Published in Ciba Found Symp on January 01, 1986
Identification of the domains in cyclin A required for binding to, and activation of, p34cdc2 and p32cdk2 protein kinase subunits. Mol Biol Cell (1992) 1.85
Destruction of Xenopus cyclins A and B2, but not B1, requires binding to p34cdc2. EMBO J (1994) 1.59
A safeguard eliminates T cell receptor gene-modified autoreactive T cells after adoptive transfer. Proc Natl Acad Sci U S A (2008) 1.06
Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product. Mol Cell Biol (1985) 25.52
Induction of apoptosis in fibroblasts by c-myc protein. Cell (1992) 16.95
The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant. Nat Cell Biol (2000) 9.87
A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins. Nucleic Acids Res (1995) 7.95
Cooperative interaction between c-myc and bcl-2 proto-oncogenes. Nature (1992) 5.50
A matter of life and cell death. Science (1998) 5.33
Virus-specific cytotoxic T-lymphocyte responses select for amino-acid variation in simian immunodeficiency virus Env and Nef. Nat Med (1999) 4.93
The pathological response to DNA damage does not contribute to p53-mediated tumour suppression. Nature (2006) 4.57
Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion. Mol Cell (1999) 4.38
Oncogenic activity of the c-Myc protein requires dimerization with Max. Cell (1993) 4.10
Characterization of the peptide binding motif of a rhesus MHC class I molecule (Mamu-A*01) that binds an immunodominant CTL epitope from simian immunodeficiency virus. J Immunol (1998) 3.65
An analysis of the biological properties of monoclonal antibodies against glycoprotein D of herpes simplex virus and identification of amino acid substitutions that confer resistance to neutralization. J Gen Virol (1986) 3.63
c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines. EMBO J (1994) 3.58
Induction of apoptosis by the Bcl-2 homologue Bak. Nature (1995) 3.56
Interaction between the origin recognition complex and the replication licensing system in Xenopus. Cell (1996) 3.45
Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max. Nature (1992) 3.43
Structural basis for the interaction between FxFG nucleoporin repeats and importin-beta in nuclear trafficking. Cell (2000) 3.33
The protein encoded by the human proto-oncogene c-myc. Proc Natl Acad Sci U S A (1984) 3.31
Restricted expression of EBV latent genes and T-lymphocyte-detected membrane antigen in Burkitt's lymphoma cells. EMBO J (1986) 3.07
Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak. J Cell Biol (1997) 3.03
Subcellular localization of proteins encoded by oncogenes of avian myeloblastosis virus and avian leukemia virus E26 and by chicken c-myb gene. Cell (1984) 2.98
Genetic influences on F cells and other hematologic variables: a twin heritability study. Blood (2000) 2.95
Studies on the interaction of the human c-myc protein with cell nuclei: p62c-myc as a member of a discrete subset of nuclear proteins. Cell (1985) 2.95
Apoptosis as a mechanism of cell death in cultured T lymphoblasts acutely infected with HIV-1. J Clin Invest (1991) 2.82
Caenorhabditis elegans inhibitor of apoptosis protein (IAP) homologue BIR-1 plays a conserved role in cytokinesis. Curr Biol (1999) 2.65
The c-Myc protein induces cell cycle progression and apoptosis through dimerization with Max. EMBO J (1993) 2.57
Identification and preliminary characterization of a protein motif related to the zinc finger. Proc Natl Acad Sci U S A (1993) 2.55
Requirement for the CD95 receptor-ligand pathway in c-Myc-induced apoptosis. Science (1997) 2.52
Isolation of monoclonal antibodies specific for products of avian oncogene myb. Mol Cell Biol (1984) 2.50
The Drosophila caspase DRONC is regulated by DIAP1. EMBO J (2000) 2.46
c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release. Genes Dev (1999) 2.31
Site-specific modulation of c-Myc cotransformation by residues phosphorylated in vivo. Oncogene (1994) 2.05
Apoptosis of human vascular smooth muscle cells derived from normal vessels and coronary atherosclerotic plaques. J Clin Invest (1995) 2.02
A monoclonal anti-HLA antibody recognizes a mouse tumor-associated antigen. Eur J Immunol (1983) 1.97
Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease. Proc Natl Acad Sci U S A (2000) 1.97
Oncogenes and cell death. Curr Opin Genet Dev (1994) 1.97
Human immunodeficiency virus infection of human brain capillary endothelial cells occurs via a CD4/galactosylceramide-independent mechanism. Proc Natl Acad Sci U S A (1993) 1.73
Max and c-Myc/Max DNA-binding activities in cell extracts. Oncogene (1992) 1.73
c-myc protein expression in untransformed fibroblasts. Oncogene (1991) 1.72
Action of Myc in vivo - proliferation and apoptosis. Curr Opin Genet Dev (2000) 1.69
Rhesus macaques that become systemically infected with pathogenic SHIV 89.6-PD after intravenous, rectal, or vaginal inoculation and fail to make an antiviral antibody response rapidly develop AIDS. J Acquir Immune Defic Syndr Hum Retrovirol (1998) 1.64
Identification of a Drosophila melanogaster ICE/CED-3-related protease, drICE. EMBO J (1997) 1.61
Location of amino acid alterations in mutants of aspartate transcarbamoylase: Structural aspects of interallelic complementation. Proc Natl Acad Sci U S A (1984) 1.56
Characterization of primary isolate-like variants of simian-human immunodeficiency virus. J Virol (1999) 1.55
Determinants of disease in the simian immunodeficiency virus-infected rhesus macaque: characterizing animals with low antibody responses and rapid progression. J Gen Virol (1998) 1.51
Caspase-8 in apoptosis: the beginning of "the end"? IUBMB Life (2000) 1.50
Transcription factors 2: helix-loop-helix. Protein Profile (1995) 1.48
drICE is an essential caspase required for apoptotic activity in Drosophila cells. EMBO J (1997) 1.46
Characterization and sequence analyses of antibody-selected antigenic variants of herpes simplex virus show a conformationally complex epitope on glycoprotein H. J Virol (1991) 1.44
Paraproteinaemia after allo-SCT, association with alemtuzumab-based conditioning and CMV reactivation. Bone Marrow Transplant (2010) 1.38
High-density single nucleotide polymorphism array analysis and ASXL1 gene mutation screening in chronic myeloid leukemia during disease progression. Leukemia (2010) 1.38
Domains of human c-myc protein required for autosuppression and cooperation with ras oncogenes are overlapping. Mol Cell Biol (1990) 1.38
Genes encoding Escherichia coli aspartate transcarbamoylase: the pyrB-pyrI operon. Proc Natl Acad Sci U S A (1982) 1.37
In vitro stimulation with a non-peptidic alkylphosphate expands cells expressing Vgamma2-Jgamma1.2/Vdelta2 T-cell receptors. Immunology (2001) 1.36
CD4+-T-cell and CD20+-B-cell changes predict rapid disease progression after simian-human immunodeficiency virus infection in macaques. J Virol (1998) 1.36
Xenopus myc proto-oncogene during development: expression as a stable maternal mRNA uncoupled from cell division. EMBO J (1986) 1.35
Rapid and slow progressors differ by a single MHC class I haplotype in a family of MHC-defined rhesus macaques infected with SIV. Immunol Lett (1999) 1.34
A sensitive and quantitative enzyme-linked immunosorbence assay for the c-myc and N-myc oncoproteins. Oncogene Res (1987) 1.33
Utility of SHIV for testing HIV-1 vaccine candidates in macaques. J Acquir Immune Defic Syndr Hum Retrovirol (1996) 1.32
CED-4 induces chromatin condensation in Schizosaccharomyces pombe and is inhibited by direct physical association with CED-9. Curr Biol (1997) 1.30
Molecular mechanism of translocation through nuclear pore complexes during nuclear protein import. FEBS Lett (2001) 1.27
Intrarectal transmission of simian immunodeficiency virus in rhesus macaques: selective amplification and host responses to transient or persistent viremia. J Virol (1996) 1.24
Identification of domains of the insulin-like growth factor I receptor that are required for protection from apoptosis. Mol Cell Biol (1997) 1.24
Blood-brain barrier disruption in simian immunodeficiency virus encephalitis. Neuropathol Appl Neurobiol (2000) 1.22
A simultaneous flow cytometric assay for c-myc oncoprotein and DNA in nuclei from paraffin embedded material. J Immunol Methods (1985) 1.21
Traps to catch unwary oncogenes. Trends Genet (1998) 1.19
Gamma delta T lymphocyte responses to HIV. Clin Exp Immunol (1996) 1.17
Omomyc expression in skin prevents Myc-induced papillomatosis. Cell Death Differ (2004) 1.16
Methods for detecting and quantifying apoptosis. Curr Top Dev Biol (1998) 1.16
Functional gamma delta T-lymphocyte defect associated with human immunodeficiency virus infections. Mol Med (1997) 1.16
Delay of vaccinia virus-induced apoptosis in nonpermissive Chinese hamster ovary cells by the cowpox virus CHOhr and adenovirus E1B 19K genes. J Virol (1995) 1.16
Selective amplification of simian immunodeficiency virus genotypes after intrarectal inoculation of rhesus monkeys. J Virol (1994) 1.16
Inhibition of vascular smooth muscle cell proliferation in vitro and in vivo by c-myc antisense oligodeoxynucleotides. J Clin Invest (1994) 1.14
Transcription factors 2: helix-loop-helix. Protein Profile (1994) 1.13
Elevated expression of the c-myc oncoprotein correlates with poor prognosis in head and neck squamous cell carcinoma. Oncogene (1989) 1.11
Monomeric solution structure of the prototypical 'C' chemokine lymphotactin. Biochemistry (2001) 1.11
The level of haemoglobin in anaemic cancer patients correlates positively with quality of life. Br J Cancer (2002) 1.09
Identification and characterisation of the egr-1 gene product as an inducible, short-lived, nuclear phosphoprotein. Oncogene (1990) 1.08
Resistance to p53-mediated growth arrest and apoptosis in Hep 3B hepatoma cells. Oncogene (1997) 1.06
Induced differentiation of avian myeloblastosis virus-transformed myeloblasts: phenotypic alteration without altered expression of the viral oncogene. Mol Cell Biol (1984) 1.06
Induction of TNF-sensitive cellular phenotype by c-Myc involves p53 and impaired NF-kappaB activation. EMBO J (1997) 1.05
Flow cytometric quantitation of DNA and c-myc oncoprotein in archival biopsies of uterine cervix neoplasia. Br J Cancer (1987) 1.05
Adult acute lymphoblastic leukaemia presenting with bone marrow aplasia. Clin Lab Haematol (1986) 1.03
Changing patterns of c-fos induction in spinal neurons following thermal cutaneous stimulation in the rat. Neuroscience (1990) 1.03
Cyclophilin a modulates processing of human immunodeficiency virus type 1 p55Gag: mechanism for antiviral effects of cyclosporin A. Virology (1998) 1.02
The clinical significance of flow cytometric c-myc oncoprotein quantitation in testicular cancer. Br J Cancer (1986) 1.01
Human Vgamma2Vdelta2 T cells contain cytoplasmic RANTES. Int Immunol (2006) 1.00
Cellular immune responses in rhesus macaques infected rectally with low dose simian immunodeficiency virus. J Med Primatol (1994) 0.98
Apoptosis. Breaking the ICE. Curr Biol (1994) 0.98
Characterization of a heat shock-induced insoluble complex in the nuclei of cells. J Cell Sci (1987) 0.95
Intestinal barrier to large particulates in mice. J Toxicol Environ Health (1980) 0.95