Published in J Clin Invest on December 01, 1985
Interpretation of biomarkers of bone metabolism in children: impact of growth velocity and body size in healthy children and chronic disease. J Pediatr (2008) 1.83
Bone turnover during high dose inhaled corticosteroid treatment. Thorax (1991) 1.59
Biochemical markers of bone turnover: potential use in the investigation and management of postmenopausal osteoporosis. Osteoporos Int (2008) 1.50
Bone and collagen turnover during treatment with inhaled dry powder budesonide and beclomethasone dipropionate. Arch Dis Child (1995) 1.10
New developments in biochemical markers for osteoporosis. Calcif Tissue Int (1996) 1.08
Effects of COLIA1 polymorphisms and haplotypes on perimenopausal bone mass, postmenopausal bone loss and fracture risk. Osteoporos Int (2010) 0.84
Effects of active vitamin D3 and parathyroid hormone on the serum osteocalcin in idiopathic hypoparathyroidism and pseudohypoparathyroidism. J Clin Invest (1988) 0.81
Bone turnover during short course prednisolone treatment in patients with chronic obstructive airways disease. Thorax (1992) 0.79
1,25-Dihydroxyvitamin D stimulation test for osteoblast function in normal and osteoporotic postmenopausal women. J Clin Invest (1987) 0.78
Does low-dose and short-term glucocorticoids treatment increase the risk of osteoporosis in rheumatoid arthritis female patients? Clin Rheumatol (2007) 0.78
Direct identification of the calcium-binding amino acid, gamma-carboxyglutamate, in mineralized tissue. Proc Natl Acad Sci U S A (1975) 3.46
Characterization of a gamma-carboxyglutamic acid-containing protein from bone. Proc Natl Acad Sci U S A (1976) 3.15
Serum bone Gla-protein: a specific marker for bone formation in postmenopausal osteoporosis. Lancet (1984) 2.85
Tetracycline-based histological analysis of bone remodeling. Calcif Tissue Res (1969) 2.60
New biochemical marker for bone metabolism. Measurement by radioimmunoassay of bone GLA protein in the plasma of normal subjects and patients with bone disease. J Clin Invest (1980) 2.48
Origin of the vitamin K-dependent bone protein found in plasma and its clearance by kidney and bone. J Biol Chem (1981) 1.99
Radioimmunoassay for the vitamin K-dependent protein of bone and its discovery in plasma. Proc Natl Acad Sci U S A (1980) 1.73
Increase in serum bone gamma-carboxyglutamic acid protein with aging in women. Implications for the mechanism of age-related bone loss. J Clin Invest (1983) 1.69
Primary structure of the gamma-carboxyglutamic acid-containing protein from bovine bone. Proc Natl Acad Sci U S A (1976) 1.58
Secretion of the vitamin K-dependent protein of bone by rat osteosarcoma cells. Evidence for an intracellular precursor. J Biol Chem (1980) 1.37
Isolation and sequence of the vitamin K-dependent protein from human bone. Undercarboxylation of the first glutamic acid residue. J Biol Chem (1980) 1.19
CORRELATION OF URINARY HYDROXYPROLINE, SERUM ALKALINE PHOSPHATASE AND SKELETAL CALCIUM TURNOVER. Metabolism (1964) 1.12
Effect of renal function on plasma levels of bone Gla-protein. J Clin Endocrinol Metab (1983) 1.11
A new method for calculating the accretion rate of bone calcium and some observations on the suitability of strontium-85 as a tracer for bone calcium. Calcif Tissue Res (1976) 1.01
Bone turnover model based on a continuously expanding exchangeable calcium pool. Nature (1969) 1.01
Morphometric and dynamic studies of bone changes in hypothyroidism. Acta Pathol Microbiol Scand A (1978) 0.94
Calcium metabolism evaluated by 47Ca kinetics: estimation of dermal calcium loss. Clin Sci (Lond) (1983) 0.83
Calcium metabolism evaluated by 47calcium-kinetics: a physiological model with correction for faecal lag time and estimation of dermal calcium loss. Clin Physiol (1983) 0.81
Clinical applications of urinary hydroxyproline determination. Acta Med Scand Suppl (1975) 0.81
Alcaligenes eutrophus CH34 is a facultative chemolithotroph with plasmid-bound resistance to heavy metals. J Bacteriol (1985) 5.26
Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha. Arthritis Rheum (1993) 5.05
Characterization of a gamma-carboxyglutamic acid-containing protein from bone. Proc Natl Acad Sci U S A (1976) 3.15
Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis. Biogerontology (2001) 3.00
Cancellous bone remodeling occurs in specialized compartments lined by cells expressing osteoblastic markers. J Bone Miner Res (2001) 2.89
Diagnosis of asymptomatic primary hyperparathyroidism: proceedings of the third international workshop. J Clin Endocrinol Metab (2009) 2.69
Increased mortality in patients with a hip fracture-effect of pre-morbid conditions and post-fracture complications. Osteoporos Int (2007) 2.46
Repeated therapy with monoclonal antibody to tumour necrosis factor alpha (cA2) in patients with rheumatoid arthritis. Lancet (1994) 2.41
Proton pump inhibitors, histamine H2 receptor antagonists, and other antacid medications and the risk of fracture. Calcif Tissue Int (2006) 2.33
A method for decarboxylation of gamma-carboxyglutamic acid in proteins. Properties of the decarboxylated gamma-carboxyglutamic acid protein from calf bone. J Biol Chem (1979) 2.30
Plasma concentrations of 25-hydroxy-vitamin D and 1,25-dihydroxy-vitamin D are related to the phenotype of Gc (vitamin D-binding protein): a cross-sectional study on 595 early postmenopausal women. Calcif Tissue Int (2005) 2.23
Identification of an essential glutamic acid residue in the beta subunit of the adenosine triphosphatase from the thermophilic bacterium PS3. J Biol Chem (1981) 2.19
Fracture rates and risk factors for fractures in patients with spinal cord injury. Spinal Cord (1998) 2.07
The natural history of spinocerebellar ataxia type 1, 2, 3, and 6: a 2-year follow-up study. Neurology (2011) 2.06
Bioavailability of calcium supplements and the effect of Vitamin D: comparisons between milk, calcium carbonate, and calcium carbonate plus vitamin D. Am J Clin Nutr (1996) 2.04
Hypovitaminosis D myopathy without biochemical signs of osteomalacic bone involvement. Calcif Tissue Int (2000) 2.02
Ataxia with oculomotor apraxia type 2: clinical, biological and genotype/phenotype correlation study of a cohort of 90 patients. Brain (2009) 1.91
Commonly recommended daily intake of vitamin D is not sufficient if sunlight exposure is limited. J Intern Med (2000) 1.87
Left ventricular systolic and diastolic function in aortic stenosis. Prognostic value after valve replacement and underlying mechanisms. Eur Heart J (1997) 1.82
Effects of parathyroid hormone alone or in combination with antiresorptive therapy on bone mineral density and fracture risk--a meta-analysis. Osteoporos Int (2006) 1.79
Relative fracture risk in patients with diabetes mellitus, and the impact of insulin and oral antidiabetic medication on relative fracture risk. Diabetologia (2005) 1.79
Global vitamin D levels in relation to age, gender, skin pigmentation and latitude: an ecologic meta-regression analysis. Osteoporos Int (2008) 1.78
Serum levels of IL-6 and TNF-alpha correlate with clinicopathological features and patient survival in patients with prostate cancer. Br J Cancer (2004) 1.73
Fracture risk associated with the use of morphine and opiates. J Intern Med (2006) 1.71
Primary Sjögren's syndrome in north east England--a longitudinal study. Br J Rheumatol (1991) 1.64
Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5). J Biol Chem (1994) 1.62
Single high doses of cyclophosphamide enable the collection of high numbers of hemopoietic stem cells from the peripheral blood. Exp Hematol (1990) 1.61
The effect of iron chelation on haemopoiesis in MDS patients with transfusional iron overload. Br J Haematol (1996) 1.60
Primary structure of the gamma-carboxyglutamic acid-containing protein from bovine bone. Proc Natl Acad Sci U S A (1976) 1.58
Serum markers of type I collagen formation and degradation in metabolic bone disease: correlation with bone histomorphometry. J Bone Miner Res (1993) 1.57
Effect of vitamin D treatment in hypoparathyroid patients: a study on calcium, phosphate and magnesium homeostasis. Eur J Endocrinol (1997) 1.55
Spinocerebellar ataxia types 1, 2, 3, and 6: disease severity and nonataxia symptoms. Neurology (2008) 1.53
On-site to on-line: barriers to the use of computers for continuing education. J Contin Educ Health Prof (2000) 1.50
Myopathy in bone loss of ageing: improvement by treatment with 1 alpha-hydroxycholecalciferol and calcium. Clin Sci (Lond) (1979) 1.49
Effects of a synthetic peptide of a parathyroid hormone-related protein on calcium homeostasis, renal tubular calcium reabsorption, and bone metabolism in vivo and in vitro in rodents. J Clin Invest (1988) 1.48
Stereological considerations concerning the measurement of individual osteoid seams and resorption cavities. Bone Miner (1994) 1.47
Effects of thyroid hormones on bone and mineral metabolism. Endocrinol Metab Clin North Am (1990) 1.47
Cohort study of risk of fracture before and after surgery for primary hyperparathyroidism. BMJ (2000) 1.47
Statins decrease bone turnover in postmenopausal women: a cross-sectional study. Eur J Clin Invest (2002) 1.46
Autosomal dominant osteopetrosis. Clin Orthop Relat Res (1993) 1.44
Production of osteocalcin by human bone cells in vitro. Effects of 1,25(OH)2D3, 24,25(OH)2D3, parathyroid hormone, and glucocorticoids. Metab Bone Dis Relat Res (1984) 1.42
Familial isolated primary hyperparathyroidism. Clin Endocrinol (Oxf) (1994) 1.42
Stroke in relation to use of raloxifene and other drugs against osteoporosis. Osteoporos Int (2010) 1.42
Polymorphisms of muscle genes are associated with bone mass and incident osteoporotic fractures in Caucasians. Calcif Tissue Int (2013) 1.40
Efficacy of wheat germ lectin-precipitated alkaline phosphatase in serum as an estimator of bone mineralization rate: comparison to serum total alkaline phosphatase and serum bone Gla-protein. Calcif Tissue Int (1989) 1.39
[Costs of different intervention strategies to prevent hip fractures]. Ugeskr Laeger (1999) 1.39
Anxiolytics, sedatives, antidepressants, neuroleptics and the risk of fracture. Osteoporos Int (2006) 1.39
Bone histomorphometry in hypoparathyroid patients treated with vitamin D. Bone (1996) 1.37
Fracture risk is increased in Crohn's disease, but not in ulcerative colitis. Gut (2000) 1.33
Vitamin D status, seasonal variations, parathyroid adenoma weight and bone mineral density in primary hyperparathyroidism. Clin Endocrinol (Oxf) (2005) 1.30
Vitamin D and its binding protein Gc: long-term variability in peri- and postmenopausal women with and without hormone replacement therapy. Scand J Clin Lab Invest (2006) 1.29
The effect of single oral doses of prednisone on the circadian rhythm of serum osteocalcin in normal subjects. J Clin Endocrinol Metab (1988) 1.29
Fracture risk in patients treated for hyperthyroidism. Thyroid (2000) 1.25
Sex differences in age-related changes in vertebral body size, density and biomechanical competence in normal individuals. Bone (1990) 1.23
Risedronate increases bone mass in an early postmenopausal population: two years of treatment plus one year of follow-up. J Clin Endocrinol Metab (1998) 1.22
Lumbar vertebral body compressive strength evaluated by dual-energy X-ray absorptiometry, quantitative computed tomography, and ashing. Bone (1999) 1.22
Silent pulmonary embolism in patients with deep venous thrombosis. Incidence and fate in a randomized, controlled trial of anticoagulation versus no anticoagulation. J Intern Med (1994) 1.20
The consensus workshops for the detection of autoantibodies to intracellular antigens in rheumatic diseases. J Immunol Methods (1991) 1.19
Isolation and sequence of the vitamin K-dependent protein from human bone. Undercarboxylation of the first glutamic acid residue. J Biol Chem (1980) 1.19
Age- and sex-related changes in iliac cortical bone mass and remodeling. Bone (1994) 1.19
Fractures in patients with primary idiopathic hypothyroidism. Thyroid (2000) 1.17
Biomechanical competence of vertebral trabecular bone in relation to ash density and age in normal individuals. Bone (1987) 1.17
Autoregulation and CO2 responses of cerebral blood flow in patients with acute severe head injury. J Neurosurg (1978) 1.17
Suppression of fever and the acute-phase response in a patient with juvenile chronic arthritis treated with monoclonal antibody to tumour necrosis factor-alpha (cA2). Br J Rheumatol (1997) 1.16
Normal vertebral body size and compressive strength: relations to age and to vertebral and iliac trabecular bone compressive strength. Bone (1986) 1.16
Histomorphometric analysis of normal bone from the iliac crest. Acta Pathol Microbiol Scand A (1978) 1.16
Vitamin D insufficiency in Greenlanders on a westernized fare: ethnic differences in calcitropic hormones between Greenlanders and Danes. Calcif Tissue Int (2003) 1.14
Reconstruction of the formative site in iliac trabecular bone in 20 normal individuals employing a kinetic model for matrix and mineral apposition. Metab Bone Dis Relat Res (1984) 1.14
Fracture risk is increased in epilepsy. Acta Neurol Scand (1999) 1.13
Anti-tumour necrosis factor specific antibody (infliximab) treatment provides insights into the pathophysiology of rheumatoid arthritis. Ann Rheum Dis (1999) 1.12
Tetracycline double-labeling of iliac trabecular bone in 41 normal adults. Calcif Tissue Res (1978) 1.12
Age-related changes in the biochemical properties of human cancellous bone collagen: relationship to bone strength. Calcif Tissue Int (1999) 1.12
Reduced concentration of collagen reducible cross links in human trabecular bone with respect to age and osteoporosis. Bone (1996) 1.11
Autoantibodies in malaria, tuberculosis and hepatitis B in a west African population. Clin Exp Immunol (1993) 1.10
Missing observations in bone histomorphometry on osteoporosis: implications and suggestions for an approach. Bone (1999) 1.10
Trabecular bone remodeling and balance in primary hyperparathyroidism. Bone (1986) 1.10
Dynamic changes in regional CBF, intraventricular pressure, CSF pH and lactate levels during the acute phase of head injury. J Neurosurg (1976) 1.09
Effects of 25OHD concentrations on chances of pregnancy and pregnancy outcomes: a cohort study in healthy Danish women. Eur J Clin Nutr (2012) 1.09
Effects of paracetamol, non-steroidal anti-inflammatory drugs, acetylsalicylic acid, and opioids on bone mineral density and risk of fracture: results of the Danish Osteoporosis Prevention Study (DOPS). Osteoporos Int (2011) 1.08
Multiplex immune serum biomarker profiling in sarcoidosis and systemic sclerosis. Eur Respir J (2009) 1.08
Assessment of bone remodeling using biochemical indicators of type I collagen synthesis and degradation: relation to calcium kinetics. Bone Miner (1994) 1.07
A randomized study on the effects of estrogen/gestagen or high dose oral calcium on trabecular bone remodeling in postmenopausal osteoporosis. Bone (1989) 1.06
Fracture risk associated with use of nonsteroidal anti-inflammatory drugs, acetylsalicylic acid, and acetaminophen and the effects of rheumatoid arthritis and osteoarthritis. Calcif Tissue Int (2006) 1.06
Anticoagulant therapy in deep venous thrombosis. A randomized controlled study. Thromb Res (1994) 1.06
Reduced relative risk of fractures among users of lithium. Calcif Tissue Int (2005) 1.05
Identification of Mycobacterium shimoidei in a tuberculosis-like cavity by 16S ribosomal DNA direct sequencing. Eur J Clin Microbiol Infect Dis (1996) 1.04
Positive effects of physiotherapy on chronic pain and performance in osteoporosis. Osteoporos Int (1998) 1.04
Myocardial structure as a determinant of pre- and postoperative ventricular function and long-term prognosis after valve replacement for aortic stenosis. Eur Heart J (1998) 1.03
An evaluation of the quantitative parameters applied in bone histology. Acta Pathol Microbiol Scand A (1978) 1.02
Biological insights from clinical trials with anti-TNF therapy. Springer Semin Immunopathol (1998) 1.02
Hormone replacement therapy dissociates fat mass and bone mass, and tends to reduce weight gain in early postmenopausal women: a randomized controlled 5-year clinical trial of the Danish Osteoporosis Prevention Study. J Bone Miner Res (2003) 1.02