Published in Antimicrob Agents Chemother on January 01, 1985
Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast. Antimicrob Agents Chemother (2007) 2.12
Tetracyclines specifically target the apicoplast of the malaria parasite Plasmodium falciparum. Antimicrob Agents Chemother (2006) 1.95
Activity of clindamycin with primaquine against Pneumocystis carinii in vitro and in vivo. Antimicrob Agents Chemother (1988) 1.64
Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase. Proc Natl Acad Sci U S A (2009) 1.63
Inhibition of cytoplasmic and organellar protein synthesis in Toxoplasma gondii. Implications for the target of macrolide antibiotics. J Clin Invest (1995) 1.45
In vitro activities of antibiotics against Plasmodium falciparum are inhibited by iron. Antimicrob Agents Chemother (2001) 1.45
Reliability of antimalarial sensitivity tests depends on drug mechanisms of action. J Clin Microbiol (2010) 1.43
Multinormal in vitro distribution model suitable for the distribution of Plasmodium falciparum chemosusceptibility to doxycycline. Antimicrob Agents Chemother (2008) 1.29
Antimalarial dyes revisited: xanthenes, azines, oxazines, and thiazines. Antimicrob Agents Chemother (1995) 1.28
Antimalarial agents: mechanisms of action. Antimicrob Agents Chemother (1988) 1.18
Homologies between the contiguous and fragmented rRNAs of the two Plasmodium falciparum extrachromosomal DNAs are limited to core sequences. Nucleic Acids Res (1992) 1.18
Activity of fluoroquinolone antibiotics against Plasmodium falciparum in vitro. Antimicrob Agents Chemother (1988) 1.15
Differential in vitro activities of ionophore compounds against Plasmodium falciparum and mammalian cells. Antimicrob Agents Chemother (1996) 1.07
Pharmacokinetics of oral doxycycline during combination treatment of severe falciparum malaria. Antimicrob Agents Chemother (2005) 1.07
In vitro activity of mirincamycin (U24729A) against Plasmodium falciparum isolates from Gabon. Antimicrob Agents Chemother (2009) 1.06
The antibiotic micrococcin is a potent inhibitor of growth and protein synthesis in the malaria parasite. Antimicrob Agents Chemother (1998) 1.05
Influence of oxygen on asexual blood cycle and susceptibility of Plasmodium falciparum to chloroquine: requirement of a standardized in vitro assay. Malar J (2007) 1.02
Use of the atmospheric generators for capnophilic bacteria Genbag-CO2 for the evaluation of in vitro Plasmodium falciparum susceptibility to standard anti-malarial drugs. Malar J (2011) 0.98
Multinormal in vitro distribution of Plasmodium falciparum susceptibility to piperaquine and pyronaridine. Malar J (2015) 0.95
Model system to define pharmacokinetic requirements for antimalarial drug efficacy. Sci Transl Med (2013) 0.94
A SYBR Green 1-based in vitro test of susceptibility of Ghanaian Plasmodium falciparum clinical isolates to a panel of anti-malarial drugs. Malar J (2013) 0.91
Telithromycin and quinupristin-dalfopristin induce delayed death in Plasmodium falciparum. Antimicrob Agents Chemother (2007) 0.89
Potentiation of an antimalarial oxidant drug. Antimicrob Agents Chemother (1997) 0.87
Effect of calmodulin inhibitors on viability and mitochondrial potential of Plasmodium falciparum in culture. Antimicrob Agents Chemother (1986) 0.86
Tetracyclines as antiparasitic agents: lipophilic derivatives are highly active against Giardia lamblia in vitro. Antimicrob Agents Chemother (1989) 0.83
Potentiation of chloroquine activity against Plasmodium falciparum by the peroxidase-hydrogen peroxide system. Antimicrob Agents Chemother (1990) 0.82
Affinity-purified antibodies to ring-infected erythrocyte surface antigen do not correlate with merozoite invasion inhibition in Plasmodium falciparum. Infect Immun (1988) 0.81
In vitro and in vivo antimalarial efficacies of optimized tetracyclines. Antimicrob Agents Chemother (2013) 0.81
Activities of pefloxacin and ciprofloxacin against experimental malaria in mice. Antimicrob Agents Chemother (1990) 0.81
Molecular Markers and In Vitro Susceptibility to Doxycycline in Plasmodium falciparum Isolates from Thailand. Antimicrob Agents Chemother (2015) 0.78
Targeting the gyrase of Plasmodium falciparum with topoisomerase poisons. Biochem Pharmacol (2015) 0.77
Modification of triclosan scaffold in search of improved inhibitors for enoyl-acyl carrier protein (ACP) reductase in Toxoplasma gondii. ChemMedChem (2013) 0.77
Tetracyclines in malaria. Malar J (2015) 0.77
An adjustable gas-mixing device to increase feasibility of in vitro culture of Plasmodium falciparum parasites in the field. PLoS One (2014) 0.76
Mode of action of tubulozoles against Plasmodium falciparum in vitro. Antimicrob Agents Chemother (1990) 0.76
Absence of correlation between ex vivo susceptibility to doxycycline and pfteQ-pfmdt gene polymorphism in French Guiana. Malar J (2015) 0.75
Metabolomic Profiling of the Malaria Box Reveals Antimalarial Target Pathways. Antimicrob Agents Chemother (2016) 0.75
Human malaria parasites in continuous culture. Science (1976) 59.70
Synchronization of Plasmodium falciparum erythrocytic stages in culture. J Parasitol (1979) 23.90
Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique. Antimicrob Agents Chemother (1979) 17.49
Localization of mitochondria in living cells with rhodamine 123. Proc Natl Acad Sci U S A (1980) 7.31
Plasmodium falciparum in culture: use of outdated erthrocytes and description of the candle jar method. J Parasitol (1977) 4.48
Biochemistry of Plasmodium (malarial parasites). Microbiol Rev (1979) 3.86
New experimental antimalarial drugs. Adv Pharmacol Chemother (1979) 2.48
Hypothesis on the molecular basis of the antifungal activity of N-substituted imidazoles and triazoles. Biochem Soc Trans (1983) 1.85
Malaria--resurgence, resistance, and research. (First of two parts). N Engl J Med (1983) 1.82
Stage-dependent effects of chloroquine on Plasmodium falciparum in vitro. J Protozool (1983) 1.70
Plasmodium falciparum in vitro: determination of chloroquine sensitivity of three new strains by a modified 48-hour test. Am J Trop Med Hyg (1980) 1.66
Plasmodium falciparum: microaerophilic requirements in human red blood cells. Exp Parasitol (1979) 1.52
Probing mitochondria in living cells with rhodamine 123. Cold Spring Harb Symp Quant Biol (1982) 1.46
A radical interpretation of immunity to malaria parasites. Lancet (1982) 1.46
The activities of chlorinated lincomycin derivatives against infections with Plasmodium cynomolgi in Macaca mulatta. Am J Trop Med Hyg (1970) 1.36
Effects of antibiotics on Plasmodium falciparum in vitro. Am J Trop Med Hyg (1983) 1.35
An in vitro assay system for the identification of potential antimalarial drugs. J Parasitol (1983) 1.20
Selective toxicity of rhodamine 123 in carcinoma cells in vitro. Cancer Res (1983) 1.19
Antimalarial effects of tetracyclines in man. J Trop Med Hyg (1971) 1.19
Minocycline and tetracycline treatment of acute falciparum malaria in Thailand. Am J Trop Med Hyg (1972) 1.17
Anticarcinoma activity in vivo of rhodamine 123, a mitochondrial-specific dye. Science (1983) 1.17
Tetraethylthiuram disulfide (Antabuse) inhibits the human malaria parasite Plasmodium falciparum. Proc Natl Acad Sci U S A (1979) 1.14
Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. J Med Chem (1984) 1.13
The effect of bacterial DNA gyrase inhibitors on DNA synthesis in mammalian mitochondria. Biochim Biophys Acta (1983) 1.09
Activity of chlorinated lincomycin analogues against Plasmodium cynomolgi in rhesus monkeys. Am J Trop Med Hyg (1969) 1.09
Antiplasmodial activity of 7-halogenated lincomycins. J Parasitol (1968) 1.08
Activity of two chlorinated lincomycin analogues against chloroquine-resistant falciparum malaria in owl monkeys. Antimicrob Agents Chemother (1972) 1.08
Pharmacokinetics of chloroquine diphosphate in the dog. J Pharmacol Exp Ther (1983) 1.00
Inhibition of rodent malaria in mice by rifampicin. Nature (1970) 0.98
The use of antibiotics in the treatment of malaria. Ann N Y Acad Sci (1952) 0.97
Clinical drug-resistant falciparum malaria acquired from cultured parasites. Am J Trop Med Hyg (1981) 0.96
Oxygen enhances the antimalarial activity of the imidazoles. Am J Trop Med Hyg (1983) 0.95
Effects of tetracycline against chloroquine-resistant and chloroquine-sensitive Plasmodium falciparum. Am J Trop Med Hyg (1971) 0.94
Effects of minocycline against chloroquine-resistant falciparum malaria. Am J Trop Med Hyg (1972) 0.94
Plasmodium falciparum: in vitro induction of resistance to aminopterin. Exp Parasitol (1981) 0.94
Antimalarial activity of selected aromatic chelators. II. Substituted quinolines and quinoline-N-oxides. Mol Pharmacol (1981) 0.91
Rhodamine 123 inhibits bioenergetic function in isolated rat liver mitochondria. Biochem Biophys Res Commun (1984) 0.91
Treatment of falciparum malaria with clindamycin. Rev Inst Med Trop Sao Paulo (1983) 0.87
Antimalarial effects of clindamycin in man. Am J Trop Med Hyg (1975) 0.85
Transport of ions in erythrocytes infected by plasmodia. Ciba Found Symp (1983) 0.85
Evaluation of clindamycin in combination with quinine against multidrug-resistant strains of Plasmodium falciparum. Am J Trop Med Hyg (1974) 0.85
Study on clindamycin in the treatment of falciparum malaria. Rev Inst Med Trop Sao Paulo (1983) 0.82
The chemotherapy of rodent malaria, XXIV. The blood schizontocidal action of erythromycin upon Plasmodium berghei. Ann Trop Med Parasitol (1976) 0.80
Chloramphenicol in malaria. Am J Trop Med Hyg (1952) 0.79
Why still prescribe chloramphenicol in 1983? Comparison of the clinical and biological hematologic effects of chloramphenicol and thiamphenicol. Blut (1983) 0.78
The action of dyes, antibiotics, and some miscellaneous compounds against Plasmodium berghei. Br J Pharmacol Chemother (1953) 0.78
Human malaria parasites in continuous culture. Science (1976) 59.70
Plasmodium falciparum in culture: use of outdated erthrocytes and description of the candle jar method. J Parasitol (1977) 4.48
Concentration from continuous culture of erythrocytes infected with trophozoites and schizonts of Plasmodium falciparum. Am J Trop Med Hyg (1978) 3.46
Plasmodium falciparum in culture: establishment of additional strains. Am J Trop Med Hyg (1978) 2.85
Fine structure of human malaria in vitro. J Protozool (1978) 2.32
Plasmodium falciparum strain-specific antibody blocks binding of infected erythrocytes to amelanotic melanoma cells. Nature (1983) 2.32
Association between human serum-induced crisis forms in cultured Plasmodium falciparum and clinical immunity to malaria in Sudan. Infect Immun (1983) 2.08
Nutritional requirements of Plasmodium falciparum in culture. I. Exogenously supplied dialyzable components necessary for continuous growth. J Protozool (1985) 1.91
Stage-dependent effects of chloroquine on Plasmodium falciparum in vitro. J Protozool (1983) 1.70
Induction of crisis forms in cultured Plasmodium falciparum with human immune serum from Sudan. Science (1982) 1.57
Uptake of [3H]chloroquine by drug-sensitive and -resistant strains of the human malaria parasite Plasmodium falciparum. Biochem Pharmacol (1986) 1.53
Stage specific actions of antimalarial drugs on Plasmodium falciparum in culture. Am J Trop Med Hyg (1989) 1.51
Why veterinarians should care more about parasitology. Parasitol Today (2000) 1.47
Transient depletion of T cells with high LFA-1 expression from peripheral circulation during acute Plasmodium falciparum malaria. Eur J Immunol (1991) 1.44
Evidence of endothelial inflammation, T cell activation, and T cell reallocation in uncomplicated Plasmodium falciparum malaria. Am J Trop Med Hyg (1994) 1.42
Agglutination of Plasmodium falciparum-infected erythrocytes from east and west African isolates by human sera from distant geographic regions. Am J Trop Med Hyg (1992) 1.41
[Episodic hypoxemia and coinciding ECG changes after acute myocardial infarction]. Ugeskr Laeger (1995) 1.37
Effects of antibiotics on Plasmodium falciparum in vitro. Am J Trop Med Hyg (1983) 1.35
Development of the mesencephalic dopaminergic neuron system is compromised in the absence of neurogenin 2. Development (2006) 1.33
Continuous culture of Plasmodium falciparum: its impact on malaria research. Int J Parasitol (1997) 1.28
Comparison of immunity to malaria in Sudan and Indonesia: crisis-form versus merozoite-invasion inhibition. Proc Natl Acad Sci U S A (1984) 1.28
Immunization against malaria with antigen from Plasmodium falciparum cultivated in vitro. Proc Natl Acad Sci U S A (1978) 1.27
The mitochondrion of Plasmodium falciparum visualized by rhodamine 123 fluorescence. J Protozool (1985) 1.27
Increased plasma levels of soluble ICAM-1 and ELAM-1 (E-selectin) during acute Plasmodium falciparum malaria. Immunol Lett (1993) 1.25
Potential antimalarial candidates from African plants: and in vitro approach using Plasmodium falciparum. J Ethnopharmacol (1986) 1.24
Mitogenic activity of extracts from continuous cultures of Plasmodium falciparum. Am J Trop Med Hyg (1982) 1.20
An in vitro assay system for the identification of potential antimalarial drugs. J Parasitol (1983) 1.20
Cultivation of erythrocytic stages. Bull World Health Organ (1977) 1.20
Plasmodium falciparum: rapid assay for in vitro inhibition due to human serum from residents of malarious areas. Exp Parasitol (1982) 1.18
Loss of cellular immune reactivity during acute Plasmodium falciparum malaria. FEMS Microbiol Immunol (1991) 1.15
Lack of cross-resistance to 4-aminoquinolines in chloroquine-resistant Plasmodium falciparum in vitro. J Parasitol (1983) 1.13
Observations on gametogenesis in Plasmodium falciparum from continuous culture. J Protozool (1979) 1.13
Ivermectin distribution in the plasma and tissues of patients infected with Onchocerca volvulus. Eur J Clin Pharmacol (1996) 1.12
Possible secretory function of the rhoptries of Eimeria magna during penetration of cultured cells. J Parasitol (1976) 1.11
Longitudinal study on the in vitro immune response to Plasmodium falciparum in Sudan. Infect Immun (1984) 1.10
Current concepts and new ideas on the mechanism of action of quinoline-containing antimalarials. Biochem Pharmacol (1987) 1.10
Soluble Plasmodium falciparum antigens contain carbohydrate moieties important for immune reactivity. J Clin Microbiol (1987) 1.09
Effects of mitochondrial inhibitors on intraerythrocytic Plasmodium falciparum in in vitro cultures. J Protozool (1986) 1.09
Comparison of inducers of crisis forms in Plasmodium falciparum in vitro. Am J Trop Med Hyg (1985) 1.08
Making the most of Papua New Guinea's biodiversity: Establishment of an integrated set of programs that link botanical survey with pharmacological assessment in "The Land of the Unexpected" Pharm Biol (2009) 1.08
Epirubicin cardiotoxicity: a study of 135 patients with advanced breast cancer. J Clin Oncol (1990) 1.06
Ultrastructure of the invasion of Eimeria magna sporozoites into cultured cells. J Protozool (1975) 1.05
High proportion of subclinical Plasmodium falciparum infections in an area of seasonal and unstable malaria in Sudan. Am J Trop Med Hyg (1995) 1.04
Synthesis and evaluation of 1,2,2-tris(sulfonyl)hydrazines as antineoplastic and trypanocidal agents. J Med Chem (1990) 1.04
Cell-mediated immune responses to Plasmodium falciparum purified soluble antigens in sickle-cell trait subjects. Immunol Lett (1990) 1.00
Appearance of nephritis associated with type 57 streptococcal impetigo in North America. N Engl J Med (1970) 0.99
Antibody responses to Rhoptry-Associated Protein-1 (RAP-1) of Plasmodium falciparum parasites in humans from areas of different malaria endemicity. Parasite Immunol (1997) 0.98
Theoretical perspectives on anthelmintic drug discovery: interplay of transport kinetics, physicochemical properties, and in vitro activity of anthelmintic drugs. J Pharm Sci (1994) 0.96
Clinical drug-resistant falciparum malaria acquired from cultured parasites. Am J Trop Med Hyg (1981) 0.96
Nutritional requirements of Plasmodium falciparum in culture. III. Further observations on essential nutrients and antimetabolites. J Protozool (1985) 0.95
Studies on serum requirements for the cultivation of Plasmodium falciparum. 1. Animal sera. Bull World Health Organ (1982) 0.94
Kinetic modelling of the response of Plasmodium falciparum to chloroquine and its experimental testing in vitro. Implications for mechanism of action of and resistance to the drug. Biochem Pharmacol (1990) 0.94
Inhibitory effects of nematode FMRFamide-related peptides (FaRPs) on muscle strips from Ascaris suum. Invert Neurosci (1995) 0.93
Activity of quinoline-containing antimalarials against chloroquine-sensitive and -resistant strains of Plasmodium falciparum in vitro. Trans R Soc Trop Med Hyg (1987) 0.92
Foreword: towards markers for anthelmintic resistance in helminths of importance in animal and human health. Parasitology (2007) 0.91
Electroshock for atrial flutter and atrial fibrillation. Follow-up studies on 50 patients. JAMA (1965) 0.90
A histidine-rich protein from Plasmodium falciparum and its interaction with membranes. Bull World Health Organ (1977) 0.90
Identification of an erythrocyte binding peptide from the erythrocyte binding antigen, EBA-175, which blocks parasite multiplication and induces peptide-blocking antibodies. Infect Immun (1998) 0.90
Effects of antiphagocytic agents on penetration of Eimeria magna sporozoites into cultured cells. J Parasitol (1976) 0.90
Tumor necrosis factor does not induce Plasmodium falciparum crisis forms. Infect Immun (1987) 0.90
Haemonchus contortus: sequence heterogeneity of internucleotide binding domains from P-glycoproteins. Exp Parasitol (1999) 0.89
Characteristics of chloroquine binding to glass and plastic. Am J Trop Med Hyg (1983) 0.89
Reactivity profile of human anti-82-kilodalton rhoptry protein antibodies generated during natural infection with Plasmodium falciparum. Infect Immun (1993) 0.89
Drug response and genetic characterization of Plasmodium falciparum clones recently isolated from a Sudanese village. Trans R Soc Trop Med Hyg (1993) 0.89
Seasonal changes in cell mediated immune responses to soluble Plasmodium falciparum antigens in children with haemoglobin AA and haemoglobin AS. Trans R Soc Trop Med Hyg (1992) 0.88
Nitric oxide mediates the inhibitory effects of SDPNFLRFamide, a nematode FMRFamide-related neuropeptide, in Ascaris suum. J Neurophysiol (1995) 0.88
A functional amino acid substitution in the glucose-dependent insulinotropic polypeptide receptor (GIPR) gene is associated with lower bone mineral density and increased fracture risk. J Clin Endocrinol Metab (2014) 0.88
Mechanistic approaches to quantitate anthelmintic absorption by gastrointestinal nematodes. Parasitol Today (1993) 0.88
Synthesis and evaluation of 1-acyl-1,2-bis(methylsulfonyl)-2-(2- chloroethyl)hydrazines as antineoplastic agents. J Med Chem (1993) 0.87
Cloning of a cDNA encoding phosphofructokinase from Haemonchus contortus. Mol Biochem Parasitol (1991) 0.87
Depression and symptoms of attention deficit disorder with hyperactivity. J Am Acad Child Adolesc Psychiatry (1988) 0.87
Modulation of the cellular immune response during Plasmodium falciparum infections in sickle cell trait individuals. Clin Exp Immunol (1992) 0.87
Uptake of antibiotics by Plasmodium falciparum in culture. Am J Trop Med Hyg (1988) 0.87
Clindamycin for the treatment of falciparum malaria in Sudan. Am J Trop Med Hyg (1985) 0.86
FMRFamide-related peptides (FaRPs) in nematodes: occurrence and neuromuscular physiology. Parasitology (1996) 0.86
Effect of calmodulin inhibitors on viability and mitochondrial potential of Plasmodium falciparum in culture. Antimicrob Agents Chemother (1986) 0.86