Alteration of the quality of milk by expression of sheep beta-lactoglobulin in transgenic mice.

PubWeight™: 1.66‹?› | Rank: Top 3%

🔗 View Article (PMID 3614356)

Published in Nature on September 08, 1987

Authors

J P Simons, M McClenaghan, A J Clark

Articles citing this

Two alleles of a neural protein gene linked to scrapie in sheep. Proc Natl Acad Sci U S A (1990) 1.84

A milk protein gene promoter directs the expression of human tissue plasminogen activator cDNA to the mammary gland in transgenic mice. Proc Natl Acad Sci U S A (1988) 1.49

Variegated transgene expression in mouse mammary gland is determined by the transgene integration locus. Proc Natl Acad Sci U S A (1996) 1.40

High-level expression of biologically active human alpha 1-antitrypsin in the milk of transgenic mice. Proc Natl Acad Sci U S A (1990) 1.32

Position-independent expression of the ovine beta-lactoglobulin gene in transgenic mice. Biochem J (1992) 1.24

Tissue-specific expression of the rat beta-casein gene in transgenic mice. Nucleic Acids Res (1988) 1.16

Interaction of DNA-binding proteins with a milk protein gene promoter in vitro: identification of a mammary gland-specific factor. Nucleic Acids Res (1991) 1.11

Genomic analysis of the major bovine milk protein genes. Nucleic Acids Res (1990) 1.07

Differential regulation of rat beta-casein-chloramphenicol acetyltransferase fusion gene expression in transgenic mice. Mol Cell Biol (1989) 1.06

Tissue-specific, high level expression of the rat whey acidic protein gene in transgenic mice. Nucleic Acids Res (1990) 1.04

Milk composition and lactation of beta-casein-deficient mice. Proc Natl Acad Sci U S A (1994) 1.03

High-level synthesis of a heterologous milk protein in the mammary glands of transgenic swine. Proc Natl Acad Sci U S A (1991) 1.02

A novel cell culture model for studying differentiation and apoptosis in the mouse mammary gland. Breast Cancer Res (2000) 1.01

Complete nucleotide sequence of the genomic ovine beta-lactoglobulin gene. Nucleic Acids Res (1988) 0.97

Mammalian cDNA and prokaryotic reporter sequences silence adjacent transgenes in transgenic mice. Nucleic Acids Res (1997) 0.97

Use of transgenic animals in biotechnology: prospects and problems. Acta Naturae (2013) 0.96

High-level expression of the rat whey acidic protein gene is mediated by elements in the promoter and 3' untranslated region. Mol Cell Biol (1992) 0.96

Transgenic mice secreting coronavirus neutralizing antibodies into the milk. J Virol (1998) 0.93

Tissue-specific expression in the salivary glands of transgenic mice. Nucleic Acids Res (1992) 0.91

Genomic organization of the bovine alpha-S1 casein gene. Nucleic Acids Res (1991) 0.90

Multiple effects of genetic background on variegated transgene expression in mice. Genetics (2002) 0.88

Genome editing revolutionize the creation of genetically modified pigs for modeling human diseases. Hum Genet (2016) 0.88

Secretory proteins compete for production in the mammary gland of transgenic mice. Biochem J (1995) 0.86

Conserved region of the rat alpha-lactalbumin promoter is a target site for protein binding in vitro. Biochem J (1988) 0.85

A quick and efficient system for antibiotic-free expression of heterologous genes in tobacco roots. Plant Cell Rep (2004) 0.83

Fixing human factor IX (fIX): correction of a cryptic RNA splice enables the production of biologically active fIX in the mammary gland of transgenic mice. Proc Natl Acad Sci U S A (1995) 0.81

Mammary development and milk secretion in transgenic mice expressing the sheep beta-lactoglobulin gene. Biochem J (1992) 0.81

Elements within the beta-lactoglobulin gene inhibit expression of human serum albumin cDNA and minigenes in transfected cells but rescue their expression in the mammary gland of transgenic mice. Nucleic Acids Res (1996) 0.78

Could protein tertiary structure influence mammary transgene expression more than tissue specific codon usage? Transgenic Res (2010) 0.78

Comparative proteomics of milk fat globule membrane proteins from transgenic cloned cattle. PLoS One (2014) 0.77

Transgenic mice carrying the guinea-pig alpha-lactalbumin gene transcribe milk protein genes in their sebaceous glands during lactation. Biochem J (1991) 0.75

Transgenic bovine as bioreactors: Challenges and perspectives. Bioengineered (2016) 0.75

Articles by these authors

A proposal for a uniform nomenclature in bacterial genetics. Genetics (1966) 31.92

The Influence of Ions upon the Action of Digitalis. Proc R Soc Med (1912) 24.21

Genetic location of certain mutations conferring recombination deficiency in Escherichia coli. J Bacteriol (1969) 11.34

The reaction between acetyl choline and muscle cells. J Physiol (1926) 9.75

Recombination deficient mutants of E. coli and other bacteria. Annu Rev Genet (1973) 9.55

Beginning a genetic analysis of conjugational transfer determined by the F factor in Escherichia coli by isolation and characterization of transfer-deficient mutants. J Bacteriol (1971) 8.45

Abnormal metabolic response to ultraviolet light of a recombination deficient mutant of Escherichia coli K12. J Mol Biol (1966) 8.39

Genetic analysis of the recF pathway to genetic recombination in Escherichia coli K12: isolation and characterization of mutants. J Mol Biol (1973) 7.34

The beginning of a genetic analysis of recombination proficiency. J Cell Physiol (1967) 7.09

Characteristics of some multiply recombination-deficient strains of Escherichia coli. J Bacteriol (1969) 7.04

The antagonism of acetyl choline by atropine. J Physiol (1926) 6.99

Genetic recombination in Escherichia coli: the role of exonuclease I. Proc Natl Acad Sci U S A (1971) 6.74

Biochemical and genetic studies of recombination proficiency in Escherichia coli. I. Enzymatic activity associated with recB+ and recC+ genes. Proc Natl Acad Sci U S A (1970) 6.42

Behavior of lambda bacteriophage in a recombination deficienct strain of Escherichia coli. J Virol (1967) 6.38

Biochemical and genetic studies of recombination proficiency in Escherichia coli. II. Rec+ revertants caused by indirect suppression of rec- mutations. Proc Natl Acad Sci U S A (1970) 6.19

The action of ions upon the frog's heart. J Physiol (1921) 5.54

The metabolism of the isolated heart of the frog. J Physiol (1931) 5.18

Deletions generated by the transposon Tn10 in the srl recA region of the Escherichia coli K-12 chromosome. Genetics (1979) 4.75

Construction of an Hfr strain useful for transferring recA mutations between Escherichia coli strains. J Bacteriol (1980) 4.61

Linkage of adult alpha- and beta-globin genes in X. laevis and gene duplication by tetraploidization. Cell (1980) 4.09

The anaerobic activity of the isolated frog's heart. J Physiol (1932) 4.00

Detection and characterization of plasmids in Pseudomonas aeruginosa strain PAO. J Bacteriol (1973) 4.00

Genetic analysis of the RecE pathway of genetic recombination in Escherichia coli K-12. J Bacteriol (1981) 3.99

Comparison of Chlamydia psittaci isolates by DNA restriction endonuclease analysis. Infect Immun (1984) 3.78

The action of ions and lipoids upon the frog's heart. J Physiol (1913) 3.78

Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I gene. N Engl J Med (1996) 3.73

The oxygen consumption of the frog's heart: I. J Physiol (1928) 3.63

Conjugal transmission of plasmids. Annu Rev Genet (1979) 3.34

Conjugational complementation analysis of transfer-deficient mutants of Flac in Escherichia coli. J Bacteriol (1972) 3.28

Amplification and enhanced expression of the epidermal growth factor receptor gene in A431 human carcinoma cells. Science (1984) 3.06

Indirect suppression of recB and recC mutations by exonuclease I deficiency. Proc Natl Acad Sci U S A (1972) 3.03

The carbohydrate metabolism of the isolated heart of the frog. J Physiol (1932) 2.92

Genetic analysis of the recJ gene of Escherichia coli K-12. J Bacteriol (1984) 2.90

The reaction between acetyl choline and muscle cells: Part II. J Physiol (1927) 2.89

Plasmid and bacteriophage vectors for excision of intact inserts. Gene (1987) 2.81

Molecular cloning of DNA from F sex factor of Escherichia coli K-12. Proc Natl Acad Sci U S A (1976) 2.81

Linkage of the angiotensinogen gene to essential hypertension. N Engl J Med (1994) 2.80

Characterization of REP- mutants and their interaction with P2 phage. Virology (1970) 2.77

Synthesis of linear plasmid multimers in Escherichia coli K-12. J Bacteriol (1986) 2.65

Interaction of the recombination pathways of bacteriophage lambda and its host Escherichia coli K12: effects on exonuclease V activity. J Mol Biol (1972) 2.64

Toward a metabolic interpretation of genetic recombination of E. coli and its phages. Annu Rev Microbiol (1971) 2.61

Isolation of exonuclease VIII: the enzyme associated with sbcA indirect suppressor. Proc Natl Acad Sci U S A (1974) 2.60

Pharmacological management of chronic neuropathic pain - consensus statement and guidelines from the Canadian Pain Society. Pain Res Manag (2007) 2.59

A survey of prelicensure pain curricula in health science faculties in Canadian universities. Pain Res Manag (2009) 2.49

Phosphagen in the perfused heart of the frog. J Physiol (1932) 2.39

Human epidermal growth factor receptor cDNA is homologous to a variety of RNAs overproduced in A431 carcinoma cells. Nature (1984) 2.36

Assignment of tra cistrons to EcoRI fragments of F sex factor DNA. J Bacteriol (1978) 2.32

Genetic analysis of mutations indirectly suppressing recB and recC mutations. Genetics (1972) 2.26

The influence of oxygen supply on the response of the isolated intestine to drugs. J Physiol (1923) 2.17

Molecular analysis of the recF gene of Escherichia coli. Proc Natl Acad Sci U S A (1984) 2.09

Structure and localization of genes encoding aberrant and normal epidermal growth factor receptor RNAs from A431 human carcinoma cells. Mol Cell Biol (1985) 2.02

Differential suppression of priA2::kan phenotypes in Escherichia coli K-12 by mutations in priA, lexA, and dnaC. Genetics (1996) 2.01

Progress toward a metabolic interpretation of genetic recombination of Escherichia coli and bacteriophage lambda. Genetics (1974) 2.00

The dependence of postreplication repair on uvrB in a recF mutant of Escherichia coli K-12. Mol Gen Genet (1977) 1.93

Deletion of the alpha(1,3)galactosyl transferase (GGTA1) gene and the prion protein (PrP) gene in sheep. Nat Biotechnol (2001) 1.90

Physical mapping of the srl recA region of Escherichia coli: analysis of Tn10 generated insertions and deletions. Mol Gen Genet (1981) 1.88

Triple A syndrome is caused by mutations in AAAS, a new WD-repeat protein gene. Hum Mol Genet (2001) 1.83

RadA protein is an archaeal RecA protein homolog that catalyzes DNA strand exchange. Genes Dev (1998) 1.80

recA-like genes from three archaean species with putative protein products similar to Rad51 and Dmc1 proteins of the yeast Saccharomyces cerevisiae. Nucleic Acids Res (1996) 1.76

Genetic analysis of regulation of the RecF pathway of recombination in Escherichia coli K-12. J Bacteriol (1983) 1.75

Analysis of the role of recombination and repair in mutagenesis of Escherichia coli by UV irradiation. Genetics (1977) 1.74

Overproduction of the Escherichia coli recA protein without stimulation of its proteolytic activity. J Bacteriol (1981) 1.68

Evolutionary comparisons of RecA-like proteins across all major kingdoms of living organisms. J Mol Evol (1997) 1.67

Defective excision and postreplication repair of UV-damaged DNA in a recL mutant strain of E. coli K-12. Mol Gen Genet (1977) 1.67

A DNA variant at the angiotensin-converting enzyme gene locus associates with coronary artery disease in the Caerphilly Heart Study. Circulation (1995) 1.66

Isolation and characterization of an Escherichia coli strain harboring three sex factors. Genetics (1968) 1.64

The influence of oxygen pressure on the metabolism of the isolated cold-blooded heart. J Physiol (1933) 1.64

Biosynthetic human insulin in the treatment of diabetes. A double-blind crossover trial in established diabetic patients. Lancet (1982) 1.64

Genes of the RecE and RecF pathways of conjugational recombination in Escherichia coli. Cold Spring Harb Symp Quant Biol (1984) 1.64

Two main groups of mouse major urinary protein genes, both largely located on chromosome 4. EMBO J (1982) 1.63

Production of a merodiploid strain from a double male strain of E. coli K12. Mol Gen Genet (1969) 1.62

Linkage of the gene for the triple A syndrome to chromosome 12q13 near the type II keratin gene cluster. Hum Mol Genet (1996) 1.59

Genetic and physical mapping of recF in Escherichia coli K-12. Mol Gen Genet (1980) 1.55

Assessment of painful late effects of lumbar spinal fusion with SPECT. J Nucl Med (1994) 1.54

Diabetic impotence: studies of nocturnal erection during REM sleep. Br Med J (1979) 1.50

Evidence that rnmB is the operator of the Escherichia coli recA gene. Proc Natl Acad Sci U S A (1981) 1.50

cis-Dominant, transfer-deficient mutants of the Escherichia coli K-12 F sex factor. J Bacteriol (1976) 1.50

A homozygous splice site mutation affecting the intracellular domain of the growth hormone (GH) receptor resulting in Laron syndrome with elevated GH-binding protein. J Clin Endocrinol Metab (1996) 1.49

Cloning and expression of a novel angiotensin II receptor subtype. J Biol Chem (1992) 1.47

DNA methylation and silencing of gene expression. Trends Endocrinol Metab (2001) 1.46

Properties of a mutant recA-encoded protein reveal a possible role for Escherichia coli recF-encoded protein in genetic recombination. Proc Natl Acad Sci U S A (1988) 1.46

Sequence-specific recombination of plasmid ColE1. Proc Natl Acad Sci U S A (1980) 1.46

Prophage F116: evidence for extrachromosomal location in Pseudomonas aeruginosa strain PAO. J Virol (1977) 1.41

Structure of mouse major urinary protein genes: different splicing configurations in the 3'-non-coding region. EMBO J (1984) 1.41

Epidermal growth factor regulates the expression of its own receptor. Proc Natl Acad Sci U S A (1985) 1.41

Laparoscopic resection of advanced colorectal cancer. Br J Surg (2010) 1.41

Interaction of the recombination pathways of bacteriophage lambda and host Escherichia coli: effects on lambda recombination. J Mol Biol (1972) 1.40

Variegated transgene expression in mouse mammary gland is determined by the transgene integration locus. Proc Natl Acad Sci U S A (1996) 1.40

The ideal ileal-pouch design: a long-term randomized control trial of J- vs W-pouch construction. Dis Colon Rectum (2012) 1.39

Back pain without apparent cause. CMAJ (1996) 1.39

Suppressibility of recA, recB, and recC mutations by nonsense suppressors. J Bacteriol (1978) 1.38

Anthropometric measurements of white and black southern adolescent girls. J Am Diet Assoc (1990) 1.38

Transposon-mediated conjugational transmission of nonconjugative plasmids. J Bacteriol (1980) 1.37

Characterization of the gene encoding ovine beta-lactoglobulin. Similarity to the genes for retinol binding protein and other secretory proteins. J Mol Biol (1988) 1.32

High-level expression of biologically active human alpha 1-antitrypsin in the milk of transgenic mice. Proc Natl Acad Sci U S A (1990) 1.32

Elevated epidermal growth factor receptor gene copy number and expression in a squamous carcinoma cell line. J Clin Invest (1985) 1.32

Pharmacological management of chronic neuropathic pain: revised consensus statement from the Canadian Pain Society. Pain Res Manag (2014) 1.31