Published in J Cell Biol on October 01, 1982
Changes in lysosome shape and distribution correlated with changes in cytoplasmic pH. J Cell Biol (1989) 3.23
Changes in cytosolic pH and calcium of guard cells precede stomatal movements. Proc Natl Acad Sci U S A (1992) 3.01
The effects of metabolic inhibition on intracellular calcium and pH in isolated rat ventricular cells. J Physiol (1989) 2.86
Role of outer membrane barrier in efflux-mediated tetracycline resistance of Escherichia coli. J Bacteriol (1995) 2.52
A Novel Method for Continuous Determination of the Intracellular pH in Bacteria with the Internally Conjugated Fluorescent Probe 5 (and 6-)-Carboxyfluorescein Succinimidyl Ester. Appl Environ Microbiol (1996) 2.52
A novel tumour promoter, thapsigargin, transiently increases cytoplasmic free Ca2+ without generation of inositol phosphates in NG115-401L neuronal cells. Biochem J (1988) 2.49
Fluorescence ratio imaging microscopy: temporal and spatial measurements of cytoplasmic pH. J Cell Biol (1987) 2.28
Cytoplasmic pH regulation in thymic lymphocytes by an amiloride-sensitive Na+/H+ antiport. J Gen Physiol (1984) 2.23
Endothelin stimulates phospholipase C, Na+/H+ exchange, c-fos expression, and mitogenesis in rat mesangial cells. J Clin Invest (1989) 2.17
Effect of M1 protein and low pH on nuclear transport of influenza virus ribonucleoproteins. J Virol (1996) 2.08
Nuclear Ca2+ concentration measured with specifically targeted recombinant aequorin. EMBO J (1993) 1.98
Regulation of intracellular pH in eukaryotic cells. Biochem J (1988) 1.94
Internal pH changes associated with the activity of NADPH oxidase of human neutrophils. Further evidence for the presence of an H+ conducting channel. Biochem J (1988) 1.88
Microspectrofluorometry by digital image processing: measurement of cytoplasmic pH. J Cell Biol (1984) 1.84
Mapping of fluorescence anisotropy in living cells by ratio imaging. Application to cytoplasmic viscosity. Biophys J (1990) 1.72
Cell pH in the rat proximal convoluted tubule. Regulation by luminal and peritubular pH and sodium concentration. J Clin Invest (1986) 1.68
Potent leukocidal action of Escherichia coli hemolysin mediated by permeabilization of target cell membranes. J Exp Med (1989) 1.60
Calcium and proton activities in rat cardiac mitochondria. Effect of matrix environment on behaviour of fluorescent probes. Biochem J (1989) 1.60
Intracellular pH during "chemical hypoxia" in cultured rat hepatocytes. Protection by intracellular acidosis against the onset of cell death. J Clin Invest (1989) 1.53
The efflux of a fluorescent probe is catalyzed by an ATP-driven extrusion system in Lactococcus lactis. J Bacteriol (1992) 1.46
Myoplasmic calcium transients monitored with purpurate indicator dyes injected into intact frog skeletal muscle fibers. J Gen Physiol (1991) 1.44
Kinetics of endosome acidification in mutant and wild-type Chinese hamster ovary cells. J Cell Biol (1987) 1.42
pH regulation in single CA1 neurons acutely isolated from the hippocampi of immature and mature rats. J Physiol (1996) 1.41
Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms. Cell (2017) 1.38
Changes of intracellular pH due to repetitive stimulation of single fibres from mouse skeletal muscle. J Physiol (1992) 1.37
Microinjection of ras p21 induces a rapid rise in intracellular pH. Mol Cell Biol (1987) 1.36
Maintenance of Intracellular pH and Acid Tolerance in Rhizobium meliloti. Appl Environ Microbiol (1989) 1.36
The internal pH of the forespore compartment of Bacillus megaterium decreases by about 1 pH unit during sporulation. J Bacteriol (1994) 1.33
Two-photon fluorescence lifetime imaging of the skin stratum corneum pH gradient. Biophys J (2002) 1.33
Effects of metabolic blockade on the regulation of intracellular calcium in dissociated mouse sensory neurones. J Physiol (1990) 1.33
Na+-H+ exchange in gastric glands as measured with a cytoplasmic-trapped, fluorescent pH indicator. Proc Natl Acad Sci U S A (1984) 1.32
Extracellular acidosis is a novel danger signal alerting innate immunity via the NLRP3 inflammasome. J Biol Chem (2013) 1.31
pH-induced microtubule-dependent redistribution of late endosomes in neuronal and epithelial cells. J Cell Biol (1991) 1.31
Diarylsulfones, a new chemical class of nonnucleoside antiviral inhibitors of human immunodeficiency virus type 1 reverse transcriptase. Antimicrob Agents Chemother (1993) 1.30
Intracellular calibration of a pH-sensitive dye in isolated, perfused salamander proximal tubules. J Gen Physiol (1985) 1.28
Electrophysiology of glutamate and sodium co-transport in a glial cell of the salamander retina. J Physiol (1990) 1.25
Human Rhesus B and Rhesus C glycoproteins: properties of facilitated ammonium transport in recombinant kidney cells. Biochem J (2005) 1.23
Diffusion coefficient of cyclic GMP in salamander rod outer segments estimated with two fluorescent probes. Biophys J (1993) 1.22
Spreading of HeLa cells on a collagen substratum requires a second messenger formed by the lipoxygenase metabolism of arachidonic acid released by collagen receptor clustering. Mol Biol Cell (1992) 1.22
Functional expression and subcellular localization of an anion exchanger cloned from choroid plexus. Proc Natl Acad Sci U S A (1990) 1.21
Measurements of intracellular Ca2+ in dissociated type I cells of the rabbit carotid body. J Physiol (1989) 1.21
Apical Na+/H+ antiporter and glycolysis-dependent H+-ATPase regulate intracellular pH in the rabbit S3 proximal tubule. J Clin Invest (1987) 1.19
Keratins modulate colonocyte electrolyte transport via protein mistargeting. J Cell Biol (2004) 1.18
Proton sensitivity of the GABA(A) receptor is associated with the receptor subunit composition. J Physiol (1996) 1.16
Cytoplasmic pH regulation and chloride/bicarbonate exchange in avian osteoclasts. J Clin Invest (1989) 1.16
Cytosolic alkalinization mediated by abscisic Acid is necessary, but not sufficient, for abscisic Acid-induced gene expression in barley aleurone protoplasts. Plant Physiol (1992) 1.16
Role of lysosomal and cytosolic pH in the regulation of macrophage lysosomal enzyme secretion. Biochem J (1990) 1.15
Envelope glycoprotein gp120 of human immunodeficiency virus type 1 alters ion transport in astrocytes: implications for AIDS dementia complex. Proc Natl Acad Sci U S A (1994) 1.14
Influence of P-glycoprotein inhibitors on accumulation of macrolides in J774 murine macrophages. Antimicrob Agents Chemother (2003) 1.14
The Bacteroides by-product succinic acid inhibits neutrophil respiratory burst by reducing intracellular pH. Infect Immun (1987) 1.13
Characterization of acid extrusion mechanisms in cultured fetal rat hippocampal neurones. J Physiol (1996) 1.12
Effect of common agonists on cytoplasmic ionized calcium concentration in platelets. Measurement with 2-methyl-6-methoxy 8-nitroquinoline (quin2) and aequorin. J Clin Invest (1986) 1.12
The Light-Dependent Transduction Pathway Controlling the Regulatory Phosphorylation of C4 Phosphoenolpyruvate Carboxylase in Protoplasts from Digitaria sanguinalis. Plant Cell (1996) 1.09
Cholangiocyte anion exchange and biliary bicarbonate excretion. World J Gastroenterol (2006) 1.08
Bicarbonate-dependent and -independent intracellular pH regulatory mechanisms in rat hepatocytes. Evidence for Na+-HCO3- cotransport. J Clin Invest (1989) 1.05
Blockage of cell-to-cell communication within pancreatic acini is associated with increased basal release of amylase. J Cell Biol (1986) 1.05
Agonist-evoked changes in cytosolic pH and calcium concentration in human platelets: studies in physiological bicarbonate. J Physiol (1990) 1.04
Cytoplasmic [Ca2+] and intracellular pH in lymphocytes. Role of membrane potential and volume-activated Na+/H+ exchange. J Gen Physiol (1987) 1.04
Effects of temperature on calcium-sensitive fluorescent probes. Biophys J (2000) 1.04
The regulation of cytosolic pH in isolated presynaptic nerve terminals from rat brain. J Gen Physiol (1988) 1.03
Analysis of the relationship between the decrease in pH and accumulation of 3-phosphoglyceric acid in developing forespores of Bacillus species. J Bacteriol (1996) 1.02
Phosphorylation-dependent and -independent pathways of platelet aggregation. Biochem J (1989) 1.02
Transmembrane signaling by the B subunit of cholera toxin: increased cytoplasmic free calcium in rat lymphocytes. J Cell Biol (1987) 1.01
Evidence from renal proximal tubules that HCO3- and solute reabsorption are acutely regulated not by pH but by basolateral HCO3- and CO2. Proc Natl Acad Sci U S A (2005) 1.01
Fluorescence emission spectroscopy of 1,4-dihydroxyphthalonitrile. A method for determining intracellular pH in cultured cells. Biophys J (1985) 1.01
Diffusible magnesium in frog skeletal muscle cells. Biophys J (1983) 1.00
Basolateral membrane Cl/HCO3 exchange in the rat proximal convoluted tubule. Na-dependent and -independent modes. J Gen Physiol (1987) 0.99
Effects of ammonium on intracellular pH in rat medullary thick ascending limb: mechanisms of apical membrane NH4+ transport. J Gen Physiol (1994) 0.99
Activation of Na+/H+ exchange in human platelets stimulated by thrombin and a phorbol ester. Biochem J (1987) 0.99
A Chinese hamster ovary cell mutant defective in the non-endocytic uptake of fluorescent analogs of phosphatidylserine: isolation using a cytosol acidification protocol. J Cell Biol (1995) 0.98
Changes in free cytoplasmic magnesium following activation of human lymphocytes. Biochem J (1993) 0.98
Intracellular free magnesium in neurones of Helix aspersa measured with ion-selective micro-electrodes. J Physiol (1984) 0.98
Are there subtypes of the inositol 1,4,5-trisphosphate receptor? Biochem J (1990) 0.97
Selective cellular acidification and toxicity of weak organic acids in an acidic microenvironment. Br J Cancer (1993) 0.96
Apical membrane chloride/base exchange in the rat proximal convoluted tubule. J Clin Invest (1987) 0.94
Effects of pH conditions on Ca2+ transport catalyzed by ionophores A23187, 4-BrA23187, and ionomycin suggest problems with common applications of these compounds in biological systems. Biophys J (1995) 0.92
The central role of cAMP in regulating Plasmodium falciparum merozoite invasion of human erythrocytes. PLoS Pathog (2014) 0.92
Mechanism of osmotic activation of Na+/H+ exchange in rat thymic lymphocytes. J Gen Physiol (1985) 0.92
Membrane potential of mitochondria in intact lymphocytes during early mitogenic stimulation. Biochem J (1984) 0.92
Anion transport and GABA signaling. Front Cell Neurosci (2013) 0.91
Arachidonic acid-induced calcium influx in human platelets. Comparison with the effect of thrombin. Biochem J (1990) 0.91
A chemoreceptor that detects molecular carbon dioxide. J Biol Chem (2013) 0.91
Effects of lowering extracellular and cytosolic pH on calcium fluxes, cytosolic calcium levels, and transmitter release in presynaptic nerve terminals isolated from rat brain. J Gen Physiol (1988) 0.91
Mechanism of oxidative stress-induced intracellular acidosis in rat cerebellar astrocytes and C6 glioma cells. J Physiol (1997) 0.90
Inhibition of Giardia lamblia excystation by antibodies against cyst walls and by wheat germ agglutinin. Infect Immun (1996) 0.90
Interleukin-3-stimulated haemopoietic stem cell proliferation. Evidence for activation of protein kinase C and Na+/H+ exchange without inositol lipid hydrolysis. Biochem J (1988) 0.90
Changes in intra- or extracellular pH do not mediate P-glycoprotein-dependent multidrug resistance. Proc Natl Acad Sci U S A (1993) 0.89
Indirect evidence for the presence of non-specific anion channels in rabbit mandibular salivary gland acinar cells. J Physiol (1989) 0.89
The bivalent-cation dependence of phosphatidylinositol synthesis in a cell-free system from lymphocytes. Biochem J (1983) 0.89
Investigation of the relationship between altered intracellular pH and multidrug resistance in mammalian cells. Br J Cancer (1990) 0.89
Development and properties of genetically encoded pH sensors in plants. Front Plant Sci (2013) 0.89
Roles of calcium and pH in activation of eggs of the medaka fish, Oryzias latipes. J Cell Biol (1983) 0.89
Regulation of Cl/HCO3 exchange in gastric parietal cells. Cell Regul (1991) 0.88
Buffered diffusion around a spherical proton pumping cell: a theoretical analysis. Biophys J (2007) 0.88
The delayed basolateral membrane hyperpolarization of the bovine retinal pigment epithelium: mechanism of generation. J Physiol (1995) 0.88
Restitution at the cellular level: regulation of the migrating phenotype. Yale J Biol Med (1997) 0.87
Monitoring intracellular pH changes in response to osmotic stress and membrane transport activity using 5-chloromethylfluorescein. AAPS PharmSci (2002) 0.87
Influence of Mg2+ and pH on n.m.r. spectra and radioligand binding of inositol 1,4,5-trisphosphate. Biochem J (1991) 0.86
Intracellular pH. Physiol Rev (1981) 16.27
Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator. J Cell Biol (1982) 11.87
Intracellular pH measurements in Ehrlich ascites tumor cells utilizing spectroscopic probes generated in situ. Biochemistry (1979) 11.28
Membrane properties of living mammalian cells as studied by enzymatic hydrolysis of fluorogenic esters. Proc Natl Acad Sci U S A (1966) 8.92
Determination of intracellular pH by 31P magnetic resonance. J Biol Chem (1973) 6.71
A non-disruptive technique for loading calcium buffers and indicators into cells. Nature (1981) 5.72
Neutral carrier ion-selective microelectrodes for measurement of intracellular free calcium. Biochim Biophys Acta (1980) 5.34
Estimation of membrane potential and pH difference across the cristae membrane of rat liver mitochondria. Eur J Biochem (1969) 3.97
Lymphocyte membrane potential assessed with fluorescent probes. Biochim Biophys Acta (1980) 3.33
Hormonal effects on calcium homeostasis in isolated hepatocytes. J Biol Chem (1980) 3.08
The concentrations of free and bound magnesium in rat tissues. Relative constancy of free Mg 2+ concentrations. J Biol Chem (1973) 2.99
Free calcium ions in neurones of Helix aspersa measured with ion-selective micro-electrodes. J Physiol (1981) 2.75
Is an early calcium flux necessary to stimulate lymphocytes? Nature (1977) 2.03
31P NMR studies of intracellular free Mg2+ in intact frog skeletal muscle. J Biol Chem (1980) 2.01
Use of ionophore A23187 to measure and to control free and bound cytoplasmic Mg in intact red cells. Nature (1977) 1.53
Calcium and magnesium ions and the regulation of multiplication in normal and transformed cells. Nature (1978) 1.46
Early changes of 'leak flux' and the cation content of lymphocytes by concanavalin A. Biochem Biophys Res Commun (1976) 1.37
Effects of fructose on the energy metabolism and acid-base status of the perfused starved-rat liver. A 31phosphorus nuclear magnetic resonance study. Biochem J (1980) 1.32
Major intracellular cations and growth control: correspondence among magnesium content, protein synthesis, and the onset of DNA synthesis in BALB/c3T3 cells. Proc Natl Acad Sci U S A (1979) 1.19
Intracellular pH of the human lymphocyte. Am J Physiol (1967) 1.17
A new generation of Ca2+ indicators with greatly improved fluorescence properties. J Biol Chem (1985) 90.20
Fluorescent indicators for Ca2+ based on green fluorescent proteins and calmodulin. Nature (1997) 18.83
Crystal structure of the Aequorea victoria green fluorescent protein. Science (1996) 16.81
Improved green fluorescence. Nature (1995) 12.65
Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator. J Cell Biol (1982) 11.87
New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures. Biochemistry (1980) 11.70
Wavelength mutations and posttranslational autoxidation of green fluorescent protein. Proc Natl Acad Sci U S A (1994) 10.50
On/off blinking and switching behaviour of single molecules of green fluorescent protein. Nature (1997) 9.97
Identification of a signal for rapid export of proteins from the nucleus. Cell (1995) 9.92
Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses. Science (1998) 9.90
Engineering green fluorescent protein for improved brightness, longer wavelengths and fluorescence resonance energy transfer. Curr Biol (1996) 9.72
Specific covalent labeling of recombinant protein molecules inside live cells. Science (1998) 9.32
Reducing the environmental sensitivity of yellow fluorescent protein. Mechanism and applications. J Biol Chem (2001) 9.27
Biochemistry, mutagenesis, and oligomerization of DsRed, a red fluorescent protein from coral. Proc Natl Acad Sci U S A (2000) 7.68
Circular permutation and receptor insertion within green fluorescent proteins. Proc Natl Acad Sci U S A (1999) 7.55
Understanding, improving and using green fluorescent proteins. Trends Biochem Sci (1995) 7.51
Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophores. J Biol Chem (1989) 7.22
Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations. Science (2000) 6.98
Measurement of cytosolic, mitochondrial, and Golgi pH in single living cells with green fluorescent proteins. Proc Natl Acad Sci U S A (1998) 6.73
Dynamic and quantitative Ca2+ measurements using improved cameleons. Proc Natl Acad Sci U S A (1999) 6.63
Microdomains with high Ca2+ close to IP3-sensitive channels that are sensed by neighboring mitochondria. Science (1993) 6.29
Calcium channels, stores, and oscillations. Annu Rev Cell Biol (1990) 6.12
The structure of the chromophore within DsRed, a red fluorescent protein from coral. Proc Natl Acad Sci U S A (2000) 5.88
A non-disruptive technique for loading calcium buffers and indicators into cells. Nature (1981) 5.72
Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx. Nature (1993) 5.55
Neutral carrier ion-selective microelectrodes for measurement of intracellular free calcium. Biochim Biophys Acta (1980) 5.34
Rapid changes of mitochondrial Ca2+ revealed by specifically targeted recombinant aequorin. Nature (1992) 5.17
Structural basis for dual excitation and photoisomerization of the Aequorea victoria green fluorescent protein. Proc Natl Acad Sci U S A (1997) 4.99
Cell-permeant caged InsP3 ester shows that Ca2+ spike frequency can optimize gene expression. Nature (1998) 4.93
Monitoring protein conformations and interactions by fluorescence resonance energy transfer between mutants of green fluorescent protein. Methods Enzymol (2000) 4.87
T-cell mitogens cause early changes in cytoplasmic free Ca2+ and membrane potential in lymphocytes. Nature (1982) 4.83
Fluorescence ratio imaging of cyclic AMP in single cells. Nature (1991) 4.45
Diacylglycerol and phorbol ester stimulate secretion without raising cytoplasmic free calcium in human platelets. Nature (1983) 4.34
Measurement of cytosolic free Ca2+ with quin2. Methods Enzymol (1989) 4.33
Calcium gradients in single smooth muscle cells revealed by the digital imaging microscope using Fura-2. Nature (1986) 4.21
Quantitation of transcription and clonal selection of single living cells with beta-lactamase as reporter. Science (1998) 4.15
Prostaglandins stimulate calcium-dependent glutamate release in astrocytes. Nature (1998) 4.03
Is cytosolic ionized calcium regulating neutrophil activation? Science (1983) 3.97
SK&F 96365, a novel inhibitor of receptor-mediated calcium entry. Biochem J (1990) 3.86
The Ca2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action. EMBO J (2001) 3.85
Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering. Proc Natl Acad Sci U S A (2001) 3.77
Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor. Nature (1987) 3.75
Receptor-activated Ca2+ influx: how many mechanisms for how many channels? Trends Pharmacol Sci (1994) 3.63
Repetitive spikes in cytoplasmic calcium evoked by histamine in human endothelial cells. Nature (1988) 3.57
Changes of free calcium levels with stages of the cell division cycle. Nature (1985) 3.48
Na+/H+ exchange and cytoplasmic pH in the action of growth factors in human fibroblasts. Nature (1983) 3.47
Optical imaging of calcium transients in neurons and pharyngeal muscle of C. elegans. Neuron (2000) 3.44
Photochemically generated cytosolic calcium pulses and their detection by fluo-3. J Biol Chem (1989) 3.44
Chimeric green fluorescent protein as a tool for visualizing subcellular organelles in living cells. Curr Biol (1995) 3.44
Single stretch-activated ion channels in vascular endothelial cells as mechanotransducers? Nature (1987) 3.37
Reduced loading of intracellular Ca(2+) stores and downregulation of capacitative Ca(2+) influx in Bcl-2-overexpressing cells. J Cell Biol (2000) 3.35
Lymphocyte membrane potential assessed with fluorescent probes. Biochim Biophys Acta (1980) 3.33
Cytosolic Ca2+ homeostasis in Ehrlich and Yoshida carcinomas. A new, membrane-permeant chelator of heavy metals reveals that these ascites tumor cell lines have normal cytosolic free Ca2+. J Biol Chem (1985) 3.31
Measurement of cytosolic free Ca2+ in individual small cells using fluorescence microscopy with dual excitation wavelengths. Cell Calcium (1985) 3.23
Changes in intramitochondrial and cytosolic pH: early events that modulate caspase activation during apoptosis. Nat Cell Biol (2000) 3.20
Intracellular calcium oscillations in astrocytes: a highly plastic, bidirectional form of communication between neurons and astrocytes in situ. J Neurosci (1997) 3.18
Molecular spectroscopy and dynamics of intrinsically fluorescent proteins: coral red (dsRed) and yellow (Citrine). Proc Natl Acad Sci U S A (2000) 3.07
Fluorescence and bioluminescence measurement of cytoplasmic free calcium. Biochem J (1987) 3.00
"Calciosome," a cytoplasmic organelle: the inositol 1,4,5-trisphosphate-sensitive Ca2+ store of nonmuscle cells? Proc Natl Acad Sci U S A (1988) 2.99
Controlling cell chemistry with caged compounds. Annu Rev Physiol (1993) 2.99
Transfected aequorin in the measurement of cytosolic Ca2+ concentration ([Ca2+]c). A critical evaluation. J Biol Chem (1995) 2.91
Fluorescent indicators for cytosolic sodium. J Biol Chem (1989) 2.89
Alteration of stimulus-specific guard cell calcium oscillations and stomatal closing in Arabidopsis det3 mutant. Science (2000) 2.80
Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells. Proc Natl Acad Sci U S A (2001) 2.77
Free calcium ions in neurones of Helix aspersa measured with ion-selective micro-electrodes. J Physiol (1981) 2.75
Receptor-mediated calcium entry in fura-2-loaded human platelets stimulated with ADP and thrombin. Dual-wavelengths studies with Mn2+. Biochem J (1989) 2.73
Agonists stimulate divalent cation channels in the plasma membrane of human platelets. FEBS Lett (1985) 2.72
Inositol 1,4,5-trisphosphate: a possible chemical link in excitation-contraction coupling in muscle. Proc Natl Acad Sci U S A (1985) 2.68
Anti-immunoglobulin, cytoplasmic free calcium, and capping in B lymphocytes. J Cell Biol (1982) 2.67
Cytoplasmic free Ca2+ in human platelets: Ca2+ thresholds and Ca-independent activation for shape-change and secretion. FEBS Lett (1982) 2.60
Fura-2 measurement of cytosolic free Ca2+ in monolayers and suspensions of various types of animal cells. J Cell Biol (1987) 2.57
Imaging of cytosolic Ca2+ transients arising from Ca2+ stores and Ca2+ channels in sympathetic neurons. Neuron (1988) 2.56
Free calcium in heart muscle at rest and during contraction measured with Ca2+ -sensitive microelectrodes. Nature (1980) 2.55
Activation of a muscarinic receptor selectively inhibits a rapidly inactivated Ca2+ current in rat sympathetic neurons. Proc Natl Acad Sci U S A (1987) 2.54
Spatially resolved dynamics of cAMP and protein kinase A subunits in Aplysia sensory neurons. Science (1993) 2.51
Liberation of [3H]arachidonic acid and changes in cytosolic free calcium in fura-2-loaded human platelets stimulated by ionomycin and collagen. Biochem J (1986) 2.50
Protein kinase C activation of physiological processes in human neutrophils at vanishingly small cytosolic Ca2+ levels. Nature (1984) 2.49
Fluorescence photooxidation with eosin: a method for high resolution immunolocalization and in situ hybridization detection for light and electron microscopy. J Cell Biol (1994) 2.48
Mitochondria as all-round players of the calcium game. J Physiol (2000) 2.47
Generation of calcium oscillations in fibroblasts by positive feedback between calcium and IP3. Science (1991) 2.45
The endoplasmic reticulum Ca2+ store: a view from the lumen. Trends Biochem Sci (1998) 2.37
A genetically encoded, fluorescent indicator for cyclic AMP in living cells. Nat Cell Biol (2000) 2.34
Brominated 7-hydroxycoumarin-4-ylmethyls: photolabile protecting groups with biologically useful cross-sections for two photon photolysis. Proc Natl Acad Sci U S A (1999) 2.33
Subcellular imaging of intramitochondrial Ca2+ with recombinant targeted aequorin: significance for the regulation of pyruvate dehydrogenase activity. Proc Natl Acad Sci U S A (1996) 2.33
Mitochondrial Ca2+ homeostasis in intact cells. J Cell Biol (1994) 2.28