Published in Br J Clin Pharmacol on July 01, 1987
Evidence and consensus-based German guidelines for the management of analgesia, sedation and delirium in intensive care--short version. Ger Med Sci (2010) 1.30
Paracetamol poisoning in children and hepatotoxicity. Br J Clin Pharmacol (1991) 1.25
Evidence and consensus based guideline for the management of delirium, analgesia, and sedation in intensive care medicine. Revision 2015 (DAS-Guideline 2015) - short version. Ger Med Sci (2015) 0.94
Clinical pharmacology of the perinatal period and early infancy. Clin Pharmacokinet (1989) 0.93
Pharmacokinetics and metabolism of rectally administered paracetamol in preterm neonates. Arch Dis Child Fetal Neonatal Ed (1999) 0.91
Paracetamol: a focus for the general pediatrician. Eur J Pediatr (2013) 0.87
Breastfeeding and migraine drugs. Eur J Clin Pharmacol (2014) 0.78
Perinatal paracetamol exposure in mice does not affect the development of allergic airways disease in early life. Thorax (2015) 0.75
Development of an in vitro cell culture model to study milk to plasma ratios of therapeutic drugs. Indian J Pharmacol (2013) 0.75
Exposure to mercury and aluminum in early life: developmental vulnerability as a modifying factor in neurologic and immunologic effects. Int J Environ Res Public Health (2015) 0.75
Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism. J Pharmacol Exp Ther (1973) 4.40
Acetaminophen-induced hepatic injury: protective role of glutathione in man and rationale for therapy. Clin Pharmacol Ther (1974) 2.62
Acetaminophen elimination kinetics in neonates, children, and adults. Clin Pharmacol Ther (1976) 2.24
Paracetamol metabolism following overdosage: application of high performance liquid chromatography. J Pharm Pharmacol (1977) 2.01
Kinetics and metabolism of paracetamol and phenacetin. Br J Clin Pharmacol (1980) 1.87
High performance liquid chromatographic estimation of paracetamol metabolites in plasma. Br J Clin Pharmacol (1978) 1.78
Pharmacokinetics of acetaminophen in the human neonate: formation of acetaminophen glucuronide and sulfate in relation to plasma bilirubin concentration and D-glucaric acid excretion. Pediatrics (1975) 1.52
Paracetamol overdose in man: relationship between pattern of urinary metabolites and severity of liver damage. Q J Med (1976) 1.03
Acetaminophen kinetics in acutely poisoned patients. Clin Pharmacol Ther (1979) 1.03
Drugs taken by mothers in the puerperium: inpatient survey in Northern Ireland. Br Med J (Clin Res Ed) (1984) 1.00
Analgesic drugs in breast milk and plasma. Clin Pharmacol Ther (1981) 0.98
Excretion of paracetamol in human breast milk. Eur J Clin Pharmacol (1981) 0.90
Disposition of acetaminophen in milk, saliva, and plasma of lactating women. Pediatr Pharmacol (New York) (1980) 0.89
Drugs taken by mothers in the puerperium. Br Med J (Clin Res Ed) (1985) 0.87
False positives and negatives in routine testing for drugs of abuse. Lancet (1995) 2.02
Differential induction of antipyrine metabolism by rifampicin. Eur J Clin Pharmacol (1981) 1.81
Comparison of the new miniature Wright peak flow meter with the standard Wright peak flow meter. Thorax (1979) 1.38
Effects of dextran infusion on the adhesiveness of human blood-platelets. Lancet (1966) 1.19
Effect of rifampicin on metoprolol and antipyrine kinetics. Br J Clin Pharmacol (1982) 1.15
Myopericarditis complicating ulcerative colitis. Br Heart J (1974) 1.10
Single-dose pharmacokinetic and pharmacodynamic comparison of polymer-matrix (Slow Trasicor) and Oros dosage forms of oxprenolol in healthy volunteers. Br J Clin Pharmacol (1985) 1.05
Lead poisoning: case studies. Br J Clin Pharmacol (2002) 1.04
Kinetics of paraquat elimination in the dog. Toxicol Appl Pharmacol (1981) 1.00
Sperm chromatin damage associated with male smoking. Mutat Res (1999) 0.99
Postoperative changes in platelet adhesiveness. J Clin Pathol (1967) 0.97
Seminal plasma reduces exogenous oxidative damage to human sperm, determined by the measurement of DNA strand breaks and lipid peroxidation. Mutat Res (2000) 0.96
Potential drug interactions with misoprostol: effects on the pharmacokinetics of antipyrine and propranolol. Postgrad Med J (1988) 0.95
Competition for sulphate during detoxification in the gut wall. Nature (1975) 0.94
Role of erythrocytes in the acute platelet response to operation. J Clin Pathol (1968) 0.93
Method for the determination of acemetacin, a non-steroidal anti-inflammatory drug, in plasma by high-performance liquid chromatography. J Chromatogr (1987) 0.92
Effect of oestriol on platelet adhesiveness and fibrinolysis in men. Lancet (1966) 0.91
Maternal and neonatal disposition of pethidine in childbirth--a study using quantitative gas chromatography-mass spectrometry. Life Sci (1978) 0.89
Caffeine phenotyping of cytochrome P4501A2, N-acetyltransferase, and xanthine oxidase in patients with familial adenomatous polyposis. Gut (1995) 0.89
In vivo absorption studies with paraquat and diquat in the dog [proceedings]. Br J Pharmacol (1976) 0.87
Rapid method for the routine determination of caffeine and its metabolites by high-performance liquid chromatography. J Chromatogr (1994) 0.86
Antioxidant capacity of the epididymis. Hum Reprod (1999) 0.85
Metabolism of aspirin after therapeutic and toxic doses. Hum Exp Toxicol (1990) 0.85
The effect of cimetidine and ranitidine on paracetamol glucuronidation and sulphation in cultured rat hepatocytes. Biochem Pharmacol (1985) 0.84
Pharmacokinetics of lidocaine and its deethylated metabolite: dose and time dependency studies in man. J Pharmacokinet Biopharm (1982) 0.83
Influence of route of hepatic administration on drug availability. J Pharmacol Exp Ther (1984) 0.82
Caffeine as a metabolic probe: a comparison of the metabolic ratios used to assess CYP1A2 activity. Br J Clin Pharmacol (1995) 0.82
Observations on the measurement of platelet adhesiveness with the glassbead column technique. Scand J Haematol (1968) 0.81
Comparative metabolism of high doses of aspirin in man and rat. Xenobiotica (1990) 0.81
The comparative pharmacokinetics of acemetacin in young subjects and elderly patients. Br J Clin Pharmacol (1991) 0.80
Effect of glucose on platelet adhesiveness. J Atheroscler Res (1967) 0.80
Effects of carbenoxolone sodium and of aspirin on gastric mucosal potential difference in normal subjects. Scand J Gastroenterol (1975) 0.79
A double blind trial of carbenoxolone and geranyl farnesyl acetate in gastric ulcer. Scand J Gastroenterol (1975) 0.79
Stereoselective microsomal N-oxidation of N-ethyl-N-methylaniline. Biochem Pharmacol (1993) 0.78
Metabolic profiling of body fluids by proton NMR: self-poisoning episodes with paracetamol (acetaminophen). Magn Reson Med (1988) 0.78
Effect of diazepam on unstimulated and on stimulated gastric secretion. Scand J Gastroenterol (1975) 0.78
An in vitro technique for the rapid determination of drug entry into breast milk. Br J Clin Pharmacol (1995) 0.78
Effect of physical exercise on platelet adhesiveness. Scand J Haematol (1972) 0.77
Identification of a melanocortin receptor expressed by murine brain microvascular endothelial cells in culture. Microvasc Res (1995) 0.77
Caffeine as a metabolic probe: NAT2 phenotyping. Br J Clin Pharmacol (1996) 0.77
Non-human primate species as metabolic models for the human situation: comparative studies on meperidine metabolism. Toxicol Appl Pharmacol (1979) 0.77
Some observations on the pharmacology of 'deep-heat', a topical rubifacient. Ann Rheum Dis (1984) 0.76
Routine determination of organochlorine pesticides and polychlorinated biphenyls in human milk using capillary gas chromatography-mass spectrometry. Analyst (1987) 0.76
Diazepam metabolism in cultured hepatocytes from rat, rabbit, dog, guinea pig, and man. Drug Metab Dispos (1987) 0.76
Depletion of plasma glycine and effect of glycine by mouth on salicylate metabolism during aspirin overdose. Hum Exp Toxicol (1990) 0.76
Free thiomalate levels in rheumatoid arthritis. Ann Rheum Dis (1985) 0.75
Asymmetric metabolic N-oxidation of N-ethyl-N-methylaniline by purified flavin-containing monooxygenase. Chirality (1994) 0.75
Models of hepatic drug clearance: discrimination between the 'well stirred' and 'parallel-tube' models. J Pharm Pharmacol (1983) 0.75
Pethidine pharmacokinetics in dog" dose and time studies [proceedings]. Br J Pharmacol (1976) 0.75
Misoprostol does not alter the pharmacokinetics of propranolol. Postgrad Med J (1991) 0.75
Clinical trials. Br J Clin Pharmacol (1975) 0.75
European Ethical Review Committee: the experience of an international ethics committee reviewing protocols for drug trials. Br Med J (Clin Res Ed) (1984) 0.75
Species variability in the stereoselective N-oxidation of pargyline. Chirality (1994) 0.75
Disposition of pethidine in childbirth. Br J Anaesth (1978) 0.75
Interaction of cimetidine and ranitidine with the FAD monooxygenase in pig liver microsomes. Biochem Pharmacol (1985) 0.75
Digoxin and cimetidine: investigation of the potential for a drug interaction. Hum Toxicol (1985) 0.75
Antipyrine metabolism in cultured rat hepatocytes. Biochem Pharmacol (1987) 0.75
Species differences in the stereoselectivity of N-oxygenation of N-ethyl-N-methylaniline in vitro. Chirality (1996) 0.75
Effect of dextran 70 infusion on platelet adhesiveness after operation. Br J Surg (1968) 0.75
Epoxides from paracetamol - a possible explanation for paracetamol toxicity. Adv Exp Med Biol (1981) 0.75
The interaction of temelastine with cytochrome P450 mixed-function oxidase enzymes in vivo and in vitro. Biochem Pharmacol (1989) 0.75
An unusual helical micro-organism found in the gut lumen of human subjects. J Med Microbiol (1999) 0.75
Spirochaetes in small bowel. Lancet (1995) 0.75
Lignocaine kinetics in the rat. J Pharm Pharmacol (1984) 0.75
Clinical pharmacology in the Health Service: a progress report. Health Trends (1982) 0.75
Large-scale separation of lipids from organochlorine pesticides and polychlorinated biphenyls using a polymeric high-performance liquid chromatographic column. Analyst (1986) 0.75
The acute action of fenbufen and piroxicam on the gastric mucosa as measured by gastric microbleeding. J Int Med Res (1984) 0.75
The antipyrine breath test in the rat: a pharmacokinetic model. Eur J Drug Metab Pharmacokinet (1989) 0.75
Placental transfer of pethidine and bupivacaine. Neuropharmacology (1981) 0.75
Acute gastric microbleeding after aspirin ingestion, compared with a similar dose of fenbufen by measurement of haemoglobin in gastric aspirates. J Pharm Pharmacol (1983) 0.75
Gastric mucosal damage by anti-inflammatory drugs. Rheumatol Phys Med (1972) 0.75
Limitations in the use of nickel boride dechlorination for the analysis of polychlorinated biphenyls. Bull Environ Contam Toxicol (1986) 0.75
A competitive single-step reverse transcriptase-polymerase chain reaction assay for quantification of heme oxygenase 1. Anal Biochem (1996) 0.75
Evaluation of nitrogen balance of young women fed amino acids proportioned as in the FAO provisional pattern and as in egg, oats, milk and peanuts. Am J Clin Nutr (1965) 0.75
Primary cultures of adult rat hepatocytes--a model for the toxicity of histamine H2-receptor antagonists. Toxicology (1985) 0.75
Characteristics of ulcers of the small bowel induced by non-steroidal anti-inflammatory drugs in the rat: implications for clinical practice. Br J Rheumatol (1995) 0.75
Melanocortin probes for the melanoma MC1 receptor: synthesis, receptor binding and biological activity. Melanoma Res (1996) 0.75
Pharmacokinetics of a single dose of ofloxacin in healthy elderly subjects using noncompartmental and compartmental models. Pharm Weekbl Sci (1989) 0.75
The interaction of omeprazole with rat liver cytochrome P450-mediated monooxygenase reactions in vitro and in vivo. Biochem Pharmacol (1988) 0.75
The metabolism of bupivacaine in the rat [proceedings]. Br J Pharmacol (1977) 0.75
Effect of dextran on platelet behaviour after abdominal operations. Acta Chir Scand Suppl (1968) 0.75
Extra-epididymal spermatozoa express nuclear abnormalities. Int J Androl (1999) 0.75
Clean-up and separation of chlorobiphenyl isomers after synthesis by Cadogan coupling using preparative high-performance liquid chromatography. J Chromatogr (1986) 0.75
Clinical pharmacology in the NHS. J R Soc Med (1979) 0.75
Rapid and simple chromatographic method for the determination of diazepam and its major metabolites in human plasma and urine. J Chromatogr B Biomed Sci Appl (1998) 0.75
Barium X-ray study of the small bowel in patients with rheumatoid arthritis taking non-steroidal anti-inflammatory drugs did not disclose ulceration. Br J Rheumatol (1994) 0.75
Evidence for the internalization of [125I-Tyr2, Nle4, D-Phe7] alpha-MSH following binding to the MSH receptor of B16 murine melanoma cells. Ann N Y Acad Sci (1993) 0.75
A cleavable biotinylated photoactivable derivative of alpha-MSH. Its application to the characterization and isolation of the alpha-MSH receptor. Ann N Y Acad Sci (1993) 0.75
Pre-medication for endoscopy. A trial of atropine, pentazocine or pethidine as a supplement to diazepam. Scand J Gastroenterol (1978) 0.75