The role of glutathione in determining the response of normal and tumor cells to anticancer drugs.

PubWeight™: 0.92‹?›

🔗 View Article (PMID 3678588)

Published in Biochem Soc Trans on August 01, 1987

Authors

C R Wolf1, A D Lewis, J Carmichael, D J Adams, S G Allan, D J Ansell

Author Affiliations

1: Imperial Cancer Research Fund, University Department of Biochemistry, Edinburgh, U.K.

Articles by these authors

Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial. Lancet (2000) 12.56

Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing. Cancer Res (1987) 10.80

The permeability of the endplate channel to organic cations in frog muscle. J Gen Physiol (1980) 5.00

The permeability of endplate channels to monovalent and divalent metal cations. J Gen Physiol (1980) 4.72

Topotecan versus paclitaxel for the treatment of recurrent epithelial ovarian cancer. J Clin Oncol (1997) 3.61

Topotecan versus cyclophosphamide, doxorubicin, and vincristine for the treatment of recurrent small-cell lung cancer. J Clin Oncol (1999) 3.48

Tensile properties of the human femur-anterior cruciate ligament-tibia complex. The effects of specimen age and orientation. Am J Sports Med (1991) 2.64

Origins of skeletal pain: sensory and sympathetic innervation of the mouse femur. Neuroscience (2002) 2.57

Ionic currents in molluscan soma. Annu Rev Neurosci (1980) 2.57

Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of radiosensitivity. Cancer Res (1987) 2.56

Treatment of advanced breast cancer with sterically stabilized liposomal doxorubicin: results of a multicenter phase II trial. J Clin Oncol (1997) 2.39

Gemcitabine plus best supportive care (BSC) vs BSC in inoperable non-small cell lung cancer--a randomized trial with quality of life as the primary outcome. UK NSCLC Gemcitabine Group. Non-Small Cell Lung Cancer. Br J Cancer (2000) 2.30

Comparison of short-term and continuous chemotherapy (mitozantrone) for advanced breast cancer. Lancet (1990) 2.25

Phase I study of bryostatin 1: assessment of interleukin 6 and tumor necrosis factor alpha induction in vivo. The Cancer Research Campaign Phase I Committee. J Natl Cancer Inst (1993) 2.22

Reductase enzyme expression across the National Cancer Institute Tumor cell line panel: correlation with sensitivity to mitomycin C and EO9. J Natl Cancer Inst (1996) 2.20

Characteristics of sodium and calcium conductance changes produced by membrane depolarization in an Aplysia neurone. J Physiol (1979) 2.06

Block of endplate channels by permeant cations in frog skeletal muscle. J Gen Physiol (1981) 2.00

Effects of heat shock, heat shock protein 40 (HDJ-2), and proteasome inhibition on protein aggregation in cellular models of Huntington's disease. Proc Natl Acad Sci U S A (2000) 1.88

Direct measurement of pO2 distribution and bioreductive enzymes in human malignant brain tumors. Int J Radiat Oncol Biol Phys (1994) 1.84

Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease. Hum Mol Genet (2001) 1.81

Corticosteroid resistance in chronic asthma. Br Med J (Clin Res Ed) (1981) 1.75

Calcium entry through receptor-operated channels in bovine pulmonary artery endothelial cells. Tissue Cell (1987) 1.74

A novel mechanism of inhibition of high-voltage activated calcium channels by α-conotoxins contributes to relief of nerve injury-induced neuropathic pain. Pain (2011) 1.65

Brevetoxin-3 (PbTx-3) and its derivatives modulate single tetrodotoxin-sensitive sodium channels in rat sensory neurons. J Pharmacol Exp Ther (1998) 1.63

A randomised trial of oral versus intravenous topotecan in patients with relapsed epithelial ovarian cancer. Eur J Cancer (2002) 1.62

Can clinical pharmacists affect SF-36 scores in veterans at high risk for medication-related problems? Med Care (2001) 1.61

Randomized double-blind phase II survival study comparing immunization with the anti-idiotypic monoclonal antibody 105AD7 against placebo in advanced colorectal cancer. Br J Cancer (2001) 1.56

Comparison of twice daily administration of a new corticosteroid budesonide with beclomethasone dipropionate four times daily in the treatment of chronic asthma. Br J Dis Chest (1982) 1.55

Strains of Mycobacterium tuberculosis differ in susceptibility to reactive nitrogen intermediates in vitro. Infect Immun (1994) 1.51

Association between expression of activated 72-kilodalton gelatinase and tumor spread in non-small-cell lung carcinoma. J Natl Cancer Inst (1993) 1.49

Calcium-activated potassium channels in native endothelial cells from rabbit aorta: conductance, Ca2+ sensitivity and block. J Physiol (1992) 1.49

Cellular heterogeneity and drug resistance in two ovarian adenocarcinoma cell lines derived from a single patient. Int J Cancer (1987) 1.47

The activating mutation R201C in GNAS promotes intestinal tumourigenesis in Apc(Min/+) mice through activation of Wnt and ERK1/2 MAPK pathways. Oncogene (2010) 1.45

Comparison of salbutamol given intravenously and by intermittent positive-pressure breathing in life-threatening asthma. Br Med J (1979) 1.41

Adenosine triphosphate-evoked currents in cultured neurones dissociated from rat parasympathetic cardiac ganglia. J Physiol (1991) 1.41

The RASSF1A isoform of RASSF1 promotes microtubule stability and suppresses tumorigenesis. Mol Cell Biol (2005) 1.40

Effects of nonsteroidal anti-inflammatory drugs on prostaglandins and renal function. Am J Med (1985) 1.39

Multifactorial mechanisms associated with broad cross-resistance of ovarian carcinoma cells selected by cyanomorpholino doxorubicin. Cancer Res (1991) 1.39

Adjuvant chemotherapy for non-metastatic osteosarcoma of the extremities in two New Zealand cancer centres. Aust N Z J Med (1995) 1.38

Micro-CT enables microlocalisation and quantification of Her2-targeted gold nanoparticles within tumour regions. Br J Radiol (2010) 1.36

Acetylcholine-evoked currents in cultured neurones dissociated from rat parasympathetic cardiac ganglia. J Physiol (1991) 1.35

Gating currents associated with sodium and calcium currents in an Aplysia neuron. Science (1976) 1.35

Ionic currents in response to membrane depolarization in an Aplysia neurone. J Physiol (1979) 1.34

Chemosensitivity testing of human colorectal carcinoma cell lines using a tetrazolium-based colorimetric assay. Cancer Res (1987) 1.34

Randomized trial of paclitaxel plus supportive care versus supportive care for patients with advanced non-small-cell lung cancer. J Natl Cancer Inst (2000) 1.33

A phase I study of the safety and tolerability of olaparib (AZD2281, KU0059436) and dacarbazine in patients with advanced solid tumours. Br J Cancer (2011) 1.31

Topoisomerase II alpha co-amplification with erbB2 in human primary breast cancer and breast cancer cell lines: relationship to m-AMSA and mitoxantrone sensitivity. Oncogene (1993) 1.30

Tamoxifen as primary treatment of breast cancer in elderly or frail patients: a practical management. Br Med J (Clin Res Ed) (1985) 1.29

The relationship of brevetoxin 'length' and A-ring functionality to binding and activity in neuronal sodium channels. Chem Biol (1995) 1.28

Interaction of azole antifungal antibiotics with cytochrome P-450-dependent 14 alpha-sterol demethylase purified from Candida albicans. Biochem J (1990) 1.27

muO-conotoxin MrVIB selectively blocks Nav1.8 sensory neuron specific sodium channels and chronic pain behavior without motor deficits. Proc Natl Acad Sci U S A (2006) 1.26

Synchronized oscillations in cytoplasmic free calcium concentration in confluent bradykinin-stimulated bovine pulmonary artery endothelial cell monolayers. J Biol Chem (1989) 1.23

Novel omega-conotoxins from Conus catus discriminate among neuronal calcium channel subtypes. J Biol Chem (2000) 1.23

Membrane potential and Na(+)-K+ pump activity modulate resting and bradykinin-stimulated changes in cytosolic free calcium in cultured endothelial cells from bovine atria. J Biol Chem (1990) 1.23

Sodium and calcium gating currents in an Aplysia neurone. J Physiol (1979) 1.22

Interaction of internal anions with potassium channels of the squid giant axon. J Gen Physiol (1983) 1.22

Estrogen induced synthesis of specific proteins in human breast cancer cells. Biochem Biophys Res Commun (1980) 1.22

Clinical and economic impact of ambulatory care clinical pharmacists in management of dyslipidemia in older adults: the IMPROVE study. Impact of Managed Pharmaceutical Care on Resource Utilization and Outcomes in Veterans Affairs Medical Centers. Pharmacotherapy (2000) 1.22

An economic analysis of a randomized, controlled, multicenter study of clinical pharmacist interventions for high-risk veterans: the IMPROVE study. Impact of Managed Pharmaceutical Care Resource Utilization and Outcomes in Veterans Affairs Medical Centers. Pharmacotherapy (2000) 1.21

Chemotherapy for ovarian cancer--a consensus statement on standard practice. Br J Cancer (1998) 1.19

Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter. Nat Neurosci (2001) 1.17

The identification of Candida albicans strains by restriction fragment length polymorphism analysis of DNA. J Med Vet Mycol (1989) 1.17

Estrogen regulation of specific messinger RNA's in human breast cancer cells. Biochem Biophys Res Commun (1980) 1.16

Cisplatin-cyclophosphamide versus carboplatin-cyclophosphamide in advanced ovarian cancer: a randomized phase III study of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol (1992) 1.15

Attenuation of signaling pathways stimulated by pathologically activated FGF-receptor 2 mutants prevents craniosynostosis. Proc Natl Acad Sci U S A (2006) 1.15

The Oxford hip and knee outcome questionnaires for arthroplasty. J Bone Joint Surg Br (2005) 1.14

Inhibitors of calcium buffering depress evoked transmitter release at the squid giant synapse. J Physiol (1985) 1.13

Cytochrome P-450-dependent 14 alpha-demethylation of lanosterol in Candida albicans. Biochem J (1989) 1.13

Distribution of an estrogen-induced protein with a molecular weight of 24,000 in normal and malignant human tissues and cells. Cancer Res (1983) 1.13

Monovalent and divalent cation permeability and block of neuronal nicotinic receptor channels in rat parasympathetic ganglia. J Gen Physiol (1995) 1.12

DT-diaphorase and cytochrome B5 reductase in human lung and breast tumours. Br J Cancer (1997) 1.12

Phase I study to assess the safety and tolerability of olaparib in combination with bevacizumab in patients with advanced solid tumours. Br J Cancer (2012) 1.11

The sensitivity of human tumour cells to quinone bioreductive drugs: what role for DT-diaphorase? Biochem Pharmacol (1992) 1.10

A new, sensitive polynucleotide probe for distinguishing Candida albicans strains and its use with a computer assisted archiving and pattern comparison system. J Med Vet Mycol (1992) 1.09

Voltage sensitivity of inhibitory postsynaptic current in Aplysia buccal ganglia. Brain Res (1976) 1.09

Phase II studies of BBR3464, a novel tri-nuclear platinum complex, in patients with gastric or gastro-oesophageal adenocarcinoma. Eur J Cancer (2004) 1.08

A phase II trial of marimastat in advanced pancreatic cancer. Br J Cancer (2001) 1.08

Inhibitory postsynaptic currents at Aplysia cholinergic synapses: effects of permeant anions and depressant drugs. Proc R Soc Lond B Biol Sci (1982) 1.08

Loss of CD59 expression in breast tumours correlates with poor survival. J Pathol (2003) 1.07

Phase II trial of vindesine and VP16-213 in the palliation of poor-prognosis patients and elderly patients with small cell lung cancer. Cancer Chemother Pharmacol (1984) 1.07

The effects of knee motion and external loading on the length of the anterior cruciate ligament (ACL): a kinematic study. J Biomech Eng (1991) 1.07

Expression of the Staphylococcus aureus UDP-N-acetylmuramoyl- L-alanyl-D-glutamate:L-lysine ligase in Escherichia coli and effects on peptidoglycan biosynthesis and cell growth. J Bacteriol (1999) 1.07

Prostate adenocarcinoma cells release the novel proinflammatory polypeptide EMAP-II in response to stress. Cancer Res (2000) 1.06

Decay accelerating factor (CD55): a target for cancer vaccines? Cancer Res (1999) 1.06

Are alpha9alpha10 nicotinic acetylcholine receptors a pain target for alpha-conotoxins? Mol Pharmacol (2007) 1.06

Analysis of the frequency of GNAS codon 201 mutations in advanced colorectal cancer. Cancer Genet Cytogenet (2010) 1.05

Relationship between the debrisoquine hydroxylase polymorphism and cancer susceptibility. Carcinogenesis (1992) 1.05

Passive and active membrane properties of isolated rat intracardiac neurons: regulation by H- and M-currents. J Neurophysiol (1997) 1.04

Single amino acid substitutions in alpha-conotoxin PnIA shift selectivity for subtypes of the mammalian neuronal nicotinic acetylcholine receptor. J Biol Chem (1999) 1.04

Advanced gastric cancer: experience in Scotland using 5-fluorouracil, adriamycin and mitomycin-C. Br J Surg (1984) 1.04

Purification and properties of cytochrome P-450-dependent 14 alpha-sterol demethylase from Candida albicans. Biochem J (1989) 1.04

The molecular biology of Huntington's disease. Psychol Med (2001) 1.04

Identification of human cytochromes P-450 analogous to forms induced by phenobarbital and 3-methylcholanthrene in the rat. Biochem J (1985) 1.03

Sex hormones and fungi. Adv Microb Physiol (1993) 1.03

Dexamethasone and high dose metoclopramide: efficacy in controlling cisplatin induced nausea and vomiting. Br Med J (Clin Res Ed) (1984) 1.03

Heterogeneity of nicotinic receptor class and subunit mRNA expression among individual parasympathetic neurons from rat intracardiac ganglia. J Neurosci (1997) 1.03

Resting membrane potential and potassium currents in cultured parasympathetic neurones from rat intracardiac ganglia. J Physiol (1992) 1.03

Slow cycling of unphosphorylated myosin is inhibited by calponin, thus keeping smooth muscle relaxed. Proc Natl Acad Sci U S A (1997) 1.02

Does dexamethasone enhance control of acute cisplatin induced emesis by ondansetron? BMJ (1991) 1.02