Published in J Biol Chem on October 05, 1986
CaM kinase signaling induces cardiac hypertrophy and activates the MEF2 transcription factor in vivo. J Clin Invest (2000) 3.70
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Cyclic GMP-dependent protein kinase phosphorylates phospholamban in isolated sarcoplasmic reticulum from cardiac and smooth muscle. Biochem J (1988) 1.38
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Isoform specificity of the Na/K-ATPase association and regulation by phospholemman. J Biol Chem (2009) 1.23
Phospholamban and its phosphorylated form interact differently with lipid bilayers: a 31P, 2H, and 13C solid-state NMR spectroscopic study. Biochemistry (2006) 1.19
Förster transfer recovery reveals that phospholamban exchanges slowly from pentamers but rapidly from the SERCA regulatory complex. Circ Res (2007) 1.17
Sarcolipin and phospholamban as regulators of cardiac sarcoplasmic reticulum Ca2+ ATPase. J Mol Cell Cardiol (2007) 1.17
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Lipid-mediated folding/unfolding of phospholamban as a regulatory mechanism for the sarcoplasmic reticulum Ca2+-ATPase. J Mol Biol (2011) 1.14
Activating and deactivating roles of lipid bilayers on the Ca(2+)-ATPase/phospholamban complex. Biochemistry (2011) 1.13
The physical mechanism of calcium pump regulation in the heart. Biophys J (1994) 1.13
The structural basis for phospholamban inhibition of the calcium pump in sarcoplasmic reticulum. J Biol Chem (2013) 1.06
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Functional and physical competition between phospholamban and its mutants provides insight into the molecular mechanism of gene therapy for heart failure. Biochem Biophys Res Commun (2011) 1.03
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Side chain and backbone dynamics of phospholamban in phospholipid bilayers utilizing 2H and 15N solid-state NMR spectroscopy. Biochemistry (2007) 1.01
Phospholamban remains associated with the Ca2+- and Mg2+-dependent ATPase following phosphorylation by cAMP-dependent protein kinase. Biochem J (2000) 1.01
High-throughput FRET assay yields allosteric SERCA activators. J Biomol Screen (2012) 1.01
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Investigating structural changes in the lipid bilayer upon insertion of the transmembrane domain of the membrane-bound protein phospholamban utilizing 31P and 2H solid-state NMR spectroscopy. Biophys J (2004) 0.99
Translation of Ser16 and Thr17 phosphorylation of phospholamban into Ca 2+-pump stimulation. Biochem J (1996) 0.98
Hydrophobic imbalance in the cytoplasmic domain of phospholamban is a determinant for lethal dilated cardiomyopathy. J Biol Chem (2012) 0.96
Phospholamban mutants compete with wild type for SERCA binding in living cells. Biochem Biophys Res Commun (2012) 0.96
Sarco(endo)plasmic reticulum calcium ATPase (SERCA) inhibition by sarcolipin is encoded in its luminal tail. J Biol Chem (2013) 0.96
Catecholamine-independent heart rate increases require Ca2+/calmodulin-dependent protein kinase II. Circ Arrhythm Electrophysiol (2011) 0.95
Beyond the cardiac myofilament: hypertrophic cardiomyopathy- associated mutations in genes that encode calcium-handling proteins. Curr Mol Med (2012) 0.94
Identification of biochemical adaptations in hyper- or hypocontractile hearts from phospholamban mutant mice by expression proteomics. Proc Natl Acad Sci U S A (2004) 0.92
Lethal, hereditary mutants of phospholamban elude phosphorylation by protein kinase A. J Biol Chem (2012) 0.92
Regulation of the cardiac sodium pump. Cell Mol Life Sci (2012) 0.92
Phospholamban overexpression in transgenic rabbits. Transgenic Res (2007) 0.91
Role of sodium and calcium dysregulation in tachyarrhythmias in sudden cardiac death. Circ Res (2015) 0.91
Computational design of a water-soluble analog of phospholamban. Protein Sci (2003) 0.91
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Calcium/calmodulin-dependent protein kinase II: role in learning and memory. Mol Cell Biochem (1993) 0.89
Epac1-dependent phospholamban phosphorylation mediates the cardiac response to stresses. J Clin Invest (2014) 0.89
Accurate quantitation of phospholamban phosphorylation by immunoblot. Anal Biochem (2012) 0.89
cDNAs for the postsynaptic 43-kDa protein of Torpedo electric organ encode two proteins with different carboxyl termini. Proc Natl Acad Sci U S A (1987) 0.88
Depletion of Ca2+ from the sarcoplasmic reticulum of cardiac muscle prompts phosphorylation of phospholamban to stimulate store refilling. Proc Natl Acad Sci U S A (1998) 0.86
cDNA cloning and sequencing of phospholamban from pig stomach smooth muscle. Biochem J (1989) 0.85
Sites of in vivo phosphorylation of vesicular stomatitis virus matrix protein. J Virol (1992) 0.84
Ser16-, but not Thr17-phosphorylation of phospholamban influences frequency-dependent force generation in human myocardium. Pflugers Arch (2003) 0.83
CaMKIIδC slows [Ca]i decline in cardiac myocytes by promoting Ca sparks. Biophys J (2012) 0.82
Increased Ca2+ sensitivity and protein expression of SERCA 2a in situations of chronic beta3-adrenoceptor deficiency. Pflugers Arch (2006) 0.82
Superior calcium homeostasis of extraocular muscles. Exp Eye Res (2010) 0.81
Synthetic phosphopeptides enable quantitation of the content and function of the four phosphorylation states of phospholamban in cardiac muscle. J Biol Chem (2014) 0.79
Rheostatic Regulation of the SERCA/Phospholamban Membrane Protein Complex Using Non-Coding RNA and Single-Stranded DNA oligonucleotides. Sci Rep (2015) 0.79
Structural basis for phosphorylation and lysine acetylation cross-talk in a kinase motif associated with myocardial ischemia and cardioprotection. J Biol Chem (2014) 0.78
Protein kinase C modulation of the regulation of sarcoplasmic reticular function by protein kinase A-mediated phospholamban phosphorylation in diabetic rats. Br J Pharmacol (2003) 0.78
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Anti-phospholamban and protein kinase A alter the Ca2+ sensitivity and maximum velocity of Ca2+ uptake by the cardiac sarcoplasmic reticulum. Biochem J (1998) 0.78
Endothelin-1 prolongs intracellular calcium transient decay in neonatal rat cardiac myocytes. Heart Vessels (2011) 0.77
The role of CaMKII in diabetic heart dysfunction. Heart Fail Rev (2015) 0.77
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Disruption of sarcoendoplasmic reticulum calcium ATPase function in Drosophila leads to cardiac dysfunction. PLoS One (2013) 0.77
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The expression of canine cardiac phospholamban in heterologous systems. Biochem J (1989) 0.76
Synergistic effects between phosphorylation of phospholamban and troponin I promote relaxation at higher heart rate. J Biomed Biotechnol (2011) 0.76
Reversal of Phospholamban Inhibition of the Sarco(endo)plasmic Reticulum Ca2+-ATPase (SERCA) Using Short, Protein-interacting RNAs and Oligonucleotide Analogs. J Biol Chem (2016) 0.75
Cardiac Calcium ATPase Dimerization Measured by Cross-Linking and Fluorescence Energy Transfer. Biophys J (2016) 0.75
Regulation of the sarcoplasmic reticulum calcium pump by divergent phospholamban isoforms in zebrafish. J Biol Chem (2015) 0.75
Vascular CaMKII: heart and brain in your arteries. Am J Physiol Cell Physiol (2016) 0.75
Expression of calcium-buffering proteins in rat intrinsic laryngeal muscles. Physiol Rep (2015) 0.75
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Complex formation between junctin, triadin, calsequestrin, and the ryanodine receptor. Proteins of the cardiac junctional sarcoplasmic reticulum membrane. J Biol Chem (1997) 3.50
Phospholamban: protein structure, mechanism of action, and role in cardiac function. Physiol Rev (1998) 3.23
Unique phosphorylation site on the cardiac ryanodine receptor regulates calcium channel activity. J Biol Chem (1991) 3.10
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The primary structure of actin from rabbit skeletal muscle. Completion and analysis of the amino acid sequence. J Biol Chem (1975) 2.84
A leucine zipper stabilizes the pentameric membrane domain of phospholamban and forms a coiled-coil pore structure. J Biol Chem (1996) 2.13
beta-Adrenergic stimulation of phospholamban phosphorylation and Ca2+-ATPase activity in guinea pig ventricles. J Biol Chem (1983) 2.07
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Purification and complete sequence determination of the major plasma membrane substrate for cAMP-dependent protein kinase and protein kinase C in myocardium. J Biol Chem (1991) 1.92
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Ca2+ binding effects on protein conformation and protein interactions of canine cardiac calsequestrin. J Biol Chem (1988) 1.90
Phospholamban phosphorylation in intact ventricles. Phosphorylation of serine 16 and threonine 17 in response to beta-adrenergic stimulation. J Biol Chem (1989) 1.88
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Complete amino acid sequence of canine cardiac calsequestrin deduced by cDNA cloning. J Biol Chem (1988) 1.75
Phospholemman expression induces a hyperpolarization-activated chloride current in Xenopus oocytes. J Biol Chem (1992) 1.69
A fluorescent probe study of Ca2+ binding to the Ca2+-specific sites of cardiac troponin and troponin C. J Biol Chem (1980) 1.65
Mutation and phosphorylation change the oligomeric structure of phospholamban in lipid bilayers. Biochemistry (1997) 1.63
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Increased expression of cardiac phosphatases in patients with end-stage heart failure. J Mol Cell Cardiol (1997) 1.60
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Identification of the major protein phosphatases in mammalian cardiac muscle which dephosphorylate phospholamban. Eur J Biochem (1991) 1.56
Defective beta-adrenergic receptor signaling precedes the development of dilated cardiomyopathy in transgenic mice with calsequestrin overexpression. J Biol Chem (1999) 1.56
Biochemical evidence for functional heterogeneity of cardiac sarcoplasmic reticulum vesicles. J Biol Chem (1981) 1.54
Rapid purification of calsequestrin from cardiac and skeletal muscle sarcoplasmic reticulum vesicles by Ca2+-dependent elution from phenyl-sepharose. J Biol Chem (1983) 1.53
Phospholamban forms Ca2+-selective channels in lipid bilayers. J Biol Chem (1988) 1.52
Localization and characterization of the calsequestrin-binding domain of triadin 1. Evidence for a charged beta-strand in mediating the protein-protein interaction. J Biol Chem (2000) 1.51
Depolymerization of phospholamban in the presence of calcium pump: a fluorescence energy transfer study. Biochemistry (1999) 1.50
A fluorescence energy transfer method for analyzing protein oligomeric structure: application to phospholamban. Biophys J (1999) 1.50
Cellular mechanisms of altered contractility in the hypertrophied heart: big hearts, big sparks. Circ Res (1999) 1.49
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Identification of triadin 1 as the predominant triadin isoform expressed in mammalian myocardium. J Biol Chem (1999) 1.48
Mat-8, a novel phospholemman-like protein expressed in human breast tumors, induces a chloride conductance in Xenopus oocytes. J Biol Chem (1995) 1.47
Molecular cloning and immunological characterization of the gamma polypeptide, a small protein associated with the Na,K-ATPase. J Cell Biol (1993) 1.46
Phosphorylation-induced mobility shift in phospholamban in sodium dodecyl sulfate-polyacrylamide gels. Evidence for a protein structure consisting of multiple identical phosphorylatable subunits. J Biol Chem (1984) 1.45
Unitary anion currents through phospholemman channel molecules. Nature (1995) 1.43
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Isoproterenol-induced phosphorylation of a 15-kilodalton sarcolemmal protein in intact myocardium. J Biol Chem (1985) 1.38
Fetal grasping of the umbilical cord with simultaneous fetal heart rate monitoring. Am J Obstet Gynecol (1994) 1.37
Secondary structure and orientation of phospholamban reconstituted in supported bilayers from polarized attenuated total reflection FTIR spectroscopy. Biochemistry (1995) 1.35
Biochemical characterization and molecular cloning of cardiac triadin. J Biol Chem (1996) 1.33
Functional Co-expression of the canine cardiac Ca2+ pump and phospholamban in Spodoptera frugiperda (Sf21) cells reveals new insights on ATPase regulation. J Biol Chem (1997) 1.33
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Comparative studies of cardiac and skeletal sarcoplasmic reticulum ATPases. Effect of a phospholamban antibody on enzyme activation by Ca2+. J Biol Chem (1993) 1.32
Comparison of the actin binding and filament formation properties of phosphorylated and dephosphorylated Acanthamoeba myosin II. Biochemistry (1982) 1.29
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Homology of myosin DTNB light chain with alkali light chains, troponin C and parvalbumin. Nature (1976) 1.28
Separation of vesicles of cardiac sarcolemma from vesicles of cardiac sarcoplasmic reticulum. Comparative biochemical analysis of component activities. J Biol Chem (1979) 1.27
Localization of the three phosphorylation sites on each heavy chain of Acanthamoeba myosin II to a segment at the end of the tail. J Biol Chem (1982) 1.26
Unmasking effect of alamethicin on the (Na+,K+)-ATPase, beta-adrenergic receptor-coupled adenylate cyclase, and cAMP-dependent protein kinase activities of cardiac sarcolemmal vesicles. J Biol Chem (1980) 1.26
High molecular weight proteins in cardiac and skeletal muscle junctional sarcoplasmic reticulum vesicles bind calmodulin, are phosphorylated, and are degraded by Ca2+-activated protease. J Biol Chem (1984) 1.26
Purification and characterization of actin-activatable, Ca2+-sensitive myosin II from Acanthamoeba. J Biol Chem (1981) 1.24
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Purification and analysis of colonization factor antigen I, coli surface antigen 1, and coli surface antigen 3 fimbriae from enterotoxigenic Escherichia coli. J Bacteriol (1989) 1.19
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Cysteine reactivity and oligomeric structures of phospholamban and its mutants. Biochemistry (1998) 1.14
Ca2+ stimulates the Mg2(+)-ATPase activity of brush border myosin I with three or four calmodulin light chains but inhibits with less than two bound. J Biol Chem (1991) 1.14
Rapid preparation of canine cardiac sarcolemmal vesicles by sucrose flotation. Methods Enzymol (1988) 1.13
The physical mechanism of calcium pump regulation in the heart. Biophys J (1994) 1.13
Reexamination of the role of the leucine/isoleucine zipper residues of phospholamban in inhibition of the Ca2+ pump of cardiac sarcoplasmic reticulum. J Biol Chem (2000) 1.13
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Immunoelectron microscopical localization of phospholamban in adult canine ventricular muscle. J Cell Biol (1987) 1.09
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Secondary structure of detergent-solubilized phospholamban, a phosphorylatable, oligomeric protein of cardiac sarcoplasmic reticulum. Biochim Biophys Acta (1989) 1.06
Tryptic and chymotryptic cleavage sites in sequence of alpha-subunit of (Na+ + K+)-ATPase from outer medulla of mammalian kidney. Biochim Biophys Acta (1986) 1.05
Enhanced myocardial relaxation in vivo in transgenic mice overexpressing the beta2-adrenergic receptor is associated with reduced phospholamban protein. J Clin Invest (1996) 1.05
Characterization of the intrinsic cAMP-dependent protein kinase activity and endogenous substrates in highly purified cardiac sarcolemmal vesicles. J Biol Chem (1982) 1.04
Smooth-muscle endoplasmic reticulum contains a cardiac-like form of calsequestrin. Biochim Biophys Acta (1987) 1.04
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