Published in Eur J Biochem on July 01, 1988
Maitotoxin activates cation channels distinct from the receptor-activated non-selective cation channels of HL-60 cells. Biochem J (1994) 0.87
Inhibition of muscarinic receptor-induced inositol phospholipid hydrolysis by caffeine, beta-adrenoceptors and protein kinase C in intestinal smooth muscle. Br J Pharmacol (1995) 0.86
Ca(2+)-dependent aggregation of rabbit platelets induced by maitotoxin, a potent marine toxin, isolated from a dinoflagellate. Br J Pharmacol (1993) 0.84
Complex interactions of agonists with alpha 1-adrenoceptors in intact cells. Br J Pharmacol (1988) 0.77
Non classical, multiple-site interaction of [3H]-prazosin with the alpha 1-adrenoceptor of intact BC3H1 cells. Br J Pharmacol (1989) 0.75
Differential signal transduction by five splice variants of the PACAP receptor. Nature (1993) 3.38
NMDA-dependent superoxide production and neurotoxicity. Nature (1993) 2.79
The effect of chaotropic ions on the dissociation of antigen-antibody complexes. Biochemistry (1967) 2.52
The gastrointestinal prokinetic benzamide derivatives are agonists at the non-classical 5-HT receptor (5-HT4) positively coupled to adenylate cyclase in neurons. Naunyn Schmiedebergs Arch Pharmacol (1989) 2.31
Metabotropic glutamate receptors: from the workbench to the bedside. Neuropharmacology (2010) 2.31
Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer. Nature (2001) 2.28
A nonclassical 5-hydroxytryptamine receptor positively coupled with adenylate cyclase in the central nervous system. Mol Pharmacol (1988) 2.15
Glutamate stimulates inositol phosphate formation in striatal neurones. Nature (1985) 2.02
Reassessment of Clostridium difficile susceptibility to metronidazole and vancomycin. Antimicrob Agents Chemother (2002) 2.00
A European survey of diagnostic methods and testing protocols for Clostridium difficile. Clin Microbiol Infect (2003) 1.94
Taxonomy of four marine bacterial strains that produce tetrodotoxin. Int J Syst Bacteriol (1990) 1.91
Functional coupling between ryanodine receptors and L-type calcium channels in neurons. Nature (1996) 1.81
"Inflammatory" cytokines: neuromodulators in normal brain? J Neurochem (2000) 1.80
Localization and mechanisms of action of cannabinoid receptors at the glutamatergic synapses of the mouse nucleus accumbens. J Neurosci (2001) 1.69
Biochemical and pharmacological characterisation of SR141716A, the first potent and selective brain cannabinoid receptor antagonist. Life Sci (1995) 1.68
An alpha 40 subunit of a GTP-binding protein immunologically related to Go mediates a dopamine-induced decrease of Ca2+ current in snail neurons. Neuron (1988) 1.68
Detection of sodium channel toxins: directed cytotoxicity assays of purified ciguatoxins, brevetoxins, saxitoxins, and seafood extracts. J AOAC Int (1995) 1.63
Regulation of apoptosis and cell cycle arrest by Zac1, a novel zinc finger protein expressed in the pituitary gland and the brain. EMBO J (1997) 1.60
Pituitary adenylate cyclase-activating polypeptide (PACAP-38) protects cerebellar granule neurons from apoptosis by activating the mitogen-activated protein kinase (MAP kinase) pathway. J Neurosci (1997) 1.58
NMDA receptors activate the arachidonic acid cascade system in striatal neurons. Nature (1988) 1.55
Pharmacological and functional characteristics of metabotropic excitatory amino acid receptors. Trends Pharmacol Sci (1990) 1.53
Specific binding of (3H) lysine-vasopressin to pig kidney plasma membranes. Relationship of receptor occupancy to adenylate cyclase activation. J Biol Chem (1973) 1.52
"Second-look" cytotoxicity: an evaluation of culture plus cytotoxin assay of Clostridium difficile isolates in the laboratory diagnosis of CDAD. J Hosp Infect (2001) 1.49
Multicenter evaluation of the COBAS AMPLICOR HCV assay, an integrated PCR system for rapid detection of hepatitis C virus RNA in the diagnostic laboratory. J Clin Microbiol (1998) 1.47
Quantification of CD1a, HLA-DR, and HLA class I expression on viable human Langerhans cells and keratinocytes. Cytometry (1996) 1.47
Production of tetrodotoxin and its derivatives by Pseudomonas sp. isolated from the skin of a pufferfish. Toxicon (1987) 1.47
Complex interactions between mGluRs, intracellular Ca2+ stores and ion channels in neurons. Trends Neurosci (2000) 1.45
Dendritic and axonal targeting of type 5 metabotropic glutamate receptor is regulated by homer1 proteins and neuronal excitation. J Neurosci (2000) 1.43
A 5-HT receptor in the central nervous system, positively coupled with adenylate cyclase, is antagonized by ICS 205 930. Eur J Pharmacol (1988) 1.43
Cytokine signals propagate through the brain. Mol Psychiatry (2000) 1.42
BAY36-7620: a potent non-competitive mGlu1 receptor antagonist with inverse agonist activity. Mol Pharmacol (2001) 1.41
Diffusion tensor imaging and voxel based morphometry study in early progressive supranuclear palsy. J Neurol Neurosurg Psychiatry (2005) 1.40
hZAC encodes a zinc finger protein with antiproliferative properties and maps to a chromosomal region frequently lost in cancer. Proc Natl Acad Sci U S A (1998) 1.38
Two analogs of azaspiracid isolated from mussels, Mytilus edulis, involved in human intoxication in Ireland. Nat Toxins (1999) 1.38
Physical interaction between the serotonin transporter and neuronal nitric oxide synthase underlies reciprocal modulation of their activity. Proc Natl Acad Sci U S A (2007) 1.38
Direct activation of GTP-binding regulatory proteins (G-proteins) by substance P and compound 48/80. FEBS Lett (1990) 1.37
Multicenter study of a commercial, automated polymerase chain reaction system for the rapid detection of Mycobacterium tuberculosis in respiratory specimens in routine clinical practice. Eur J Clin Microbiol Infect Dis (2001) 1.37
Nitric oxide-induced blockade of NMDA receptors. Neuron (1992) 1.35
Hormone-stimulated desensitization of hormone-dependent adenylyl cyclase. Dual action of luteninizing hormone on pig graafian follicle membranes. J Biol Chem (1976) 1.33
The structure elucidation and biological activities of high molecular weight algal toxins: maitotoxin, prymnesins and zooxanthellatoxins. Nat Prod Rep (2000) 1.31
Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1. J Neurosci (1995) 1.29
New saxitoxin analogues from the freshwater filamentous cyanobacterium Lyngbya wollei. Nat Toxins (1997) 1.28
Interaction of serotonin 5-hydroxytryptamine type 2C receptors with PDZ10 of the multi-PDZ domain protein MUPP1. J Biol Chem (2001) 1.27
The vasopressin-sensitive adenylate cyclase of the rat kidney. Effect of adrenalectomy and corticosteroids on hormonal receptor-enzyme coupling. J Biol Chem (1974) 1.25
A new mechanism for glutamate receptor action: phosphoinositide hydrolysis. Trends Neurosci (1988) 1.24
Domains involved in the specificity of G protein activation in phospholipase C-coupled metabotropic glutamate receptors. EMBO J (1994) 1.24
Presence of three pertussis toxin substrates and Go alpha immunoreactivity in both plasma and granule membranes of chromaffin cells. FEBS Lett (1987) 1.24
Novel brain-specific 5-HT4 receptor splice variants show marked constitutive activity: role of the C-terminal intracellular domain. Mol Pharmacol (1999) 1.24
Multiple organ damage caused by a new toxin azaspiracid, isolated from mussels produced in Ireland. Toxicon (2000) 1.23
Oxytocin-sensitive adenylate cyclase in frog bladder epithelial cells. Role of calcium, nucleotides, and other factors in hormonal stimulation. J Biol Chem (1972) 1.23
Pharmacological characterization of the D2 dopamine receptor negatively coupled with adenylate cyclase in rat anterior pituitary. Mol Pharmacol (1983) 1.22
Changes in the carboxyl-terminal domain of metabotropic glutamate receptor 1 by alternative splicing generate receptors with differing agonist-independent activity. Mol Pharmacol (1996) 1.21
Structures of azaspiracid analogs, azaspiracid-4 and azaspiracid-5, causative toxins of azaspiracid poisoning in Europe. Biosci Biotechnol Biochem (2001) 1.20
PAC1 receptor-deficient mice display impaired insulinotropic response to glucose and reduced glucose tolerance. J Clin Invest (2000) 1.19
Loss of expression of the candidate tumor suppressor gene ZAC in breast cancer cell lines and primary tumors. Oncogene (1999) 1.19
Inhibitory effect of okadaic acid derivatives on protein phosphatases. A study on structure-affinity relationship. Biochem J (1992) 1.18
Arachidonic acid released from striatal neurons by joint stimulation of ionotropic and metabotropic quisqualate receptors. Nature (1990) 1.18
Maitotoxin, a Ca2+ channel activator candidate. J Biol Chem (1982) 1.18
5-HT1B receptors are negatively coupled with adenylate cyclase in rat substantia nigra. Eur J Pharmacol (1988) 1.17
First occurrence of tetrodotoxin in a dendrobatid frog (Colostethus inguinalis), with further reports for the bufonid genus Atelopus. Toxicon (1994) 1.17
A modified method for the indirect quantitative analysis of phytate in foodstuffs. Anal Biochem (1995) 1.16
A protein phosphatase 2A inhibition assay for a fast and sensitive assessment of okadaic acid contamination in mussels. Toxicon (1996) 1.16
Comparison of oral and intraperitoneal toxicity of yessotoxin towards mice. Toxicon (2002) 1.16
A simple method to transfer plasmid DNA into neuronal primary cultures: functional expression of the mGlu5 receptor in cerebellar granule cells. Neuropharmacology (1999) 1.16
Differential G protein-mediated coupling of D2 dopamine receptors to K+ and Ca2+ currents in rat anterior pituitary cells. Neuron (1992) 1.15
Central 5-HT4 receptors. Trends Pharmacol Sci (1995) 1.15
The second intracellular loop of metabotropic glutamate receptor 1 cooperates with the other intracellular domains to control coupling to G-proteins. J Biol Chem (1996) 1.12
Glutamate stimulates glucagon secretion via an excitatory amino acid receptor of the AMPA subtype in rat pancreas. Eur J Pharmacol (1993) 1.11
Cloning and functional expression of a Drosophila metabotropic glutamate receptor expressed in the embryonic CNS. J Neurosci (1996) 1.11
Alternative splicing generates metabotropic glutamate receptors inducing different patterns of calcium release in Xenopus oocytes. Proc Natl Acad Sci U S A (1992) 1.11
D2-dopamine receptor-mediated inhibition of cyclic AMP formation in striatal neurons in primary culture. Mol Pharmacol (1985) 1.11
Pharmacology of 5-hydroxytryptamine-1A receptors which inhibit cAMP production in hippocampal and cortical neurons in primary culture. Mol Pharmacol (1988) 1.10
Visualization of cyclic AMP-regulated presynaptic activity at cerebellar granule cells. Neuron (1998) 1.10
Origins of ciguatera fish poisoning: a new dinoflagellate, Gambierdiscus toxicus Adachi and Fukuyo, definitively involved as a causal agent. Toxicon (1980) 1.09
Metabotropic glutamate receptors in the rat nucleus accumbens. Eur J Neurosci (1997) 1.09
The Ca2+/C1- dependent L-[3H]glutamate binding: a new receptor or a particular transport process? FEBS Lett (1984) 1.08
Adenylyl cyclase activities in ovarian tissues. I. Homogenization and conditions of assay in graafian follicles and corpora lutea of rabbits, rats, and pigs: regulation by ATP, and some comparative properties. Endocrinology (1976) 1.08
Comparative effect of L-CCG-I, DCG-IV and gamma-carboxy-L-glutamate on all cloned metabotropic glutamate receptor subtypes. Neuropharmacology (1998) 1.07
Synaptogenesis of cultured striatal neurons in serum-free medium: a morphological and biochemical study. Proc Natl Acad Sci U S A (1986) 1.07
Selective blockade of P/Q-type calcium channels by the metabotropic glutamate receptor type 7 involves a phospholipase C pathway in neurons. J Neurosci (2000) 1.07
Dinoflagellate Gymnodinium catenatum as the source of paralytic shellfish toxins in Tasmanian shellfish. Toxicon (1987) 1.07
Use of (-)-[3H]dihydroalprenolol to study beta adrenergic receptor-adenylate cyclase coupling in C6 glioma cells: role of 5'-guanylylimidodiphosphate. Mol Pharmacol (1977) 1.07
Electrospray ionization mass spectrometry of tetrodotoxin and its analogs: liquid chromatography/mass spectrometry, tandem mass spectrometry, and liquid chromatography/tandem mass spectrometry. Anal Biochem (2001) 1.07
Enhancement of 5-fluorouracil cytotoxicity by human thymidine-phosphorylase expression in cancer cells: in vitro and in vivo study. Int J Cancer (1999) 1.06
Diarrhetic shellfish toxin, dinophysistoxin-1, is a potent tumor promoter on mouse skin. Jpn J Cancer Res (1988) 1.06
Aplysiatoxin and debromoaplysiatoxin as the causative agents of a red alga Gracilaria coronopifolia poisoning in Hawaii. Toxicon (1996) 1.06
Get receptive to metabotropic glutamate receptors. Curr Opin Neurobiol (1995) 1.06
Some chemical properties of maitotoxin, a putative calcium channel agonist isolated from a marine dinoflagellate. J Biochem (1988) 1.05
Clinical manifestations, treatment and control of infections caused by Clostridium difficile. Clin Microbiol Infect (2005) 1.05
BRL 24924: a potent agonist at a non-classical 5-HT receptor positively coupled with adenylate cyclase in colliculi neurons. Eur J Pharmacol (1989) 1.05
Characterization of the methylation-sensitive promoter of the imprinted ZAC gene supports its role in transient neonatal diabetes mellitus. J Biol Chem (2001) 1.05
Interaction of substance P, compound 48/80 and mastoparan with the alpha-subunit C-terminus of G protein. Immunol Lett (1990) 1.04
Phenylglycine derivatives discriminate between mGluR1- and mGluR5-mediated responses. Neuropharmacology (1995) 1.04
Combined effects of GSTP1 and MRP1 in melanoma drug resistance. Br J Cancer (2005) 1.04
Serotonin increases calcium current in human atrial myocytes via the newly described 5-hydroxytryptamine4 receptors. Mol Pharmacol (1992) 1.04
In vitro activity of ramoplanin against Clostridium difficile, including strains with reduced susceptibility to vancomycin or with resistance to metronidazole. Antimicrob Agents Chemother (2005) 1.03
Evidence of nosocomial Stenotrophomonas maltophilia cross-infection in a neonatology unit analyzed by three molecular typing methods. Infect Control Hosp Epidemiol (1999) 1.03