Published in Cell on May 01, 1977
Linkage map of Escherichia coli K-12, edition 6. Microbiol Rev (1980) 27.40
Evidence for a chromosome-borne resistance transposon (Tn916) in Streptococcus faecalis that is capable of "conjugal" transfer in the absence of a conjugative plasmid. J Bacteriol (1981) 11.15
A highly polymorphic locus in human DNA. Proc Natl Acad Sci U S A (1980) 10.27
Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene. Proc Natl Acad Sci U S A (1979) 9.31
Molecular model for the transposition and replication of bacteriophage Mu and other transposable elements. Proc Natl Acad Sci U S A (1979) 7.80
Structure of a cloned circular Moloney murine leukemia virus DNA molecule containing an inverted segment: implications for retrovirus integration. Proc Natl Acad Sci U S A (1980) 6.73
The RAD52 gene is required for homothallic interconversion of mating types and spontaneous mitotic recombination in yeast. Proc Natl Acad Sci U S A (1980) 6.50
Properties of erythromycin-inducible transposon Tn917 in Streptococcus faecalis. J Bacteriol (1980) 6.06
In vitro mutagenesis of a circular DNA molecule by using synthetic restriction sites. Proc Natl Acad Sci U S A (1978) 5.32
Structure of the joint region and the termini of the DNA of herpes simplex virus type 1. J Virol (1978) 4.62
Recombination-deficient mutant of Streptococcus faecalis. J Bacteriol (1980) 4.60
Molecular genetics of bacteriophage P22. Microbiol Rev (1978) 4.51
Characterization of Tn904 insertions in octopine Ti plasmid mutants of Agrobacterium tumefaciens. J Bacteriol (1980) 4.14
Association of adhesive, invasive, and virulent phenotypes of Salmonella typhimurium with autonomous 60-megadalton plasmids. Infect Immun (1982) 4.10
Intramolecular integration within Moloney murine leukemia virus DNA. J Virol (1981) 3.77
Structure of Moloney murine leukemia viral DNA: nucleotide sequence of the 5' long terminal repeat and adjacent cellular sequences. Proc Natl Acad Sci U S A (1980) 3.53
Physical characterization of Bacteroides fragilis R plasmid pBF4. J Bacteriol (1981) 3.46
Genetic organization of the broad-host-range IncP-1 plasmid R751. J Bacteriol (1980) 3.38
T-DNA from Agrobacterium Ti plasmid is in the nuclear DNA fraction of crown gall tumor cells. Proc Natl Acad Sci U S A (1980) 3.32
Selfish DNA: a sexually-transmitted nuclear parasite. Genetics (1983) 3.31
Conjugal transfer system of the IncN plasmid pKM101. J Bacteriol (1985) 3.03
Mechanisms of microbial resistance and detoxification of mercury and organomercury compounds: physiological, biochemical, and genetic analyses. Microbiol Rev (1984) 2.97
Nucleotide sequence of Moloney leukemia virus: 3' end reveals details of replications, analogy to bacterial transposons, and an unexpected gene. Proc Natl Acad Sci U S A (1980) 2.90
A physical genome map of Pseudomonas aeruginosa PAO. EMBO J (1989) 2.60
Transposition of plasmid DNA segments specifying hydrocarbon degradation and their expression in various microorganisms. Proc Natl Acad Sci U S A (1978) 2.55
The integrons In0, In2, and In5 are defective transposon derivatives. J Bacteriol (1996) 2.53
Transposition of the Escherichia coli insertion element gamma generates a five-base-pair repeat. Proc Natl Acad Sci U S A (1979) 2.47
Isolation and characterization of cloned human DNA fragments carrying reiterated sequences common to both autosomes and the X chromosome. Nucleic Acids Res (1981) 2.41
Specificity of insertion by the translocatable tetracycline-resistance element Tn10. Genetics (1979) 2.41
Transposon A-generated mutations in the mercuric resistance genes of plasmid R100-1. J Bacteriol (1979) 2.33
Coordinated regulation of octopine degradation and conjugative transfer of Ti plasmids in Agrobacterium tumefaciens: evidence for a common regulatory gene and separate operons. J Bacteriol (1978) 2.14
Integration and transcription of mouse mammary tumor virus DNA in rat hepatoma cells. Proc Natl Acad Sci U S A (1979) 2.08
The 10 kb Drosophila virilis 28S rDNA intervening sequence is flanked by a direct repeat of 14 base pairs of coding sequence. Nucleic Acids Res (1980) 2.05
The 5' termini of RNAs encoded by the transposable element copia. Nucleic Acids Res (1981) 1.89
Transposition of the oxacillin-hydrolyzing penicillinase gene. J Bacteriol (1981) 1.82
Characterization of endogenous and exogenous mouse mammary tumor virus proviral DNA with site-specific molecular clones. J Virol (1980) 1.80
Translation and developmental regulation of RNA encoded by the eukaryotic transposable element copia. Proc Natl Acad Sci U S A (1980) 1.80
Regulation of Tn5 transposition in Salmonella typhimurium. Proc Natl Acad Sci U S A (1980) 1.76
Sequence of 1019 nucleotides encompassing one of the inverted repeats from the yeast 2 micrometer plasmid. Nucleic Acids Res (1979) 1.74
Entry exclusion determinant(s) of IncN plasmid pKM101. J Bacteriol (1985) 1.71
Circularization of transduced fragments: a mechanism for adding segments to the bacterial chromosome. Genetics (1980) 1.69
Physical analysis of the CYC1-sup4 interval in Saccharomyces cerevisiae. Mol Cell Biol (1981) 1.68
mRNAs for the immobilization antigens of Paramecium. Proc Natl Acad Sci U S A (1981) 1.67
Escherichia coli heat-labile enterotoxin genes are flanked by repeated deoxyribonucleic acid sequences. J Bacteriol (1981) 1.67
A cDNA clone from Zea mays endosperm sucrose synthetase mRNA. Nucleic Acids Res (1980) 1.67
Complete nucleotide sequence of insertion element IS4351 from Bacteroides fragilis. J Bacteriol (1987) 1.66
Characterization of insertion sequence IS946, an Iso-ISS1 element, isolated from the conjugative lactococcal plasmid pTR2030. J Bacteriol (1990) 1.63
Terminally redundant sequences in cellular intracisternal A-particle genes. J Virol (1981) 1.57
Stimulation of deletions in the Escherichia coli chromosome by partially induced Mucts62 prophages. J Bacteriol (1978) 1.51
Transposition of Tn904 encoding streptomycin resistance into the octopine Ti plasmid of Agrobacterium tumefaciens. J Bacteriol (1980) 1.45
Nucleotide sequences at the ends of the mercury resistance transposon, Tn501. Nucleic Acids Res (1980) 1.37
Cloning of deoxyribonucleic acid regions encoding a heat-labile and heat-stable enterotoxin originating from an enterotoxigenic Escherichia coli strain of human origin. J Bacteriol (1980) 1.34
Gene-sized DNA molecules of the Oxytricha macronucleus have the same terminal sequence. Proc Natl Acad Sci U S A (1977) 1.34
Origins of metabolic diversity: evolutionary divergence by sequence repetition. Proc Natl Acad Sci U S A (1979) 1.33
Adjacent insertion sequences IS2 and IS5 in bacteriophage Mu mutants and an IS5 in a lambda darg bacteriophage. J Bacteriol (1978) 1.32
Isolation and characterization of enterotoxin-deficient mutants of Escherichia coli. Proc Natl Acad Sci U S A (1978) 1.31
Structure of a naturally occurring plasmid with genes for enterotoxin production and drug resistance. J Bacteriol (1981) 1.29
Organization of a hybrid between phage f1 and plasmid pSC101. Proc Natl Acad Sci U S A (1979) 1.28
Mutagenesis by insertion of drug resistance transposon Tn7 into a vibrio species. J Bacteriol (1981) 1.28
Additive recombination in bacteria. Bacteriol Rev (1977) 1.26
Common plasmid specifying tobramycin resistance found in two enteric bacteria isolated from burn patients. Antimicrob Agents Chemother (1978) 1.23
Deoxyribonucleic acid sequence homologies among bacterial insertion sequence elements and genomes of various organisms. J Bacteriol (1979) 1.22
Vibrio cholerae hybrid sex factor that contains ampicillin transposon Tn1. J Bacteriol (1979) 1.21
chlC (nar) operon of Escherichia coli includes structural genes for alpha and beta subunits of nitrate reductase. J Bacteriol (1983) 1.20
Small circular DNA of Drosophila melanogaster: chromosomal homology and kinetic complexity. Proc Natl Acad Sci U S A (1979) 1.18
Plasmids and transposable elements in Salmonella wien. J Bacteriol (1979) 1.17
Effect of temperature on translocation frequency of the Tn3 element. J Bacteriol (1979) 1.15
Control of expression of a cloned yeast (Saccharomyces cerevisiae) gene (trp5) by a bacterial insertion element (IS2). Proc Natl Acad Sci U S A (1978) 1.14
Increased mutation in crosses between geographically separated strains of Drosophila melanogaster. Proc Natl Acad Sci U S A (1980) 1.13
Simultaneous loss of multiple differentiated functions in aerial mycelium-negative isolates of streptomycetes. J Bacteriol (1979) 1.08
DNA sequences of the integration sites and inverted repeated structure of transposon Tn3. Nucleic Acids Res (1979) 1.08
Bacillus stearothermophilus contains a plasmid-borne gene for alpha-amylase. Proc Natl Acad Sci U S A (1983) 1.00
Transposon-facilitated chromosome mobilization in Agrobacterium tumefaciens. J Bacteriol (1983) 0.99
A complex repeated DNA sequence within the Drosophila transposable element copia. Nucleic Acids Res (1981) 0.98
Location of an ampicillin resistance transposon, Tn1701, in a group of small, nontransferring plasmids. J Bacteriol (1979) 0.98
In vitro construction of deletion mutants of the bacteriocinogenic plasmid Clo DF13. Nucleic Acids Res (1978) 0.98
Isolation and characterization of a highly repetitious inverted terminal repeat sequence from Oxytricha macronuclear DNA. Proc Natl Acad Sci U S A (1978) 0.97
Isolation and characterization of spontaneously arising auxotrophic and Kanagawa phenomenon-negative mutants of Vibrio parahaemolyticus. Infect Immun (1980) 0.95
A genetic approach to analysis of transposons. Proc Natl Acad Sci U S A (1979) 0.94
Fate of donor insertion sequence IS1 during transposition. Proc Natl Acad Sci U S A (1980) 0.93
Site-specific recombination between plasmids of Staphylococcus aureus. J Bacteriol (1980) 0.91
Modulation of protein A formation in Staphylococcus aureus by genetic determinants for methicillin resistance. J Bacteriol (1979) 0.88
Structure and function of repetitive DNA in eukaryotes. Biochem J (1986) 0.86
Cell-cycle-associated rearrangement of inverted repeat DNA sequences. Proc Natl Acad Sci U S A (1979) 0.86
Propagation of restriction fragments from the mitochondrial DNA of Saccharomyces cerevisiae in E. coli by means of plasmid vectors. Nucleic Acids Res (1979) 0.86
Construction of an IS946-based composite transposon in Lactococcus lactis subsp. lactis. J Bacteriol (1991) 0.84
Clustering and methylation of repeated DNA: persistence in avian development and evolution. Nucleic Acids Res (1981) 0.83
Spontaneous phase variation in Bordetella pertussis is a multistep non-random process. EMBO J (1984) 0.82
Characterization of a cis-acting regulatory mutation that maps at the distal end of the Escherichia coli glyA gene. J Bacteriol (1985) 0.82
DNA sequence of the excision sites of a mitochondrial plasmid from senescent Podospora anserina. Nucleic Acids Res (1983) 0.82
Knockout of an outer membrane protein operon of Anaplasma marginale by transposon mutagenesis. BMC Genomics (2014) 0.81
New translocation sequence mediating tetracycline resistance found in Escherichia coli pathogenic for piglets. Antimicrob Agents Chemother (1980) 0.79
Physical evidence for a Saccharomyces cerevisiae transposable element which carries the his4C gene. Mol Cell Biol (1981) 0.79
Isolation of F' plasmids carrying a portion of the Salmonella typhimurium histidine transport operon. J Bacteriol (1984) 0.77
Possible involvement of a plasmid in arginine auxotrophic mutation of Streptomyces kasugaensis. J Bacteriol (1980) 0.76
Location of ribosome-binding sites on the tetracycline resistance transposon Tn10. J Bacteriol (1978) 0.76
Improved single and multicopy lac-based cloning vectors for protein and operon fusions. Gene (1987) 24.38
Genetic engineering in vivo using translocatable drug-resistance elements. New methods in bacterial genetics. J Mol Biol (1977) 20.29
New Tn10 derivatives for transposon mutagenesis and for construction of lacZ operon fusions by transposition. Gene (1984) 17.36
A method for gene disruption that allows repeated use of URA3 selection in the construction of multiply disrupted yeast strains. Genetics (1987) 14.69
Transposable elements in prokaryotes. Annu Rev Genet (1981) 13.41
Mutagenesis by insertion of a drug-resistance element carrying an inverted repetition. J Mol Biol (1975) 11.14
DMC1: a meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression. Cell (1992) 10.48
Meiosis-specific DNA double-strand breaks are catalyzed by Spo11, a member of a widely conserved protein family. Cell (1997) 10.32
A pathway for generation and processing of double-strand breaks during meiotic recombination in S. cerevisiae. Cell (1990) 9.24
Uses of transposons with emphasis on Tn10. Methods Enzymol (1991) 8.13
Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombination. Cell (1990) 7.85
Meiotic chromosomes: integrating structure and function. Annu Rev Genet (1999) 7.33
Properties of the translocatable tetracycline-resistance element Tn10 in Escherichia coli and bacteriophage lambda. Genetics (1978) 6.73
Temporal comparison of recombination and synaptonemal complex formation during meiosis in S. cerevisiae. Cell (1991) 6.15
Genetic organization of transposon Tn10. Cell (1981) 6.04
The single-end invasion: an asymmetric intermediate at the double-strand break to double-holliday junction transition of meiotic recombination. Cell (2001) 5.94
Translational control of IS10 transposition. Cell (1983) 4.94
Identification of double Holliday junctions as intermediates in meiotic recombination. Cell (1995) 4.82
IS10 transposition is regulated by DNA adenine methylation. Cell (1985) 4.41
A symmetrical six-base-pair target site sequence determines Tn10 insertion specificity. Cell (1982) 4.36
Interhomolog bias during meiotic recombination: meiotic functions promote a highly differentiated interhomolog-only pathway. Cell (1997) 4.30
Chromosome pairing via multiple interstitial interactions before and during meiosis in yeast. Cell (1994) 4.23
Cohesins bind to preferential sites along yeast chromosome III, with differential regulation along arms versus the centric region. Cell (1999) 4.17
The leptotene-zygotene transition of meiosis. Annu Rev Genet (1998) 4.06
DNA sequence organization of IS10-right of Tn10 and comparison with IS10-left. Proc Natl Acad Sci U S A (1982) 4.05
Identification of joint molecules that form frequently between homologs but rarely between sister chromatids during yeast meiosis. Cell (1994) 4.04
Three promoters near the termini of IS10: pIN, pOUT, and pIII. Cell (1983) 3.92
E. coli oriC and the dnaA gene promoter are sequestered from dam methyltransferase following the passage of the chromosomal replication fork. Cell (1990) 3.87
NDT80, a meiosis-specific gene required for exit from pachytene in Saccharomyces cerevisiae. Mol Cell Biol (1995) 3.82
Three Tn10-associated excision events: relationship to transposition and role of direct and inverted repeats. Cell (1981) 3.81
SeqA: a negative modulator of replication initiation in E. coli. Cell (1994) 3.65
Tn10 transposase acts preferentially on nearby transposon ends in vivo. Cell (1983) 3.23
Biological regulation by antisense RNA in prokaryotes. Annu Rev Genet (1988) 3.11
Meiotic cells monitor the status of the interhomolog recombination complex. Genes Dev (1997) 2.95
A Tn10-lacZ-kanR-URA3 gene fusion transposon for insertion mutagenesis and fusion analysis of yeast and bacterial genes. Genetics (1987) 2.66
Inversions and deletions of the Salmonella chromosome generated by the translocatable tetracycline resistance element Tn10. J Mol Biol (1979) 2.65
The yeast RAD50 gene encodes a predicted 153-kD protein containing a purine nucleotide-binding domain and two large heptad-repeat regions. Genetics (1989) 2.63
Covalent protein-DNA complexes at the 5' strand termini of meiosis-specific double-strand breaks in yeast. Proc Natl Acad Sci U S A (1995) 2.56
Sequence non-specific double-strand breaks and interhomolog interactions prior to double-strand break formation at a meiotic recombination hot spot in yeast. EMBO J (1995) 2.52
Tn10 transposition and circle formation in vitro. Cell (1987) 2.46
Specificity of insertion by the translocatable tetracycline-resistance element Tn10. Genetics (1979) 2.41
Progression of meiotic DNA replication is modulated by interchromosomal interaction proteins, negatively by Spo11p and positively by Rec8p. Genes Dev (2000) 2.34
Synaptonemal complex (SC) component Zip1 plays a role in meiotic recombination independent of SC polymerization along the chromosomes. Proc Natl Acad Sci U S A (1996) 2.29
Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction. Proc Natl Acad Sci U S A (1999) 2.25
DNA sequence analysis of Tn10 insertions: origin and role of 9 bp flanking repetitions during Tn10 translocation. Cell (1979) 2.24
Saccharomyces cerevisiae recA homologues RAD51 and DMC1 have both distinct and overlapping roles in meiotic recombination. Genes Cells (1997) 2.18
Physical structures of Tn10-promoted deletions and inversions: role of 1400 bp inverted repetitions. Cell (1979) 2.16
Tn10 transposition via a DNA hairpin intermediate. Cell (1998) 2.05
Genetic evidence that Tn10 transposes by a nonreplicative mechanism. Cell (1986) 2.05
Mutational analysis of IS10's outside end. EMBO J (1989) 2.03
Coordinating DNA replication initiation with cell growth: differential roles for DnaA and SeqA proteins. Proc Natl Acad Sci U S A (1996) 1.88
Intramolecular transposition by Tn10. Cell (1989) 1.87
IS10 transposase mutations that specifically alter target site recognition. EMBO J (1992) 1.84
Structural relationship of bacterial RecA proteins to recombination proteins from bacteriophage T4 and yeast. Science (1993) 1.83
A specific class of IS10 transposase mutants are blocked for target site interactions and promote formation of an excised transposon fragment. Cell (1989) 1.81
Meiotic chromosomes move by linkage to dynamic actin cables with transduction of force through the nuclear envelope. Cell (2008) 1.80
RAD50 protein of S.cerevisiae exhibits ATP-dependent DNA binding. Nucleic Acids Res (1993) 1.76
Somatic pairing of homologs in budding yeast: existence and modulation. Genes Dev (1999) 1.71
Tn10/IS10 transposase purification, activation, and in vitro reaction. J Biol Chem (1994) 1.70
Transposase promotes double strand breaks and single strand joints at Tn10 termini in vivo. Cell (1984) 1.68
Insertion sequence IS10 anti-sense pairing initiates by an interaction between the 5' end of the target RNA and a loop in the anti-sense RNA. J Mol Biol (1989) 1.65
Kinetic and structural analysis of a cleaved donor intermediate and a strand transfer intermediate in Tn10 transposition. Cell (1991) 1.65
Mismatch repair mutations of Escherichia coli K12 enhance transposon excision. Genetics (1985) 1.62
Tn10 insertion specificity is strongly dependent upon sequences immediately adjacent to the target-site consensus sequence. Proc Natl Acad Sci U S A (1992) 1.62
Identification and characterization of a pre-cleavage synaptic complex that is an early intermediate in Tn10 transposition. EMBO J (1995) 1.55
Essential sites at transposon Tn 10 termini. Proc Natl Acad Sci U S A (1984) 1.55
Unusual alleles of recB and recC stimulate excision of inverted repeat transposons Tn10 and Tn5. Proc Natl Acad Sci U S A (1984) 1.53
The three chemical steps of Tn10/IS10 transposition involve repeated utilization of a single active site. Cell (1996) 1.52
Excision of Tn10 from the donor site during transposition occurs by flush double-strand cleavages at the transposon termini. Proc Natl Acad Sci U S A (1992) 1.50
Crossover and noncrossover recombination during meiosis: timing and pathway relationships. Proc Natl Acad Sci U S A (1995) 1.49
Molecular cloning and characterization of the pgm gene encoding phosphoglucomutase of Escherichia coli. J Bacteriol (1994) 1.47
Tn10 protects itself at two levels from fortuitous activation by external promoters. Cell (1985) 1.43
A new type of fusion analysis applicable to many organisms: protein fusions to the URA3 gene of yeast. Genetics (1987) 1.42
Communication between homologous chromosomes: genetic alterations at a nuclease-hypersensitive site can alter mitotic chromatin structure at that site both in cis and in trans. Genes Cells (1996) 1.42
Physical analysis of Tn10- and IS10-promoted transpositions and rearrangements. Genetics (1987) 1.40
IHF modulation of Tn10 transposition: sensory transduction of supercoiling status via a proposed protein/DNA molecular spring. Cell (1998) 1.39
Collisions between yeast chromosomal loci in vivo are governed by three layers of organization. Genes Dev (1999) 1.37
Translocation and other recombination events involving the tetracycline-resistance element Tn10. Cold Spring Harb Symp Quant Biol (1979) 1.33
A new generalizable test for detection of mutations affecting Tn10 transposition. Genetics (1987) 1.31
IS10/Tn10 transposition efficiently accommodates diverse transposon end configurations. EMBO J (1996) 1.29
Single molecule detection of direct, homologous, DNA/DNA pairing. Proc Natl Acad Sci U S A (2009) 1.27
Mutations in Saccharomyces cerevisiae that block meiotic prophase chromosome metabolism and confer cell cycle arrest at pachytene identify two new meiosis-specific genes SAE1 and SAE3. Genetics (1997) 1.25
Tn10 transposition promotes RecA-dependent induction of a lambda prophage. Proc Natl Acad Sci U S A (1988) 1.23
Genetic characterization of plasmid formation by N- mutants of bacteriophage lambda. Virology (1977) 1.21
Nearly precise excision: a new type of DNA alteration associated with the translocatable element Tn10. Cell (1979) 1.20
Mechanism and regulation of Tn10 transposition. Cold Spring Harb Symp Quant Biol (1984) 1.19
The unusual stability of the IS10 anti-sense RNA is critical for its function and is determined by the structure of its stem-domain. EMBO J (1989) 1.19
GCN5-dependent histone H3 acetylation and RPD3-dependent histone H4 deacetylation have distinct, opposing effects on IME2 transcription, during meiosis and during vegetative growth, in budding yeast. Proc Natl Acad Sci U S A (1999) 1.19
Multiple IS10 rearrangements in Escherichia coli. J Mol Biol (1984) 1.17
Tn 10 transposition in vivo: temporal separation of cleavages at the two transposon ends and roles of terminal basepairs subsequent to interaction of ends. EMBO J (1994) 1.15
The Tn10 synaptic complex can capture a target DNA only after transposon excision. Cell (1997) 1.13
recA-dependent genetic switch generated by transposon Tn10. J Mol Biol (1980) 1.10
Quantitation of insertion sequence IS10 transposase gene expression by a method generally applicable to any rarely expressed gene. Proc Natl Acad Sci U S A (1986) 1.08
Gamma-H2AX illuminates meiosis. Nat Genet (2001) 1.08
IS10 mRNA stability and steady state levels in Escherichia coli: indirect effects of translation and role of rne function. Mol Microbiol (1993) 1.07
Efficient Tn10 transposition into a DNA insertion hot spot in vivo requires the 5-methyl groups of symmetrically disposed thymines within the hot-spot consensus sequence. Proc Natl Acad Sci U S A (1987) 1.06
The two single-strand cleavages at each end of Tn10 occur in a specific order during transposition. Proc Natl Acad Sci U S A (1995) 1.02