Published in Science on August 03, 1979
Primary structure of the ompF gene that codes for a major outer membrane protein of Escherichia coli K-12. Nucleic Acids Res (1982) 3.24
Pseudomonas aeruginosa infection in cystic fibrosis: nucleotide sequence and transcriptional regulation of the algD gene. Nucleic Acids Res (1987) 2.63
DNA sequence of the Serratia marcescens lipoprotein gene. Proc Natl Acad Sci U S A (1980) 2.14
Regulation of promoter selection by the bacteriophage T7 RNA polymerase in vitro. Nucleic Acids Res (1980) 1.52
Identification, nucleotide sequence and expression of the regulatory region of the histidine operon of Escherichia coli K-12. Nucleic Acids Res (1981) 1.41
Construction of bacteriophage T7 late promoters with point mutations and characterization by in vitro transcription properties. Nucleic Acids Res (1987) 1.31
Structural properties of promoters: similarities and differences between prokaryotes and eukaryotes. Nucleic Acids Res (2005) 1.30
A novel method for prokaryotic promoter prediction based on DNA stability. BMC Bioinformatics (2005) 1.28
Transcription of the tRNA-tufB operon of Escherichia coli: activation, termination and antitermination. Nucleic Acids Res (1987) 1.13
High A + T content conserved in DNA sequences upstream of leuABCD in Escherichia coli and Salmonella typhimurium. J Bacteriol (1986) 1.13
Transcriptional analysis of the promoter region of the Pseudomonas putida branched-chain keto acid dehydrogenase operon. J Bacteriol (1990) 0.96
Human Pol II promoter recognition based on primary sequences and free energy of dinucleotides. BMC Bioinformatics (2008) 0.87
Distinguishing between productive and abortive promoters using a random forest classifier in Mycoplasma pneumoniae. Nucleic Acids Res (2015) 0.77
Mapping of deletions and substitutions in heteroduplex DNA molecules of bacteriophage lambda by electron microscopy. Science (1969) 5.54
Nomenclature of transposable elements in prokaryotes. Gene (1979) 4.13
Microbial Selection. Science (1952) 4.08
Physicochemical properties of complexes between deoxyribonucleic acid and antibiotics which affect ribonucleic acid synthesis (actinomycin, daunomycin, cinerubin, nogalamycin, chormomycin, mithramycin, and olivomycin). Biochemistry (1966) 4.06
Electron microscopy of polar insertions in the lac operon of Escherichia coli. Mol Gen Genet (1972) 3.85
Escherichia coli genome targeting, I. Cre-lox-mediated in vitro generation of ori- plasmids and their in vivo chromosomal integration and retrieval. Gene (1994) 3.84
In vivo excision and amplification of large segments of the Escherichia coli genome. Nucleic Acids Res (1994) 3.61
Polar mutations in lac, gal and phage lambda consist of a few IS-DNA sequences inserted with either orientation. Mol Gen Genet (1972) 3.59
A comprehensive molecular map of bacteriophage lambda. Gene (1979) 3.46
Deletions and insertions in the immunity region of coliphage lambda: revised measurement of the promoter-startpoint distance. Virology (1974) 3.44
Asymmetric distribution of the transcribing regions on the complementary strands of coliphage lambda DNA. Proc Natl Acad Sci U S A (1967) 2.70
A routine method for protein-free spreading of double- and single-stranded nucleic acid molecules. Proc Natl Acad Sci U S A (1975) 2.43
Infectious and noninfectious recombinant clones of the provirus of SNV differ in cellular DNA and are apparently the same in viral DNA. Cell (1980) 2.35
Nomenclature of transposable elements in prokaryotes. Plasmid (1979) 2.17
Patterns of interaction between polyribonucleotides and individual DNA strands derived from several vertebrates, bacteria and bacteriophages. J Mol Biol (1966) 2.13
Electron micrographic maps of deletions and substitutions in the genomes of transducing coliphages lambda dg and lambda bio. Virology (1969) 2.04
Coliphage lambdanutL-: a unique class of mutants defective in the site of gene N product utilization for antitermination of leftward transcription. J Mol Biol (1978) 2.00
Pyrimidine clusters on the transcribing strand of DNA and their possible role in the initiation of RNA synthesis. Cold Spring Harb Symp Quant Biol (1966) 1.96
A simple method for identifying the palindromic sequences recognized by restriction endonucleases: the nucleotide sequence of the AvaII site. Gene (1978) 1.91
Universal restriction endonucleases: designing novel cleavage specificities by combining adapter oligodeoxynucleotide and enzyme moieties. Gene (1985) 1.85
Controls and polarity of transcription during bacteriophage T4 development. J Mol Biol (1971) 1.77
Fractionation of the complementary strands of coliphage T4 DNA based on the asymmetric distribution of the poly U and poly U,G binding sites. Virology (1968) 1.75
Control of short leftward transcripts from the immunity and ori regions in induced coliphage lambda. Mol Gen Genet (1973) 1.74
Cleaving yeast and Escherichia coli genomes at a single site. Science (1990) 1.70
Patterns of convergent and overlapping transcription within the b2 region of coliphage lambda. Virology (1969) 1.58
Suppression of RNA precipitation during Cs2SO4 density gradient centrifugation. Biochem Biophys Res Commun (1966) 1.54
Orientation of transcription of the lac operon and its repressor gene in Escherichia coli. J Mol Biol (1969) 1.52
Packaging of plasmid DNA containing the cohesive ends of coliphage lambda. Gene (1980) 1.45
GENETIC INTERACTION AMONG STREPTOMYCETES: HETEROKARYOSIS AND SYNKARYOSIS. Proc Natl Acad Sci U S A (1957) 1.43
Insertion sequence IS2 associated with int-constitutive mutants of bacteriophage lambda. Gene (1977) 1.43
Orientation and control of transcription in E. coli phage lambda. Nature (1969) 1.43
Physical and biological consequences of interactions between integration host factor (IHF) and coliphage lambda late p'R promoter and its mutants. Gene (1989) 1.42
Purification and characterization of an isoschizomer of Asu II from Clostridium sporogenes. Nucleic Acids Res (1989) 1.40
Control of cloned gene expression by promoter inversion in vivo: construction of improved vectors with a multiple cloning site and the Ptac promoter. Gene (1987) 1.39
DNA base composition of Neisseria, Moraxella, and Acinetobacter, as determined by measurement of buoyant density in CsCl gradients. Can J Microbiol (1969) 1.37
Cleaving DNA at any predetermined site with adapter-primers and class-IIS restriction enzymes. Science (1988) 1.37
Preparing and using agarose microbeads. Methods Enzymol (1992) 1.34
Aminoglycoside-modifying enzymes of Staphylococcus aureus; expression in Escherichia coli. Gene (1980) 1.31
Regulation of integration by coliphage lambda: activation of int transcription by the cII and cIII proteins. Virology (1979) 1.29
Distance from a promoter mutation to an RNA synthesis startpoint on bacteriophage lambda DNA. Nat New Biol (1972) 1.26
Transcriptional controls in developing bacteriophages. J Cell Physiol (1969) 1.25
Initiation and patterns of transcription during phage development. Proc Can Cancer Conf (1969) 1.22
Orientation of transcription for the galactose operon as determined by hybridization of gal mRNA with the separated DNA strands of coliphages lambda-dg. J Mol Biol (1968) 1.21
Controls of rightward transcription in coliphage lambda. J Mol Biol (1970) 1.19
RecA-AC: single-site cleavage of plasmids and chromosomes at any predetermined restriction site. Nucleic Acids Res (1992) 1.18
Conferring operator specificity on restriction endonucleases. Science (1988) 1.17
Physical mapping of the att-N region of coliphage lambda: apparent oversaturation of coding capacity in the gam-ral segment. Biochimie (1974) 1.15
Organization of ribosomal protein genes in Escherichia coli. I. Physical structure of DNA from transducing lambda phages carrying genes from the aroE-str region. J Mol Biol (1976) 1.15
Conversion of the FokI endonuclease to a universal restriction enzyme: cleavage of phage M13mp7 DNA at predetermined sites. Gene (1985) 1.15
Physical mapping of Qbeta replicase binding sites on Qbeta RNA. J Mol Biol (1976) 1.15
A family of removable cassettes designed to obtain antibiotic-resistance-free genomic modifications of Escherichia coli and other bacteria. Gene (2000) 1.14
Superstructure of linear duplex DNA. Proc Natl Acad Sci U S A (1976) 1.13
Mutations and decreases in density of transforming DNA produced by derivatives of the carcinogens 2-acetyl-aminofluorene and N-methyl-4-aminoazobenzene. Mol Pharmacol (1968) 1.13
Processing of the major leftward mRNA of coliphage lambda. Virology (1976) 1.11
THE MECHANISM OF CHEMICAL MUTAGENESIS. I. KINETIC STUDIES ON THE ACTION OF TRIETHYLENE MELAMINE (TEM) AND AZASERINE. Proc Natl Acad Sci U S A (1958) 1.08
Antitermination and termination functions of the cloned nutL, N, and tL1 modules of coliphage lambda. Gene (1981) 1.05
Refined molecular weights for phage, viral and ribosomal RNA. Gene (1978) 1.03
4S oop RNA is a leader sequence for the immunity-establishment transcription in coliphage lambda. Nature (1976) 1.03
Regulation of leftward transcription in the J-b2-att region of coliphage lambda. Mol Gen Genet (1971) 1.02
Identification of the transcribing DNA strand for the rII and endolysin genes of coliphage T4. J Mol Biol (1968) 1.02
N-independent leftward transcription in coliphage lambda: deletions, insertions and new promoters bypassing termination functions. Mol Gen Genet (1979) 1.02
Congruent transcriptional controls and heterology of base sequences in coliphages lambda and phi-80. Virology (1969) 1.02
Molecular events resulting in radiation injury, repair and sensitization of DNA. Radiat Res Suppl (1967) 1.01
Structural requirements for FokI-DNA interaction and oligodeoxyribonucleotide-instructed cleavage. J Mol Biol (1996) 1.00
Size, number, and distribution of poly G binding sites on the separated DNA strands of coliphage T7. Biochim Biophys Acta (1968) 0.99
Discrete length classes of DNA depend on mode of dehydration. Proc Natl Acad Sci U S A (1978) 0.99
MECHANISM OF CHEMICAL MUTAGENESIS IV. : Reaction between Triethylene Melamine and Nucleic Acid Components. J Bacteriol (1961) 0.98
Studies on polynucleotides. XCVII. Opposing orientations and location of the su+3 gene in the transducing coliphages phi-80psu+3 and phi-80dsu+3su-3. J Mol Biol (1971) 0.96
X-ray sensitization by halopyrimidines. Cancer Chemother Rep (1974) 0.96
Nobel prizes and restriction enzymes. Gene (1978) 0.95
Transcription of the lambdadv plasmid and inhibition of lambda phages in lambdadv carrier cells of Escherichia coli. Virology (1970) 0.94
A novel method for converting common restriction enzymes into rare cutters: integration host factor-mediated Achilles' cleavage (IHF-AC). Gene (1992) 0.94
Assembly of 18-nucleotide primers by ligation of three hexamers: sequencing of large genomes by primer walking. Anal Biochem (1994) 0.91
Amplification of cloned DNA as tandem multimers using BspMI-generated asymmetric cohesive ends. Gene (1988) 0.91
Insertion sequence IS2 near the gene for prophage lambda excision. Mol Gen Genet (1976) 0.90
Analysis of the in vitro synthesis of 5'-gamma-32P-labeled transcripts from coliphage lambda by gel electrophoresis, RNA-DNA hybridization, and RNase T1 digestion. J Biol Chem (1980) 0.90
A broad-host-range in vivo pop-out and amplification system for generating large quantities of 50- to 100-kb genomic fragments for direct DNA sequencing. Gene (1996) 0.90
A novel multistep method for generating precise unidirectional deletions using BspMI, a class-IIS restriction enzyme. Gene (1986) 0.89
Asymmetric effects of deletions and substitutions on high negative interference in coliphage lambda. Genetics (1982) 0.89
In vitro transcription from the b2 region of bacteriophage lambda. Virology (1980) 0.88
Transcription termination sites in the major leftward operon of coliphage lambda. Virology (1978) 0.88
Electron microscopic mapping of RNA polymerase binding to coliphage lambda DNA. J Mol Biol (1978) 0.88
Expression of lambda int gene function in ColE1 hybrid plasmids carrying the C fragment of bacteriophage lambda. Virology (1979) 0.88
Conferring new specificities on restriction enzymes: cleavage at any predetermined site by combining adapter oligodeoxynucleotide and class-IIS enzyme. Methods Enzymol (1992) 0.87