protein: a previously unrecognized renal vasodilator. Nephrol Dial Transplant 1995 0.75
151 The alkaloids of Rauwolfia cumminsii Stapf (African Rauwolfia species. IX). Planta Med 1967 0.75
152 Calcium metabolism without anguish. Understanding the body's homeostatic 'black box'. Postgrad Med 1985 0.75
153 Noneffect of electronegative gases on pulsed laser-induced optical surface damage thresholds. Appl Opt 1984 0.75
154 Surface charging in laser damage to dielectric surfaces and thin films. Appl Opt 1987 0.75
155 Hypercalcaemia complicating acute myelogenous leukaemia: a syndrome of multiple aetiologies. Br J Haematol 1983 0.75
156 The assay of Rauwolfia cumminsii by quantitative thin-layer chromatography. (African Rauwolfia species-XII). Planta Med 1968 0.75
157 Quantitative evaluation of anticalciuretic effects of synthetic parathyroid hormonelike peptides. J Bone Miner Res 1990 0.75
158 Laser damage test results on Balzers round-robin thin film samples. Appl Opt 1984 0.75
159 Laser-induced damage: an introduction. Appl Opt 1984 0.75
160 African rauwolfia species. V. The structure of the root and stem of Rauwolfia rosea K. Schum. Planta Med 1967 0.75
161 Endocrinology clinical case seminars: a 23-year-old man with hypercalcemia, anemia, and weight loss. J Clin Endocrinol Metab 1994 0.75
162 The assay and stability of chlorpropamide in solid dispersion with urea. J Pharm Pharmacol 1979 0.75
163 Letter: Scrotal asymmetry: an appendix. Nature 1976 0.75
164 The structure of the root and stem of Rauwolfia cumminsii stapf. (African rauwolfia species--X). Planta Med 1967 0.75
165 Laser-induced particle emission as a precursor to laser damage. Appl Opt 1988 0.75
166 Parathyroid hormone-related protein in the pancreatic islet and the cardiovascular system. Recent Prog Horm Res 1998 0.75
167 Charged particle emission related to laser damage. Appl Opt 1986 0.75
168 Two species of adenylate cyclase-stimulating activity in a murine squamous carcinoma model of humoral hypercalcemia of malignancy. Endocrinology 1986 0.75
169 The Kw recombinase, an integrase from Kluyveromyces waltii. Eur J Biochem 1997 0.75
170 1.06-microm laser damage of thin film optical coatings: a round-robin experiment involving various pulse lengths and beam diameters. Appl Opt 1984 0.75