Published in Genes Dev on November 15, 2001
Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II. Mol Cell Biol (2003) 6.79
The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4. EMBO J (2001) 5.34
Deconstructing repression: evolving models of co-repressor action. Nat Rev Genet (2010) 3.29
Mechanism of the eukaryotic chaperonin: protein folding in the chamber of secrets. Trends Cell Biol (2004) 3.18
Protein pathway and complex clustering of correlated mRNA and protein expression analyses in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2003) 2.73
Dimethylation of H3K4 by Set1 recruits the Set3 histone deacetylase complex to 5' transcribed regions. Cell (2009) 2.62
The cyclophilins. Genome Biol (2005) 2.58
Yeast enhancer of polycomb defines global Esa1-dependent acetylation of chromatin. Genes Dev (2003) 2.30
The histone 3 lysine 36 methyltransferase, SET2, is involved in transcriptional elongation. Nucleic Acids Res (2003) 2.20
Hdac3 is essential for the maintenance of chromatin structure and genome stability. Cancer Cell (2010) 2.20
The N-CoR/histone deacetylase 3 complex is required for repression by thyroid hormone receptor. Mol Cell Biol (2003) 2.15
Haploinsufficiency-based large-scale forward genetic analysis of filamentous growth in the diploid human fungal pathogen C.albicans. EMBO J (2003) 2.11
Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly made proteins with complex topologies. Nat Struct Mol Biol (2008) 2.07
Sum1 and Ndt80 proteins compete for binding to middle sporulation element sequences that control meiotic gene expression. Mol Cell Biol (2003) 1.90
Hierarchical modularity and the evolution of genetic interactomes across species. Mol Cell (2012) 1.88
H2B ubiquitin protease Ubp8 and Sgf11 constitute a discrete functional module within the Saccharomyces cerevisiae SAGA complex. Mol Cell Biol (2005) 1.82
Histone-modifying complexes regulate gene expression pertinent to the differentiation of the protozoan parasite Toxoplasma gondii. Mol Cell Biol (2005) 1.72
Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment. Genome Biol (2008) 1.65
The interaction network of the chaperonin CCT. EMBO J (2008) 1.63
A SANT motif in the SMRT corepressor interprets the histone code and promotes histone deacetylation. EMBO J (2003) 1.62
Transcription of two long noncoding RNAs mediates mating-type control of gametogenesis in budding yeast. Cell (2012) 1.61
Set3 HDAC mediates effects of overlapping noncoding transcription on gene induction kinetics. Cell (2012) 1.61
MLL5 contributes to hematopoietic stem cell fitness and homeostasis. Blood (2008) 1.59
Assembly of the SMRT-histone deacetylase 3 repression complex requires the TCP-1 ring complex. Genes Dev (2002) 1.53
Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages. Proc Natl Acad Sci U S A (2012) 1.53
Reading and function of a histone code involved in targeting corepressor complexes for repression. Mol Cell Biol (2005) 1.52
Comparative analysis of SET domain proteins in maize and Arabidopsis reveals multiple duplications preceding the divergence of monocots and dicots. Plant Physiol (2003) 1.47
Set1 is required for meiotic S-phase onset, double-strand break formation and middle gene expression. EMBO J (2004) 1.46
Rfm1, a novel tethering factor required to recruit the Hst1 histone deacetylase for repression of middle sporulation genes. Mol Cell Biol (2003) 1.44
H3 lysine 4 is acetylated at active gene promoters and is regulated by H3 lysine 4 methylation. PLoS Genet (2011) 1.43
The Hos2 Histone Deacetylase Controls Ustilago maydis Virulence through Direct Regulation of Mating-Type Genes. PLoS Pathog (2015) 1.38
Structure of the sporulation-specific transcription factor Ndt80 bound to DNA. EMBO J (2002) 1.31
Phosphorylation and maximal activity of Saccharomyces cerevisiae meiosis-specific transcription factor Ndt80 is dependent on Ime2. Mol Cell Biol (2002) 1.26
Host factors that affect Ty3 retrotransposition in Saccharomyces cerevisiae. Genetics (2004) 1.19
Defining the budding yeast chromatin-associated interactome. Mol Syst Biol (2010) 1.19
Emerging roles of the corepressors NCoR1 and SMRT in homeostasis. Genes Dev (2013) 1.18
The Set3/Hos2 histone deacetylase complex attenuates cAMP/PKA signaling to regulate morphogenesis and virulence of Candida albicans. PLoS Pathog (2010) 1.16
Transcriptional loops meet chromatin: a dual-layer network controls white-opaque switching in Candida albicans. Mol Microbiol (2009) 1.16
Molecular basis for chromatin binding and regulation of MLL5. Proc Natl Acad Sci U S A (2013) 1.15
Demethylation of histone H3K36 and H3K9 by Rph1: a vestige of an H3K9 methylation system in Saccharomyces cerevisiae? Mol Cell Biol (2007) 1.15
Hijacked in cancer: the KMT2 (MLL) family of methyltransferases. Nat Rev Cancer (2015) 1.12
The role of cotranscriptional histone methylations. Cold Spring Harb Symp Quant Biol (2011) 1.11
The Schizosaccharomyces pombe JmjC-protein, Msc1, prevents H2A.Z localization in centromeric and subtelomeric chromatin domains. PLoS Genet (2009) 1.10
Substitution as a mechanism for genetic robustness: the duplicated deacetylases Hst1p and Sir2p in Saccharomyces cerevisiae. PLoS Genet (2007) 1.08
Genome-wide screen for inositol auxotrophy in Saccharomyces cerevisiae implicates lipid metabolism in stress response signaling. Mol Genet Genomics (2010) 1.07
A histone deacetylase adjusts transcription kinetics at coding sequences during Candida albicans morphogenesis. PLoS Genet (2012) 1.05
Two novel methyltransferases acting upon eukaryotic elongation factor 1A in Saccharomyces cerevisiae. Arch Biochem Biophys (2010) 1.04
Hos2 and Set3 promote integration of Ty1 retrotransposons at tRNA genes in Saccharomyces cerevisiae. Genetics (2006) 1.03
The tig1 histone deacetylase complex regulates infectious growth in the rice blast fungus Magnaporthe oryzae. Plant Cell (2010) 1.03
Calcineurin regulation in fungi and beyond. Eukaryot Cell (2007) 1.02
The yeast SR-like protein Npl3 links chromatin modification to mRNA processing. PLoS Genet (2012) 1.01
Hos2p/Set3p deacetylase complex signals secretory stress through the Mpk1p cell integrity pathway. Eukaryot Cell (2008) 1.00
Endogenous transcription at the centromere facilitates centromere activity in budding yeast. Curr Biol (2011) 1.00
Sum1p, the origin recognition complex, and the spreading of a promoter-specific repressor in Saccharomyces cerevisiae. Mol Cell Biol (2005) 0.99
FKBP12 controls aspartate pathway flux in Saccharomyces cerevisiae to prevent toxic intermediate accumulation. Eukaryot Cell (2004) 0.98
Identification and comparative analysis of the peptidyl-prolyl cis/trans isomerase repertoires of H. sapiens, D. melanogaster, C. elegans, S. cerevisiae and Sz. pombe. Comp Funct Genomics (2005) 0.97
UpSET recruits HDAC complexes and restricts chromatin accessibility and acetylation at promoter regions. Cell (2012) 0.96
Cyclophilin A is localized to the nucleus and controls meiosis in Saccharomyces cerevisiae. Eukaryot Cell (2005) 0.95
Transducin beta-like gene FTL1 is essential for pathogenesis in Fusarium graminearum. Eukaryot Cell (2009) 0.94
Swapping the gene-specific and regional silencing specificities of the Hst1 and Sir2 histone deacetylases. Mol Cell Biol (2007) 0.94
Interplay between chromatin and trans-acting factors on the IME2 promoter upon induction of the gene at the onset of meiosis. Mol Cell Biol (2006) 0.93
Genetic identification of factors that modulate ribosomal DNA transcription in Saccharomyces cerevisiae. Genetics (2009) 0.93
Genetic analysis implicates the Set3/Hos2 histone deacetylase in the deposition and remodeling of nucleosomes containing H2A.Z. Genetics (2011) 0.93
The histone deacetylase Hos2 forms an Hsp42-dependent cytoplasmic granule in quiescent yeast cells. Mol Biol Cell (2012) 0.91
Stb3 plays a role in the glucose-induced transition from quiescence to growth in Saccharomyces cerevisiae. Genetics (2010) 0.89
Mll5 is required for normal spermatogenesis. PLoS One (2011) 0.89
A histone deacetylase complex mediates biofilm dispersal and drug resistance in Candida albicans. MBio (2014) 0.87
Identification and comparative analysis of sixteen fungal peptidyl-prolyl cis/trans isomerase repertoires. BMC Genomics (2006) 0.87
Combination of genomic approaches with functional genetic experiments reveals two modes of repression of yeast middle-phase meiosis genes. BMC Genomics (2010) 0.86
The SET domain protein, Set3p, promotes the reliable execution of cytokinesis in Schizosaccharomyces pombe. PLoS One (2012) 0.85
Prolyl isomerases in gene transcription. Biochim Biophys Acta (2014) 0.85
Histone acetylation in fungal pathogens of plants. Plant Pathol J (2014) 0.84
Evolution of SET-domain protein families in the unicellular and multicellular Ascomycota fungi. BMC Evol Biol (2008) 0.84
Two histone deacetylases, FfHda1 and FfHda2, are important for Fusarium fujikuroi secondary metabolism and virulence. Appl Environ Microbiol (2013) 0.82
H3K4 methyltransferase Set1 is involved in maintenance of ergosterol homeostasis and resistance to Brefeldin A. Proc Natl Acad Sci U S A (2013) 0.82
Genome-wide identification of genes involved in the positive and negative regulation of acetic acid-induced programmed cell death in Saccharomyces cerevisiae. BMC Genomics (2013) 0.82
Set1/COMPASS and Mediator are repurposed to promote epigenetic transcriptional memory. Elife (2016) 0.81
NuA4 initiates dynamic histone H4 acetylation to promote high-fidelity sister chromatid recombination at postreplication gaps. Mol Cell (2014) 0.81
Regulating repression: roles for the sir4 N-terminus in linker DNA protection and stabilization of epigenetic states. PLoS Genet (2012) 0.81
Bypassing the requirement for an essential MYST acetyltransferase. Genetics (2014) 0.80
The mating-type-related bias of gene conversion in Schizosaccharomyces pombe. Genetics (2008) 0.80
MOfinder: a novel algorithm for detecting overlapping modules from protein-protein interaction network. J Biomed Biotechnol (2012) 0.80
Sporulation genes associated with sporulation efficiency in natural isolates of yeast. PLoS One (2013) 0.80
Global reorganization of budding yeast chromosome conformation in different physiological conditions. J Cell Biol (2016) 0.80
Chromatin-mediated Candida albicans virulence. Biochim Biophys Acta (2011) 0.78
Identifying responsive modules by mathematical programming: an application to budding yeast cell cycle. PLoS One (2012) 0.77
Set3 contributes to heterochromatin integrity by promoting transcription of subunits of Clr4-Rik1-Cul4 histone methyltransferase complex in fission yeast. Sci Rep (2016) 0.77
The Set3 Complex Antagonizes the MYST Acetyltransferase Esa1 in the DNA Damage Response. Mol Cell Biol (2015) 0.76
Multiple MAPK cascades regulate the transcription of IME1, the master transcriptional activator of meiosis in Saccharomyces cerevisiae. PLoS One (2013) 0.76
UpSET-ting the balance: modulating open chromatin features in metazoan genomes. Fly (Austin) (2013) 0.76
SUB1 Plays a Negative Role during Starvation Induced Sporulation Program in Saccharomyces cerevisiae. PLoS One (2015) 0.76
The Human Mixed Lineage Leukemia 5 (MLL5), a Sequentially and Structurally Divergent SET Domain-Containing Protein with No Intrinsic Catalytic Activity. PLoS One (2016) 0.75
Different Toxicity Mechanisms for Citrinin and Ochratoxin A Revealed by Transcriptomic Analysis in Yeast. Toxins (Basel) (2016) 0.75
Crystallization and preliminary crystallographic studies of the NAD+-dependent deacetylase HST1 from Saccharomyces cerevisiae. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.75
upSET, the Drosophila Homologue of SET3, Is Required for Viability and the Proper Balance of Active and Repressive Chromatin Marks. G3 (Bethesda) (2017) 0.75
GSF2 deletion increases lactic acid production by alleviating glucose repression in Saccharomyces cerevisiae. Sci Rep (2016) 0.75
Structural Insight into Recognition of Methylated Histone H3K4 by Set3. J Mol Biol (2016) 0.75
Setd5 is essential for mammalian development and co-transcriptional regulation of histone acetylation. Development (2016) 0.75
Modulation of gene expression dynamics by co-transcriptional histone methylations. Exp Mol Med (2017) 0.75
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res (1997) 665.31
The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res (1997) 175.36
A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature (2000) 47.15
Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal Chem (1996) 45.70
The transcriptional program of sporulation in budding yeast. Science (1998) 37.23
A comprehensive two-hybrid analysis to explore the yeast protein interactome. Proc Natl Acad Sci U S A (2001) 33.71
A generic protein purification method for protein complex characterization and proteome exploration. Nat Biotechnol (1999) 25.13
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature (2000) 20.54
A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids. Anal Biochem (1984) 19.70
Regulation of chromatin structure by site-specific histone H3 methyltransferases. Nature (2000) 18.26
A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p. Science (1996) 12.64
Linking genome and proteome by mass spectrometry: large-scale identification of yeast proteins from two dimensional gels. Proc Natl Acad Sci U S A (1996) 8.10
The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases. Proc Natl Acad Sci U S A (2000) 7.92
The PHD finger: implications for chromatin-mediated transcriptional regulation. Trends Biochem Sci (1995) 6.97
Altered Hox expression and segmental identity in Mll-mutant mice. Nature (1995) 6.60
A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family. Proc Natl Acad Sci U S A (2000) 6.49
HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription. Proc Natl Acad Sci U S A (1996) 5.61
Repression domain of the yeast global repressor Tup1 interacts directly with histones H3 and H4. Genes Dev (1996) 5.58
The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability. Genes Dev (1995) 5.55
The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4. EMBO J (2001) 5.34
Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3. EMBO J (2000) 5.22
The core meiotic transcriptome in budding yeasts. Nat Genet (2000) 4.64
The protein encoded by the Drosophila position-effect variegation suppressor gene Su(var)3-9 combines domains of antagonistic regulators of homeotic gene complexes. EMBO J (1994) 4.36
A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness. Genes Dev (2000) 4.23
The ankyrin repeat: a diversity of interactions on a common structural framework. Trends Biochem Sci (1999) 4.14
A biological atlas of functional maps. Cell (2001) 3.98
Polycombing the genome: PcG, trxG, and chromatin silencing. Cell (1998) 3.97
A role for histone deacetylase activity in HDAC1-mediated transcriptional repression. Proc Natl Acad Sci U S A (1998) 3.85
Sum1 and Hst1 repress middle sporulation-specific gene expression during mitosis in Saccharomyces cerevisiae. EMBO J (1999) 3.65
Gametogenesis in yeast is regulated by a transcriptional cascade dependent on Ndt80. Mol Cell (1998) 3.58
The SANT domain: a putative DNA-binding domain in the SWI-SNF and ADA complexes, the transcriptional co-repressor N-CoR and TFIIIB. Trends Biochem Sci (1996) 3.55
SET1, a yeast member of the trithorax family, functions in transcriptional silencing and diverse cellular processes. Mol Biol Cell (1997) 3.33
Association of SET domain and myotubularin-related proteins modulates growth control. Nat Genet (1998) 3.32
The Drosophila Polycomb-group gene Enhancer of zeste contains a region with sequence similarity to trithorax. Mol Cell Biol (1993) 2.85
WHSC1, a 90 kb SET domain-containing gene, expressed in early development and homologous to a Drosophila dysmorphy gene maps in the Wolf-Hirschhorn syndrome critical region and is fused to IgH in t(4;14) multiple myeloma. Hum Mol Genet (1998) 2.77
Mutations in the fission yeast silencing factors clr4+ and rik1+ disrupt the localisation of the chromo domain protein Swi6p and impair centromere function. J Cell Sci (1996) 2.73
Solution structure of the PHD domain from the KAP-1 corepressor: structural determinants for PHD, RING and LIM zinc-binding domains. EMBO J (2001) 2.54
The C-terminal SET domains of ALL-1 and TRITHORAX interact with the INI1 and SNR1 proteins, components of the SWI/SNF complex. Proc Natl Acad Sci U S A (1998) 2.52
NDT80 and the meiotic recombination checkpoint regulate expression of middle sporulation-specific genes in Saccharomyces cerevisiae. Mol Cell Biol (1998) 2.47
Positive control of sporulation-specific genes by the IME1 and IME2 products in Saccharomyces cerevisiae. Mol Cell Biol (1990) 2.44
The Groucho/transducin-like enhancer of split transcriptional repressors interact with the genetically defined amino-terminal silencing domain of histone H3. J Biol Chem (1997) 2.26
The chromo and SET domains of the Clr4 protein are essential for silencing in fission yeast. Nat Genet (1998) 2.25
Beyond the nucleosome: epigenetic aspects of position-effect variegation in Drosophila. Cell (1998) 2.24
Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators. EMBO J (1998) 2.20
New constructs and strategies for efficient PCR-based gene manipulations in yeast. Yeast (1998) 2.05
Flow cytometric analysis of DNA content in budding yeast. Methods Enzymol (1997) 2.03
Structure of the PHD zinc finger from human Williams-Beuren syndrome transcription factor. J Mol Biol (2000) 1.95
The Drosophila ash1 gene product, which is localized at specific sites on polytene chromosomes, contains a SET domain and a PHD finger. Genetics (1996) 1.89
Skp1 forms multiple protein complexes, including RAVE, a regulator of V-ATPase assembly. Nat Cell Biol (2001) 1.89
The Drosophila trithorax proteins contain a novel variant of the nuclear receptor type DNA binding domain and an ancient conserved motif found in other chromosomal proteins. Mech Dev (1995) 1.87
NSD3, a new SET domain-containing gene, maps to 8p12 and is amplified in human breast cancer cell lines. Genomics (2001) 1.85
Parameters affecting lithium acetate-mediated transformation of Saccharomyces cerevisiae and development of a rapid and simplified procedure. Curr Genet (1993) 1.64
Conversion of a gene-specific repressor to a regional silencer. Genes Dev (2001) 1.64
Cyclophilin A and Ess1 interact with and regulate silencing by the Sin3-Rpd3 histone deacetylase. EMBO J (2000) 1.54
Protein folding: versatility of the cytosolic chaperonin TRiC/CCT. Curr Biol (2000) 1.50
Purification and biochemical properties of yeast SWI/SNF complex. Methods Enzymol (1999) 1.41
The pachytene checkpoint in Saccharomyces cerevisiae requires the Sum1 transcriptional repressor. EMBO J (2000) 1.30
Functional dissection of the B" component of RNA polymerase III transcription factor IIIB: a scaffolding protein with multiple roles in assembly and initiation of transcription. Mol Cell Biol (1997) 1.28
Self-association of the SET domains of human ALL-1 and of Drosophila TRITHORAX and ASH1 proteins. Oncogene (2000) 1.25
Sif2p interacts with Sir4p amino-terminal domain and antagonizes telomeric silencing in yeast. Curr Biol (1998) 1.17
trithorax and the regulation of homeotic gene expression in Drosophila: a historical perspective. Int J Dev Biol (1998) 0.96
Genomic disruption of six budding yeast genes gives one drastic example of phenotype strain-dependence. Yeast (1998) 0.86
A strategy for the characterization of protein interaction networks by mass spectrometry. Biochem Soc Trans (1999) 0.86
Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal Chem (1996) 45.70
A generic protein purification method for protein complex characterization and proteome exploration. Nat Biotechnol (1999) 25.13
The tandem affinity purification (TAP) method: a general procedure of protein complex purification. Methods (2001) 15.37
A new logic for DNA engineering using recombination in Escherichia coli. Nat Genet (1998) 15.27
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex. Cell (1996) 12.07
IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation. Science (1997) 11.89
High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP. Nat Genet (2000) 11.80
Reverse transcriptase motifs in the catalytic subunit of telomerase. Science (1997) 10.10
Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry. Nature (1996) 9.36
The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases. Cell (1997) 8.94
Linking genome and proteome by mass spectrometry: large-scale identification of yeast proteins from two dimensional gels. Proc Natl Acad Sci U S A (1996) 8.10
Error-tolerant identification of peptides in sequence databases by peptide sequence tags. Anal Chem (1994) 7.04
Positive feedback in eukaryotic gene networks: cell differentiation by graded to binary response conversion. EMBO J (2001) 7.03
The PHD finger: implications for chromatin-mediated transcriptional regulation. Trends Biochem Sci (1995) 6.97
Rapid modification of bacterial artificial chromosomes by ET-recombination. Nucleic Acids Res (1999) 6.85
Glucosylation of Rho proteins by Clostridium difficile toxin B. Nature (1995) 6.08
Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex. Cell (1999) 5.98
TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleus. Mol Cell (1998) 5.85
Cohesin's binding to chromosomes depends on a separate complex consisting of Scc2 and Scc4 proteins. Mol Cell (2000) 5.49
The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4. EMBO J (2001) 5.34
Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity. Cell (2001) 5.33
An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast. Cell (1998) 5.29
Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells. Nature (1997) 5.08
A Sm-like protein complex that participates in mRNA degradation. EMBO J (2000) 5.08
Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome. Science (2001) 4.82
Phosphatidylinositol-3-OH kinases are Rab5 effectors. Nat Cell Biol (1999) 4.76
DNA cloning by homologous recombination in Escherichia coli. Nat Biotechnol (2000) 4.75
A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function. Cell (1997) 4.68
FLICE is activated by association with the CD95 death-inducing signaling complex (DISC). EMBO J (1997) 4.56
A novel complex of nucleoporins, which includes Sec13p and a Sec13p homolog, is essential for normal nuclear pores. Cell (1996) 4.37
A common core RNP structure shared between the small nucleoar box C/D RNPs and the spliceosomal U4 snRNP. Cell (2000) 4.33
Chromatin-remodelling factor CHRAC contains the ATPases ISWI and topoisomerase II. Nature (1997) 4.28
Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34. Genes Dev (1999) 4.17
Improved properties of FLP recombinase evolved by cycling mutagenesis. Nat Biotechnol (1998) 4.14
Lipid rafts function in biosynthetic delivery of proteins to the cell surface in yeast. Proc Natl Acad Sci U S A (2000) 4.14
REF, an evolutionary conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export. RNA (2000) 4.10
mRNA silencing in erythroid differentiation: hnRNP K and hnRNP E1 regulate 15-lipoxygenase translation from the 3' end. Cell (1997) 4.03
The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates. RNA (2000) 3.96
FYVE fingers bind PtdIns(3)P. Nature (1998) 3.91
A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro. EMBO J (1999) 3.80
Spindle checkpoint protein Xmad1 recruits Xmad2 to unattached kinetochores. J Cell Biol (1998) 3.77
Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin. EMBO J (1999) 3.68
The SANT domain: a putative DNA-binding domain in the SWI-SNF and ADA complexes, the transcriptional co-repressor N-CoR and TFIIIB. Trends Biochem Sci (1996) 3.55
Gln 63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor-1. Nature (1997) 3.53
Endosomal localization of the autoantigen EEA1 is mediated by a zinc-binding FYVE finger. J Biol Chem (1996) 3.53
Involvement of U6 snRNA in 5' splice site selection. Science (1993) 3.51
Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A. Mol Cell (1999) 3.46
Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins. Science (1998) 3.38
Accurate processing of a eukaryotic precursor ribosomal RNA by ribonuclease MRP in vitro. Science (1996) 3.35
Biochemical evaluation of patients with cancer-associated hypercalcemia: evidence for humoral and nonhumoral groups. N Engl J Med (1980) 3.15
The POP1 gene encodes a protein component common to the RNase MRP and RNase P ribonucleoproteins. Genes Dev (1994) 3.12
The enterotoxin from Clostridium difficile (ToxA) monoglucosylates the Rho proteins. J Biol Chem (1995) 3.02
The budding yeast proteins Spc24p and Spc25p interact with Ndc80p and Nuf2p at the kinetochore and are important for kinetochore clustering and checkpoint control. EMBO J (2001) 3.02
TPX2, A novel xenopus MAP involved in spindle pole organization. J Cell Biol (2000) 3.01
The apoptosis-promoting factor TIA-1 is a regulator of alternative pre-mRNA splicing. Mol Cell (2000) 2.97
Rabenosyn-5, a novel Rab5 effector, is complexed with hVPS45 and recruited to endosomes through a FYVE finger domain. J Cell Biol (2000) 2.97
Gemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems. J Cell Biol (1999) 2.93
Codon-improved Cre recombinase (iCre) expression in the mouse. Genesis (2002) 2.92
The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor. Genes Dev (2001) 2.91
Nuclear pore proteins are involved in the biogenesis of functional tRNA. EMBO J (1996) 2.90
PHAX, a mediator of U snRNA nuclear export whose activity is regulated by phosphorylation. Cell (2000) 2.88
Structural basis for activation of the titin kinase domain during myofibrillogenesis. Nature (1998) 2.80
Techniques: Recombinogenic engineering--new options for cloning and manipulating DNA. Trends Biochem Sci (2001) 2.79
Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli. J Cell Biol (2000) 2.78
Immunochemical characterization of circulating parathyroid hormone-related protein in patients with humoral hypercalcemia of cancer. N Engl J Med (1990) 2.76
The yeast POP2 gene encodes a nuclease involved in mRNA deadenylation. Nucleic Acids Res (2001) 2.76
The DExH/D box protein HEL/UAP56 is essential for mRNA nuclear export in Drosophila. Curr Biol (2001) 2.70
IkappaB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex. Mol Cell Biol (1999) 2.68
Charting the proteomes of organisms with unsequenced genomes by MALDI-quadrupole time-of-flight mass spectrometry and BLAST homology searching. Anal Chem (2001) 2.65
A protein complex containing Inscuteable and the Galpha-binding protein Pins orients asymmetric cell divisions in Drosophila. Curr Biol (2000) 2.64
The chromo shadow domain, a second chromo domain in heterochromatin-binding protein 1, HP1. Nucleic Acids Res (1995) 2.59
Dbp5, a DEAD-box protein required for mRNA export, is recruited to the cytoplasmic fibrils of nuclear pore complex via a conserved interaction with CAN/Nup159p. EMBO J (1999) 2.58
A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins. RNA (1998) 2.55
RecE/RecT and Redalpha/Redbeta initiate double-stranded break repair by specifically interacting with their respective partners. Genes Dev (2000) 2.39
RanGTP-regulated interactions of CRM1 with nucleoporins and a shuttling DEAD-box helicase. Mol Cell Biol (1999) 2.37
Functional interaction of Nic96p with a core nucleoporin complex consisting of Nsp1p, Nup49p and a novel protein Nup57p. EMBO J (1995) 2.35
Rapid 'de novo' peptide sequencing by a combination of nanoelectrospray, isotopic labeling and a quadrupole/time-of-flight mass spectrometer. Rapid Commun Mass Spectrom (1997) 2.34