The structure of human complement component C7 and the C5b-7 complex.

PubWeight™: 1.49‹?› | Rank: Top 4%

🔗 View Article (PMID 3335508)

Published in J Biol Chem on January 05, 1988

Authors

R G DiScipio1, D N Chakravarti, H J Muller-Eberhard, G H Fey

Author Affiliations

1: Department of Immunology, Research Institute of Scripps Clinic, La Jolla, California 92037.

Articles citing this

Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor. EMBO J (1988) 4.54

Human protectin (CD59), an 18,000-20,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayers. Immunology (1990) 2.77

Molecular cloning and characterization of the novel, human complement-associated protein, SP-40,40: a link between the complement and reproductive systems. EMBO J (1989) 1.52

Cloning, analysis, and expression of murine perforin 1 cDNA, a component of cytolytic T-cell granules with homology to complement component C9. Proc Natl Acad Sci U S A (1989) 1.50

Membrane attack by complement: the assembly and biology of terminal complement complexes. Immunol Res (2011) 1.28

Characterization of a cDNA encoding a cysteine-rich cell surface protein located in the flagellar pocket of the protozoan Trypanosoma brucei. Mol Cell Biol (1990) 1.10

Genomic organization of the mouse pore-forming protein (perforin) gene and localization to chromosome 10. Similarities to and differences from C9. J Exp Med (1990) 1.05

Structure of complement C6 suggests a mechanism for initiation and unidirectional, sequential assembly of membrane attack complex (MAC). J Biol Chem (2012) 1.04

A case of hereditary combined deficiency of complement components C6 and C7 in man. Clin Exp Immunol (1989) 0.97

Complement component C7 deficiency in a Spanish family. Clin Exp Immunol (2003) 0.90

Blood dendritic cells carry terminal complement complexes on their cell surface as detected by newly developed neoepitope-specific monoclonal antibodies. Immunology (1991) 0.88

The interaction between complement component C4b-binding protein and the vitamin K-dependent protein S forms a link between blood coagulation and the complement system. Biochem J (1991) 0.86

Structural homology of complement protein C6 with other channel-forming proteins of complement. Proc Natl Acad Sci U S A (1989) 0.83

Complement component C7 deficiency in two Spanish families. Immunology (2004) 0.81

Interaction between complement proteins C5b-7 and erythrocyte membrane sialic acid. J Exp Med (1996) 0.81

Solution structure of factor I-like modules from complement C7 reveals a pair of follistatin domains in compact pseudosymmetric arrangement. J Biol Chem (2009) 0.81

TaqI polymorphism in the complement component C7 gene. Nucleic Acids Res (1990) 0.81

Importance of the third thrombospondin repeat of C6 for terminal complement complex assembly. Immunology (1995) 0.80

Gene duplication of the seventh component of complement in rainbow trout. Immunogenetics (2005) 0.79

Two novel mutations in the C7 gene in a Korean patient with complement C7 deficiency. J Korean Med Sci (2005) 0.79

Complement components 2 and 7 (C2 and C7) gene polymorphisms are not major risk factors for SLE susceptibility in the Malaysian population. Rheumatol Int (2011) 0.76

Molecular defects of the C7 gene in two patients with complement C7 deficiency. Immunology (2006) 0.75

Articles by these authors

(truncated to the top 100)

Further studies on the chemotactic factor of complement and its formation in vivo. Immunology (1966) 7.59

A molecular concept of immune cytolysis. Arch Pathol (1966) 3.90

Human complement component C3: cDNA coding sequence and derived primary structure. Proc Natl Acad Sci U S A (1985) 3.37

The membrane attack mechanism of complement. Isolation and subunit composition of the C5b-9 complex. J Exp Med (1975) 2.32

Nucleotide sequence of cDNA and derived amino acid sequence of human complement component C9. Proc Natl Acad Sci U S A (1984) 2.01

Acute-phase reaction induces a specific complex between hepatic nuclear proteins and the interleukin 6 response element of the rat alpha 2-macroglobulin gene. Proc Natl Acad Sci U S A (1990) 1.66

Structure of the rat interleukin 6 gene and its expression in macrophage-derived cells. J Biol Chem (1989) 1.60

Localization of cloned unique DNA to three different regions of chromosome 19: screen for linkage probes for myotonic dystrophy. J Neurogenet (1985) 1.48

Synergistic action of interleukin-6 and glucocorticoids is mediated by the interleukin-6 response element of the rat alpha 2 macroglobulin gene. Mol Cell Biol (1992) 1.46

A 58-base-pair region of the human C3 gene confers synergistic inducibility by interleukin-1 and interleukin-6. Mol Cell Biol (1990) 1.39

Fine structure of translocation breakpoints in leukemic blasts with chromosomal translocation t(4;11): the DNA damage-repair model of translocation. Oncogene (1998) 1.39

A DNA damage repair mechanism is involved in the origin of chromosomal translocations t(4;11) in primary leukemic cells. Oncogene (1999) 1.39

Sequence of rat liver alpha 2-macroglobulin and acute phase control of its messenger RNA. J Biol Chem (1987) 1.38

Rab11b is essential for recycling of transferrin to the plasma membrane. Exp Cell Res (2000) 1.37

Isolation and characterization of two proteins from Moraxella catarrhalis that bear a common epitope. Infect Immun (1998) 1.32

Tight linkage of apolipoprotein C2 to myotonic dystrophy on chromosome 19. Neurology (1986) 1.31

Nucleotide sequence of complementary DNA and derived amino acid sequence of murine complement protein C3. Philos Trans R Soc Lond B Biol Sci (1984) 1.29

Transcription factors Stat3 and Stat5b are present in rat liver nuclei late in an acute phase response and bind interleukin-6 response elements. J Biol Chem (1995) 1.29

The acute lymphoblastic leukaemia cell line SEM with t(4;11) chromosomal rearrangement is biphenotypic and responsive to interleukin-7. Br J Haematol (1994) 1.24

The acute phase response of the liver in inflammation. Prog Liver Dis (1990) 1.22

The alpha-macroglobulin bait region. Sequence diversity and localization of cleavage sites for proteinases in five mammalian alpha-macroglobulins. J Biol Chem (1989) 1.20

Modified nuclear processing of alpha 1-acid glycoprotein RNA during inflammation. J Biol Chem (1987) 1.09

The leukemogenic fusion of MLL with ENL creates a novel transcriptional transactivator. Leukemia (1999) 1.09

IL-6 functions as an exocrine hormone in inflammation. Hepatocytes undergoing acute phase responses require exogenous IL-6. J Immunol (1990) 1.09

The C5b-9 complex: subunit composition of the classical and alternative pathway-generated complex. J Immunol (1976) 1.09

Exon/intron structure of the human AF-4 gene, a member of the AF-4/LAF-4/FMR-2 gene family coding for a nuclear protein with structural alterations in acute leukaemia. Br J Haematol (1997) 1.08

Receptors for interleukin (IL)-10 and IL-6-type cytokines use similar signaling mechanisms for inducing transcription through IL-6 response elements. J Biol Chem (1996) 1.07

Structure and acute-phase regulation of the rat alpha 2-macroglobulin gene. Biochemistry (1988) 1.07

Sequence and acute phase regulation of rat alpha 1-inhibitor III messenger RNA. J Biol Chem (1988) 1.06

Biased distribution of chromosomal breakpoints involving the MLL gene in infants versus children and adults with t(4;11) ALL. Oncogene (2001) 1.04

Separate signaling mechanisms are involved in the control of STAT protein activation and gene regulation via the interleukin 6 response element by the box 3 motif of gp130. J Biol Chem (1995) 1.03

STAT3 and STAT5B are targets of two different signal pathways activated by hematopoietin receptors and control transcription via separate cytokine response elements. J Biol Chem (1995) 1.02

Structure of murine complement component C3. I. Nucleotide sequence of cloned complementary and genomic DNA coding for the beta chain. J Biol Chem (1984) 1.02

Structure of murine complement component C3. II. Nucleotide sequence of cloned complementary DNA coding for the alpha chain. J Biol Chem (1984) 1.01

A specific deletion in the breakpoint cluster region of the ALL-1 gene is associated with acute lymphoblastic T-cell leukemias. Cancer Res (1996) 1.01

The activation of human complement component C5 by a fluid phase C5 convertase. J Biol Chem (1983) 1.00

Exon/intron structure of the human ALL-1 (MLL) gene involved in translocations to chromosomal region 11q23 and acute leukaemias. Br J Haematol (1996) 0.99

Receptors for interleukin-3 (IL-3) and growth hormone mediate an IL-6-type transcriptional induction in the presence of JAK2 or STAT3. Blood (1995) 0.97

Modulation of hepatic acute phase gene expression by epidermal growth factor and Src protein tyrosine kinases in murine and human hepatic cells. Hepatology (1999) 0.94

The LIF response element of the alpha 2 macroglobulin gene confers LIF-induced transcriptional activation in embryonal stem cells. Cytokine (1995) 0.94

Alpha-macroglobulin from Limulus polyphemus exhibits proteinase inhibitory activity and participates in a hemolytic system. Biochemistry (1990) 0.94

The human ALL-1/MLL/HRX antigen is predominantly localized in the nucleus of resting and proliferating peripheral blood mononuclear cells. Cancer Res (1997) 0.90

Prolactin induction of the alpha 2-Macroglobulin gene in rat ovarian granulosa cells: stat 5 activation and binding to the interleukin-6 response element. Mol Endocrinol (1996) 0.89

The role of complement in hemorrhagic shock syndrome (dengue). Trans Assoc Am Physicians (1973) 0.88

The assignment of the genes coding for human complement components C6 and C7 to chromosome 5. Ann Hum Genet (1990) 0.87

Hepatic transcription of the acute-phase alpha 1-inhibitor III gene is controlled by a novel combination of cis-acting regulatory elements. Mol Cell Biol (1990) 0.87

An improved procedure for the generation of recombinant single-chain Fv antibody fragments reacting with human CD13 on intact cells. J Immunol Methods (2001) 0.87

A CD19-specific single-chain immunotoxin mediates potent apoptosis of B-lineage leukemic cells. Leukemia (2007) 0.87

Alpha 2-macroglobulin expression in the mesometrial decidua and its regulation by decidual luteotropin and prolactin. Endocrinology (1992) 0.86

Interleukin 6 response factor binds co-operatively at two adjacent sites in the promoter upstream region of the rat alpha 2-macroglobulin gene. Mol Biol Med (1991) 0.86

Metabolism of radiolabelled C'3 and C'4 in human renal allograft recipients. Transplant Proc (1969) 0.85

ENL, the MLL fusion partner in t(11;19), binds to the c-Abl interactor protein 1 (ABI1) that is fused to MLL in t(10;11)+. Oncogene (2000) 0.84

Infiltration of CD4+ T cells into cornea during development of Onchocerca volvulus-induced experimental sclerosing keratitis in mice. Cell Immunol (1994) 0.84

Autocrine activity of interleukin 6 secreted by hepatocarcinoma cell lines. Mol Biol Med (1991) 0.84

Structural homology of complement protein C6 with other channel-forming proteins of complement. Proc Natl Acad Sci U S A (1989) 0.83

Structure and negative transcriptional regulation by glucocorticoids of the acute-phase rat alpha 1-inhibitor III gene. Biochemistry (1989) 0.83

Formation and structure of the C5b-7 complex of the lytic pathway of complement. J Biol Chem (1992) 0.83

Evaluation of a 74-kDa transferrin-binding protein from Moraxella (Branhamella) catarrhalis as a vaccine candidate. Vaccine (1999) 0.83

Hormonal regulation and tissue-specific localization of alpha 2-macroglobulin in rat ovarian follicles and corpora lutea. Endocrinology (1989) 0.83

Molecular analysis of the chromosomal breakpoint and fusion transcripts in the acute lymphoblastic SEM cell line with chromosomal translocation t(4;11). Br J Haematol (1995) 0.83

Isolation of two interleukin-6 response element binding proteins from acute phase rat livers. Ann N Y Acad Sci (1995) 0.82

Breakpoints of t(4;11) translocations in the human MLL and AF4 genes in ALL patients are preferentially clustered outside of high-affinity matrix attachment regions. J Cell Biochem (2001) 0.82

T-kininogen gene expression is induced during aging. Mol Cell Biol (1989) 0.81

Cytokine-induced expression of leukemia inhibitory factor in renal mesangial cells. Kidney Int (1994) 0.81

Phagocytosis: an overview. Pathol Immunopathol Res (1987) 0.81

Complement C8 deficiency with recurrent meningococcemia: examination of meningococcal opsonization. Aust Paediatr J (1985) 0.81

Sequence of rat alpha 1-macroglobulin, a broad-range proteinase inhibitor from the alpha-macroglobulin-complement family. Mol Biol Med (1991) 0.80

Production of interleukin 6 by hepatoma cells. Mol Biol Med (1990) 0.80

A novel set of hepatic mRNAs preferentially expressed during an acute inflammation in rat represents mostly intracellular proteins. Genomics (1999) 0.80

Effect of age on mitogen induced protein tyrosine phosphorylation in human T cell and its subsets: down-regulation of tyrosine phosphorylation of ZAP-70. Mech Ageing Dev (1998) 0.80

Mitogens and hepatocyte growth control in vivo and in vitro. In Vitro Cell Dev Biol (1990) 0.79

Relationships between the gene and protein structure in human complement component C9. Biochemistry (1988) 0.79

The Interleukin-6-dependent DNA-binding protein gene (transcription factor 5: TCF5) maps to human chromosome 20 and rat chromosome 3, the IL6 receptor locus (IL6R) to human chromosome 1 and rat chromosome 2, and the rat IL6 gene to rat chromosome 4. Genomics (1991) 0.79

Rapid isolation of chromosomal breakpoints from patients with t(4;11) acute lymphoblastic leukemia: implications for basic and clinical research. Cancer Res (1999) 0.79

Molecular cloning, characterization and functional expression of the rat liver interleukin 6 receptor. J Biol Chem (1990) 0.78

Stat 5b and the orphan nuclear receptors regulate expression of the alpha2-macroglobulin (alpha2M) gene in rat ovarian granulosa cells. Mol Endocrinol (1998) 0.78

Interleukin 6 is a negative regulator of the acute phase alpha 1-inhibitor III gene. Mol Biol Med (1990) 0.78

Regulation of CD95 expression and CD95-mediated cell death by interferon-gamma in acute lymphoblastic leukemia with chromosomal translocation t(4;11). Leukemia (1999) 0.78

Identification of a glucocorticoid response element contributing to the constitutive expression of the rat liver alpha 1-inhibitor III gene. J Biol Chem (1991) 0.78

Amino acid sequences of mouse complement C3 derived from nucleotide sequences of cloned cDNA. Ann N Y Acad Sci (1983) 0.78

Immune-mediated Onchocerca volvulus sclerosing keratitis in the mouse. Exp Eye Res (1993) 0.78

Glucocorticoid-stimulated, transcription-independent release of annexin A1 by cochlear Hensen cells. Br J Pharmacol (2009) 0.78

In vivo molecular analysis of cytokines in a murine model of ocular onchocerciasis. I. Up-regulation of IL-4 and IL-5 mRNAs and not IL-2 and IFN gamma mRNAs in the cornea due to experimental interstitial keratitis. Immunol Lett (1996) 0.77

Amino acid sequence of a polymorphic segment from fragment C4d of human complement component C4. FEBS Lett (1983) 0.77

Biochemical characterization of the human complement protein C6. Association with alpha-thrombin-like enzyme and absence of serine protease activity in cytolytically active C6. J Biol Chem (1988) 0.77

Expression of a functional alpha-macroglobulin receptor binding domain in Escherichia coli. FEBS Lett (1992) 0.77

Expression and refolding of a high-affinity receptor binding domain from rat alpha 1-macroglobulin. FEBS Lett (1995) 0.77

Regulation of the rat alpha 2 macroglobulin gene by interleukin 6 and leukemia inhibitory factor. Folia Histochem Cytobiol (1992) 0.77

Characterization of the IL-6/LIF-response factor by proteolytic analysis. Ann N Y Acad Sci (1995) 0.76

The assignment of the human gene coding for complement C5 to chromosome 9q22-9q33. Ann Hum Genet (1988) 0.75

The structure of the human ALL-1/MLL/HRX gene. Leuk Lymphoma (1997) 0.75

Incorporation of photolabile azido fatty acid probes in Neurospora crassa and Saccharomyces cerevisiae. Experientia (1981) 0.75

Rapid isolation of chromosomal breakpoints from patients with t(4;11) acute lymphoblastic leukemia: implications for basic and clinical research. Leukemia (2001) 0.75

Kinetics of the activation of the LIF-response factor in M1 myeloid leukemic cells. Ann N Y Acad Sci (1995) 0.75

Dr. B. C. Das Gupta Memorial Oration. Indian J Public Health (1970) 0.75

Renal mesangial cells have the capacity to synthesize and react to leukemia inhibitory factor. Ann N Y Acad Sci (1995) 0.75

The expression of interleukin-6 by a rat macrophage-derived cell line. FEBS Lett (1991) 0.75

Pro-C4 of human plasma: isolation and description of chemical and antigenic properties. Ann N Y Acad Sci (1980) 0.75

Role of de novo protein synthesis by human mononuclear leukocytes in opsonin-independent phagocytosis. Cell Immunol (1994) 0.75

Recent advances in the study of the molecular structure of the complement proteins. Pathol Immunopathol Res (1986) 0.75