Published in J Mol Biol on June 25, 1979
Construction of two Escherichia coli amber suppressor genes: tRNAPheCUA and tRNACysCUA. Proc Natl Acad Sci U S A (1986) 3.00
A rapid enzymatic DNA sequencing technique: determination of sequence alterations in early simian virus 40 temperature sensitive and deletion mutants. Nucleic Acids Res (1980) 2.65
Mutational studies with the trp repressor of Escherichia coli support the helix-turn-helix model of repressor recognition of operator DNA. Proc Natl Acad Sci U S A (1985) 2.48
A chimeric mammalian transactivator based on the lac repressor that is regulated by temperature and isopropyl beta-D-thiogalactopyranoside. Proc Natl Acad Sci U S A (1991) 2.35
Structure of the DNA-binding region of lac repressor inferred from its homology with cro repressor. Proc Natl Acad Sci U S A (1982) 2.09
Antisuppressor mutation in Escherichia coli defective in biosynthesis of 5-methylaminomethyl-2-thiouridine. J Bacteriol (1985) 1.82
The sup-7(st5) X gene of Caenorhabditis elegans encodes a tRNATrpUAG amber suppressor. Proc Natl Acad Sci U S A (1984) 1.80
Identification of the glpT-encoded sn-glycerol-3-phosphate permease of Escherichia coli, an oligomeric integral membrane protein. J Bacteriol (1982) 1.75
Effects of amino acid substitutions at the active site in Escherichia coli beta-galactosidase. Genetics (1988) 1.64
Evidence for a contact between glutamine-18 of lac repressor and base pair 7 of lac operator. Proc Natl Acad Sci U S A (1986) 1.59
Defined set of cloned termination suppressors: in vivo activity of isogenetic UAG, UAA, and UGA suppressor tRNAs. J Bacteriol (1984) 1.59
Dollo's law and the death and resurrection of genes. Proc Natl Acad Sci U S A (1994) 1.51
Nucleotide sequence of Klebsiella pneumoniae lac genes. J Bacteriol (1985) 1.38
Systematic alterations in the anticodon arm make tRNA(Glu)-Suoc a more efficient suppressor. EMBO J (1987) 1.28
In vivo aminoacylation of human and Xenopus suppressor tRNAs constructed by site-specific mutagenesis. Proc Natl Acad Sci U S A (1987) 1.22
Escherichia coli thymidylate synthase: amino acid substitutions by suppression of amber nonsense mutations. Proc Natl Acad Sci U S A (1990) 1.08
lac repressor-lac operator interaction: NMR observations. Proc Natl Acad Sci U S A (1982) 1.04
Induction of transversion mutations in Escherichia coli by N-methyl-N'-nitro-N-nitrosoguanidine is SOS dependent. J Bacteriol (1985) 0.98
Secondary structure of the lac repressor DNA-binding domain by two-dimensional 1H nuclear magnetic resonance in solution. Proc Natl Acad Sci U S A (1983) 0.95
Insertion mutagenesis of the lac repressor and its implications for structure-function analysis. J Bacteriol (1997) 0.95
Genetic assignment of resonances in the NMR spectrum of a protein: lac repressor. Proc Natl Acad Sci U S A (1981) 0.92
lac repressor: crystallization of intact tetramer and its complexes with inducer and operator DNA. Proc Natl Acad Sci U S A (1990) 0.89
Identification of sites influencing the folding and subunit assembly of the P22 tailspike polypeptide chain using nonsense mutations. Genetics (1987) 0.89
Exploring sequence constraints on an interhelical turn using in vivo selection for catalytic activity. Protein Sci (1998) 0.88
Intragenic suppressors of folding defects in the P22 tailspike protein. Genetics (1991) 0.87
Informational suppression as a tool for the investigation of gene structure and function. Biochem J (1982) 0.86
Drosophila nonsense suppressors: functional analysis in Saccharomyces cerevisiae, Drosophila tissue culture cells and Drosophila melanogaster. Genetics (1990) 0.84
Interaction between the lac operator and the lac repressor headpiece: fluorescence and circular dichroism studies. EMBO J (1982) 0.79
Analysis of temperature-sensitive mutations in the simian virus 40 gene encoding virion protein 1. Proc Natl Acad Sci U S A (1988) 0.77
lac Thiogalactoside transacetylase of Escherichia coli K-12 and ML. J Bacteriol (1980) 0.75
Lac repressor: a genetic and nuclear magnetic resonance study of structure and function. Biophys J (1980) 0.75
Data on publications, structural analyses, and queries used to build and utilize the AlloRep database. Data Brief (2016) 0.75
DNAse footprinting: a simple method for the detection of protein-DNA binding specificity. Nucleic Acids Res (1978) 30.43
Molecular basis of base substitution hotspots in Escherichia coli. Nature (1978) 13.79
Plasmids related to the broad host range vector, pRK290, useful for gene cloning and for monitoring gene expression. Plasmid (1985) 11.74
Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system. Mol Cell Biol (1987) 11.36
Transposable elements. Cell (1980) 10.84
On the formation of spontaneous deletions: the importance of short sequence homologies in the generation of large deletions. Cell (1982) 9.72
Crystal structure of the lactose operon repressor and its complexes with DNA and inducer. Science (1996) 9.34
A system to study promoter and terminator signals recognized by Escherichia coli RNA polymerase. Gene Amplif Anal (1981) 8.21
Genetic studies of the lac repressor. VII. On the molecular nature of spontaneous hotspots in the lacI gene of Escherichia coli. J Mol Biol (1978) 8.13
Rapid genome change in synthetic polyploids of Brassica and its implications for polyploid evolution. Proc Natl Acad Sci U S A (1995) 7.48
Genetic studies of the lac repressor. IV. Mutagenic specificity in the lacI gene of Escherichia coli. J Mol Biol (1977) 7.41
Genetic Control of Flower Development by Homeotic Genes in Antirrhinum majus. Science (1990) 7.30
Public-health impact of outdoor and traffic-related air pollution: a European assessment. Lancet (2000) 6.95
Mutagenic deamination of cytosine residues in DNA. Nature (1980) 6.26
The interaction of RNA polymerase and lac repressor with the lac control region. Nucleic Acids Res (1979) 6.17
A set of lacZ mutations in Escherichia coli that allow rapid detection of each of the six base substitutions. Proc Natl Acad Sci U S A (1989) 5.78
Lac repressor genetic map in real space. Trends Biochem Sci (1997) 5.56
The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine). J Bacteriol (1992) 5.16
Genetic studies of the lac repressor. III. Additional correlation of mutational sites with specific amino acid residues. J Mol Biol (1977) 5.15
Genetic studies of the lac repressor. I. Correlation of mutational sites with specific amino acid residues: construction of a colinear gene-protein map. J Mol Biol (1977) 5.14
New controlling element in the Lac operon of E. coli. Nature (1968) 4.63
Complementary floral homeotic phenotypes result from opposite orientations of a transposon at the plena locus of Antirrhinum. Cell (1993) 4.47
The mutY gene: a mutator locus in Escherichia coli that generates G.C----T.A transversions. Proc Natl Acad Sci U S A (1988) 4.36
Catabolite sensitive site of the lac operon. Nature (1969) 4.29
Evidence that MutY and MutM combine to prevent mutations by an oxidatively damaged form of guanine in DNA. Proc Natl Acad Sci U S A (1992) 4.29
DNA sequence at the integration sites of the insertion element IS1. Cell (1978) 4.27
Effect of butyrate enemas on the colonic mucosa in distal ulcerative colitis. Gastroenterology (1992) 4.19
European Cooperative Crohn's Disease Study (ECCDS): results of drug treatment. Gastroenterology (1984) 4.09
Effects of surrounding sequence on the suppression of nonsense codons. J Mol Biol (1983) 3.95
Molecular cloning and expression of brain-derived neurotrophic factor. Nature (1989) 3.90
The promoter-operator region of the lac operon of Escherichia coli. J Mol Biol (1968) 3.84
How lac repressor binds to DNA. Nature (1972) 3.72
The prevention of hepatitis B with vaccine. Report of the centers for disease control multi-center efficacy trial among homosexual men. Ann Intern Med (1982) 3.69
GLOBOSA: a homeotic gene which interacts with DEFICIENS in the control of Antirrhinum floral organogenesis. EMBO J (1992) 3.61
Bracteomania, an inflorescence anomaly, is caused by the loss of function of the MADS-box gene squamosa in Antirrhinum majus. EMBO J (1992) 3.60
Predicting subcellular localization of proteins using machine-learned classifiers. Bioinformatics (2004) 3.56
Proliferation of mutators in A cell population. J Bacteriol (1997) 3.55
Genetic engineering of parthenocarpic plants. Nat Biotechnol (1997) 3.31
Do not use epinephrine in digital blocks: myth or truth? Plast Reconstr Surg (2001) 3.17
Real time detection of DNA.RNA hybridization in living cells. Proc Natl Acad Sci U S A (1998) 3.10
A mechanism for repressor action. J Mol Biol (1969) 3.09
The 17-kb Tam1 element of Antirrhinum majus induces a 3-bp duplication upon integration into the chalcone synthase gene. EMBO J (1984) 3.07
Construction of two Escherichia coli amber suppressor genes: tRNAPheCUA and tRNACysCUA. Proc Natl Acad Sci U S A (1986) 3.00
Mutagenic specificity of ultraviolet light. J Mol Biol (1985) 2.89
Nucleotide sequence of the transposable DNA-element IS2. Nucleic Acids Res (1979) 2.89
Detection and isolation of the repressor protein for the tryptophan operon of Escherichia coli. Proc Natl Acad Sci U S A (1972) 2.89
Ternary complex formation between the MADS-box proteins SQUAMOSA, DEFICIENS and GLOBOSA is involved in the control of floral architecture in Antirrhinum majus. EMBO J (1999) 2.88
Escherichia coli mutY gene encodes an adenine glycosylase active on G-A mispairs. Proc Natl Acad Sci U S A (1989) 2.87
Sequence analysis of Tn9 insertions in the lacZ gene. J Mol Biol (1980) 2.85
Normal brain maturation during childhood: developmental trends characterized with diffusion-tensor MR imaging. Radiology (2001) 2.78
BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra. Nature (1991) 2.70
MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily. Nat Struct Biol (1998) 2.70
Characterization of amber and ochre suppressors in Salmonella typhimurium. J Bacteriol (1979) 2.68
A set of lacZ mutations in Escherichia coli that allow rapid detection of specific frameshift mutations. Genetics (1990) 2.66
A repair system for 8-oxo-7,8-dihydrodeoxyguanine. Biochemistry (1992) 2.65
High-density lipoprotein binding to scavenger receptor-BI activates endothelial nitric oxide synthase. Nat Med (2001) 2.61
Cyclic AMP receptor proteins interacts with lactose operator DNA. Nucleic Acids Res (1981) 2.58
mutM, a second mutator locus in Escherichia coli that generates G.C----T.A transversions. J Bacteriol (1988) 2.57
Base substitution mutations induced by metabolically activated aflatoxin B1. Proc Natl Acad Sci U S A (1983) 2.48
Molecular analysis of instability in flower pigmentation of Antirrhinum majus, following isolation of the pallida locus by transposon tagging. EMBO J (1985) 2.48
Structure and function of human perforin. Nature (1988) 2.47
Mutational specificity in bacteria. Annu Rev Genet (1983) 2.47
The consequences of growth of a mutator strain of Escherichia coli as measured by loss of function among multiple gene targets and loss of fitness. Genetics (2000) 2.47
Gene amplification in the lac region of E. coli. Cell (1984) 2.46
Translational restarts: AUG reinitiation of a lac repressor fragment. Proc Natl Acad Sci U S A (1972) 2.45
Comparison of enteral nutrition and drug treatment in active Crohn's disease. Results of the European Cooperative Crohn's Disease Study. IV. Gastroenterology (1991) 2.42
Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate. Biochemistry (1974) 2.42
Genetic studies of the lac repressor. II. Fine structure deletion map of the lacI gene, and its correlation with the physical map. J Mol Biol (1977) 2.31
Carcinogenic epoxides of benzo[a]pyrene and cyclopenta[cd]pyrene induce base substitutions via specific transversions. Proc Natl Acad Sci U S A (1982) 2.29
Escherichia coli mutY gene product is required for specific A-G----C.G mismatch correction. Proc Natl Acad Sci U S A (1988) 2.29
Specificity of mutations induced in transfected DNA by mammalian cells. EMBO J (1984) 2.27
Patient's and doctor's delay in primary breast cancer. Prognostic implications. Acta Oncol (1994) 2.27
Cloning and sequencing a human homolog (hMYH) of the Escherichia coli mutY gene whose function is required for the repair of oxidative DNA damage. J Bacteriol (1996) 2.26
MutM, a protein that prevents G.C----T.A transversions, is formamidopyrimidine-DNA glycosylase. Nucleic Acids Res (1991) 2.26
Translational reinitiation: reinitiation of lac repressor fragments at three internal sites early in the lac i gene of Escherichia coli. Proc Natl Acad Sci U S A (1974) 2.25
Specificity of mutagenesis resulting from the induction of the SOS system in the absence of mutagenic treatment. Cell (1984) 2.24
A prospective, longitudinal diffusion tensor imaging study of brain injury in newborns. Neurology (2002) 2.23
Promoter for the establishment of repressor synthesis in bacteriophage lambda. Proc Natl Acad Sci U S A (1980) 2.23
Increased risk of hepatocellular carcinoma in male hepatitis B surface antigen carriers with chronic hepatitis who have detectable urinary aflatoxin metabolite M1. Hepatology (1999) 2.16
Removal of a terminator structure by RNA processing regulates int gene expression. J Mol Biol (1984) 2.13
Carcinogens induce targeted mutations in Escherichia coli. Cell (1982) 2.12
In vivo degradation of mutant lac repressor. Nature (1970) 2.08
Appendiceal mucoceles and pseudomyxoma peritonei. Surg Gynecol Obstet (1992) 2.02
Construction of Escherichia coli amber suppressor tRNA genes. II. Synthesis of additional tRNA genes and improvement of suppressor efficiency. J Mol Biol (1990) 2.02
Genetic studies of the lac repressor. XIII. Extensive amino acid replacements generated by the use of natural and synthetic nonsense suppressors. J Mol Biol (1990) 2.01
MutY, an adenine glycosylase active on G-A mispairs, has homology to endonuclease III. Nucleic Acids Res (1990) 2.01
Lack of effect of adjuvant chemotherapy on the elimination of single dormant tumor cells in bone marrow of high-risk breast cancer patients. J Clin Oncol (2000) 1.99
Multiple interactions amongst floral homeotic MADS box proteins. EMBO J (1996) 1.96