Published in Nature on July 09, 1987
Suppression in Drosophila: su(Hw) and su(f) gene products interact with a region of gypsy (mdg4) regulating its transcriptional activity. EMBO J (1989) 2.16
DNA supercoiling changes the spacing requirement of two lac operators for DNA loop formation with lac repressor. EMBO J (1988) 1.70
Regulation of mouse CYP1A1 gene expression by dioxin: requirement of two cis-acting elements during induction. Mol Cell Biol (1989) 1.49
The DNA target of the trp repressor. EMBO J (1992) 0.96
Synergistic action of glucocorticoid and estradiol responsive elements. Proc Natl Acad Sci U S A (1988) 0.89
Identification and characterization of the familial adenomatous polyposis coli gene. Cell (1991) 14.46
A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations. Cell (1990) 8.10
Sequence of chicken ovalbumin mRNA. Nature (1978) 6.73
Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis. JAMA (2005) 5.60
Identification of deletion mutations and three new genes at the familial polyposis locus. Cell (1991) 5.42
The neurofibromatosis type 1 gene encodes a protein related to GAP. Cell (1990) 5.24
Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression. Proc Natl Acad Sci U S A (1994) 4.44
The prevalence of homelessness among adolescents in the United States. Am J Public Health (1998) 4.07
Alleles of the APC gene: an attenuated form of familial polyposis. Cell (1993) 3.84
The Emerging Risk Factors Collaboration: analysis of individual data on lipid, inflammatory and other markers in over 1.1 million participants in 104 prospective studies of cardiovascular diseases. Eur J Epidemiol (2007) 3.81
Another advanced test of theory of mind: evidence from very high functioning adults with autism or asperger syndrome. J Child Psychol Psychiatry (1997) 3.68
Somatic mutations in the neurofibromatosis 1 gene in human tumors. Cell (1992) 3.20
Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells. EMBO J (1995) 3.16
Relationship of Ki-ras mutations in colon cancers to tumor location, stage, and survival: a population-based study. Cancer Epidemiol Biomarkers Prev (2000) 3.05
Blood-lead and hypertension. Lancet (1976) 2.82
Identification of a mutation in the gene causing hyperkalemic periodic paralysis. Cell (1991) 2.48
The RNA-binding protein TIAR is translocated from the nucleus to the cytoplasm during Fas-mediated apoptotic cell death. Proc Natl Acad Sci U S A (1995) 2.15
Genomic organization of the neurofibromatosis 1 gene (NF1). Genomics (1995) 1.79
U1 small nuclear RNA genes are located on human chromosome 1 and are expressed in mouse-human hybrid cells. Mol Cell Biol (1983) 1.76
Mutations in an S4 segment of the adult skeletal muscle sodium channel cause paramyotonia congenita. Neuron (1992) 1.75
Fas-activated serine/threonine kinase (FAST) phosphorylates TIA-1 during Fas-mediated apoptosis. J Exp Med (1995) 1.75
Mutational analysis of patients with adenomatous polyposis: identical inactivating mutations in unrelated individuals. Am J Hum Genet (1993) 1.72
A clinical study of Gilles de la Tourette syndrome in the United Kingdom. J Neurol Neurosurg Psychiatry (1984) 1.72
Alleles of APC modulate the frequency and classes of mutations that lead to colon polyps. Nat Genet (1998) 1.71
Agreement between arterial and central venous values for pH, bicarbonate, base excess, and lactate. Emerg Med J (2006) 1.68
False start on manic depression. Nature (1989) 1.64
High resolution computed tomographic assessment of airway wall thickness in chronic asthma: reproducibility and relationship with lung function and severity. Thorax (2002) 1.57
Clinical profiles and outcomes in patients with chronic heart failure and chronic obstructive pulmonary disease: an efficacy and safety analysis of SHIFT study. Int J Cardiol (2013) 1.55
Factor VIII von Willebrand protein in haemolytic uraemic syndrome and systemic vasculitides. Lancet (1990) 1.46
Peripheral myelin protein-22 gene maps in the duplication in chromosome 17p11.2 associated with Charcot-Marie-Tooth 1A. Nat Genet (1992) 1.43
Complete heart block and sudden death in mice overexpressing calreticulin. J Clin Invest (2001) 1.43
Possible linkage of Tourette syndrome to markers on short arm of chromosome 3 (C3p21-14) Lancet (1990) 1.42
Sodium channel mutations in paramyotonia congenita and hyperkalemic periodic paralysis. Ann Neurol (1993) 1.41
'Topping up' methadone: an analysis of patterns of heroin use among a treatment sample of Scottish drug users. Public Health (2008) 1.39
An Ad5-vectored HIV-1 vaccine elicits cell-mediated immunity but does not affect disease progression in HIV-1-infected male subjects: results from a randomized placebo-controlled trial (the Step study). J Infect Dis (2011) 1.37
Interleukin-6 inhibits Fas-induced apoptosis and stress-activated protein kinase activation in multiple myeloma cells. Blood (1997) 1.37
Response of colon cancer cell lines to the introduction of APC, a colon-specific tumor suppressor gene. Cancer Res (1995) 1.37
The external transcribed spacer and preceding region of Xenopus borealis rDNA: comparison with the corresponding region of Xenopus laevis rDNA. Nucleic Acids Res (1983) 1.34
Circles: the replication-recombination-chromosome segregation connection. Proc Natl Acad Sci U S A (2001) 1.34
EYA4, a novel vertebrate gene related to Drosophila eyes absent. Hum Mol Genet (1999) 1.32
A survey of nucleic acid services in core laboratories. Biotechniques (1994) 1.31
The Arabidopsis protein SHI represses gibberellin responses in Arabidopsis and barley. Plant Physiol (2001) 1.30
Direct detection and automated sequencing of individual alleles after electrophoretic strand separation: identification of a common nonsense mutation in exon 9 of the human lipoprotein lipase gene. Nucleic Acids Res (1990) 1.29
The prevalence of psychotic symptoms in homeless adolescents. J Am Acad Child Adolesc Psychiatry (1990) 1.29
Rapidly swept, ultra-widely-tunable 1060 nm MEMS-VCSELs. Electron Lett (2012) 1.28
Systematically missing confounders in individual participant data meta-analysis of observational cohort studies. Stat Med (2009) 1.27
Quality of life and oral function in patients treated with radiation therapy for head and neck cancer. Head Neck (2001) 1.27
A gene for distal arthrogryposis type I maps to the pericentromeric region of chromosome 9. Am J Hum Genet (1994) 1.24
Outreach and screening following the 2005 London bombings: usage and outcomes. Psychol Med (2010) 1.20
The prevalence of Tourette syndrome in 13-14-year-olds in mainstream schools. J Child Psychol Psychiatry (2001) 1.19
Multi-facility survey of oligonucleotide synthesis and an examination of the performance of unpurified primers in automated DNA sequencing. Biotechniques (1996) 1.19
Differentiation inhibiting activity (DIA/LIF) and mouse development. Dev Biol (1992) 1.18
Identification of APC gene mutations in Italian adenomatous polyposis coli patients by PCR-SSCP analysis. Am J Hum Genet (1993) 1.16
Phosphorylase b kinase inheritance in mice. Science (1967) 1.14
Macroaggregate formation in optimal additive red cells. Vox Sang (1985) 1.13
Acute lower gastrointestinal bleeding as a late complication of spinal instrumentation. J Pediatr Surg (2001) 1.13
Actions and comparative efficacy of phosphatidylcholine formulation and isolated sodium deoxycholate for different cell types. Aesthetic Plast Surg (2009) 1.13
Genetic mapping of the BRCA1 region on chromosome 17q21. Am J Hum Genet (1994) 1.13
Human cytomegalovirus a sequence and UL144 variability in strains from infected children. J Med Virol (2001) 1.12
Interaction of DNA-binding proteins with a milk protein gene promoter in vitro: identification of a mammary gland-specific factor. Nucleic Acids Res (1991) 1.11
Homoeo boxes, POU proteins and the limits to promiscuity. Nature (1988) 1.11
Effect of heart rate reduction by ivabradine on left ventricular remodeling in the echocardiographic substudy of BEAUTIFUL. Int J Cardiol (2010) 1.11
Recommendations for toxicological investigations of drug-facilitated sexual assaults. J Forensic Sci (1999) 1.09
Clinical features and associated psychopathology in a Tourette syndrome cohort. Acta Neurol Scand (2004) 1.08
High-sweep-rate 1310 nm MEMS-VCSEL with 150 nm continuous tuning range. Electron Lett (2012) 1.08
Retinoic acid receptor. Towards a biochemistry of morphogenesis. Nature (1988) 1.06
Polymorphic SSR (simple-sequence-repeat) markers for chromosome 20. Genomics (1993) 1.04
CD6-depleted allogeneic bone marrow transplantation for acute leukemia in first complete remission. Blood (1997) 1.04
Factors associated with the wish to hasten death: a study of patients with terminal illness. Psychol Med (2003) 1.03
Detection of hepatitis B surface antigen among Scottish blood donors: evaluation of sensitive tanned-cell haemagglutination-inhibition test. Br Med J (1975) 1.03
The effect of gamma-ray irradiation upon the growth and nitrogenous metabolism of the protozoon, Bodo caudatus. Biochem J (1935) 1.02
Plasma C reactive protein concentration indicates a direct relation between systemic inflammation and social deprivation. Heart (2006) 1.01
The identical 5' splice-site acceptor mutation in five attenuated APC families from Newfoundland demonstrates a founder effect. Hum Genet (1999) 1.01
Nucleotide sequence of a wheat (Triticum aestivum L.) cDNA clone encoding the waxy protein. Plant Mol Biol (1991) 1.01
The proper study of mankind. Nature (1986) 1.01
Novel P2X7 receptor antagonists. Bioorg Med Chem Lett (2003) 1.00
Terminally ill cancer patients' wish to hasten death. Palliat Med (2002) 0.99
Accuracy of automated DNA sequencing: a multi-laboratory comparison of sequencing results. Biotechniques (1995) 0.99
Group interpersonal psychotherapy for postnatal depression: a pilot study. Arch Womens Ment Health (2005) 0.98
Lipoprotein lipase deficiency resulting from a nonsense mutation in exon 3 of the lipoprotein lipase gene. Am J Hum Genet (1990) 0.97
Antigen processing. Proteasomes in the pathway. Nature (1991) 0.97
Paracrine induction of stem cell renewal by LIF-deficient cells: a new ES cell regulatory pathway. Dev Biol (1998) 0.96
Predictors of progression in long-term nonprogressors. Australian Long-Term Nonprogressor Study Group. AIDS Res Hum Retroviruses (1998) 0.94
Paradox and paradigm: the message and meaning of myc. Nature (1984) 0.94
Improved outcomes in paediatric intestinal failure with aggressive prevention of liver disease. Eur J Pediatr Surg (2009) 0.94
Muscular dystrophy: mapping the disease phenotype. Nature (1987) 0.93
Onset and duration of protective immunity to IA/IB and IE strains of Venezuelan equine encephalitis virus in vaccinated mice. Vaccine (2001) 0.93
Bayesian methods for meta-analysis of causal relationships estimated using genetic instrumental variables. Stat Med (2010) 0.93
Providing guidelines and education is not enough: an audit of gentamicin use at The Royal Melbourne Hospital. Intern Med J (2006) 0.92
The humoral antibacterial response of Drosophila adults. Dev Comp Immunol (1986) 0.91
Role of JNK in hypertonic activation of Cl(-)-dependent Na(+)/H(+) exchange in Xenopus oocytes. Am J Physiol Cell Physiol (2001) 0.90
Structure of the mouse leukaemia inhibitory factor receptor gene: regulated expression of mRNA encoding a soluble receptor isoform from an alternative 5' untranslated region. Biochem J (1997) 0.90
Regulation of glucose transporter (GLUT 3) and aldose reductase mRNA inbovine retinal endothelial cells and retinal pericytes in high glucose and high galactose culture. Diabetologia (1993) 0.90
Noise levels in infant oxygen tents. Lancet (1970) 0.89
Message of myc in context. Nature (1984) 0.88
The evolutionary past of the major histocompatibility complex and the future of cellular immunology. Nature (1982) 0.88
Virological and immunological effects of combination antiretroviral therapy with zidovudine, lamivudine, and indinavir during primary human immunodeficiency virus type 1 infection. J Infect Dis (2000) 0.88
Isolated central nervous system lymphoid blast crisis in chronic myeloid leukaemia in major molecular remission. Br J Haematol (2008) 0.88
Abnormalities of copper in Gilles de la Tourette syndrome. Biol Psychiatry (1987) 0.86