Published in Am J Hum Genet on February 01, 1993
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Exclusion of constitutional p53 mutations as a cause of genetic susceptibility to colorectal cancer. Br J Cancer (1993) 0.77
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Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers. Science (1991) 6.15
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The gene for familial polyposis coli maps to the long arm of chromosome 5. Science (1987) 4.48
Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients. Proc Natl Acad Sci U S A (1992) 4.13
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A CA repeat 30-70 KB downstream from the adenomatous polyposis coli (APC) gene. Nucleic Acids Res (1991) 1.69
Eight novel inactivating germ line mutations at the APC gene identified by denaturing gradient gel electrophoresis. Genomics (1992) 1.59
Germ-line mutations in the first 14 exons of the adenomatous polyposis coli (APC) gene. Am J Hum Genet (1993) 1.53
Identification of APC gene mutations in Italian adenomatous polyposis coli patients by PCR-SSCP analysis. Am J Hum Genet (1993) 1.16
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Identification and characterization of the familial adenomatous polyposis coli gene. Cell (1991) 14.46
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A yeast gene that is essential for release from glucose repression encodes a protein kinase. Science (1986) 7.73
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Genes affecting the regulation of SUC2 gene expression by glucose repression in Saccharomyces cerevisiae. Genetics (1984) 6.09
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Identification of deletion mutations and three new genes at the familial polyposis locus. Cell (1991) 5.42
The neurofibromatosis type 1 gene encodes a protein related to GAP. Cell (1990) 5.24
The gene for familial polyposis coli maps to the long arm of chromosome 5. Science (1987) 4.48
Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression. Proc Natl Acad Sci U S A (1994) 4.44
The prevalence of homelessness among adolescents in the United States. Am J Public Health (1998) 4.07
Repression by SSN6-TUP1 is directed by MIG1, a repressor/activator protein. Proc Natl Acad Sci U S A (1995) 4.06
The secreted form of invertase in Saccharomyces cerevisiae is synthesized from mRNA encoding a signal sequence. Mol Cell Biol (1983) 3.96
Alleles of the APC gene: an attenuated form of familial polyposis. Cell (1993) 3.84
Cloning and genetic mapping of SNF1, a gene required for expression of glucose-repressible genes in Saccharomyces cerevisiae. Mol Cell Biol (1984) 3.81
The Emerging Risk Factors Collaboration: analysis of individual data on lipid, inflammatory and other markers in over 1.1 million participants in 104 prospective studies of cardiovascular diseases. Eur J Epidemiol (2007) 3.81
A suppressor of SNF1 mutations causes constitutive high-level invertase synthesis in yeast. Genetics (1984) 3.81
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Localization of the genetic defect in familial adenomatous polyposis within a small region of chromosome 5. Am J Hum Genet (1988) 3.58
Molecular analysis of SSN6, a gene functionally related to the SNF1 protein kinase of Saccharomyces cerevisiae. Mol Cell Biol (1987) 3.57
Functional interdependence of the yeast SNF2, SNF5, and SNF6 proteins in transcriptional activation. Proc Natl Acad Sci U S A (1991) 3.55
The yeast SNF2/SWI2 protein has DNA-stimulated ATPase activity required for transcriptional activation. Genes Dev (1993) 3.50
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A protein kinase substrate identified by the two-hybrid system. Science (1992) 3.34
Gene expression profile of antithrombotic protein c defines new mechanisms modulating inflammation and apoptosis. J Biol Chem (2001) 3.31
Somatic mutations in the neurofibromatosis 1 gene in human tumors. Cell (1992) 3.20
Yeast SNF1 is functionally related to mammalian AMP-activated protein kinase and regulates acetyl-CoA carboxylase in vivo. J Biol Chem (1994) 3.18
Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells. EMBO J (1995) 3.16
Molecular analysis of the SNF4 gene of Saccharomyces cerevisiae: evidence for physical association of the SNF4 protein with the SNF1 protein kinase. Mol Cell Biol (1989) 3.13
Upstream region required for regulated expression of the glucose-repressible SUC2 gene of Saccharomyces cerevisiae. Mol Cell Biol (1984) 3.06
Mutational analysis of the Saccharomyces cerevisiae SNF1 protein kinase and evidence for functional interaction with the SNF4 protein. Mol Cell Biol (1989) 3.06
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Two homologous zinc finger genes identified by multicopy suppression in a SNF1 protein kinase mutant of Saccharomyces cerevisiae. Mol Cell Biol (1993) 3.00
The yeast SNF3 gene encodes a glucose transporter homologous to the mammalian protein. Proc Natl Acad Sci U S A (1988) 2.99
Glucose regulates protein interactions within the yeast SNF1 protein kinase complex. Genes Dev (1996) 2.97
Gastric adenocarcinoma and dysplasia in fundic gland polyps of a patient with attenuated adenomatous polyposis coli. Gastroenterology (1997) 2.96
Evolution of the dispersed SUC gene family of Saccharomyces by rearrangements of chromosome telomeres. Mol Cell Biol (1985) 2.88
The SNF5 protein of Saccharomyces cerevisiae is a glutamine- and proline-rich transcriptional activator that affects expression of a broad spectrum of genes. Mol Cell Biol (1990) 2.87
Nucleotide sequence of the yeast SUC2 gene for invertase. Nucleic Acids Res (1983) 2.86
Iron overload in Africa. Interaction between a gene and dietary iron content. N Engl J Med (1992) 2.85
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An essential Saccharomyces cerevisiae gene homologous to SNF2 encodes a helicase-related protein in a new family. Mol Cell Biol (1992) 2.78
The SNF3 gene is required for high-affinity glucose transport in Saccharomyces cerevisiae. J Bacteriol (1987) 2.77
A randomized trial of bromocriptine for cocaine users presenting to the emergency department. J Gen Intern Med (1993) 2.71
Snf1 protein kinase regulates phosphorylation of the Mig1 repressor in Saccharomyces cerevisiae. Mol Cell Biol (1998) 2.69
Structure and expression of the SNF1 gene of Saccharomyces cerevisiae. Mol Cell Biol (1984) 2.69
A family of proteins containing a conserved domain that mediates interaction with the yeast SNF1 protein kinase complex. EMBO J (1994) 2.66
Mutations causing constitutive invertase synthesis in yeast: genetic interactions with snf mutations. Genetics (1987) 2.65
Linkage disequilibrium predicts physical distance in the adenomatous polyposis coli region. Am J Hum Genet (1994) 2.65
Suppressors of SNF2 mutations restore invertase derepression and cause temperature-sensitive lethality in yeast. Genetics (1986) 2.64
Upstream region of the SUC2 gene confers regulated expression to a heterologous gene in Saccharomyces cerevisiae. Mol Cell Biol (1985) 2.52
REG1 binds to protein phosphatase type 1 and regulates glucose repression in Saccharomyces cerevisiae. EMBO J (1995) 2.50
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Identification of a mutation in the gene causing hyperkalemic periodic paralysis. Cell (1991) 2.48
Cyclin-dependent protein kinase and cyclin homologs SSN3 and SSN8 contribute to transcriptional control in yeast. Proc Natl Acad Sci U S A (1995) 2.48
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Subcellular localization of the Snf1 kinase is regulated by specific beta subunits and a novel glucose signaling mechanism. Genes Dev (2001) 2.45
The Snf1 protein kinase and its activating subunit, Snf4, interact with distinct domains of the Sip1/Sip2/Gal83 component in the kinase complex. Mol Cell Biol (1997) 2.42
Yeast SNF2/SWI2, SNF5, and SNF6 proteins function coordinately with the gene-specific transcriptional activators GAL4 and Bicoid. Genes Dev (1992) 2.38
Genetic analysis of an inherited predisposition to colon cancer in a family with a variable number of adenomatous polyps. N Engl J Med (1990) 2.32
Null mutations in the SNF3 gene of Saccharomyces cerevisiae cause a different phenotype than do previously isolated missense mutations. Mol Cell Biol (1986) 2.30
TUP1 utilizes histone H3/H2B-specific HDA1 deacetylase to repress gene activity in yeast. Mol Cell (2001) 2.29
Glucose-regulated interaction of a regulatory subunit of protein phosphatase 1 with the Snf1 protein kinase in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1998) 2.29
Genomewide search for type 2 diabetes susceptibility genes in four American populations. Am J Hum Genet (2000) 2.19
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The RNA-binding protein TIAR is translocated from the nucleus to the cytoplasm during Fas-mediated apoptotic cell death. Proc Natl Acad Sci U S A (1995) 2.15
Cloning of human and bovine homologs of SNF2/SWI2: a global activator of transcription in yeast S. cerevisiae. Nucleic Acids Res (1992) 2.14
Regulatory interactions between the Reg1-Glc7 protein phosphatase and the Snf1 protein kinase. Mol Cell Biol (2000) 2.09
Molecular analysis of SNF2 and SNF5, genes required for expression of glucose-repressible genes in Saccharomyces cerevisiae. Mol Cell Biol (1986) 2.07
Infliximab as rescue therapy in hospitalised patients with steroid-refractory acute ulcerative colitis: a long-term follow-up of 211 Swedish patients. Aliment Pharmacol Ther (2013) 2.05
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