Published in Cell on June 06, 1986
Some recent advances in the chemistry and biology of transforming growth factor-beta. J Cell Biol (1987) 5.25
Key features of heat shock regulatory elements. Mol Cell Biol (1988) 4.54
Purification and characterization of a heat-shock element binding protein from yeast. EMBO J (1987) 4.43
Multiple cis regulatory elements for maximal expression of the cauliflower mosaic virus 35S promoter in transgenic plants. Plant Cell (1989) 3.54
Heat-inducible human factor that binds to a human hsp70 promoter. Mol Cell Biol (1987) 3.52
A 22 bp cis-acting element is necessary and sufficient for the induction of the yeast KAR2 (BiP) gene by unfolded proteins. EMBO J (1992) 3.48
A cellular transcription factor E4F1 interacts with an E1a-inducible enhancer and mediates constitutive enhancer function in vitro. EMBO J (1987) 3.45
Synergistic action of the glucocorticoid receptor with transcription factors. EMBO J (1988) 3.34
A survey of 178 NF-Y binding CCAAT boxes. Nucleic Acids Res (1998) 3.20
A human cytomegalovirus early gene has three inducible promoters that are regulated differentially at various times after infection. J Virol (1989) 2.70
Xenopus cytoskeletal actin and human c-fos gene promoters share a conserved protein-binding site. EMBO J (1987) 2.69
Conserved major histocompatibility complex class II boxes--X and Y--are transcriptional control elements and specifically bind nuclear proteins. Proc Natl Acad Sci U S A (1987) 2.55
(CT)n (GA)n repeats and heat shock elements have distinct roles in chromatin structure and transcriptional activation of the Drosophila hsp26 gene. Mol Cell Biol (1993) 2.52
DNA looping and Sp1 multimer links: a mechanism for transcriptional synergism and enhancement. Proc Natl Acad Sci U S A (1991) 2.51
A germline transformation analysis reveals flexibility in the organization of heat shock consensus elements. Nucleic Acids Res (1987) 2.48
Xenopus Y-box transcription factors: molecular cloning, functional analysis and developmental regulation. Proc Natl Acad Sci U S A (1990) 2.21
Two transcriptional activators, CCAAT-box-binding transcription factor and heat shock transcription factor, interact with a human hsp70 gene promoter. Mol Cell Biol (1987) 2.17
Conserved sequences and transcription of the hsp70 gene family in Trypanosoma brucei. Mol Cell Biol (1986) 2.11
Multiple 5'-flanking regions of the human alpha-skeletal actin gene synergistically modulate muscle-specific expression. Mol Cell Biol (1987) 2.00
Rat gene encoding the 78-kDa glucose-regulated protein GRP78: its regulatory sequences and the effect of protein glycosylation on its expression. Proc Natl Acad Sci U S A (1987) 1.87
Characterization of Gmhsp26-A, a stress gene encoding a divergent heat shock protein of soybean: heavy-metal-induced inhibition of intron processing. Mol Cell Biol (1988) 1.84
Characterization of a novel chicken heat shock transcription factor, heat shock factor 3, suggests a new regulatory pathway. Mol Cell Biol (1993) 1.81
Interferons increase transcription of a major histocompatibility class I gene via a 5' interferon consensus sequence. Mol Cell Biol (1987) 1.78
Multiple basal elements of a human hsp70 promoter function differently in human and rodent cell lines. Mol Cell Biol (1987) 1.77
Cloning and expression of a gene encoding hsc73, the major hsp70-like protein in unstressed rat cells. EMBO J (1987) 1.67
Heat shock and the sorting of luminal ER proteins. EMBO J (1989) 1.54
Maximal stress-induced transcription from the human HSP70 promoter requires interactions with the basal promoter elements independent of rotational alignment. Mol Cell Biol (1990) 1.48
Cell-cycle-specific interaction of nuclear DNA-binding proteins with a CCAAT sequence from the human thymidine kinase gene. Proc Natl Acad Sci U S A (1987) 1.45
The ocs element: a 16 base pair palindrome essential for activity of the octopine synthase enhancer. EMBO J (1987) 1.45
A characterization of the elements comprising the promoter of the mouse ribosomal protein gene RPS16. Nucleic Acids Res (1989) 1.39
Multiple regulatory regions on the 5' side of the mouse E alpha gene. Proc Natl Acad Sci U S A (1988) 1.38
In vivo footprinting of a low molecular weight glutenin gene (LMWG-1D1) in wheat endosperm. EMBO J (1993) 1.28
An element downstream of the cap site is required for transcription of the gene encoding mouse ribosomal protein L32. Proc Natl Acad Sci U S A (1989) 1.27
Several different upstream promoter elements can potentiate transactivation by the BPV-1 E2 protein. EMBO J (1991) 1.25
Vsx2 in the zebrafish retina: restricted lineages through derepression. Neural Dev (2009) 1.23
B-cell-specific enhancer activity of conserved upstream elements of the class II major histocompatibility complex DQB gene. Proc Natl Acad Sci U S A (1988) 1.23
The role of ACE3 in Drosophila chorion gene amplification. EMBO J (1989) 1.23
The immunoglobulin heavy-chain enhancer functions as the promoter for I mu sterile transcription. Mol Cell Biol (1990) 1.21
Determination of heat-shock transcription factor 2 stoichiometry at looped DNA complexes using scanning force microscopy. EMBO J (1995) 1.19
Organization of the Drosophila melanogaster hsp70 heat shock regulation unit. Mol Cell Biol (1987) 1.19
A cis-acting element and associated binding factor required for CNS expression of the Drosophila melanogaster dopa decarboxylase gene. EMBO J (1988) 1.18
Identification of a novel TA-rich DNA binding protein that recognizes a TATA sequence within the brain creatine kinase promoter. Nucleic Acids Res (1988) 1.18
Role of chromatin and Xenopus laevis heat shock transcription factor in regulation of transcription from the X. laevis hsp70 promoter in vivo. Mol Cell Biol (1995) 1.16
Architectural and Functional Commonalities between Enhancers and Promoters. Cell (2015) 1.14
TATA-dependent and TATA-independent function of the basal and heat shock elements of a human hsp70 promoter. Mol Cell Biol (1990) 1.09
Coordinate action of a proximal homeoprotein binding site and a distal sequence confers the Ultrabithorax expression pattern in the visceral mesoderm. EMBO J (1989) 1.05
Dual function of a nuclear factor I binding site in MMTV transcription regulation. Nucleic Acids Res (1989) 1.04
Sex-specific control of Drosophila melanogaster yolk protein 1 gene expression is limited to transcription. Mol Cell Biol (1988) 1.01
Unusual DNA binding characteristics of an in vitro translation product of the CCAAT binding protein mYB-1. Nucleic Acids Res (1992) 1.00
Regulatory domains of the Gmhsp17.5-E heat shock promoter of soybean. Mol Cell Biol (1989) 1.00
Interaction between two different regulatory elements activates the murine alpha A-crystallin gene promoter in explanted lens epithelia. Mol Cell Biol (1987) 0.99
trans-activation of the simian virus 40 enhancer by a pX product of human T-cell leukemia virus type I. J Virol (1988) 0.98
Artificial combination of two cis-regulatory elements generates a unique pattern of expression in transgenic plants. Proc Natl Acad Sci U S A (1987) 0.94
Identification of cis-acting regulatory elements in the promoter region of the rat brain creatine kinase gene. Mol Cell Biol (1990) 0.94
Modular recognition of 5-base-pair DNA sequence motifs by human heat shock transcription factor. Mol Cell Biol (1991) 0.94
Mammalian Heat Shock Response and Mechanisms Underlying Its Genome-wide Transcriptional Regulation. Mol Cell (2016) 0.94
In situ detection of a heat-shock regulatory element binding protein using a soluble synthetic enhancer sequence. Nucleic Acids Res (1989) 0.92
DNA-binding protein activated by gamma radiation in human cells. Mol Cell Biol (1990) 0.92
Upstream regulatory region for inducible expression of the chicken skeletal myosin alkali light-chain gene. Mol Cell Biol (1988) 0.90
Genomic organization of the Neurospora crassa gsn gene: possible involvement of the STRE and HSE elements in the modulation of transcription during heat shock. Mol Genet Genomics (2004) 0.89
Canonical modeling of the multi-scale regulation of the heat stress response in yeast. Metabolites (2012) 0.88
Simian virus 40 revertant enhancers exhibit restricted host ranges for enhancer function. J Virol (1988) 0.87
Small molecule activators of the heat shock response: chemical properties, molecular targets, and therapeutic promise. Chem Res Toxicol (2012) 0.86
Development of useful recombinant promoter and its expression analysis in different plant cells using confocal laser scanning microscopy. PLoS One (2011) 0.86
A specific domain of the adenovirus EIV promoter is necessary to maintain susceptibility of the integrated promoter to EIA transactivation. Mol Cell Biol (1988) 0.85
In Vitro Interaction of Nuclear Proteins with the Promoter of Soybean Heat Shock Gene Gmhsp17.5E. Plant Physiol (1990) 0.82
High-throughput functional comparison of promoter and enhancer activities. Genome Res (2016) 0.80
Transcription factors GAF and HSF act at distinct regulatory steps to modulate stress-induced gene activation. Genes Dev (2016) 0.80
A novel estrogen receptor intramolecular folding-based titratable transgene expression system. Mol Ther (2009) 0.79
Xenopus transcription factors: key molecules in the developmental regulation of differential gene expression. Biochem J (1991) 0.78
Identification of a protein that interacts with the nuclear factor-1 (NF-1) binding site in cells that do not express NF-1: comparison to NF-1, cellular distribution, and effect on transcription. Nucleic Acids Res (1991) 0.78
Heat shock stimulation of a tilapia heat shock protein 70 promoter is mediated by a distal element. Biochem J (2001) 0.77
Isolation of mutations that act in trans to alter expression from a yeast hsp70 promoter. Mol Cell Biol (1988) 0.76
Isolation and functional analysis of chicken 90-kDa heat shock protein gene promoter. Nucleic Acids Res (1989) 0.76
Effect of Low Doses (5-40 cGy) of Gamma-irradiation on Lifespan and Stress-related Genes Expression Profile in Drosophila melanogaster. PLoS One (2015) 0.76
An efficient mRNA-dependent translation system from reticulocyte lysates. Eur J Biochem (1976) 46.42
A C-terminal signal prevents secretion of luminal ER proteins. Cell (1987) 14.83
A regulatory upstream promoter element in the Drosophila hsp 70 heat-shock gene. Cell (1982) 14.32
An Hsp70-like protein in the ER: identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein. Cell (1986) 10.38
Speculations on the functions of the major heat shock and glucose-regulated proteins. Cell (1986) 10.35
Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation. Cell (1988) 7.06
A specific transcription factor that can bind either the 5S RNA gene or 5S RNA. Proc Natl Acad Sci U S A (1980) 5.80
Heat shock factor is regulated differently in yeast and HeLa cells. Nature (1987) 5.40
A synthetic heat-shock promoter element confers heat-inducibility on the herpes simplex virus thymidine kinase gene. EMBO J (1982) 5.19
Homotypic vacuolar fusion mediated by t- and v-SNAREs. Nature (1997) 4.99
A male accessory gland peptide that regulates reproductive behavior of female D. melanogaster. Cell (1988) 4.67
ERD2, a yeast gene required for the receptor-mediated retrieval of luminal ER proteins from the secretory pathway. Cell (1990) 4.54
Purification and characterization of a heat-shock element binding protein from yeast. EMBO J (1987) 4.43
Translation of encephalomyocarditis virus RNA in vitro yields an active proteolytic processing enzyme. Eur J Biochem (1978) 4.16
Ligand-induced redistribution of a human KDEL receptor from the Golgi complex to the endoplasmic reticulum. Cell (1992) 3.82
SED5 encodes a 39-kD integral membrane protein required for vesicular transport between the ER and the Golgi complex. J Cell Biol (1992) 3.79
LEF-1, a nuclear factor coordinating signaling inputs from wingless and decapentaplegic. Cell (1997) 3.63
Two syntaxin homologues in the TGN/endosomal system of yeast. EMBO J (1998) 3.48
dMi-2, a hunchback-interacting protein that functions in polycomb repression. Science (1998) 3.48
Leaky UAG termination codon in tobacco mosaic virus RNA. Nature (1978) 3.45
A vacuolar v-t-SNARE complex, the predominant form in vivo and on isolated vacuoles, is disassembled and activated for docking and fusion. J Cell Biol (1998) 3.44
Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx. Cell (1995) 3.41
Specific retrieval of the exocytic SNARE Snc1p from early yeast endosomes. Mol Biol Cell (2000) 3.32
Hsp70 accelerates the recovery of nucleolar morphology after heat shock. EMBO J (1984) 3.24
Sorting of proteins into multivesicular bodies: ubiquitin-dependent and -independent targeting. EMBO J (2001) 3.05
Constitutive binding of yeast heat shock factor to DNA in vivo. Mol Cell Biol (1988) 2.98
Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling. Nature (1998) 2.98
A human homologue of the yeast HDEL receptor. Nature (1990) 2.91
The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation. EMBO J (2001) 2.87
The APC tumour suppressor has a nuclear export function. Nature (2000) 2.82
Use of peptide tagging to detect proteins expressed from cloned genes: deletion mapping functional domains of Drosophila hsp 70. EMBO J (1984) 2.78
The use of promoter fusions in Drosophila genetics: isolation of mutations affecting the heat shock response. Cell (1984) 2.71
Involvement of ATP in the nuclear and nucleolar functions of the 70 kd heat shock protein. EMBO J (1985) 2.64
Mechanisms of heat-shock gene activation in higher eukaryotes. Adv Genet (1987) 2.58
Association of an S1 nuclease-sensitive structure with short direct repeats 5' of Drosophila heat shock genes. Nature (1983) 2.53
ERD1, a yeast gene required for the retention of luminal endoplasmic reticulum proteins, affects glycoprotein processing in the Golgi apparatus. EMBO J (1990) 2.53
The ERD2 gene determines the specificity of the luminal ER protein retention system. Cell (1990) 2.47
SNARE-mediated retrograde traffic from the Golgi complex to the endoplasmic reticulum. Cell (1996) 2.44
The heat-shock response in Xenopus oocytes is controlled at the translational level. Cell (1982) 2.40
Xenopus hsp 70 genes are constitutively expressed in injected oocytes. EMBO J (1984) 2.38
Recycling of proteins from the Golgi compartment to the ER in yeast. J Cell Biol (1990) 2.38
Localization of Sed5, a putative vesicle targeting molecule, to the cis-Golgi network involves both its transmembrane and cytoplasmic domains. J Cell Biol (1994) 2.32
The dynamics of golgi protein traffic visualized in living yeast cells. Mol Biol Cell (1998) 2.29
Transmembrane domain-dependent sorting of proteins to the ER and plasma membrane in yeast. EMBO J (1997) 2.28
A SNARE-like protein required for traffic through the Golgi complex. Nature (1995) 2.15
Seventy-kilodalton heat shock proteins and an additional component from reticulocyte lysate stimulate import of M13 procoat protein into microsomes. EMBO J (1988) 2.09
Ric1p and Rgp1p form a complex that catalyses nucleotide exchange on Ypt6p. EMBO J (2000) 2.04
Silencers in abdominal-B, a homeotic Drosophila gene. EMBO J (1993) 2.03
Induction across germ layers in Drosophila mediated by a genetic cascade. Cell (1990) 2.00
Long range repression conferring boundaries of Ultrabithorax expression in the Drosophila embryo. EMBO J (1991) 1.97
Developmental control of the heat shock response in Xenopus. Proc Natl Acad Sci U S A (1984) 1.95
pH-dependent binding of KDEL to its receptor in vitro. J Biol Chem (1993) 1.91
Synthesis and proteolytic processing of cowpea mosaic virus proteins in reticulocyte lysates. Virology (1979) 1.91
A novel SNARE complex implicated in vesicle fusion with the endoplasmic reticulum. EMBO J (1997) 1.88
Activation of the Drosophila hsp27 promoter by heat shock and by ecdysone involves independent and remote regulatory sequences. EMBO J (1986) 1.87
A selective transport route from Golgi to late endosomes that requires the yeast GGA proteins. J Cell Biol (2000) 1.85
SNAREs and membrane fusion in the Golgi apparatus. Biochim Biophys Acta (1998) 1.80
A conserved heptapeptide restrains the activity of the yeast heat shock transcription factor. EMBO J (1991) 1.77
The syntaxin Tlg1p mediates trafficking of chitin synthase III to polarized growth sites in yeast. Mol Biol Cell (1998) 1.77
Drosophila homoeotic genes encode transcriptional activators similar to mammalian OTF-2. Nature (1988) 1.76
Genes that allow yeast cells to grow in the absence of the HDEL receptor. EMBO J (1992) 1.73
Expression of a Drosophila heat-shock protein in Xenopus oocytes: conserved and divergent regulatory signals. EMBO J (1982) 1.72
The Saccharomyces cerevisiae SEC20 gene encodes a membrane glycoprotein which is sorted by the HDEL retrieval system. EMBO J (1992) 1.69
Immunological evidence that plants use both HDEL and KDEL for targeting proteins to the endoplasmic reticulum. J Cell Sci (1992) 1.69
The Sec1p homologue Vps45p binds to the syntaxin Tlg2p. Eur J Cell Biol (1998) 1.69
Cloning and expression of a gene encoding hsc73, the major hsp70-like protein in unstressed rat cells. EMBO J (1987) 1.67
A new Drosophila APC homologue associated with adhesive zones of epithelial cells. Nat Cell Biol (1999) 1.66
An effector of Ypt6p binds the SNARE Tlg1p and mediates selective fusion of vesicles with late Golgi membranes. EMBO J (2001) 1.62
Mutational analysis of the human KDEL receptor: distinct structural requirements for Golgi retention, ligand binding and retrograde transport. EMBO J (1993) 1.60
Polar transmembrane domains target proteins to the interior of the yeast vacuole. Mol Biol Cell (2000) 1.56
Segmental determination in Drosophila conferred by hunchback (hb), a repressor of the homeotic gene Ultrabithorax (Ubx). Proc Natl Acad Sci U S A (1992) 1.54
Actin-dependent membrane association of the APC tumour suppressor in polarized mammalian epithelial cells. EMBO J (2001) 1.53
A CREB-binding site as a target for decapentaplegic signalling during Drosophila endoderm induction. EMBO J (1997) 1.52
Translation of fragmented viral RNA in vitro: initiation at multiple sites. FEBS Lett (1979) 1.46
The KKXX signal mediates retrieval of membrane proteins from the Golgi to the ER in yeast. Eur J Cell Biol (1994) 1.46
Spindles cotton on to junctions, APC and EB1. Nat Cell Biol (2001) 1.46
Evidence that the Abdominal-B r element function is conferred by a trans-regulatory homeoprotein. EMBO J (1988) 1.43
The glucose-regulated protein grp94 is related to heat shock protein hsp90. J Mol Biol (1987) 1.42
An ecdysone response element in the Drosophila hsp27 promoter. EMBO J (1987) 1.39
Homeotic gene expression in the visceral mesoderm of Drosophila embryos. EMBO J (1989) 1.37
Related 5S RNA transcription factors in Xenopus oocytes and somatic cells. Proc Natl Acad Sci U S A (1981) 1.34
Antagonism between EGFR and Wingless signalling in the larval cuticle of Drosophila. Development (1997) 1.32
EGF receptor/Rolled MAP kinase signalling protects cells against activated Armadillo in the Drosophila eye. EMBO Rep (2001) 1.32
Got1p and Sft2p: membrane proteins involved in traffic to the Golgi complex. EMBO J (1999) 1.30
The structure of the Ultrabithorax promoter of Drosophila melanogaster. EMBO J (1987) 1.28
A CCAAT box confers cell-type-specific regulation on the Xenopus hsp70 gene in oocytes. Cell (1986) 1.28
Sharp anterior boundary of homeotic gene expression conferred by the fushi tarazu protein. EMBO J (1992) 1.26
Mutations affecting the indirect flight muscles of Drosophila melanogaster. J Embryol Exp Morphol (1982) 1.24
The TIP1 gene of Saccharomyces cerevisiae encodes an 80 kDa cytoplasmic protein that interacts with the cytoplasmic domain of Sec20p. EMBO J (1993) 1.24
Characteristics of a coupled cell-free transcription and translation system directed by vaccinia cores. Eur J Biochem (1978) 1.23
Transcription of Drosophila small hsp-tk hybrid genes is induced by heat shock and by ecdysterone in transfected Drosophila cells. Proc Natl Acad Sci U S A (1985) 1.21
A human tRNAGlu gene of high transcriptional activity. Nucleic Acids Res (1983) 1.21
Expression of Abdominal-B homeoproteins in Drosophila embryos. Development (1990) 1.21
Functional dissection of Drosophila abdominal-B protein. Mech Dev (1991) 1.20
Specification of a single cell type by a Drosophila homeotic gene. Cell (1994) 1.20
Induction of labial expression in the Drosophila endoderm: response elements for dpp signalling and for autoregulation. Development (1992) 1.17
Functional intertwining of Dpp and EGFR signaling during Drosophila endoderm induction. Genes Dev (1998) 1.14
Actin-dependent membrane association of a Drosophila epithelial APC protein and its effect on junctional Armadillo. Curr Biol (2000) 1.14