Published in Proc Natl Acad Sci U S A on December 01, 1987
Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease. J Clin Invest (2002) 2.07
U3 small nuclear RNA can be psoralen-cross-linked in vivo to the 5' external transcribed spacer of pre-ribosomal-RNA. Proc Natl Acad Sci U S A (1989) 2.00
Polycystin-1 C-terminal tail associates with beta-catenin and inhibits canonical Wnt signaling. Hum Mol Genet (2008) 1.62
Molecular regulation of kidney development: is the answer blowing in the Wnt? Pediatr Nephrol (2007) 1.52
Polycystin-1, the PKD1 gene product, is in a complex containing E-cadherin and the catenins. J Clin Invest (1999) 1.41
Contrasting expression patterns of three members of the myc family of protooncogenes in the developing and adult mouse kidney. J Cell Biol (1991) 1.23
Renal epithelial cyst formation and enlargement in vitro: dependence on cAMP. Proc Natl Acad Sci U S A (1989) 1.19
Differential rescue of the renal and hepatic disease in an autosomal recessive polycystic kidney disease mouse mutant. A new model to study the liver lesion. Am J Pathol (1997) 1.05
Patterns of mRNA expression during early cell growth differ in kidney epithelial cells destined to undergo compensatory hypertrophy versus regenerative hyperplasia. Proc Natl Acad Sci U S A (1988) 0.96
mTORC1/2 and rapamycin in female Han:SPRD rats with polycystic kidney disease. Am J Physiol Renal Physiol (2010) 0.87
Polycystic kidney disease and cancer after renal transplantation. J Am Soc Nephrol (2014) 0.85
Analysis of the role of membrane polarity in polycystic kidney disease of transgenic SBM mice. Am J Pathol (1995) 0.84
Therapeutic targeting of BET bromodomain protein, Brd4, delays cyst growth in ADPKD. Hum Mol Genet (2015) 0.84
Metal-inducible pathology in the liver, pancreas, and kidney of transgenic mice expressing SV40 early region genes. Am J Pathol (1989) 0.83
The proto-oncoprotein SYT (SS18) controls ATP release and regulates cyst formation by polarized MDCK cells. Exp Cell Res (2008) 0.78
c-myc protein distribution. Neoplastic tissues of the human colon. Am J Pathol (1992) 0.76
Mouse models of polycystic kidney disease induced by defects of ciliary proteins. BMB Rep (2013) 0.76
Deletion of ADP Ribosylation Factor-Like GTPase 13B Leads to Kidney Cysts. J Am Soc Nephrol (2016) 0.75
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry (1979) 180.95
Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. Proc Natl Acad Sci U S A (1980) 109.70
Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. Nature (1984) 24.45
Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature (1983) 19.76
Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor. Cell (1983) 17.87
Induction of c-fos gene and protein by growth factors precedes activation of c-myc. Nature (1985) 9.73
The molecular genetics of cancer. Science (1987) 7.64
A highly polymorphic DNA marker linked to adult polycystic kidney disease on chromosome 16. Nature (1985) 7.34
Regulation of human histone gene expression: kinetics of accumulation and changes in the rate of synthesis and in the half-lives of individual histone mRNAs during the HeLa cell cycle. Mol Cell Biol (1983) 7.01
Cell-cycle control of c-myc but not c-ras expression is lost following chemical transformation. Cell (1984) 6.53
Extreme instability of myc mRNA in normal and transformed human cells. Proc Natl Acad Sci U S A (1984) 5.09
Differential expression of cellular oncogenes during pre- and postnatal development of the mouse. Nature (1982) 4.44
Evolution of tumours and the impact of molecular oncology. Nature (1985) 4.24
Differential expression of myc family genes during murine development. Nature (1986) 3.57
The structure of the human histone genes: clustered but not tandemly repeated. Cell (1981) 3.47
C-myc transcript is induced in rat liver at a very early stage of regeneration or by cycloheximide treatment. Nature (1984) 2.63
Close link between reduction of c-myc expression by interferon and, G0/G1 arrest. Nature (1985) 2.47
Participation of c-myc protein in DNA synthesis of human cells. Science (1986) 2.22
Regulated transcription of c-Ki-ras and c-myc during compensatory growth of rat liver. Mol Cell Biol (1984) 1.98
The regulation and expression of c-myc in normal and malignant cells. Annu Rev Immunol (1986) 1.90
Ultrastructure and function of cysts from human adult polycystic kidneys. Kidney Int (1980) 1.34
The biology of renal hypertrophy. Kidney Int (1986) 1.30
Acquired cystic disease: replacing one kidney disease with another. Kidney Int (1985) 1.15
Renal epithelial hyperplastic and neoplastic proliferation in autosomal dominant polycystic kidney disease. Am J Kidney Dis (1987) 1.11
The pathogenesis of drug-induced renal cystic disease. Kidney Int (1974) 1.05
Polycystic kidney disease: a predominance of giant nephrons. Am J Physiol (1983) 1.03
Polypoid and papillary epithelial hyperplasia: a potential cause of ductal obstruction in adult polycystic disease. Kidney Int (1979) 1.02
Chemically induced renal hypertrophy in the rat. Lab Invest (1973) 0.90
Cell proliferation in mouse kidney after a single injection of folic acid. Lab Invest (1968) 0.88
Folic acid-induced renal injury and repair. Correlation of structural and functional abnormalities. Arch Pathol Lab Med (1980) 0.87
Specific gene expression during compensatory renal hypertrophy in the rat. J Cell Physiol (1987) 0.85
Comparison of human polycystic and medullary cystic kidney disease with diphenylamine-induced cystic disease. Lab Invest (1976) 0.82
Congenital polycystic kidney disease. Genetically transmitted infantile polycystic kidney disease in C57BL/6J mice. Am J Pathol (1983) 0.81
Effect of vasopressin and cyclic AMP on permeability of isolated collecting tubules. Am J Physiol (1966) 4.19
U6 small nuclear RNA is transcribed by RNA polymerase III. Proc Natl Acad Sci U S A (1986) 3.14
Effect of prostaglandin E1 on the permeability response of the isolated collecting tubule to vasopressin, adenosine 3',5'-monophosphate, and theophylline. J Clin Invest (1968) 2.76
cAMP stimulates the in vitro proliferation of renal cyst epithelial cells by activating the extracellular signal-regulated kinase pathway. Kidney Int (2000) 2.65
Base-pairing interactions between small nuclear RNAs and nuclear RNA precursors as revealed by psoralen cross-linking in vivo. Cell (1981) 2.49
Cyst formation and growth in autosomal dominant polycystic kidney disease. Kidney Int (1987) 2.16
Ultrastructural studies of vasopressin effect on isolated perfused renal collecting tubules of the rabbit. J Cell Biol (1968) 2.06
U3 small nuclear RNA can be psoralen-cross-linked in vivo to the 5' external transcribed spacer of pre-ribosomal-RNA. Proc Natl Acad Sci U S A (1989) 2.00
The nature of transtubular Na and K transport in isolated rabbit renal collecting tubules. J Clin Invest (1970) 1.88
Physical properties of isolated perfused renal tubules and tubular basement membranes. J Clin Invest (1972) 1.86
Calcium channel inhibition accelerates polycystic kidney disease progression in the Cy/+ rat. Kidney Int (2007) 1.83
Exacerbation of familial renal lymphangiomatosis during pregnancy. AJR Am J Roentgenol (1988) 1.75
Renal cysts in transgenic mice expressing transforming growth factor-alpha. J Lab Clin Med (1994) 1.66
Effect of vasopressin on electrical resistance of renal cortical collecting tubules. Am J Physiol (1971) 1.65
Paths of transtubular water flow in isolated renal collecting tubules. J Cell Biol (1969) 1.57
The genetics and physiology of polycystic kidney disease. Semin Nephrol (2001) 1.57
The polycystic kidney disease-1 protein, polycystin-1, binds and activates heterotrimeric G-proteins in vitro. Biochem Biophys Res Commun (1998) 1.55
Small nuclear RNA U2 is base-paired to heterogeneous nuclear RNA. Science (1982) 1.53
Epithelial transport in polycystic kidney disease. Physiol Rev (1998) 1.45
Autosomal-dominant polycystic kidney disease in the rat. Kidney Int (1993) 1.44
Regulation of renal tubule cell volume in hypotonic media. Am J Physiol (1973) 1.39
Ultrastructure and function of cysts from human adult polycystic kidneys. Kidney Int (1980) 1.34
Secondary structure of heterogeneous nuclear RNA: two classes of double-stranded RNA in native ribonucleoprotein. Proc Natl Acad Sci U S A (1977) 1.31
The cystic fibrosis transmembrane conductance regulator mediates transepithelial fluid secretion by human autosomal dominant polycystic kidney disease epithelium in vitro. Kidney Int (1996) 1.28
The heat shock response in HeLa cells is accompanied by elevated expression of the c-fos proto-oncogene. Mol Cell Biol (1987) 1.28
Volumetric determination of progression in autosomal dominant polycystic kidney disease by computed tomography. Kidney Int (2000) 1.22
Elevated proto-oncogene expression in polycystic kidneys of the C57BL/6J (cpk) mouse. J Am Soc Nephrol (1991) 1.22
The secretion of fluid by renal cysts from patients with autosomal dominant polycystic kidney disease. N Engl J Med (1993) 1.22
Renal epithelial cyst formation and enlargement in vitro: dependence on cAMP. Proc Natl Acad Sci U S A (1989) 1.19
A hereditary model of slowly progressive polycystic kidney disease in the mouse. J Am Soc Nephrol (1991) 1.16
Renal accumulation and excretion of cyclic adenosine monophosphate in a murine model of slowly progressive polycystic kidney disease. Am J Kidney Dis (1997) 1.16
Acquired cystic disease: replacing one kidney disease with another. Kidney Int (1985) 1.15
Nucleoprotein organization of inverted repeat DNA transcripts in heterogeneous nuclear RNA-ribonucleoprotein particles from HeLa cells. J Mol Biol (1978) 1.15
Immunolocalization of ion transport proteins in human autosomal dominant polycystic kidney epithelial cells. Proc Natl Acad Sci U S A (1996) 1.15
Heterogeneous nuclear RNA double-stranded regions probed in living HeLa cells by crosslinking with the psoralen derivative aminomethyltrioxsalen. Proc Natl Acad Sci U S A (1979) 1.15
Renal epithelial fluid secretion and cyst growth: the role of cyclic AMP. FASEB J (1989) 1.13
Development of autosomal recessive polycystic kidney disease in BALB/c-cpk/cpk mice. J Am Soc Nephrol (2000) 1.09
Fluid secretion in isolated proximal straight renal tubules. Effect of human uremic serum. J Clin Invest (1973) 1.08
Polycystic kidney disease: etiology, pathogenesis, and treatment. Dis Mon (1995) 1.08
Polycystin-1 transforms the cAMP growth-responsive phenotype of M-1 cells. Kidney Int (2001) 1.08
Chloride and fluid secretion by cultured human polycystic kidney cells. Kidney Int (1996) 1.06
The role of computed tomography in the evaluation of adult polycystic kidney disease. Am J Kidney Dis (1981) 1.06
Natural history of acquired renal cystic disease in dialysis patients: a prospective longitudinal CT study. AJR Am J Roentgenol (1991) 1.05
Vanadate-stimulated natriuresis. Nature (1978) 1.05
Temperature effect on ADH response of isolated perfused rabbit collecting tubules. Am J Physiol (1980) 1.03
Anion secretion drives fluid secretion by monolayers of cultured human polycystic cells. Am J Physiol (1995) 1.03
Polycystic kidney disease: a predominance of giant nephrons. Am J Physiol (1983) 1.03
C-fos expression is hypersensitive to serum-stimulation in cultured cystic kidney cells from the C57BL/6J-cpk mouse. J Cell Physiol (1992) 1.01
Evidence for internal homology in bovine preproparathyroid hormone. Proc Natl Acad Sci U S A (1979) 1.00
The SGP-2 gene is developmentally regulated in the mouse kidney and abnormally expressed in collecting duct cysts in polycystic kidney disease. Dev Biol (1991) 0.99
Modification of disease progression in rats with inherited polycystic kidney disease. Am J Kidney Dis (1996) 0.99
Calcified renal stones and cyst calcifications in autosomal dominant polycystic kidney disease: clinical and CT study in 84 patients. AJR Am J Roentgenol (1992) 0.99
Isovolumetric regulation of isolated S2 proximal tubules in anisotonic media. J Clin Invest (1986) 0.98
Mouse plasma glutathione peroxidase. cDNA sequence analysis and renal proximal tubular expression and secretion. J Biol Chem (1994) 0.98
Influence of serum proteins on net fluid reabsorption of isolated proximal tubules. Kidney Int (1972) 0.98
Liver cysts in autosomal-dominant polycystic kidney disease: clinical and computed tomographic study. AJR Am J Roentgenol (1985) 0.97
A synthetic peptide derived from glycine-gated Cl- channel induces transepithelial Cl- and fluid secretion. Am J Physiol (1997) 0.97
Autosomal recessive polycystic kidney disease in a murine model. A gross and microscopic description. Lab Invest (1988) 0.96
In vitro formation and expansion of cysts derived from human renal cortex epithelial cells. Kidney Int (1992) 0.95
cAMP-dependent fluid secretion in rat inner medullary collecting ducts. Am J Physiol Renal Physiol (2001) 0.95
The effects of vanadate on the fluxes of sodium and potassium ions through the sodium pump. J Physiol (1980) 0.95
Vasopressin: effect on deformability of urinary surface of collecting duct cells. Science (1970) 0.95
Chloride and fluid secretion in polycystic kidney disease. J Am Soc Nephrol (1998) 0.95
Effect of lovastatin on the development of polycystic kidney disease in the Han:SPRD rat. Am J Kidney Dis (1995) 0.95
Isolation and partial characterization of secretory protein I from bovine parathyroid glands. Biochemistry (1981) 0.95
Matrix metalloproteinases and TIMPS in cultured C57BL/6J-cpk kidney tubules. Kidney Int (1996) 0.94
Cyst fluid from human autosomal dominant polycystic kidneys promotes cyst formation and expansion by renal epithelial cells in vitro. J Am Soc Nephrol (1992) 0.91
Localization of overexpressed c-myc mRNA in polycystic kidneys of the cpk mouse. Kidney Int (1992) 0.91
Studies of isolated renal tubules in vitro. Annu Rev Physiol (1978) 0.91
A clinical index to predict survival in acute renal failure patients requiring dialysis. Am J Kidney Dis (1988) 0.91
A synthetic channel-forming peptide induces Cl(-) secretion: modulation by Ca(2+)-dependent K(+) channels. Biochim Biophys Acta (2000) 0.90
Cellular aspects of renal sodium transport and cell volume regulation. Kidney Int (1976) 0.90
Carbon dioxide dissociation curve in potassium depletion. Am J Physiol (1967) 0.89
Effect of hypotonic medium on K and Na content of proximal renal tubules. Am J Physiol (1977) 0.89
Renal expression of a transforming growth factor-alpha transgene accelerates the progression of inherited, slowly progressive polycystic kidney disease in the mouse. J Lab Clin Med (1996) 0.88
Photochemical cross-linking of secondary structure in HeLa cell heterogeneous nuclear RNA in situ 1. Nucleic Acids Res (1979) 0.88
Matrix metalloproteinase-2 in a murine model of infantile-type polycystic kidney disease. J Am Soc Nephrol (1999) 0.87
Secretory activity and aryl acid content of serum, urine, and cerebrospinal fluid in normal and uremic man. J Lab Clin Med (1975) 0.87
Renal Na,K-ATPase: determinants of inhibition by vanadium. Am J Physiol (1979) 0.87
Defective epidermal growth factor gene expression in mice with polycystic kidney disease. Dev Biol (1990) 0.86
Mode of water transport in mammalian renal collecting tubules. Fed Proc (1971) 0.86
Spontaneous subcapsular and perinephric hemorrhage in end-stage kidney disease: clinical and CT findings. AJR Am J Roentgenol (1987) 0.85
Cyst fluid from a murine model of polycystic kidney disease stimulates fluid secretion, cyclic adenosine monophosphate accumulation, and cell proliferation by Madin-Darby canine kidney cells in vitro. Am J Kidney Dis (1995) 0.85
Kid-1 expression is high in differentiated renal proximal tubule cells and suppressed in cyst epithelia. Am J Physiol (1998) 0.85
Identification of the major site of in vitro PKA phosphorylation in the polycystin-1 C-terminal cytosolic domain. Biochem Biophys Res Commun (1999) 0.84
Transepithelial water permeability in an in vitro model of renal cysts. J Am Soc Nephrol (1990) 0.84
Methylprednisolone retards the progression of inherited polycystic kidney disease in rodents. Am J Kidney Dis (1995) 0.84
The single nephron preparation--cortical collecting tubules. Yale J Biol Med (1973) 0.83
Understanding human cystic disease through experimental models. Semin Nephrol (1991) 0.83
Coupling of cell volume and membrane potential changes to fluid secretion in a model of renal cysts. Kidney Int (1994) 0.83