Published in Proc Natl Acad Sci U S A on December 01, 1988
The impact of O2 availability on human cancer. Nat Rev Cancer (2008) 6.84
A microhomology-mediated break-induced replication model for the origin of human copy number variation. PLoS Genet (2009) 6.39
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5. J Clin Invest (2009) 3.01
The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis. J Clin Pathol (2004) 2.74
Evolutionary dynamics of carcinogenesis and why targeted therapy does not work. Nat Rev Cancer (2012) 2.71
Three-dimensional context regulation of metastasis. Clin Exp Metastasis (2008) 2.49
Decreased expression of the DNA mismatch repair gene Mlh1 under hypoxic stress in mammalian cells. Mol Cell Biol (2003) 2.12
Down-regulation of Rad51 and decreased homologous recombination in hypoxic cancer cells. Mol Cell Biol (2004) 2.09
Nonlinear modelling of cancer: bridging the gap between cells and tumours. Nonlinearity (2010) 2.08
The tumor microenvironment and metastatic disease. Clin Exp Metastasis (2008) 1.91
Correlation of high lactate levels in head and neck tumors with incidence of metastasis. Am J Pathol (1997) 1.86
What is the malignant nature of human ductal carcinoma in situ? Nat Rev Cancer (2010) 1.86
Adaptation to hypoxia and acidosis in carcinogenesis and tumor progression. Semin Cancer Biol (2008) 1.76
[(18)F]FMISO and [(18)F]FDG PET imaging in soft tissue sarcomas: correlation of hypoxia, metabolism and VEGF expression. Eur J Nucl Med Mol Imaging (2003) 1.62
Cellular and molecular mechanisms underlying oxygen-dependent radiosensitivity. Radiat Res (2015) 1.53
Glucose starvation and acidosis: effect on experimental metastatic potential, DNA content and MTX resistance of murine tumour cells. Br J Cancer (1991) 1.52
Maspin regulates hypoxia-mediated stimulation of uPA/uPAR complex in invasive breast cancer cells. Cancer Biol Ther (2005) 1.49
Hypoxia-induced treatment failure in advanced squamous cell carcinoma of the uterine cervix is primarily due to hypoxia-induced radiation resistance rather than hypoxia-induced metastasis. Br J Cancer (2000) 1.39
Three-dimensional multispecies nonlinear tumor growth-II: Tumor invasion and angiogenesis. J Theor Biol (2010) 1.37
Exposure to hypoxia, glucose starvation and acidosis: effect on invasive capacity of murine tumor cells and correlation with cathepsin (L + B) secretion. Clin Exp Metastasis (1997) 1.37
Tumour hypoxia and vascular density as predictors of metastasis in squamous cell carcinoma of the uterine cervix. Br J Cancer (1998) 1.35
Inactivation of the CYLD deubiquitinase by HPV E6 mediates hypoxia-induced NF-kappaB activation. Cancer Cell (2008) 1.27
Hypoxia in models of lung cancer: implications for targeted therapeutics. Clin Cancer Res (2010) 1.19
Hypoxic tumor microenvironment and cancer cell differentiation. Curr Mol Med (2009) 1.19
Hypoxia-induced metastasis of human melanoma cells: involvement of vascular endothelial growth factor-mediated angiogenesis. Br J Cancer (1999) 1.18
Anoxia-induced up-regulation of interleukin-8 in human malignant melanoma. A potential mechanism for high tumor aggressiveness. Am J Pathol (1999) 1.16
Relationship of hypoxia to metastatic ability in rodent tumours. Br J Cancer (2001) 1.15
Tumor oxygen dynamics: correlation of in vivo MRI with histological findings. Neoplasia (2003) 1.15
Hypoxia-induced epigenetic regulation and silencing of the BRCA1 promoter. Mol Cell Biol (2011) 1.13
Regulation of E-cadherin: does hypoxia initiate the metastatic cascade? Mol Pathol (1999) 1.11
Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxia. J Cell Biol (2013) 1.10
Interstitial fluid pressure, vascularity and metastasis in ectopic, orthotopic and spontaneous tumours. BMC Cancer (2008) 1.07
Regulation of cancer metastasis by stress pathways. Clin Exp Metastasis (2003) 1.07
Impact of the hypoxic tumor microenvironment on the regulation of cancer stem cell characteristics. Cancer Biol Ther (2010) 1.06
Imaging prostate cancer invasion with multi-nuclear magnetic resonance methods: the Metabolic Boyden Chamber. Neoplasia (2000) 1.01
Near infrared luminescent oxygen nanosensors with nanoparticle matrix tailored sensitivity. Anal Chem (2010) 0.99
Hypoxia-associated spontaneous pulmonary metastasis in human melanoma xenografts: involvement of microvascular hot spots induced in hypoxic foci by interleukin 8. Br J Cancer (2002) 0.99
Defining normoxia, physoxia and hypoxia in tumours-implications for treatment response. Br J Radiol (2014) 0.99
Regulation of c-jun expression during hypoxic and low-glucose stress. Mol Cell Biol (1994) 0.96
Lifetime-based photoacoustic oxygen sensing in vivo. J Biomed Opt (2012) 0.95
Prolyl hydroxylase PHD3 enhances the hypoxic survival and G1 to S transition of carcinoma cells. PLoS One (2011) 0.94
Multifaceted control of DNA repair pathways by the hypoxic tumor microenvironment. DNA Repair (Amst) (2015) 0.93
Ozone Therapy for Tumor Oxygenation: a Pilot Study. Evid Based Complement Alternat Med (2004) 0.93
Tumor hypoxia and genetic alterations in sporadic cancers. J Obstet Gynaecol Res (2011) 0.93
Tumor hypoxia as a driving force in genetic instability. Genome Integr (2013) 0.92
Hypoxia modulates A431 cellular pathways association to tumor radioresistance and enhanced migration revealed by comprehensive proteomic and functional studies. Mol Cell Proteomics (2012) 0.92
Changes in growth characteristics and macromolecular synthesis on recovery from severe hypoxia. Br J Cancer (1990) 0.91
Radiation sensitivity of tumour cells stained in vitro or in vivo with the bisbenzimide fluorochrome Hoechst 33342. Br J Cancer (1989) 0.91
The tumor microenvironment and DNA repair. Semin Radiat Oncol (2010) 0.91
Controlled DNA "damage" and repair in hypoxic signaling. Respir Physiol Neurobiol (2010) 0.88
A quantitative analysis of the reduction in oxygen levels required to induce up-regulation of vascular endothelial growth factor (VEGF) mRNA in cervical cancer cell lines. Br J Cancer (1999) 0.88
Silencing of the DNA mismatch repair gene MLH1 induced by hypoxic stress in a pathway dependent on the histone demethylase LSD1. Cell Rep (2014) 0.88
Hypoxia facilitates tumour cell detachment by reducing expression of surface adhesion molecules and adhesion to extracellular matrices without loss of cell viability. Br J Cancer (1998) 0.87
Cancer stem cell theory and the warburg effect, two sides of the same coin? Int J Mol Sci (2014) 0.87
Hypoxia and DNA repair. Yale J Biol Med (2013) 0.86
Molecular Imaging of Hypoxia: Strategies for Probe Design and Application. Curr Org Synth (2011) 0.86
Hypoxia-induced angiogenesis and vascular endothelial growth factor secretion in human melanoma. Br J Cancer (1998) 0.86
Environmental stress induces trinucleotide repeat mutagenesis in human cells. Proc Natl Acad Sci U S A (2015) 0.86
Imaging tumor hypoxia to advance radiation oncology. Antioxid Redox Signal (2014) 0.83
Increased expression of a nucleolar Nop5/Sik family member in metastatic melanoma cells: evidence for its role in nucleolar sizing and function. Am J Pathol (2001) 0.83
Quantitative profiling of chromatome dynamics reveals a novel role for HP1BP3 in hypoxia-induced oncogenesis. Mol Cell Proteomics (2014) 0.82
Intermittent hypoxia selects for genotypes and phenotypes that increase survival, invasion, and therapy resistance. PLoS One (2015) 0.82
Cell cycle progression in response to oxygen levels. Cell Mol Life Sci (2014) 0.82
Analysis of the effects of exposure to acute hypoxia on oxidative lesions and tumour progression in a transgenic mouse breast cancer model. BMC Cancer (2008) 0.81
Hypoxia-induced tetraploidisation of a diploid human melanoma cell line in vitro. Br J Cancer Suppl (1996) 0.81
Down-regulation of NDRG1 promotes migration of cancer cells during reoxygenation. PLoS One (2011) 0.81
Hypoxia and regulation of cancer cell stemness. Adv Exp Med Biol (2014) 0.81
Intermittent induction of HIF-1α produces lasting effects on malignant progression independent of its continued expression. PLoS One (2015) 0.80
Transient perfusion in human melanoma xenografts. Br J Cancer (1995) 0.80
Inhibition of the HIF1α-p300 interaction by quinone- and indandione-mediated ejection of structural Zn(II). Eur J Med Chem (2014) 0.80
Cisplatin and CCNU synergism in spheroid cell subpopulations. Br J Cancer (1990) 0.80
HIF-1α Promotes A Hypoxia-Independent Cell Migration. Open Biol J (2010) 0.79
Graded hypoxia modulates the invasive potential of HT1080 fibrosarcoma and MDA MB231 carcinoma cells. Clin Exp Metastasis (2008) 0.79
Hypoxic stress facilitates acute activation and chronic downregulation of fanconi anemia proteins. Mol Cancer Res (2014) 0.79
Energy metabolism in human melanoma cells under hypoxic and acidic conditions in vitro. Br J Cancer (1997) 0.78
Attacking breast cancer at the preinvasion stage by targeting autophagy. Womens Health (Lond Engl) (2013) 0.78
Antimetastatic activity of MONCPT in preclinical melanoma mice model. Invest New Drugs (2009) 0.76
Molecular and functional imaging of invasion and metastasis: windows into the metastatic cascade. Cancer Biomark (2010) 0.76
Effects of radiation on metastasis and tumor cell migration. Cell Mol Life Sci (2016) 0.75
Pathophysiological Basis for the Formation of the Tumor Microenvironment. Front Oncol (2016) 0.75
Blood flow responses to mild-intensity exercise in ectopic vs. orthotopic prostate tumors; dependence upon host tissue hemodynamics and vascular reactivity. J Appl Physiol (1985) (2016) 0.75
Hypoxia-activated cytotoxicity of benznidazole against clonogenic tumor cells. Cancer Biol Ther (2016) 0.75
Down-regulation of DNA mismatch repair enhances initiation and growth of neuroblastoma and brain tumour multicellular spheroids. PLoS One (2011) 0.75
Oxygen supply maps for hypoxic microenvironment visualization in prostate cancer. J Pathol Inform (2016) 0.75
Promotion of a cancer-like phenotype, through chronic exposure to inflammatory cytokines and hypoxia in a bronchial epithelial cell line model. Sci Rep (2016) 0.75
Patterns of Vasculature in Mouse Models of Lung Cancer Are Dependent on Location. Mol Imaging Biol (2016) 0.75
Metastasis: quantitative analysis of distribution and fate of tumor emboli labeled with 125 I-5-iodo-2'-deoxyuridine. J Natl Cancer Inst (1970) 4.88
A rapid single step staining technique for DNA analysis by flow microfluorimetry. J Histochem Cytochem (1980) 2.76
Gene amplification in a single cell cycle in Chinese hamster ovary cells. J Biol Chem (1984) 2.32
On the possibility of metabolic control of replicon "misfiring": relationship to emergence of malignant phenotypes in mammalian cell lineages. Proc Natl Acad Sci U S A (1981) 1.61
Transient hypoxia enhances the frequency of dihydrofolate reductase gene amplification in Chinese hamster ovary cells. Proc Natl Acad Sci U S A (1986) 1.61
UV radiation facilitates methotrexate resistance and amplification of the dihydrofolate reductase gene in cultured 3T6 mouse cells. Mol Cell Biol (1984) 1.55
Loss and stabilization of amplified dihydrofolate reductase genes in mouse sarcoma S-180 cell lines. Mol Cell Biol (1981) 1.42
Rapid spontaneous dihydrofolate reductase gene amplification shown by fluorescence-activated cell sorting. Proc Natl Acad Sci U S A (1983) 1.30
Gene amplification: an example of accelerated evolution in tumorigenic cells. Proc Natl Acad Sci U S A (1985) 1.19
Cell cycle distribution of chronically hypoxic cells and determination of the clonogenic potential of cells accumulated in G2 + M phases after irradiation of a solid tumor in vivo. Cancer Res (1979) 1.19
Increased gene amplification in L5178Y mouse lymphoma cells with hydroxyurea-induced chromosomal aberrations. Cancer Res (1985) 1.16
Amplification of sodium- and potassium-activated adenosinetriphosphatase in HeLa cells by ouabain step selection. J Cell Biol (1984) 1.14
Hamster cells with increased rates of DNA amplification, a new phenotype. Cell (1987) 1.11
Transient inhibition of DNA synthesis results in increased dihydrofolate reductase synthesis and subsequent increased DNA content per cell. Mol Cell Biol (1986) 1.09
Tumor necrosis can facilitate the appearance of metastases. Clin Exp Metastasis (1988) 1.06
Cell cycle dependency of metastatic lung colony formation. Cancer Res (1977) 1.05
Frequencies of independent and simultaneous selection of Chinese hamster cells for methotrexate and doxorubicin (adriamycin) resistance. Proc Natl Acad Sci U S A (1987) 1.02
Cell killing, radiosensitization and cell cycle redistribution induced by chronic hypoxia. Int J Radiat Oncol Biol Phys (1984) 1.01
Generation of drug-resistant variants in metastatic B16 mouse melanoma cell lines. Cancer Res (1987) 1.00
Effects of extreme hypoxia on the growth and viability of EMT6/SF mouse tumor cells in vitro. Cancer Res (1983) 0.98
Rapid emergence of methotrexate resistance in cultured mouse cells. Cancer Res (1984) 0.97
Over-replication of DNA in S phase Chinese hamster ovary cells after DNA synthesis inhibition. J Biol Chem (1987) 0.96
A fluid mechanical analysis of the velocity, adhesion, and destruction of cancer cells in capillaries during metastasis. Cell Biophys (1984) 0.96
Fifth Gordon Hamilton-Fairley memorial lecture. Methotrexate resistance and gene amplification: an experimental model for the generation of cellular heterogeneity. Br J Cancer (1985) 0.89
Mechanically induced trauma suffered by cancer cells in passing through pores in polycarbonate membranes. Invasion Metastasis (1985) 0.88
Cell cycle kinetics of aerated, hypoxic and re-aerated cells in vitro using flow cytometric determination of cellular DNA and incorporated bromodeoxyuridine. Cell Tissue Kinet (1985) 0.87
Enhancement of experimental metastasis by pretreatment of tumour cells with hydroxyurea. Int J Cancer (1986) 0.87
Tumor necrosis and cell detachment. Int J Cancer (1977) 0.87
Restimulation of cell cycle progression by hypoxic tumour cells with deoxynucleosides requires ppm oxygen tension. Exp Cell Res (1987) 0.87
Dynamic heterogeneity: isolation of murine tumor cell populations enriched for metastatic variants and quantification of the unstable expression of the phenotype. Clin Exp Metastasis (1986) 0.86
Measurement of low levels of oxygen and their effect on respiration in cell suspensions maintained in an open system. Radiat Res (1986) 0.85
Relationship between aberrant DNA replication and loss of cell viability in Chinese hamster ovary CHO-K1 cells. Cancer Res (1982) 0.83
Enhanced metastatic potential of murine fibrosarcomas treated in vitro with ultraviolet radiation. Cancer Res (1981) 0.83
DNA amplification and tumorigenicity of the human melanoma cell line MeWo. Cancer Res (1985) 0.81
Enhanced experimental metastatic capacity of a murine melanoma following pre-treatment with anticancer drugs. Clin Exp Metastasis (1987) 0.80
Cytogenetic evidence of gene amplification as a mechanism for tumor cell invasion. Somat Cell Mol Genet (1988) 0.80
DNA amplification and metastasis of the human melanoma cell line MeWo. Cancer Res (1987) 0.80
Effect of immunomodulation on the fate of tumor cells in the central nervous system and systemic organs of mice. Distribution of [125I]5-Iodo-2'-deoxyuridine-labeled KHT tumor cells after left intracardial injection. J Natl Cancer Inst (1982) 0.80
Shoplifting prevention: providing information through signs. J Appl Behav Anal (2010) 3.79
The response of hypoxic B16 melanoma cells to in vivo treatment with chemotherapeutic agents. Cancer Res (1975) 2.98
Tumor hypoxia has independent predictor impact only in patients with node-negative cervix cancer. J Clin Oncol (2002) 2.82
Oxygenation predicts radiation response and survival in patients with cervix cancer. Radiother Oncol (1998) 2.36
A lung-colony assay to determine the radiosensitivity of cells of a solid tumour. Int J Radiat Biol Relat Stud Phys Chem Med (1969) 2.27
Acute (cyclic) hypoxia enhances spontaneous metastasis of KHT murine tumors. Cancer Res (2001) 2.19
Effects of reoxygenation on cells from hypoxic regions of solid tumors: anticancer drug sensitivity and metastatic potential. J Natl Cancer Inst (1990) 2.12
Urgent endovascular revascularization for symptomatic intracranial atherosclerotic stenosis. Neurology (2003) 1.81
The evaluation of seizure disorders by computerized tomography. J Neurosurg (1979) 1.79
Cerebrovascular reactivity and vasospasm after subarachnoid hemorrhage: a pilot study. Neurology (2006) 1.78
'Steal' is an unestablished mechanism for the clinical presentation of cerebral arteriovenous malformations. Stroke (1995) 1.70
Characterization of image quality and image-guidance performance of a preclinical microirradiator. Med Phys (2011) 1.57
Molecular mechanisms of tumor invasion and metastasis: an integrated view. Curr Mol Med (2003) 1.54
Metabolic syndrome and cerebral vasomotor reactivity. Eur J Neurol (2010) 1.53
Glucose starvation and acidosis: effect on experimental metastatic potential, DNA content and MTX resistance of murine tumour cells. Br J Cancer (1991) 1.52
The potential role of HSP70 as an indicator of response to radiation and hyperthermia treatments for recurrent breast cancer. Int J Hyperthermia (1996) 1.49
The importance of the pre-irradiation breathing times of oxygen and carbogen (5% CO2: 95% O2) on the in vivo radiation response of a murine sarcoma. Int J Radiat Oncol Biol Phys (1978) 1.49
Variability in language recovery after first-time stroke. J Neurol Neurosurg Psychiatry (2007) 1.48
Partial volume rat lung irradiation: an evaluation of early DNA damage. Int J Radiat Oncol Biol Phys (1998) 1.45
The effect of anaemia on the fraction of hypoxic cells in an experimental tumour. Br J Radiol (1971) 1.41
The growing threat of AIDS: how marketers must respond. J Health Care Mark (1989) 1.39
Exposure to hypoxia, glucose starvation and acidosis: effect on invasive capacity of murine tumor cells and correlation with cathepsin (L + B) secretion. Clin Exp Metastasis (1997) 1.37
The use of rodent tumors in experimental cancer therapy. Conclusions and recommendations from an international workshop. Cancer Res (1985) 1.33
Mutator phenotype in Msh2-deficient murine embryonic fibroblasts. Cancer Res (1997) 1.31
The lung-colony assay: extension to the Lewis lung tumour and the B16 melanoma--radiosensitivity of B16 melanoma cells. Int J Radiat Biol Relat Stud Phys Chem Med (1975) 1.28
Cell cycle distribution of chronically hypoxic cells and determination of the clonogenic potential of cells accumulated in G2 + M phases after irradiation of a solid tumor in vivo. Cancer Res (1979) 1.19
Relationship of hypoxia to metastatic ability in rodent tumours. Br J Cancer (2001) 1.15
The p53 gene as a modifier of intrinsic radiosensitivity: implications for radiotherapy. Radiother Oncol (1996) 1.14
Gene expression in individual cells: analysis using global single cell reverse transcription polymerase chain reaction (GSC RT-PCR). Mutat Res (1999) 1.14
Ipsilateral motor dysfunction from unilateral stroke: implications for the functional neuroanatomy of hemiparesis. J Neurol Neurosurg Psychiatry (2007) 1.08
Analysis of genomic integrity and p53-dependent G1 checkpoint in telomerase-induced extended-life-span human fibroblasts. Mol Cell Biol (1999) 1.08
The response of C3H mammary tumours to irradiation in single and fractionated doses. Br J Radiol (1968) 1.07
Differential thermal sensitivity of tumour and normal tissue microvascular response during hyperthermia. Int J Hyperthermia (1992) 1.07
The relationship between elevated interstitial fluid pressure and blood flow in tumors: a bioengineering analysis. Int J Radiat Oncol Biol Phys (1999) 1.04
Combined radiotherapy--chemotherapy of Lewis lung carcinoma. Int J Radiat Oncol Biol Phys (1978) 1.04
Tumor biology. Am J Clin Oncol (1988) 1.04
An appraisal of in vivo assays of excised tumours. Br J Cancer Suppl (1980) 1.03
The effect of intercellular contact on the radiation sensitivity of KHT sarcoma cells. Radiat Res (1979) 1.02
Dynamic heterogeneity: rapid generation of metastatic variants in mouse B16 melanoma cells. Science (1984) 1.01
Generation of drug-resistant variants in metastatic B16 mouse melanoma cell lines. Cancer Res (1987) 1.00
Enhanced metastatic dissemination to multiple organs by melanoma and lymphoma cells in timp-3-/- mice. Oncogene (2006) 1.00
Early and late pulmonary toxicity in mice evaluated 180 and 420 days following localized lung irradiation. Radiat Res (1982) 1.00
Selective brain cooling with endovascular intracarotid infusion of cold saline: a pilot feasibility study. AJNR Am J Neuroradiol (2010) 1.00
Anemia, hypoxia and transfusion in patients with cervix cancer: a review. Radiother Oncol (2000) 0.99
Metastatic variants are generated spontaneously at a high rate in mouse KHT tumor. Proc Natl Acad Sci U S A (1982) 0.99
111In-labeled EGF is selectively radiotoxic to human breast cancer cells overexpressing EGFR. J Nucl Med (2000) 0.98
Comparing techniques of measuring tumor hypoxia in different murine tumors: Eppendorf pO2 Histograph, [3H]misonidazole binding and paired survival assay. Radiat Res (1996) 0.98
Time course of cholinesterase inhibition in adult rats treated acutely with carbaryl, carbofuran, formetanate, methomyl, methiocarb, oxamyl or propoxur. Toxicol Appl Pharmacol (2006) 0.97
Interhemispheric transfer of language in patients with left frontal cerebral arteriovenous malformation. Neuropsychologia (2000) 0.97
Audit commission tackles anaesthetic services. Anaesthesia should remain physician based service. BMJ (1998) 0.96
Heterogeneity of tumor oxygenation: relationship to tumor necrosis, tumor size, and metastasis. Int J Radiat Oncol Biol Phys (1998) 0.96
Dose fractionation studies with a murine sarcoma under conditions of air or carbogen (95% O2 + 5% CO2) breathing. Int J Radiat Oncol Biol Phys (1978) 0.95
Combining bioreductive drugs (SR 4233 or SN 23862) with the vasoactive agents flavone acetic acid or 5,6-dimethylxanthenone acetic acid. Int J Radiat Oncol Biol Phys (1994) 0.94
Quantitative genetic analysis of tumor progression. Cancer Metastasis Rev (1985) 0.93
Dynamic heterogeneity and metastasis. J Cell Physiol Suppl (1984) 0.93
Interstitial fluid pressure in cervical carcinoma: within tumor heterogeneity, and relation to oxygen tension. Cancer (1998) 0.93
Radiosensitivity, apoptosis and repair of DNA double-strand breaks in radiation-sensitive Chinese hamster ovary cell mutants treated at different dose rates. Radiat Res (1996) 0.93
Subcortical infarction resulting in acquired stuttering. J Neurol Neurosurg Psychiatry (2000) 0.92
Combined nitrogen mustard--radiation studies with a mouse tumor. Int J Radiat Oncol Biol Phys (1979) 0.91
Treatment of inoperable carotid aneurysms with endovascular carotid occlusion after extracranial-intracranial bypass surgery. Neurosurgery (1997) 0.91
Radiation sensitivity of tumour cells stained in vitro or in vivo with the bisbenzimide fluorochrome Hoechst 33342. Br J Cancer (1989) 0.91
An examination of the effects of hypoxia, acidosis, and glucose starvation on the expression of metastasis-associated genes in murine tumor cells. Clin Exp Metastasis (1997) 0.91
A new method of determining the fraction of hypoxic cells in a transplantable murine sarcoma. Radiat Res (1977) 0.90
The effect of misonidazole in combination with radiation dose fractionation. Br J Cancer Suppl (1978) 0.90
The in vivo radiation response of an experimental tumor: the effect of exposing tumor-bearing mice to a reduced oxygen environment prior to but not during irradiation. Int J Radiat Oncol Biol Phys (1979) 0.90
Activity of 4'-(9-acridinylamino)methanesulfon-m-anisidide against Chinese hamster cells in multicellular spheroids. Cancer Res (1981) 0.90
Comparison between in vitro radiosensitivity and in vivo radioresponse in murine tumor cell lines. II: In vivo radioresponse following fractionated treatment and in vitro/in vivo correlations. Int J Radiat Oncol Biol Phys (1990) 0.90
The p53-mediated G1 checkpoint is retained in tumorigenic rat embryo fibroblast clones transformed by the human papillomavirus type 16 E7 gene and EJ-ras. Mol Cell Biol (1995) 0.90
Re-irradiation tolerance in the rat spinal cord: influence of level of initial damage. Radiother Oncol (1993) 0.90
Detection of hypoxic fractions in murine tumors by comet assay: comparison with other techniques. Radiat Res (1995) 0.89
Factors affecting hypoxic KHT tumor cells in mice breathing O2, O2 + CO2 , or hyperbaric oxygen with or without anesthesia. Radiology (1973) 0.89
A quantitative analysis of the reduction in oxygen levels required to induce up-regulation of vascular endothelial growth factor (VEGF) mRNA in cervical cancer cell lines. Br J Cancer (1999) 0.88
In-field and out-of-field effects in partial volume lung irradiation in rodents: possible correlation between early dna damage and functional endpoints. Int J Radiat Oncol Biol Phys (2000) 0.87
Modification of the cytotoxic activity of mitomycin C by oxygen and ascorbic acid in Chinese hamster ovary cells and a repair-deficient mutant. Cancer Res (1986) 0.87
Linear-quadratic model underestimates sparing effect of small doses per fraction in rat spinal cord. Radiother Oncol (1992) 0.87
A comparison of the response of tumour and normal tissue in the mouse exposed to single doses of fast neutrons or electrons. Br J Radiol (1970) 0.86
Clinical and morphological determinants of focal neurological deficits in patients with unruptured brain arteriovenous malformation. J Neurol Sci (2009) 0.86
Dynamic heterogeneity: isolation of murine tumor cell populations enriched for metastatic variants and quantification of the unstable expression of the phenotype. Clin Exp Metastasis (1986) 0.86
Tumor heterogeneity and stability of the metastatic phenotype of mouse KHT sarcoma cells. Cancer Res (1981) 0.86
Heterogeneity of polarographic oxygen tension measurements in cervix cancer: an evaluation of within and between tumor variability, probe position, and track depth. Int J Radiat Oncol Biol Phys (1997) 0.86
Neurobehavioral effects of chronic dietary and repeated high-level spike exposure to chlorpyrifos in rats. Toxicol Sci (2005) 0.86
Mitigation of radiation-induced lung injury with EUK-207 and genistein: effects in adolescent rats. Radiat Res (2012) 0.85
Radiobiological studies of cells in multicellular spheroids using a sequential trypsinization technique. Radiat Res (1981) 0.85
Mitigation of lung injury after accidental exposure to radiation. Radiat Res (2011) 0.85
Anterior translocation of language in patients with left cerebral arteriovenous malformation. Neurology (1997) 0.85
Measurement of low levels of oxygen and their effect on respiration in cell suspensions maintained in an open system. Radiat Res (1986) 0.85
Pulmonary metastases of the lewis lung tumor-cell kinetics and response to cyclophosphamide at different sizes. Cancer Treat Rep (1977) 0.84
Intradermal injection of autologous dermal fibroblasts improves wound healing in irradiated skin. J Surg Res (1999) 0.84
Sensitizers and radiation dose fractionation: results and interpretations. Int J Radiat Oncol Biol Phys (1986) 0.84
A comparison in individual murine tumors of techniques for measuring oxygen levels. Int J Radiat Oncol Biol Phys (1999) 0.84
Toxicity of 4'-(9-acridinylamino)methanesulfon-m-anisidide in exponential- and plateau-phase Chinese hamster cell cultures. Cancer Res (1981) 0.83
Effects of reoxygenation on cells from hypoxic regions of solid tumors: analysis of transplanted murine tumors for evidence of DNA overreplication. Cancer Res (1990) 0.81
Comparison between in vitro radiosensitivity and in vivo radioresponse of murine tumor cell lines. I: Parameters of in vitro radiosensitivity and endogenous cellular glutathione levels. Int J Radiat Oncol Biol Phys (1990) 0.81
Cellular approaches to bioreductive drug mechanisms. Cancer Metastasis Rev (1993) 0.81
Hypoxia signaling and the metastatic phenotype. Curr Mol Med (2014) 0.81
Cervix cancer oxygenation measured following external radiation therapy. Int J Radiat Oncol Biol Phys (1998) 0.81
Mutant p53 increases radioresistance in rat embryo fibroblasts simultaneously transfected with HPV16-E7 and/or activated H-ras. Oncogene (1994) 0.81
Motor behavior in stroke patients with isolated medial frontal ischemic infarction. Stroke (1997) 0.80
Analysis of blood gas values in mice following pulmonary irradiation. Radiat Res (1980) 0.80
Repopulation kinetics during fractionated irradiation and the relationship to the potential doubling time, Tpot. Int J Radiat Oncol Biol Phys (1995) 0.80