Published in Br Med J on October 07, 1978
Study of the prevalence of atrial fibrillation in general practice patients over 65 years of age. J R Coll Gen Pract (1987) 1.92
Rapid nontranscriptional activation of endothelial nitric oxide synthase mediates increased cerebral blood flow and stroke protection by corticosteroids. J Clin Invest (2002) 1.40
High dose steroid treatment in cerebral infarction. Br Med J (Clin Res Ed) (1986) 1.11
Therapeutic interventions in acute stroke. Br J Clin Pharmacol (1992) 1.10
Clinical trials for cytoprotection in stroke. NeuroRx (2004) 1.08
Avascular necrosis of bone after high doses of dexamethasone during neurosurgery. Br Med J (Clin Res Ed) (1982) 0.99
The effect of isovolaemic haemodilution and intravenous glycerol on the sequelae of middle cerebral artery occlusion in the rat. J Neurol Neurosurg Psychiatry (1986) 0.88
Early diagnosis and treatment of steroid induced avascular necrosis of bone. Br Med J (Clin Res Ed) (1984) 0.75
The diagnostic challenge of acute polyarthritis. Ann Rheum Dis (1996) 0.75
New approach to treatment of recent stroke. Br Med J (1979) 0.75
Dexamethasone as treatment in cerebrovascular disease. 2. A controlled study in acute cerebral infarction. Stroke (1973) 1.34
Double-blind study of the effects of dexamethasone on acute stroke. Neurology (1972) 1.33
Cortisone in immediate therapy of apoplectic stroke. J Am Med Assoc (1955) 1.26
Massive cerebral infarction with severe brain swelling: a clinicopathological study. Stroke (1972) 1.20
Steroid therapy in acute cerebral infarction. Arch Neurol (1976) 1.12
The influence of adrenocortical steroids on severe cerebrovascular accidents. J Nerv Ment Dis (1965) 1.08
Effect of cortisone and hydrocortisone in hemiplegia after cerebral infarction. I. Preliminary report, with special reference to spasticity. J Am Med Assoc (1955) 0.94
Letter: Anti-oedema treatment of completed stroke. Lancet (1974) 0.93
Relative contributions of history-taking, physical examination, and laboratory investigation to diagnosis and management of medical outpatients. Br Med J (1975) 9.18
Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione. J Pharmacol Exp Ther (1973) 5.23
Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism. J Pharmacol Exp Ther (1973) 4.40
Bromobenzene-induced liver necrosis. Protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolite. Pharmacology (1974) 4.32
A randomised trial of home-versus-hospital management for patients with suspected myocardial infarction. Lancet (1978) 4.12
Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo. J Pharmacol Exp Ther (1973) 3.89
Interim discharge summaries: how are they best delivered to general practitioners? Br Med J (Clin Res Ed) (1987) 3.64
Predictors of outcome in patients with acute coronary syndromes without persistent ST-segment elevation. Results from an international trial of 9461 patients. The PURSUIT Investigators. Circulation (2000) 3.61
Menopausal flushing: does oestrogen therapy make sense? Lancet (1976) 3.47
Self-poisoning: management of patients in Nottingham, 1976. Br Med J (1978) 3.24
Acetaminophen-induced hepatic injury: protective role of glutathione in man and rationale for therapy. Clin Pharmacol Ther (1974) 2.62
Aplastic anaemia and hair dye. Br Med J (1976) 2.58
Accumulation and elimination of poliovirus by the eastern oyster. Am J Epidemiol (1966) 2.58
Trial of early nifedipine in acute myocardial infarction: the Trent study. Br Med J (Clin Res Ed) (1986) 2.55
Randomised placebo-controlled trial comparing oxprenolol with disopyramide phosphate in immediate treatment of suspected myocardial infarction. Lancet (1980) 2.53
Isoniazid liver injury: clinical spectrum, pathology, and probable pathogenesis. Ann Intern Med (1976) 2.33
Randomised trial comparing propranolol with atenolol in immediate treatment of suspected myocardial infarction. Br Med J (1980) 2.32
Prognosis of patients with "chest pain ?cause". Br Med J (Clin Res Ed) (1981) 2.32
Verification of smoking history in patients after infarction using urinary nicotine and cotinine measurements. Br Med J (1979) 2.30
Guanethidine and related agents. 3. Antagonism by drugs which inhibit the norepinephrine pump in man. J Clin Invest (1970) 2.29
Geographic variation in patient and hospital characteristics, management, and clinical outcomes in ST-elevation myocardial infarction treated with fibrinolysis. Results from InTIME-II. Eur Heart J (2001) 2.28
RNA binding domain of telomerase reverse transcriptase. Mol Cell Biol (2001) 2.27
Effect of lipid-lowering therapy on early mortality after acute coronary syndromes: an observational study. Lancet (2001) 2.23
Effect of a pyrimidopyrimidine derivative on thrombus formation in the rabbit. Nature (1965) 2.19
Is nursing any business of doctors? A simple guide to the "nursing process". Br Med J (Clin Res Ed) (1984) 2.17
Early reporting of myocardial infarction: impact of an experiment in patient education. Br Med J (Clin Res Ed) (1982) 2.11
Influence of diabetes mellitus on clinical outcome in the thrombolytic era of acute myocardial infarction. GUSTO-I Investigators. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries. J Am Coll Cardiol (1997) 2.08
Plasma cortisol as a measure of stress response in acute stroke. Stroke (1989) 2.04
Isoniazid-associated hepatitis in 114 patients. Gastroenterology (1975) 2.02
Randomised study of six beta-blockers and a thiazide diuretic in essential hypertension. Br Med J (1978) 2.02
Platelet reactivity and serum thromboxane B2 production in whole blood in gestational hypertension and pre-eclampsia. Br J Obstet Gynaecol (1991) 1.91
Acetaminophen-induced hepatic necrosis. 3. Cytochrome P-450-mediated covalent binding in vitro. J Pharmacol Exp Ther (1973) 1.90
Effect of prostaglandin E1 on platelet behaviour in vitro and in vivo. Br Med J (1967) 1.85
Extracts of feverfew inhibit granule secretion in blood platelets and polymorphonuclear leucocytes. Lancet (1985) 1.84
An association between abo blood-group distribution and geographical differences in death-rates. Lancet (1977) 1.81
Effect of dipyridamole on human platelet behaviour. Lancet (1965) 1.79
Plasma glutathione and glutathione disulfide in the rat: regulation and response to oxidative stress. J Pharmacol Exp Ther (1983) 1.79
Increased incidence of isoniazid hepatitis in rapid acetylators: possible relation to hydranize metabolites. Clin Pharmacol Ther (1975) 1.75
Oxidation of alpha-methyldopa and other catechols by cytochrome P-450-generated superoxide anion: possible mechanism of methyldopa hepatitis. Mol Pharmacol (1976) 1.73
Acetaminophen-induced hepatic necrosis. VI. Metabolic disposition of toxic and nontoxic doses of acetaminophen. Pharmacology (1974) 1.70
Is an information booklet for patients leaving hospital helpful and useful? BMJ (1989) 1.68
Antagonism of the antihypertensive action of guanethidine sulfate by desipramine hydrochloride. JAMA (1967) 1.67
What constitutes evidence on the dietary prevention of coronary heart disease? Cosy beliefs or harsh facts? Int J Cardiol (1984) 1.66
Geographic variability in outcomes within an international trial of glycoprotein IIb/IIIa inhibition in patients with acute coronary syndromes. Results from PURSUIT. Eur Heart J (2000) 1.62
Randomised double-blind placebo-controlled trial of feverfew in migraine prevention. Lancet (1988) 1.62
Association of white blood cell count with increased mortality in acute myocardial infarction and unstable angina pectoris. OPUS-TIMI 16 Investigators. Am J Cardiol (2001) 1.60
The role of the interview in student selection. S Afr Med J (1978) 1.59
Autumn Books: Who needs Clinical Pharmacology? Br Med J (Clin Res Ed) (1984) 1.57
"But will it help my patients with myocardial infarction?" The implications of recent trials for everyday country folk. Br Med J (Clin Res Ed) (1982) 1.55
Effect of aggregating agents on the electrophoretic mobility of human platelets. Br Med J (1966) 1.55
Prevention and diagnosis of venous thrombosis in patients with hip fractures. A survey of current practice. Lancet (1976) 1.52
Blood pressure reduction in elderly: a randomised controlled trial of methyldopa. Br Med J (Clin Res Ed) (1981) 1.52
Effect of oestrogens on human platelet behaviour. Lancet (1968) 1.49
Late assessment of thrombolytic efficacy (LATE) study: prognosis in patients with non-Q wave myocardial infarction. (LATE Study Investigators) J Am Coll Cardiol (1996) 1.48
Treating stroke: home or hospital? Br Med J (1978) 1.48
Availability of on-site catheterization and clinical outcomes in patients receiving fibrinolysis for ST-elevation myocardial infarction. Eur Heart J (2001) 1.47
Low dose beta blockade in acute stroke ("BEST" trial): an evaluation. Br Med J (Clin Res Ed) (1988) 1.47
Use of isolated perfused organs in hypoxia and ischemia/reperfusion oxidant stress. Methods Enzymol (1990) 1.46
Patients' and general practitioners' satisfaction with information given on discharge from hospital: audit of a new information card. BMJ (1989) 1.45
Acetaminophen-induced hepatic necrosis. V. Correlation of hepatic necrosis, covalent binding and glutathione depletion in hamsters. Pharmacology (1974) 1.43
Progress in hepatology. Metabolic activation of drugs to toxic substances. Gastroenterology (1975) 1.42
Effect of beta-blockers on arrhythmias during six weeks after suspected myocardial infarction. Br Med J (1979) 1.41
Safety and preliminary efficacy of one month glycoprotein IIb/IIIa inhibition with lefradafiban in patients with acute coronary syndromes without ST-elevation; a phase II study. Eur Heart J (2000) 1.40
Prospective use of glycoprotein IIb/IIIa receptor blockers in the emergency department setting. Ann Emerg Med (1998) 1.39
New atrial fibrillation after acute myocardial infarction independently predicts death: the GUSTO-III experience. Am Heart J (2000) 1.39
Reactive oxygen species during ischemia-reflow injury in isolated perfused rat liver. J Clin Invest (1988) 1.38
Parent and peer attachment in early adolescent depression. J Abnorm Child Psychol (1990) 1.38
Isoniazid and iproniazid: activation of metabolites to toxic intermediates in man and rat. Science (1976) 1.38
Magnetization transfer and multicomponent T2 relaxation measurements with histopathologic correlation in an experimental model of MS. J Magn Reson Imaging (2000) 1.37
Anticoagulants in coronary heart disease--retrospect and prospect. Lancet (1981) 1.36
Platelet behaviour and drugs used in cardiovascular disease. Cardiovasc Res (1967) 1.32
Abnormalities in platelet behaviour in acute illnesses. Br Med J (1966) 1.31
Treatment of high blood pressure: should clinical practice be based on results of clinical trials? Br Med J (Clin Res Ed) (1986) 1.31
Mechanism of action of N-acetylcysteine in the protection against the hepatotoxicity of acetaminophen in rats in vivo. J Clin Invest (1983) 1.31
Nature of the transferable factor which causes abnormal platelet behaviour in vascular disease. Lancet (1967) 1.27
Clinical management of venous thrombo-embolism. Br Med Bull (1978) 1.26
Contribution of atenolol, bendrofluazide, and hydrallazine to management of severe hypertension. Br Med J (1977) 1.26
Organisation of the external region of the starch granule as determined by infrared spectroscopy. Int J Biol Macromol (2002) 1.26
Guanethidine and related agents. I. Mechanism of the selective blockade of adrenergic neurons and its antagonism by drugs. J Pharmacol Exp Ther (1970) 1.26
Timolol after myocardial infarction: an answer or a new set of questions? Br Med J (Clin Res Ed) (1981) 1.25
Platelet aggregation in whole blood determined using the Ultra-Flo 100 Platelet Counter. Thromb Haemost (1982) 1.25
Pilot studies on recombinant cold-adapted live type A and B influenza virus vaccines. J Infect Dis (1977) 1.25
Effects of N-acetylcysteine on acetaminophen covalent binding and hepatic necrosis in mice. J Pharmacol Exp Ther (1985) 1.24
Hepatic glutathione homeostasis in the rat: efflux accounts for glutathione turnover. Hepatology (1984) 1.23
Developments in understanding the basis of cooked-rice texture. Crit Rev Food Sci Nutr (2000) 1.23
Effect of oral contraceptive agents on platelets and plasma-phospholipids. Lancet (1968) 1.23
Oestrogen treatment for menopausal flushing. Br Med J (1977) 1.21
The clinical response to minocycline in multiple sclerosis is accompanied by beneficial immune changes: a pilot study. Mult Scler (2007) 1.18
Impact of particle size distribution on rheological and textural properties of chocolate models with reduced fat content. J Food Sci (2007) 1.18
Biliary excretion of glutathione and glutathione disulfide in the rat. Regulation and response to oxidative stress. J Clin Invest (1984) 1.18
Molecular basis for several drug-induced nephropathies. Am J Med (1977) 1.18
Acute pulmonary injury in rats by nitrofurantoin and modification by vitamin E, dietary fat, and oxygen. Am Rev Respir Dis (1979) 1.18