W T Garrard

Author PubWeight™ 100.25‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Nuclease hypersensitive sites in chromatin. Annu Rev Biochem 1988 13.48
2 Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites. Cell 1986 6.16
3 The ubiquitous potential Z-forming sequence of eucaryotes, (dT-dG)n . (dC-dA)n, is not detectable in the genomes of eubacteria, archaebacteria, or mitochondria. Mol Cell Biol 1986 3.00
4 Chromatin structure of the potential Z-forming sequence (dT-dG)n X (dC-dA)n. Evidence for an "alternating-B" conformation. J Mol Biol 1985 2.58
5 The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis. Proc Natl Acad Sci U S A 1998 2.38
6 Partial purification of the template-active fraction of chromatin: a preliminary report. Proc Natl Acad Sci U S A 1974 2.25
7 The enhancer of the immunoglobulin heavy chain locus is flanked by presumptive chromosomal loop anchorage elements. J Biol Chem 1987 2.15
8 Differentiation-dependent chromatin alterations precede and accompany transcription of immunoglobulin light chain genes. J Biol Chem 1984 1.99
9 Transcription-induced nucleosome 'splitting': an underlying structure for DNase I sensitive chromatin. EMBO J 1991 1.93
10 Dysfunction of chromosomal loop attachment sites: illegitimate recombination linked to matrix association regions and topoisomerase II. Proc Natl Acad Sci U S A 1989 1.91
11 Points of contact between histone H1 and the histone octamer. Proc Natl Acad Sci U S A 1980 1.74
12 Subunit structures of different electrophoretic forms of nucleosomes. J Biol Chem 1980 1.61
13 Action of recombinant human apoptotic endonuclease G on naked DNA and chromatin substrates: cooperation with exonuclease and DNase I. J Biol Chem 2001 1.53
14 Two-dimensional electrophoretic analysis of polynucleosomes. J Biol Chem 1977 1.50
15 Sharp boundaries demarcate the chromatin structure of a yeast heat-shock gene. J Mol Biol 1987 1.47
16 Reassociation of histone H1 with nucleosomes. J Biol Chem 1979 1.44
17 Nitrate reductase and soluble cytochrome c in Spirillum itersonii. J Bacteriol 1970 1.38
18 Chromosomal loop anchorage sites appear to be evolutionarily conserved. FEBS Lett 1986 1.38
19 Basal-level expression of the yeast HSP82 gene requires a heat shock regulatory element. Mol Cell Biol 1989 1.33
20 5-methylcytosine is localized in nucleosomes that contain histone H1. Proc Natl Acad Sci U S A 1983 1.32
21 Cleavage preferences of the apoptotic endonuclease DFF40 (caspase-activated DNase or nuclease) on naked DNA and chromatin substrates. J Biol Chem 2000 1.32
22 Transcription termination and chromatin structure of the active immunoglobulin kappa gene locus. J Biol Chem 1986 1.27
23 Positive DNA supercoiling generates a chromatin conformation characteristic of highly active genes. Proc Natl Acad Sci U S A 1991 1.24
24 Varigated chromatin structures of mouse ribosomal RNA genes. J Mol Biol 1983 1.24
25 Functional organization of the mammalian genome. Cold Spring Harb Symp Quant Biol 1974 1.20
26 DNA supercoiling in chromatin structure and gene expression. Crit Rev Eukaryot Gene Expr 1992 1.19
27 Immunoglobulin kappa gene expression after stable integration. I. Role of the intronic MAR and enhancer in plasmacytoma cells. J Biol Chem 1989 1.18
28 Immunoglobulin kappa gene expression after stable integration. II. Role of the intronic MAR and enhancer in transgenic mice. J Biol Chem 1989 1.16
29 Uncoupling gene activity from chromatin structure: promoter mutations can inactivate transcription of the yeast HSP82 gene without eliminating nucleosome-free regions. Proc Natl Acad Sci U S A 1992 1.13
30 Histone molar ratios among different electrophoretic forms of mono- and dinucleosomes. J Biol Chem 1979 1.13
31 Electrophoretic analyses of nucleosomes and other protein-DNA complexes. Methods Enzymol 1989 1.11
32 Synthesis, assembly, and localization of periplasmic cytochrome c. J Biol Chem 1972 1.09
33 Selective release of proteins from Spirillum itersonii by tris (hydroxymethyl) aminomethane and ethylenediaminetetraacetate. J Bacteriol 1971 1.08
34 Overall pathway of mononucleosome production. J Biol Chem 1979 1.08
35 Purification and properties of a neutral protease from rat liver chromatin. Biochemistry 1974 1.07
36 Identification within the simian virus 40 genome of a chromosomal loop attachment site that contains topoisomerase II cleavage sites. J Virol 1990 1.07
37 Stoichiometry of chromatin proteins. Biochem Biophys Res Commun 1974 1.06
38 Vacuum blotting: a simple method for transferring DNA from sequencing gels to nylon membranes. Gene 1988 1.06
39 Protein:DNA interactions at chromosomal loop attachment sites. Genome 1989 1.04
40 Regulation of the human apoptotic DNase/RNase endonuclease G: involvement of Hsp70 and ATP. Apoptosis 2005 1.04
41 Nonheme iron proteins. IV. Structural studies of Micrococcus aerogenes rubredoxin. Biochemistry 1968 1.02
42 Amino acid sequence of the N-terminal domain of calf thymus histone H2A.Z. FEBS Lett 1983 1.02
43 The active immunoglobulin kappa chain gene is packaged by non-ubiquitin-conjugated nucleosomes. Proc Natl Acad Sci U S A 1986 1.01
44 Roles of the major apoptotic nuclease-DNA fragmentation factor-in biology and disease. Cell Mol Life Sci 2009 0.97
45 RNA polymerase-specific nucleosome disruption by transcription in vivo. J Biol Chem 1999 0.95
46 Ionic and cofactor requirements for the activity of the apoptotic endonuclease DFF40/CAD. Mol Cell Biochem 2001 0.93
47 Changes in chromatin proteins during liver regeneration. J Biol Chem 1974 0.93
48 Yeast calmodulin and a conserved nuclear protein participate in the in vivo binding of a matrix association region. Proc Natl Acad Sci U S A 1993 0.93
49 MARs of antigen receptor and co-receptor genes. Crit Rev Eukaryot Gene Expr 1999 0.91
50 Immunoglobulin kappa gene enhancers synergistically activate gene expression but independently determine chromatin structure. J Biol Chem 1992 0.91
51 Heterogeneity in nucleosome spacing. J Biol Chem 1977 0.90
52 Evidence that the Igkappa gene MAR regulates the probability of premature V-J joining and somatic hypermutation. J Immunol 1999 0.90
53 In vitro chromatin assembly of the HIV-1 promoter. ATP-dependent polar repositioning of nucleosomes by Sp1 and NFkappaB. J Biol Chem 1997 0.89
54 Template topology and transcription: chromatin templates relaxed by localized linearization are transcriptionally active in yeast. Mol Cell Biol 1997 0.87
55 A targeted kappa immunoglobulin gene containing a deletion of the nuclear matrix association region exhibits spontaneous hyper-recombination in pre-B cells. Mol Immunol 1998 0.86
56 High-level rearrangement and transcription of yeast artificial chromosome-based mouse Ig kappa transgenes containing distal regions of the contig. J Immunol 2000 0.85
57 Two forms of rat liver histone H3. FEBS Lett 1976 0.85
58 Transferring DNA from electrophoretically resolved nucleosomes to diazobenzyloxymethyl cellulose: properties of nucleosomes along mouse satellite DNA. Nucleic Acids Res 1982 0.84
59 A method for mapping the distributions of modified and variant histones among mono- and polynucleosomes. J Biol Chem 1978 0.83
60 A nonamer of histones in chromatin. J Biol Chem 1980 0.82
61 Nucleosome arrangement with regard to DNA base composition. J Biol Chem 1979 0.82
62 Biology of the histones. Life Sci 1974 0.81
63 Preparation of chromatin from animal tissues and cultured cells. Methods Cell Biol 1978 0.80
64 Temperature-dependent cleavage of chromatin by micrococcal nuclease near the nucleosome center. FEBS Lett 1986 0.80
65 A method for genome comparisons and hybridization studies using known megabase-scale DNA sequences as a reference. Genomics 1997 0.80
66 Histone H3 disulfide reactions in interphase, mitotic, and native chromatin. J Biol Chem 1977 0.78
67 Yeast artificial chromosome contigs reveal that distal variable-region genes reside at least 3 megabases from the joining regions in the murine immunoglobulin kappa locus. Proc Natl Acad Sci U S A 1995 0.78
68 Mutations that affect nuclear organization in yeast. Methods Cell Biol 1991 0.78
69 Nucleotide sequence of the intron of the germline human kappa immunoglobulin gene connecting the J and C regions reveals a matrix association region (MAR) next to the enhancer. Nucleic Acids Res 1992 0.78
70 Nucleosomes and regulation of gene expression. Structure of the HIV-1 5'LTR. Acta Biochim Pol 1998 0.76
71 Targeted linearization of DNA in vivo. Methods 1999 0.75
72 Histone phosphorylation during liver regeneration. Biochem Biophys Res Commun 1976 0.75
73 Accurate quantification of expression of transgenes marked with restriction endonuclease site polymorphisms by RT-PCR. Biotechniques 1998 0.75