Published in J Biol Chem on July 25, 1987
Characterization of the hepatitis C virus-encoded serine proteinase: determination of proteinase-dependent polyprotein cleavage sites. J Virol (1993) 6.36
BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth. J Exp Med (1999) 6.27
Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli. Proc Natl Acad Sci U S A (1988) 6.14
Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro. J Virol (1992) 6.07
Ubiquitin-conjugating enzymes UBC4 and UBC5 mediate selective degradation of short-lived and abnormal proteins. EMBO J (1990) 5.31
Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor. Proc Natl Acad Sci U S A (1992) 5.28
Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme. EMBO J (1992) 5.23
Major cold shock protein of Escherichia coli. Proc Natl Acad Sci U S A (1990) 4.90
A conserved family of nuclear phosphoproteins localized to sites of polymerase II transcription. J Cell Biol (1991) 4.80
A major surface protein on group A streptococci is a glyceraldehyde-3-phosphate-dehydrogenase with multiple binding activity. J Exp Med (1992) 4.60
Identifying proteins from two-dimensional gels by molecular mass searching of peptide fragments in protein sequence databases. Proc Natl Acad Sci U S A (1993) 4.58
Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease. Proc Natl Acad Sci U S A (1988) 4.45
Low-passage-associated proteins of Borrelia burgdorferi B31: characterization and molecular cloning of OspD, a surface-exposed, plasmid-encoded lipoprotein. Infect Immun (1992) 4.42
Molecular characterization of the Clostridium difficile toxin A gene. Infect Immun (1990) 4.06
Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity. EMBO J (1992) 3.98
Vascular permeability factor: a tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration. J Exp Med (1990) 3.93
Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing. Proc Natl Acad Sci U S A (1994) 3.85
Sequence analysis of PER-1 extended-spectrum beta-lactamase from Pseudomonas aeruginosa and comparison with class A beta-lactamases. Antimicrob Agents Chemother (1994) 3.82
FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family. EMBO J (2000) 3.81
Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity. J Exp Med (1998) 3.72
Receptor for mouse hepatitis virus is a member of the carcinoembryonic antigen family of glycoproteins. Proc Natl Acad Sci U S A (1991) 3.70
CPF1, a yeast protein which functions in centromeres and promoters. EMBO J (1990) 3.65
Processing in the hepatitis C virus E2-NS2 region: identification of p7 and two distinct E2-specific products with different C termini. J Virol (1994) 3.61
In vitro processing of dengue virus type 2 nonstructural proteins NS2A, NS2B, and NS3. J Virol (1990) 3.50
Anti-neutrophil cytoplasm antibodies in Wegener's granulomatosis recognize an elastinolytic enzyme. J Exp Med (1990) 3.37
Expression of separate isoforms of human tau protein: correlation with the tau pattern in brain and effects on tubulin polymerization. EMBO J (1990) 3.36
Long-circulating bacteriophage as antibacterial agents. Proc Natl Acad Sci U S A (1996) 3.34
Pathogen-induced proteins with inhibitory activity toward Phytophthora infestans. Plant Cell (1991) 3.28
Isolation of the gene encoding the Saccharomyces cerevisiae centromere-binding protein CP1. Mol Cell Biol (1990) 3.24
RNA polymerase II subunit RPB4 is essential for high- and low-temperature yeast cell growth. Mol Cell Biol (1989) 3.21
The HtrA (DegP) protein, essential for Escherichia coli survival at high temperatures, is an endopeptidase. J Bacteriol (1990) 3.14
Sequence of the gene coding for ammonia monooxygenase in Nitrosomonas europaea. J Bacteriol (1993) 3.07
Dimer formation drives the activation of the cell death protease caspase 9. Proc Natl Acad Sci U S A (2001) 3.04
Cloning and characterization of a Pseudomonas mendocina KR1 gene cluster encoding toluene-4-monooxygenase. J Bacteriol (1991) 3.01
Determinants for glycophospholipid anchoring of the Saccharomyces cerevisiae GAS1 protein to the plasma membrane. Mol Cell Biol (1991) 2.96
Intervening sequences in an Archaea DNA polymerase gene. Proc Natl Acad Sci U S A (1992) 2.92
A novel integrin (alpha E beta 4) from human epithelial cells suggests a fourth family of integrin adhesion receptors. EMBO J (1989) 2.87
CheA protein, a central regulator of bacterial chemotaxis, belongs to a family of proteins that control gene expression in response to changing environmental conditions. Proc Natl Acad Sci U S A (1988) 2.85
Phenotypic modulation by Legionella pneumophila upon infection of macrophages. Infect Immun (1993) 2.79
Identification of a monocyte specific pre-interleukin 1 beta convertase activity. Proc Natl Acad Sci U S A (1989) 2.73
Primary structure and cellular localization of chicken brain myosin-V (p190), an unconventional myosin with calmodulin light chains. J Cell Biol (1992) 2.73
Human lamin B contains a farnesylated cysteine residue. J Biol Chem (1989) 2.71
Role of vacuolar acidification in protein sorting and zymogen activation: a genetic analysis of the yeast vacuolar proton-translocating ATPase. Mol Cell Biol (1990) 2.69
Polypeptides of Treponema pallidum: progress toward understanding their structural, functional, and immunologic roles. Treponema Pallidum Polypeptide Research Group. Microbiol Rev (1993) 2.67
Characterization of a vaccinia virus-encoded 42-kilodalton class I membrane glycoprotein component of the extracellular virus envelope. J Virol (1992) 2.60
Antibiotic proteins of human polymorphonuclear leukocytes. Proc Natl Acad Sci U S A (1989) 2.59
Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells. Proc Natl Acad Sci U S A (1993) 2.57
Cleavage at a novel site in the NS4A region by the yellow fever virus NS2B-3 proteinase is a prerequisite for processing at the downstream 4A/4B signalase site. J Virol (1993) 2.56
Biochemical and immunological characterization of the surface proteins of Borrelia burgdorferi. Infect Immun (1989) 2.56
UmuC mutagenesis protein of Escherichia coli: purification and interaction with UmuD and UmuD'. Proc Natl Acad Sci U S A (1989) 2.52
Aggregative adherence fimbria II, a second fimbrial antigen mediating aggregative adherence in enteroaggregative Escherichia coli. Infect Immun (1997) 2.50
Characterization of a toxin A-negative, toxin B-positive strain of Clostridium difficile. Infect Immun (1992) 2.49
Propeptide of a precursor to a plant vacuolar protein required for vacuolar targeting. Proc Natl Acad Sci U S A (1991) 2.48
A third secreted protein that is encoded by the enteropathogenic Escherichia coli pathogenicity island is required for transduction of signals and for attaching and effacing activities in host cells. Infect Immun (1997) 2.40
Cryptdins: antimicrobial defensins of the murine small intestine. Infect Immun (1992) 2.39
EndoS, a novel secreted protein from Streptococcus pyogenes with endoglycosidase activity on human IgG. EMBO J (2001) 2.38
Molecular cloning, structure and expression of the yeast proliferating cell nuclear antigen gene. Nucleic Acids Res (1990) 2.38
The PapG adhesin of uropathogenic Escherichia coli contains separate regions for receptor binding and for the incorporation into the pilus. Proc Natl Acad Sci U S A (1989) 2.36
Molecular characterization and expression of p23 (OspC) from a North American strain of Borrelia burgdorferi. Infect Immun (1993) 2.36
Drosophila male-specific lethal-2 protein: structure/function analysis and dependence on MSL-1 for chromosome association. Genetics (1997) 2.35
Product of the Pseudomonas aeruginosa gene pilD is a prepilin leader peptidase. Proc Natl Acad Sci U S A (1991) 2.34
The human integrin VLA-2 is a collagen receptor on some cells and a collagen/laminin receptor on others. Proc Natl Acad Sci U S A (1989) 2.31
A single bifunctional enzyme, PilD, catalyzes cleavage and N-methylation of proteins belonging to the type IV pilin family. Proc Natl Acad Sci U S A (1993) 2.31
Processing of the mother-cell sigma factor, sigma K, may depend on events occurring in the forespore during Bacillus subtilis development. Proc Natl Acad Sci U S A (1990) 2.31
Cloning of the gene encoding the yeast protein BTF1Y, which can substitute for the human TATA box-binding factor. Proc Natl Acad Sci U S A (1989) 2.30
A carboxy-terminal fragment of protein mu 1/mu 1C is present in infectious subvirion particles of mammalian reoviruses and is proposed to have a role in penetration. J Virol (1992) 2.29
The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein. EMBO J (1996) 2.28
Combined transcriptome and proteome analysis as a powerful approach to study genes under glucose repression in Bacillus subtilis. Nucleic Acids Res (2001) 2.28
An essential Saccharomyces cerevisiae single-stranded DNA binding protein is homologous to the large subunit of human RP-A. EMBO J (1990) 2.28
The papain-like protease from the severe acute respiratory syndrome coronavirus is a deubiquitinating enzyme. J Virol (2005) 2.27
Characterization of motifs which are critical for activity of the cyclic AMP-responsive transcription factor CREB. Mol Cell Biol (1991) 2.27
Tissue cooperation in a proteolytic cascade activating human interstitial collagenase. Proc Natl Acad Sci U S A (1989) 2.26
Role of fimbriae expressed by nontypeable Haemophilus influenzae in pathogenesis of and protection against otitis media and relatedness of the fimbrin subunit to outer membrane protein A. Infect Immun (1994) 2.25
Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions. J Exp Med (1992) 2.25
The regulatory VirG protein specifically binds to a cis-acting regulatory sequence involved in transcriptional activation of Agrobacterium tumefaciens virulence genes. J Bacteriol (1990) 2.24
Human myeloid plasma membrane glycoprotein CD13 (gp150) is identical to aminopeptidase N. J Clin Invest (1989) 2.23
Identification of a cleavage site directing the immunochemical detection of molecular abnormalities in type IIA von Willebrand factor. Proc Natl Acad Sci U S A (1990) 2.23
Decorin-binding protein of Borrelia burgdorferi is encoded within a two-gene operon and is protective in the murine model of Lyme borreliosis. Infect Immun (1998) 2.23
Identification of the gene for an Escherichia coli poly(A) polymerase. Proc Natl Acad Sci U S A (1992) 2.22
Primary structure and unique expression of the 22-kilodalton light chain of human neutrophil cytochrome b. Proc Natl Acad Sci U S A (1988) 2.21
The immunoregulatory mediator macrophage migration inhibitory factor (MIF) catalyzes a tautomerization reaction. Mol Med (1996) 2.21
UBA 1: an essential yeast gene encoding ubiquitin-activating enzyme. EMBO J (1991) 2.20
Identification of cyclophilin as a proinflammatory secretory product of lipopolysaccharide-activated macrophages. Proc Natl Acad Sci U S A (1992) 2.20
Immunohistochemical detection and immunochemical analysis of type II collagen degradation in human normal, rheumatoid, and osteoarthritic articular cartilages and in explants of bovine articular cartilage cultured with interleukin 1. J Clin Invest (1989) 2.20
Isolation and structural characterization of a cDNA clone encoding the human DNA repair protein for O6-alkylguanine. Proc Natl Acad Sci U S A (1990) 2.19
Regulation of the Bacillus subtilis pyrimidine biosynthetic (pyr) gene cluster by an autogenous transcriptional attenuation mechanism. J Bacteriol (1994) 2.17
Structure and probable genetic location of a "ribosome modulation factor" associated with 100S ribosomes in stationary-phase Escherichia coli cells. Proc Natl Acad Sci U S A (1990) 2.14
Molecular analysis of the 60-kDa human Ro ribonucleoprotein. Proc Natl Acad Sci U S A (1988) 2.11
NS2B-3 proteinase-mediated processing in the yellow fever virus structural region: in vitro and in vivo studies. J Virol (1994) 2.11
A gene cluster involved in the utilization of both free heme and heme:hemopexin by Haemophilus influenzae type b. J Bacteriol (1995) 2.08
Purification and characterization of cytosolic aconitase from beef liver and its relationship to the iron-responsive element binding protein. Proc Natl Acad Sci U S A (1992) 2.06
Fimbrin is a homologue of the cytoplasmic phosphoprotein plastin and has domains homologous with calmodulin and actin gelation proteins. J Cell Biol (1990) 2.06
Sequence of a cysteine-rich galactose-specific lectin of Entamoeba histolytica. Proc Natl Acad Sci U S A (1991) 2.03
A family of beta 7 integrins on human mucosal lymphocytes. Proc Natl Acad Sci U S A (1992) 2.03
The primary structure of the VLA-2/collagen receptor alpha 2 subunit (platelet GPIa): homology to other integrins and the presence of a possible collagen-binding domain. J Cell Biol (1989) 2.02
Bovine viral diarrhea virus NS3 serine proteinase: polyprotein cleavage sites, cofactor requirements, and molecular model of an enzyme essential for pestivirus replication. J Virol (1997) 2.00
Secretion, localization, and antibacterial activity of TasA, a Bacillus subtilis spore-associated protein. J Bacteriol (1999) 1.99
Expression of human plasma gelsolin in Escherichia coli and dissection of actin binding sites by segmental deletion mutagenesis. J Cell Biol (1989) 1.97
Ankyrin-binding proteins related to nervous system cell adhesion molecules: candidates to provide transmembrane and intercellular connections in adult brain. J Cell Biol (1993) 1.96
Elastic behavior of cross-linked and bundled actin networks. Science (2004) 5.44
Type I macrophage scavenger receptor contains alpha-helical and collagen-like coiled coils. Nature (1990) 4.52
F-actin binding and bundling properties of fimbrin, a major cytoskeletal protein of microvillus core filaments. J Biol Chem (1981) 2.72
The major human erythroid DNA-binding protein (GF-1): primary sequence and localization of the gene to the X chromosome. Proc Natl Acad Sci U S A (1990) 2.68
Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells. Proc Natl Acad Sci U S A (1993) 2.57
Limited N-terminal sequence analysis. Methods Enzymol (1990) 2.40
Direct protein microsequencing from Immobilon-P Transfer Membrane. Biotechniques (1988) 2.32
Motility powered by supramolecular springs and ratchets. Science (2000) 2.15
Fimbrin is a homologue of the cytoplasmic phosphoprotein plastin and has domains homologous with calmodulin and actin gelation proteins. J Cell Biol (1990) 2.06
Colloid surface chemistry critically affects multiple particle tracking measurements of biomaterials. Biophys J (2004) 2.02
Relating microstructure to rheology of a bundled and cross-linked F-actin network in vitro. Proc Natl Acad Sci U S A (2004) 1.91
Calmodulin dissociation regulates brush border myosin I (110-kD-calmodulin) mechanochemical activity in vitro. J Cell Biol (1990) 1.81
An atomic model of actin filaments cross-linked by fimbrin and its implications for bundle assembly and function. J Cell Biol (2001) 1.80
Villin sequence and peptide map identify six homologous domains. Proc Natl Acad Sci U S A (1988) 1.71
An atomic model of fimbrin binding to F-actin and its implications for filament crosslinking and regulation. Nat Struct Biol (1998) 1.57
Integrating the actin and vimentin cytoskeletons. adhesion-dependent formation of fimbrin-vimentin complexes in macrophages. J Cell Biol (1999) 1.52
Fascin, an echinoid actin-bundling protein, is a homolog of the Drosophila singed gene product. Proc Natl Acad Sci U S A (1993) 1.49
Three-dimensional structure of a single filament in the Limulus acrosomal bundle: scruin binds to homologous helix-loop-beta motifs in actin. J Cell Biol (1994) 1.47
Epstein-Barr virus infection induces expression in B lymphocytes of a novel gene encoding an evolutionarily conserved 55-kilodalton actin-bundling protein. J Virol (1994) 1.45
Inhibition of energy metabolism alters the processing of amyloid precursor protein and induces a potentially amyloidogenic derivative. J Biol Chem (1994) 1.40
Power-limited contraction dynamics of Vorticella convallaria: an ultrafast biological spring. Biophys J (2007) 1.38
Role of fimbrin and villin in determining the interfilament distances of actin bundles. Nature (1983) 1.31
Identification of I-plastin, a human fimbrin isoform expressed in intestine and kidney. Mol Cell Biol (1994) 1.30
Cysteine scanning mutagenesis at 40 of 76 positions in villin headpiece maps the F-actin binding site and structural features of the domain. Biochemistry (1996) 1.30
The structure of an actin-crosslinking domain from human fimbrin. Nat Struct Biol (1997) 1.29
Evidence for a conformational change in actin induced by fimbrin (N375) binding. J Cell Biol (1997) 1.27
Sequence and domain organization of scruin, an actin-cross-linking protein in the acrosomal process of Limulus sperm. J Cell Biol (1995) 1.21
Brush border myosin-I truncated in the motor domain impairs the distribution and the function of endocytic compartments in an hepatoma cell line. Proc Natl Acad Sci U S A (1996) 1.19
Fimbrin localized to an insoluble cytoskeletal fraction is constitutively phosphorylated on its headpiece domain in adherent macrophages. Cell Motil Cytoskeleton (1993) 1.17
Crystallographic analysis of acrosomal bundle from Limulus sperm. J Mol Biol (1991) 1.16
Fimbrin in podosomes of monocyte-derived osteoclasts. Cell Motil Cytoskeleton (1997) 1.13
Mapping the cysteine residues and actin-binding regions of villin by using antisera to the amino and carboxyl termini of the molecule. Proc Natl Acad Sci U S A (1985) 1.09
Modification of Cys-837 identifies an actin-binding site in the beta-propeller protein scruin. Mol Biol Cell (1997) 1.07
The three-dimensional structure of the Limulus acrosomal process: a dynamic actin bundle. J Mol Biol (1999) 1.07
Characterization of the actin cross-linking properties of the scruin-calmodulin complex from the acrosomal process of Limulus sperm. J Biol Chem (1996) 1.07
Laser-guided assembly of heterotypic three-dimensional living cell microarrays. Biophys J (2006) 1.05
A gelsolin-like Ca2+-dependent actin-binding domain in villin. Nature (1985) 1.04
Eight hundred-base sequencing in a microfabricated electrophoretic device. Anal Chem (2000) 1.03
Biochemical evidence that a D-loop is part of a four-stranded PNA-DNA bundle. Nickel-mediated cleavage of duplex DNA by a Gly-Gly-His bis-PNA. Biochemistry (1996) 1.03
DNA sequencing on microfabricated electrophoretic devices. Anal Chem (1998) 0.99
Microchip electrophoresis: a method for high-speed SNP detection. Nucleic Acids Res (2000) 0.99
Isoform-specific complementation of the yeast sac6 null mutation by human fimbrin. Mol Cell Biol (1995) 0.99
Imaging frozen, hydrated acrosomal bundle from Limulus sperm at 7 A resolution with a 400 kV electron cryomicroscope. J Mol Biol (1993) 0.98
Effects of radiation damage with 400-kV electrons on frozen, hydrated actin bundles. J Struct Biol (1992) 0.95
beta-Scruin, a homologue of the actin crosslinking protein scruin, is localized to the acrosomal vesicle of Limulus sperm. J Cell Sci (1995) 0.94
Solution structure of villin 14T, a domain conserved among actin-severing proteins. Protein Sci (1994) 0.93
DNA typing in thirty seconds with a microfabricated device. Proc Natl Acad Sci U S A (1997) 0.91
Refined structure of villin 14T and a detailed comparison with other actin-severing domains. Protein Sci (1997) 0.91
A closed-cycle capillary polymerase chain reaction machine. Anal Chem (2001) 0.89
An actin footprint on villin. Single site substitutions in a cluster of basic residues inhibit the actin severing but not capping activity of villin. J Biol Chem (1992) 0.89
Effect of deuteration on the amide proton relaxation rates in proteins. Heteronuclear NMR experiments on villin 14T. J Magn Reson B (1994) 0.89
Synchrotron x-ray diffraction studies of actin structure during polymerization. Proc Natl Acad Sci U S A (1987) 0.89
Sequential expression and differential localization of I-, L-, and T-fimbrin during differentiation of the mouse intestine and yolk sac. Dev Dyn (1995) 0.85
Differential regulation of vertebrate myosins I and II. J Cell Sci Suppl (1991) 0.85
Optimization of high-performance DNA sequencing on short microfabricated electrophoretic devices. Anal Chem (2000) 0.84
Scaling structure factor amplitudes in electron cryomicroscopy using X-Ray solution scattering. J Struct Biol (1999) 0.84
Local mobility within villin 14T probed via heteronuclear relaxation measurements and a reduced spectral density mapping. Biochemistry (1996) 0.84
Toward real-world sequencing by microdevice electrophoresis. Genome Res (1999) 0.83
Microfluidic devices for DNA analysis. Trends Biotechnol (1999) 0.82
Recent developments in DNA sequencing by capillary and microdevice electrophoresis. Electrophoresis (1999) 0.81
Two-color multiplexed analysis of eight short tandem repeat loci with an electrophoretic microdevice. Anal Biochem (1999) 0.81
Calcium regulation of an actin spring. Biophys J (2009) 0.80
Crystallization and preliminary crystallographic analysis of the N-terminal actin binding domain of human fimbrin. Proteins (1997) 0.78
The secrets of severing? Curr Biol (1993) 0.77
Brush border myosin I (BBMI): a basally localized transcript in human jejunal enterocytes. J Histochem Cytochem (2000) 0.77
1H, 15N, 13C and 13CO resonance assignments and secondary structure of villin 14T, a domain conserved among actin-severing proteins. J Biomol NMR (1994) 0.77
Cloning and sequencing of the Leishmania major actin-encoding gene. Gene (1994) 0.77
A 7-A projection map of frozen, hydrated acrosomal bundle from Limulus sperm. J Struct Biol (1995) 0.76
Antibodies to T- and L-isoforms of the cytoskeletal protein, fimbrin, in patients with systemic lupus erythematosus. J Clin Invest (1992) 0.75
Three-dimensional structure of the acrosomal filament of Limulus sperm by 400 kV electron cryomicroscopy. Biophys J (1995) 0.75
Myosin I: a new insight into the mechanism and cellular significance of actin-based motility. Adv Biophys (1991) 0.75
A strategy for electron tomographic data collection and crystallographic reconstruction of biological bundles. J Struct Biol (1997) 0.75
Shear-induced degradation of linear polyacrylamide solutions during pre-electrophoretic loading. Anal Chem (2001) 0.75
Genotyping by microdevice electrophoresis. Methods Mol Biol (2001) 0.75