Published in Nucleic Acids Res on October 10, 1986
Distribution of repetitive DNA sequences in eubacteria and application to fingerprinting of bacterial genomes. Nucleic Acids Res (1991) 19.89
Characterization of universal small-subunit rRNA hybridization probes for quantitative molecular microbial ecology studies. Appl Environ Microbiol (1996) 5.99
5-Nitroindole as an universal base analogue. Nucleic Acids Res (1994) 2.78
Detection of erythromycin resistance by the polymerase chain reaction using primers in conserved regions of erm rRNA methylase genes. Antimicrob Agents Chemother (1990) 2.49
Excision of hypoxanthine from DNA containing dIMP residues by the Escherichia coli, yeast, rat, and human alkylpurine DNA glycosylases. Proc Natl Acad Sci U S A (1994) 2.15
M.HhaI binds tightly to substrates containing mismatches at the target base. Nucleic Acids Res (1995) 1.91
Mutagenic potentials of damaged nucleic acids produced by reactive oxygen/nitrogen species: approaches using synthetic oligonucleotides and nucleotides: survey and summary. Nucleic Acids Res (2003) 1.73
Studies on the base pairing properties of deoxyinosine by solid phase hybridisation to oligonucleotides. Nucleic Acids Res (1994) 1.72
Survey and summary: The applications of universal DNA base analogues. Nucleic Acids Res (2001) 1.62
Nearest-neighbor thermodynamics of deoxyinosine pairs in DNA duplexes. Nucleic Acids Res (2005) 1.33
Selective and Stable DNA Base Pairing without Hydrogen Bonds. J Am Chem Soc (1998) 1.24
5-Fluorodeoxyuridine as an alternative to the synthesis of mixed hybridization probes for the detection of specific gene sequences. Proc Natl Acad Sci U S A (1988) 1.23
Synthesis of oligodeoxyribonucleotides containing degenerate bases and their use as primers in the polymerase chain reaction. Nucleic Acids Res (1992) 1.16
Hybridization and dissociation rates of phosphodiester or modified oligodeoxynucleotides with RNA at near-physiological conditions. Nucleic Acids Res (1991) 1.14
Detection of aac(6')-I genes in amikacin-resistant Acinetobacter spp. by PCR. Antimicrob Agents Chemother (1994) 1.10
Study of heterogeneity of chloramphenicol acetyltransferase (CAT) genes in streptococci and enterococci by polymerase chain reaction: characterization of a new CAT determinant. Antimicrob Agents Chemother (1993) 1.08
Polymerase recognition of synthetic oligodeoxyribonucleotides incorporating degenerate pyrimidine and purine bases. Proc Natl Acad Sci U S A (1998) 1.07
Unlocking hidden genomic sequence. Nucleic Acids Res (2004) 1.04
The synthesis and stability of oligodeoxyribonucleotides containing the deoxyadenosine mimic 1-(2'-deoxy-beta-D-ribofuranosyl)imidazole-4-carboxamide. Nucleic Acids Res (1997) 1.01
NMR studies for identification of dI:dG mismatch base-pairing structure in DNA. Nucleic Acids Res (1991) 1.00
Sequence saturation mutagenesis (SeSaM): a novel method for directed evolution. Nucleic Acids Res (2004) 0.97
DNA containing the base analogue 2-aminoadenine: preparation, use as hybridization probes and cleavage by restriction endonucleases. Nucleic Acids Res (1988) 0.97
The stability of oligodeoxyribonucleotide duplexes containing degenerate bases. Nucleic Acids Res (1987) 0.96
Role of the 2-amino group of purines during dNTP polymerization by human DNA polymerase alpha. Biochemistry (2009) 0.93
An acyclic 5-nitroindazole nucleoside analogue as ambiguous nucleoside. Nucleic Acids Res (1995) 0.92
The N(8)-(2'-deoxyribofuranoside) of 8-aza-7-deazaadenine: a universal nucleoside forming specific hydrogen bonds with the four canonical DNA constituents. Nucleic Acids Res (2000) 0.91
Template directed incorporation of nucleotide mixtures using azole-nucleobase analogs. Nucleic Acids Res (1997) 0.89
Identification of Escherichia coli mismatch-specific uracil DNA glycosylase as a robust xanthine DNA glycosylase. J Biol Chem (2010) 0.87
Oligonucleotides containing fluorescent 2'-deoxyisoinosine: solid-phase synthesis and duplex stability. Nucleic Acids Res (1995) 0.83
Molecular characterization of resistance-nodulation-division transporters from solvent- and drug-resistant bacteria in petroleum-contaminated soil. Appl Environ Microbiol (2005) 0.82
Use of base modifications in primers and amplicons to improve nucleic acids detection in the real-time snake polymerase chain reaction. Assay Drug Dev Technol (2010) 0.77
The loss of a hydrogen bond: Thermodynamic contributions of a non-standard nucleotide. Nucleic Acids Res (2017) 0.75
Chemical and structural effects of base modifications in messenger RNA. Nature (2017) 0.75
Introduction of mismatches in a random shRNA-encoding library improves potency for phenotypic selection. PLoS One (2014) 0.75
DNA sequence analysis: a general, simple and rapid method for sequencing large oligodeoxyribonucleotide fragments by mapping. Nucleic Acids Res (1974) 19.42
Stability of ribonucleic acid double-stranded helices. J Mol Biol (1974) 16.35
Codon--anticodon pairing: the wobble hypothesis. J Mol Biol (1966) 14.75
Base-base mismatches. Thermodynamics of double helix formation for dCA3XA3G + dCT3YT3G (X, Y = A,C,G,T). Nucleic Acids Res (1985) 7.19
Physical and chemical characterization of two- and three-stranded adenine-thymine and adenine-uracil homopolymer complexes. J Mol Biol (1966) 5.83
The use of nuclease P1 in sequence analysis of end group labeled RNA. Nucleic Acids Res (1977) 4.67
An alternative approach to deoxyoligonucleotides as hybridization probes by insertion of deoxyinosine at ambiguous codon positions. J Biol Chem (1985) 4.44
Base pairing involving deoxyinosine: implications for probe design. Nucleic Acids Res (1985) 4.41
Solid-phase synthesis of polynucleotides. IV. Usage of polystyrene resins for the synthesis of polydeoxyribonucleotides by the phosphostriester method. Nucleic Acids Res (1980) 3.59
Detection of a guanine X adenine base pair in a decadeoxyribonucleotide by proton magnetic resonance spectroscopy. Proc Natl Acad Sci U S A (1983) 2.85
Self-complementary oligoribonucleotides: adenylic acid-uridylic acid block copolymers. J Mol Biol (1971) 2.78
Molecular structure of the G.A base pair in DNA and its implications for the mechanism of transversion mutations. Proc Natl Acad Sci U S A (1986) 2.46
Deoxyadenosine-deoxycytidine pairing in the d(C-G-C-G-A-A-T-T-C-A-C-G) duplex: conformation and dynamics at and adjacent to the dA X dC mismatch site. Biochemistry (1984) 1.98
Synthetic polynucleotides. Prog Nucleic Acid Res Mol Biol (1967) 1.79
Deoxyribonucleic acids (DNA) and related compounds. XIII. Synthesis of DNA duplexes containing a ribosome binding site. Chem Pharm Bull (Tokyo) (1985) 0.97
The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers. Cell (1996) 15.19
The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta. Nature (1999) 10.87
Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair. Mol Cell (1998) 9.41
A perpendicular-anisotropy CoFeB-MgO magnetic tunnel junction. Nat Mater (2010) 7.78
Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature (1994) 6.06
Quantitative assessment of DNA microarrays--comparison with Northern blot analyses. Genomics (2001) 4.56
An alternative approach to deoxyoligonucleotides as hybridization probes by insertion of deoxyinosine at ambiguous codon positions. J Biol Chem (1985) 4.44
An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin. Cell (2001) 4.41
N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases. EMBO J (1996) 4.31
Three-dimensional structure of an oncogene protein: catalytic domain of human c-H-ras p21. Science (1988) 3.99
Congenital stationary night blindness with negative electroretinogram. A new classification. Arch Ophthalmol (1986) 3.90
Studies on polynucleotides. LI. Syntheses of the 64 possible ribotrinucleotides derived from the four major ribomononucleotides. J Am Chem Soc (1966) 3.83
Studies on polynucleotides, XLIX. Stimulation of the binding of aminoacyl-sRNA's to ribosomes by ribotrinucleotides and a survey of codon assignments for 20 amino acids. Proc Natl Acad Sci U S A (1965) 3.71
A simple method to estimate populational 24-h urinary sodium and potassium excretion using a casual urine specimen. J Hum Hypertens (2002) 3.67
The M1- and M2-type isozymes of rat pyruvate kinase are produced from the same gene by alternative RNA splicing. J Biol Chem (1986) 3.64
A blocked structure at the 5' terminus of mRNA from cytoplasmic polyhedrosis virus. Nature (1975) 3.59
Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues. Nature (1987) 3.55
Mechanisms of accurate translesion synthesis by human DNA polymerase eta. EMBO J (2000) 3.46
Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity. EMBO J (1999) 3.31
Novel immunosuppressive agent, FK506. In vitro effects on the cloned T cell activation. J Immunol (1987) 3.30
Synthesis and hybridization studies on two complementary nona(2'-O-methyl)ribonucleotides. Nucleic Acids Res (1987) 3.24
Molecular cloning of the human cholecystokinin gene by use of a synthetic probe containing deoxyinosine. Proc Natl Acad Sci U S A (1985) 3.01
Age related changes in 5-methylcytosine content in human peripheral leukocytes and placentas: an HPLC-based study. Ann Hum Genet (2004) 2.95
Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain. Proc Natl Acad Sci U S A (1986) 2.83
Treatment of dry eye by autologous serum application in Sjögren's syndrome. Br J Ophthalmol (1999) 2.77
Numbering system for the hammerhead. Nucleic Acids Res (1992) 2.74
Sequence-dependent hydrolysis of RNA using modified oligonucleotide splints and RNase H. FEBS Lett (1987) 2.74
5'-Terminal nucleotide sequences of the double-stranded RNA of silkworm cytoplasmic polyhedrosis virus. J Mol Biol (1974) 2.71
A multistep damage recognition mechanism for global genomic nucleotide excision repair. Genes Dev (2001) 2.59
Site-directed cleavage of RNA. Nucleic Acids Res (1987) 2.53
Total synthesis of the gene for an alanine transfer ribonucleic acid from yeast. Nature (1970) 2.51
Immunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitro. J Biol Chem (1999) 2.49
Construction of a series of several self-cleaving RNA duplexes using synthetic 21-mers. FEBS Lett (1988) 2.42
Flt-1, vascular endothelial growth factor receptor 1, is a novel cell surface marker for the lineage of monocyte-macrophages in humans. Blood (2001) 2.39
Error-prone bypass of certain DNA lesions by the human DNA polymerase kappa. Genes Dev (2000) 2.38
Recanalization after coil embolotherapy of pulmonary arteriovenous malformations: study of long-term outcome and mechanism for recanalization. AJR Am J Roentgenol (1998) 2.38
Divergence and convergence of TGF-beta/BMP signaling. J Cell Physiol (2001) 2.37
The FHIT gene 3p14.2 is abnormal in lung cancer. Cell (1996) 2.36
Atomic model of a pyrimidine dimer excision repair enzyme complexed with a DNA substrate: structural basis for damaged DNA recognition. Cell (1995) 2.36
c-Ski acts as a transcriptional co-repressor in transforming growth factor-beta signaling through interaction with smads. J Biol Chem (1999) 2.32
Joining of ribooligonucleotides with T4 RNA ligase and identification of the oligonucleotide-adenylate intermediate. Nucleic Acids Res (1976) 2.31
Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): an archaeal DinB-like DNA polymerase with lesion-bypass properties akin to eukaryotic poleta. Nucleic Acids Res (2001) 2.29
The L- and R-type isozymes of rat pyruvate kinase are produced from a single gene by use of different promoters. J Biol Chem (1987) 2.25
A modified structure at the 5'-terminus of mRNA of vaccinia virus. FEBS Lett (1975) 2.23
Sugar-sweetened beverage and diet soda consumption and the 7-year risk for type 2 diabetes mellitus in middle-aged Japanese men. Eur J Nutr (2013) 2.20
Smad proteins exist as monomers in vivo and undergo homo- and hetero-oligomerization upon activation by serine/threonine kinase receptors. EMBO J (1998) 2.20
Role of the extra G-C pair at the end of the acceptor stem of tRNA(His) in aminoacylation. Nucleic Acids Res (1989) 2.18
Most compact hairpin-turn structure exerted by a short DNA fragment, d(GCGAAGC) in solution: an extraordinarily stable structure resistant to nucleases and heat. Nucleic Acids Res (1994) 2.14
Absorption, tissue concentration, and organ distribution of cefazolin. Antimicrob Agents Chemother (Bethesda) (1970) 2.13
Identification of the amino acid residues involved in an active site of Escherichia coli ribonuclease H by site-directed mutagenesis. J Biol Chem (1990) 2.12
The 5'-terminal nucleotide sequences of the double-stranded RNA of human reovirus. Proc Natl Acad Sci U S A (1974) 2.08
Effects of phosphorothioate and 2-amino groups in hammerhead ribozymes on cleavage rates and Mg2+ binding. Biochemistry (1991) 2.08
Genetic variants of IL-13 signalling and human asthma and atopy. Hum Mol Genet (2000) 2.08
Detection of cancer micrometastases in lymph nodes by reverse transcriptase-polymerase chain reaction. Cancer Res (1995) 2.07
Cleavage of specific sites of RNA by designed ribozymes. FEBS Lett (1988) 2.05
NMR studies of a DNA containing 8-hydroxydeoxyguanosine. Nucleic Acids Res (1991) 2.03
Synthesis and characterization of a substrate for T4 endonuclease V containing a phosphorodithioate linkage at the thymine dimer site. Nucleic Acids Res (1990) 2.03
Magnifying endoscopy, stereoscopic microscopy, and the microvascular architecture of superficial esophageal carcinoma. Endoscopy (2002) 2.01
DNA damage-inducible gene p33ING2 negatively regulates cell proliferation through acetylation of p53. Proc Natl Acad Sci U S A (2001) 2.00
Identification of human MutY homolog (hMYH) as a repair enzyme for 2-hydroxyadenine in DNA and detection of multiple forms of hMYH located in nuclei and mitochondria. Nucleic Acids Res (2000) 2.00
Structure-function relationship of the eukaryotic DNA replication factor, proliferating cell nuclear antigen. J Biol Chem (1995) 1.99
Angiopoietin-2 is related to tumor angiogenesis in gastric carcinoma: possible in vivo regulation via induction of proteases. Cancer Res (2001) 1.98
Extraordinarily stable mini-hairpins: electrophoretical and thermal properties of the various sequence variants of d(GCGAAAGC) and their effect on DNA sequencing. Nucleic Acids Res (1992) 1.94
A 2-thiouridine derivative in tRNAGlu is a positive determinant for aminoacylation by Escherichia coli glutamyl-tRNA synthetase. Biochemistry (1993) 1.92
Writing waveguides in glass with a femtosecond laser. Opt Lett (1996) 1.91
Studies on polynucleotides. XCVI. Repair replications of short synthetic DNA's as catalyzed by DNA polymerases. J Mol Biol (1971) 1.87
Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells. J Biol Chem (1998) 1.87
WFS1 (Wolfram syndrome 1) gene product: predominant subcellular localization to endoplasmic reticulum in cultured cells and neuronal expression in rat brain. Hum Mol Genet (2001) 1.86
Characterization of DNA polymerase from Pyrococcus sp. strain KOD1 and its application to PCR. Appl Environ Microbiol (1997) 1.86
Novel Pseudomonas product stimulates interleukin-8 production in airway epithelial cells in vitro. J Clin Invest (1994) 1.85
Constitutive activation of NF-kappa B is essential for transformation of rat fibroblasts by the human T-cell leukemia virus type I Tax protein. EMBO J (1996) 1.85
Comparative studies with various substrains of Mycobacterium bovis BCG on the production of an antigenic protein, MPB70. Infect Immun (1983) 1.83
Activation of eotaxin gene transcription by NF-kappa B and STAT6 in human airway epithelial cells. J Immunol (1999) 1.83
Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation. Nat Med (1999) 1.82
Essential structure of E. coli promoter: effect of spacer length between the two consensus sequences on promoter function. Nucleic Acids Res (1983) 1.80
Frequent somatic mutation of the MTS1/CDK4I (multiple tumor suppressor/cyclin-dependent kinase 4 inhibitor) gene in esophageal squamous cell carcinoma. Cancer Res (1994) 1.80
Structure and expression of the human FHIT gene in normal and tumor cells. Cancer Res (1997) 1.76
Recent developments in the chemical synthesis of polynucleotides. Nucleic Acids Res (1982) 1.76
Mutations in the sulonylurea receptor gene are associated with familial hyperinsulinism in Ashkenazi Jews. Hum Mol Genet (1996) 1.76
Dysfunction of human Rad18 results in defective postreplication repair and hypersensitivity to multiple mutagens. Proc Natl Acad Sci U S A (2000) 1.74
Exercise-induced U-wave alterations as a marker of well-developed and well-functioning collateral vessels in patients with effort angina. J Am Coll Cardiol (2000) 1.73