Published in Nature on May 25, 1978
Shared antigenic determinants by mitogen receptors and antibody molecules to the same thymus-independent antigen. J Exp Med (1978) 0.92
Acinetobacter and E. coli lipopolysaccharide preparations comparative mitogenicity and induction in vitro of immunoglobulin synthesis in adult and neonatal pig lymphocytes. Immunology (1979) 0.89
The binding of LPS to the lymphocyte surface. Immunology (1979) 0.87
Lipopolysaccharide induces retroviral antigen expression in 129/J mouse lymphocytes: evidence for assembly of a defective viral particle. J Virol (1981) 0.85
A dichotomy between the expression of IgD on B cells and its requirement for triggering such cells with two T-independent antigens. J Exp Med (1979) 0.83
Immunoglobulin receptor signaling depends on the carboxyl terminus but not the heavy-chain class. Proc Natl Acad Sci U S A (1989) 0.81
B-cell subsets responsive to fluorescein-conjugated antigens. III. Differential effect of E. Coli lipopolysaccharide on T-dependent and T-independent responses in vivo. Immunology (1979) 0.81
Polyclonal B-cell activation by a synthetic analogue of bacterial lipoprotein is functionally different from activation by bacterial lipopolysaccharide. Immunology (1987) 0.77
Interactions between lymphocyte membrane molecules. I. Interaction between B lymphocyte surface IgM and Fc IgG receptors requires ligand occupancy of both receptors. J Exp Med (1981) 0.76
A plaque assay for all cells secreting Ig of a given type or class. Eur J Immunol (1976) 9.11
Immunoglobulin spots on the surface of rabbit lymphocytes. J Exp Med (1970) 8.87
Routine versus clinically driven laboratory monitoring of HIV antiretroviral therapy in Africa (DART): a randomised non-inferiority trial. Lancet (2009) 7.96
The dynamic state of the lymphocyte membrane. Factors affecting the distribution and turnover of surface immunoglobulins. Eur J Immunol (1972) 7.05
Immunoglobulin D as a lymphocyte receptor. J Exp Med (1973) 4.62
Two distinct factors are required for induction of T-cell growth. Nature (1980) 4.13
Thymus-independent B-cell induction and paralysis. Adv Immunol (1975) 3.27
The role of mitogenic lectins in T-cell triggering. Nature (1979) 3.26
Immunoglobulins as cell receptors. Ann N Y Acad Sci (1971) 3.25
Clonal growth and maturation to immunoglobulin secretion in vitro of every growth-inducible B lymphocyte. Cell (1977) 3.23
Second generation immune networks. Immunol Today (1991) 2.97
Editorial: Immune activation of B cells: evidence for 'one nonspecific triggering signal' not delivered by the Ig receptors. Scand J Immunol (1974) 2.93
Analysis of the neuroligin 3 and 4 genes in autism and other neuropsychiatric patients. Mol Psychiatry (2005) 2.78
Frequencies of mitogen-reactive B cells in the mouse. I. Distribution in different lymphoid organs from different inbred strains of mice at different ages. J Exp Med (1977) 2.68
Studies on T lymphocyte activation. I. Requirements for the mitogen-dependent production of T cell growth factors. Eur J Immunol (1979) 2.59
Clinical pharmacology of platelet cyclooxygenase inhibition. Circulation (1985) 2.46
Extrathymic origin of intestinal intraepithelial lymphocytes bearing T-cell antigen receptor gamma delta. Proc Natl Acad Sci U S A (1991) 2.46
Specific T helper cells that activate B cells polyclonally. In vitro enrichment and cooperative function. J Exp Med (1980) 2.27
Localization of gamma/delta T cells to the intestinal epithelium is independent of normal microbial colonization. J Exp Med (1990) 2.23
Selective triggering of B cell subpopulations by mitogens. Eur J Immunol (1974) 2.22
Functional analysis of B cell heterogeneity. Transplant Rev (1975) 2.17
High frequency of natural autoantibodies in normal newborn mice. J Immunol (1985) 2.17
The conjugation of immunoglobulins with tetramethylrhodamine isothiocyanate. A comparison between the amorphous and the crystalline fluorochrome. J Immunol Methods (1972) 2.11
Studies on T lymphocyte activation II. The target cells for concanavalin A-induced growth factors. Eur J Immunol (1979) 2.10
Mechanism of thymus-independent immunocyte triggering. Mitogenic activation of B cells results in specific immune responses. J Exp Med (1974) 2.04
A B-cell mitogen from a pathogenic trypanosome is a eukaryotic proline racemase. Nat Med (2000) 2.01
Live adult worms detected by ultrasonography in human Bancroftian filariasis. Am J Trop Med Hyg (1994) 1.90
Molecular basis of B-cell activation. I. Mitogenicity of native and substituted dextrans. Scand J Immunol (1974) 1.87
Genetic defect in responsiveness to the B cell mitogen lipopolysaccharide. Eur J Immunol (1977) 1.83
All T15 Id-positive antibodies (but not the majority of VHT15+ antibodies) are produced by peritoneal CD5+ B lymphocytes. Int Immunol (1990) 1.82
Para-aortic splanchnopleura from early mouse embryos contains B1a cell progenitors. Nature (1993) 1.82
B cell mitogenic properties of thymus-independent antigens. Nat New Biol (1973) 1.80
Synthesis of multiple immunoglobulin classes by single lymphocytes. Cold Spring Harb Symp Quant Biol (1977) 1.76
Genetic control of B-cell responses. I. Selective unresponsiveness to lipopolysaccharide. Scand J Immunol (1975) 1.71
Blocking and redistribution ("capping") of antigen receptors on T and B lymphocytes by anti-immunoglobulin antibody. J Exp Med (1973) 1.63
In vitro activation of mouse lymphocytes in serum-free medium: effect of T and B cell mitogens on proliferation and antibody synthesis. Eur J Immunol (1973) 1.62
IgM-producing tumors in the BALB-c mouse: a model for B-cell maturation. J Exp Med (1974) 1.61
Differentiation of B cells: sequential appearance of responsiveness to polyclonal activators. Scand J Immunol (1974) 1.57
Occurrence of living adult Wuchereria bancrofti in the scrotal area of men with microfilaraemia. Trans R Soc Trop Med Hyg (1996) 1.56
Cloning of murine transformed cell lines in suspension culture with efficiencies near 100%. Exp Cell Res (1978) 1.55
A novel cell surface molecule on early B-lineage cells. Nature (1986) 1.55
Immunobiology of murine T. cruzi infection: the predominance of parasite-nonspecific responses and the activation of TCRI T cells. Immunol Rev (1989) 1.53
Thymic epithelium tolerizes for histocompatibility antigens. Science (1990) 1.53
The switch from IgM to IgG secretion in single mitogen-stimulated B-cell clones. J Exp Med (1978) 1.52
Evidence for a thymus-dependent form of tolerance that is not based on elimination or anergy of reactive T cells. Immunol Rev (1996) 1.50
'What if they ask how I got it?' Dilemmas of disclosing parental HIV status and testing children for HIV in Uganda. Health Policy Plan (2008) 1.50
Spleen cells from animals tolerant to a thymus-dependent antigen can be activated by lipopolysaccharide to synthesize antibodies against the tolerogen. J Exp Med (1976) 1.48
Polyclonal lymphocyte responses to murine Trypanosoma cruzi infection. I. Quantitation of both T- and B-cell responses. Scand J Immunol (1986) 1.46
Are lymphocytes concerned with our definition of idiotypes? Immunol Today (1993) 1.44
Continuous growth of mitogen-reactive B lymphocytes. Scand J Immunol (1975) 1.43
Self-reactive antibodies (natural autoantibodies) in healthy individuals. J Immunol Methods (1998) 1.41
IgM antibodies induce the production of antibodies of the same specificity. Proc Natl Acad Sci U S A (1980) 1.40
Immunoglobulin C-gene expression. I. The commitment to IgG subclass of secretory cells is determined by the quality of the nonspecific stimuli. Eur J Immunol (1980) 1.39
Xid-associated resistance to experimental Chagas' disease is IFN-gamma dependent. J Immunol (1993) 1.38
Effects of anti-Ia serum on mitogenic responses. I. Inhibition of the proliferative response to B cell mitogen, LPS, by specific anti-Ia sera. J Immunol (1975) 1.36
A retinoic acid receptor alpha antagonist selectively counteracts retinoic acid effects. Proc Natl Acad Sci U S A (1992) 1.36
The repertoire of serum IgM in normal mice is largely independent of external antigenic contact. Eur J Immunol (1997) 1.32
In vitro induction of specific immune responses in the absence of serum: requirement for nonspecific T or B cell mitogens. Eur J Immunol (1973) 1.32
Suppression of polyclonal antibody production in Trypanosoma cruzi-infected mice by treatment with anti-L3T4 antibodies. J Immunol (1987) 1.31
Role of C'3 and Fc receptors in B-lymphocyte activation. J Exp Med (1975) 1.30
Autonomous activation of B and T cells in antigen-free mice. Eur J Immunol (1986) 1.29
Mitogen-activated B-cell blasts reactive to more than one mitogen. J Exp Med (1979) 1.28
Heterogeneity of B cells: direct evidence of selective triggering of distinct subpopulations by polyclonal activators. Scand J Immunol (1976) 1.27
Parasitic load increases and myocardial inflammation decreases in Trypanosoma cruzi-infected mice after inactivation of helper T cells. Ann Inst Pasteur Immunol (1988) 1.27
Mitogenic properties of the thymus-independent antigen pneumococcal polysaccharide S3. Eur J Immunol (1973) 1.26
Ultrasonographic assessment of the adulticidal efficacy of repeat high-dose ivermectin in bancroftian filariasis. Trop Med Int Health (1996) 1.26
Switch in immunoglobulin class production observed in single clones of committed lymphocytes. Science (1978) 1.25
Reactions among IgM antibodies derived from normal, neonatal mice. Eur J Immunol (1984) 1.24
Persistence of polyclonal B cell activation with undetectable parasitemia in late stages of experimental Chagas' disease. J Immunol (1986) 1.24
Administration to mouse of endotoxin from gram-negative bacteria leads to activation and apoptosis of T lymphocytes. Eur J Immunol (1998) 1.23
Genetical control of B-cell responses. III. Requirement for functional mitogenicity of the antigen in thymus-independent specific responses. J Exp Med (1975) 1.23
Genetic and functional characterization of an antiserum to the lipid A-specific triggering receptor on murine B lymphocytes. Eur J Immunol (1978) 1.23
Antibody repertoires of normal BALB/c mice: B lymphocyte populations defined by state of activation. Immunol Rev (1986) 1.22
Population dynamics of B lymphocytes and their precursors: demonstration of high turnover in the central and peripheral lymphoid organs. J Immunol (1982) 1.21
The theory of the 'one nonspecific signal' model for b cell activation. Transplant Rev (1975) 1.21
Functional consequences of sheep red blood cell rosetting for human T cells: gain of reactivity to mitogenic factors. Eur J Immunol (1978) 1.20
Interferon-gamma, mitomycin C, and cycloheximide as regulatory agents of MHC class II-associated invariant chain expression. J Immunol (1986) 1.20
Renal abnormalities in microfilaremic patients with Bancroftian filariasis. Am J Trop Med Hyg (1992) 1.20
An antiserum which recognizes lipopolysaccharide-reactive B cells in the mouse. Eur J Immunol (1978) 1.19
Genetical control of B-cell responses. IV. Inheritance of the unresponsiveness to lipopolysaccharides. J Exp Med (1975) 1.19
B-cell growth factor: distinction from T-cell growth factor and B-cell maturation factor. Proc Natl Acad Sci U S A (1982) 1.19
Derivation of hybrids between a thymoma line and spleen cells activated in a mixed leukocyte reaction. Eur J Immunol (1977) 1.19
Invariance and restriction toward a limited set of self-antigens characterize neonatal IgM antibody repertoires and prevail in autoreactive repertoires of healthy adults. Proc Natl Acad Sci U S A (1995) 1.18
Regulation of T cell growth factor production: arrest of TCGF production after 18 hours in normal lectin-stimulated mouse spleen cell cultures. J Immunol (1981) 1.18
Global analysis of antibody repertoires. II. Evidence for specificity, self-selection and the immunological "homunculus" of antibodies in normal serum. Eur J Immunol (1993) 1.16
Xid immunodeficiency imparts increased parasite clearance and resistance to pathology in experimental Chagas' disease. Int Immunol (1991) 1.16
Lymphocytes selected in allogeneic thymic epithelium mediate dominant tolerance toward tissue grafts of the thymic epithelium haplotype. Proc Natl Acad Sci U S A (1995) 1.15
A model for developmentally acquired thymus-dependent tolerance to central and peripheral antigens. Immunol Rev (1996) 1.15
Isotypic pattern of the polyclonal B cell response during primary infection by Plasmodium chabaudi and in immune-protected mice. Eur J Immunol (1987) 1.15
A suggested mechanism for T lymphocyte activation: implications on the acquisition of functional reactivities. Immunol Rev (1980) 1.15