Published in Proc Natl Acad Sci U S A on August 01, 1985
Assembly of vaccinia virus: the second wrapping cisterna is derived from the trans Golgi network. J Virol (1994) 4.67
Structural relationships between clathrin assembly proteins from the Golgi and the plasma membrane. EMBO J (1988) 4.06
Differential extractability of influenza virus hemagglutinin during intracellular transport in polarized epithelial cells and nonpolar fibroblasts. J Cell Biol (1989) 2.75
Clathrin-coated vesicular transport of secretory proteins during the formation of ACTH-containing secretory granules in AtT20 cells. J Cell Biol (1986) 2.40
Coronavirus M proteins accumulate in the Golgi complex beyond the site of virion budding. J Virol (1994) 2.27
Mammalian Sec23p homologue is restricted to the endoplasmic reticulum transitional cytoplasm. Proc Natl Acad Sci U S A (1991) 2.27
The TGN38 glycoprotein contains two non-overlapping signals that mediate localization to the trans-Golgi network. J Cell Biol (1994) 2.11
Post-Golgi membrane traffic: brefeldin A inhibits export from distal Golgi compartments to the cell surface but not recycling. J Cell Biol (1992) 1.75
Sorting and processing of secretory proteins. Biochem J (1994) 1.65
Newly synthesized synaptophysin is transported to synaptic-like microvesicles via constitutive secretory vesicles and the plasma membrane. EMBO J (1991) 1.63
Structure of the novel membrane-coating material in proton-secreting epithelial cells and identification as an H+ATPase. J Cell Biol (1987) 1.59
The AP-1 adaptor complex binds to immature secretory granules from PC12 cells, and is regulated by ADP-ribosylation factor. J Cell Biol (1996) 1.55
Low cytoplasmic pH inhibits endocytosis and transport from the trans-Golgi network to the cell surface. J Cell Biol (1989) 1.45
Coat proteins isolated from clathrin coated vesicles can assemble into coated pits. J Cell Biol (1989) 1.35
"BFA bodies": a subcompartment of the endoplasmic reticulum. Proc Natl Acad Sci U S A (1993) 1.22
Mechanisms and concepts paving the way towards a complete transport cycle of plant vacuolar sorting receptors. Plant Cell (2012) 1.19
Differential localization of vesicular acetylcholine and monoamine transporters in PC12 cells but not CHO cells. J Cell Biol (1997) 1.04
Discovery and progress in our understanding of the regulated secretory pathway in neuroendocrine cells. Histochem Cell Biol (2008) 1.00
GGA function is required for maturation of neuroendocrine secretory granules. EMBO J (2006) 0.99
Lysosomal enzyme precursors in coated vesicles derived from the exocytic and endocytic pathways. J Cell Biol (1987) 0.98
pH-dependent processing of secretogranin II by the endopeptidase PC2 in isolated immature secretory granules. Biochem J (1997) 0.95
Multiple-labelling immunoEM using different sizes of colloidal gold: alternative approaches to test for differential distribution and colocalization in subcellular structures. Histochem Cell Biol (2011) 0.87
Role of adaptor proteins in secretory granule biogenesis and maturation. Front Endocrinol (Lausanne) (2013) 0.87
Souffle/Spastizin controls secretory vesicle maturation during zebrafish oogenesis. PLoS Genet (2014) 0.82
Redistribution of clathrin-coated vesicle adaptor complexes during adipocytic differentiation of 3T3-L1 cells. J Cell Biol (1993) 0.82
Intracellular aspects of the process of protein synthesis. Science (1975) 25.21
Coated pits, coated vesicles, and receptor-mediated endocytosis. Nature (1979) 17.18
Studies on antibody production. I. A method for the histochemical demonstration of specific antibody and its application to a study of the hyperimmune rabbit. J Exp Med (1955) 16.36
Method for the isolation of intact islets of Langerhans from the rat pancreas. Diabetes (1967) 11.63
Ultrastructural localization of intracellular antigens by the use of protein A-gold complex. J Histochem Cytochem (1978) 7.15
Antibodies to the Golgi complex and the rough endoplasmic reticulum. J Cell Biol (1982) 7.02
The Golgi apparatus (complex)-(1954-1981)-from artifact to center stage. J Cell Biol (1981) 6.54
Clathrin: a unique protein associated with intracellular transfer of membrane by coated vesicles. Proc Natl Acad Sci U S A (1976) 5.52
Membrane recycling by coated vesicles. Annu Rev Biochem (1981) 5.27
Assembly units of clathrin coats. Nature (1981) 4.70
The phosphomannosyl recognition system for intracellular and intercellular transport of lysosomal enzymes. J Cell Biochem (1982) 4.50
Sizing of protein A-colloidal gold probes for immunoelectron microscopy. J Cell Biol (1981) 4.32
Coated vesicles transport newly synthesized membrane glycoproteins from endoplasmic reticulum to plasma membrane in two successive stages. Proc Natl Acad Sci U S A (1980) 3.51
Assembly and packing of clathrin into coats. J Cell Biol (1981) 2.88
Golgi membranes contain an electrogenic H+ pump in parallel to a chloride conductance. J Cell Biol (1983) 2.86
Clathrin-coated vesicles contain an ATP-dependent proton pump. Proc Natl Acad Sci U S A (1983) 2.84
An ATP-driven proton pump in clathrin-coated vesicles. J Biol Chem (1983) 2.65
Macro- and micro-domains in the endocrine pancreas. Diabetes (1982) 2.43
Specimen preparation for electron microscopy using low temperature embedding resins. J Microsc (1982) 2.33
Transport of the membrane glycoprotein of vesicular stomatitis virus to the cell surface in two stages by clathrin-coated vesicles. J Cell Biol (1980) 2.08
Two rapid and simple methods used for the removal of resins from 1.0 micron thick epoxy sections. J Microsc (1978) 2.06
A clathrin-coated, Golgi-related compartment of the insulin secreting cell accumulates proinsulin in the presence of monensin. Cell (1984) 1.99
A monoclonal antibody to the heavy chain of clathrin. EMBO J (1983) 1.94
Conversion of proinsulin to insulin: involvement of a 31,500 molecular weight thiol protease. Proc Natl Acad Sci U S A (1982) 1.70
Nonconverted, amino acid analog-modified proinsulin stays in a Golgi-derived clathrin-coated membrane compartment. J Cell Biol (1984) 0.98
Ultrastructural studies of the hyperplastic islets of Langerhans of spiny mice (Acomys cahirinus) before and during the development of hyperglycemia. Diabetologia (1967) 0.97
(Pro)insulin associates with Golgi membranes of pancreatic B cells. Proc Natl Acad Sci U S A (1984) 0.89
COPII: a membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum. Cell (1994) 10.01
Molecular dissection of the secretory pathway. Nature (1992) 7.38
Ultrastructural localization of intracellular antigens by the use of protein A-gold complex. J Histochem Cytochem (1978) 7.15
Antibodies to the Golgi complex and the rough endoplasmic reticulum. J Cell Biol (1982) 7.02
Coat proteins and vesicle budding. Science (1996) 7.00
Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic. Cell (1991) 6.30
Lipotoxic heart disease in obese rats: implications for human obesity. Proc Natl Acad Sci U S A (2000) 5.65
Involvement of GTP-binding "G" proteins in transport through the Golgi stack. Cell (1987) 5.28
Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor. Cell (1991) 4.98
A monoclonal antibody against a 135-K Golgi membrane protein. EMBO J (1982) 4.89
ADP-ribosylation factor is a subunit of the coat of Golgi-derived COP-coated vesicles: a novel role for a GTP-binding protein. Cell (1991) 4.80
COPII-coated vesicle formation reconstituted with purified coat proteins and chemically defined liposomes. Cell (1998) 4.73
Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis. EMBO J (2001) 4.70
Purification of a novel class of coated vesicles mediating biosynthetic protein transport through the Golgi stack. Cell (1989) 4.65
Apical membrane aminopeptidase appears at site of cell-cell contact in cultured kidney epithelial cells. Proc Natl Acad Sci U S A (1980) 4.63
Passage of viral membrane proteins through the Golgi complex. J Mol Biol (1981) 4.48
SSR alpha and associated calnexin are major calcium binding proteins of the endoplasmic reticulum membrane. J Biol Chem (1991) 4.48
Role of an N-ethylmaleimide-sensitive transport component in promoting fusion of transport vesicles with cisternae of the Golgi stack. Cell (1988) 4.37
Antibody-induced linkages of plasma membrane proteins to intracellular actomyosin-containing filaments in cultured fibroblasts. Proc Natl Acad Sci U S A (1977) 4.23
Non-coated membrane invaginations are involved in binding and internalization of cholera and tetanus toxins. Nature (1982) 4.22
Brefeldin A, a drug that blocks secretion, prevents the assembly of non-clathrin-coated buds on Golgi cisternae. Cell (1991) 4.17
Polarization of the Golgi apparatus and the microtubule-organizing center in cultured fibroblasts at the edge of an experimental wound. Proc Natl Acad Sci U S A (1982) 4.17
A coat subunit of Golgi-derived non-clathrin-coated vesicles with homology to the clathrin-coated vesicle coat protein beta-adaptin. Nature (1991) 4.09
A new type of coated vesicular carrier that appears not to contain clathrin: its possible role in protein transport within the Golgi stack. Cell (1986) 4.04
Epidermal growth factor: morphological demonstration of binding, internalization, and lysosomal association in human fibroblasts. Proc Natl Acad Sci U S A (1978) 4.03
Ezrin contains cytoskeleton and membrane binding domains accounting for its proposed role as a membrane-cytoskeletal linker. J Cell Biol (1993) 3.96
Dissection of a single round of vesicular transport: sequential intermediates for intercisternal movement in the Golgi stack. Cell (1989) 3.78
Uvomorulin: a nonintegral membrane protein of early mouse embryo. Proc Natl Acad Sci U S A (1983) 3.42
Basic fibroblast growth factor induces angiogenesis in vitro. Proc Natl Acad Sci U S A (1986) 3.42
Ligands internalized through coated or noncoated invaginations follow a common intracellular pathway. Proc Natl Acad Sci U S A (1987) 3.33
Bidirectional transport by distinct populations of COPI-coated vesicles. Cell (1997) 3.24
Viral membrane proteins acquire galactose in trans Golgi cisternae during intracellular transport. J Cell Biol (1982) 3.18
Binding of coatomer to Golgi membranes requires ADP-ribosylation factor. J Biol Chem (1993) 3.01
Characterization of an integral membrane glycoprotein associated with the microfilaments of pig intestinal microvilli. EMBO J (1983) 2.95
In vitro rapid organization of endothelial cells into capillary-like networks is promoted by collagen matrices. J Cell Biol (1983) 2.91
COPI- and COPII-coated vesicles bud directly from the endoplasmic reticulum in yeast. Cell (1995) 2.87
New perspectives on the microvasculature of the islets of Langerhans in the rat. Diabetes (1982) 2.87
Functional subdivision of islets of Langerhans and possible role of D cells. Lancet (1975) 2.83
Stepwise assembly of functionally active transport vesicles. Cell (1993) 2.80
Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors. Cell (1991) 2.78
Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene. Cell (1990) 2.77
Sar1 promotes vesicle budding from the endoplasmic reticulum but not Golgi compartments. J Cell Biol (1994) 2.75
Cell-mediated extracellular acidification and bone resorption: evidence for a low pH in resorbing lacunae and localization of a 100-kD lysosomal membrane protein at the osteoclast ruffled border. J Cell Biol (1985) 2.73
Inhibition of coated pit formation in Hep2 cells blocks the cytotoxicity of diphtheria toxin but not that of ricin toxin. J Cell Biol (1985) 2.71
Regulation of protein secretion through controlled aggregation in the endoplasmic reticulum. Science (2000) 2.70
Transforming growth factor beta stimulates collagen-matrix contraction by fibroblasts: implications for wound healing. Proc Natl Acad Sci U S A (1988) 2.69
Coated vesicle assembly in the Golgi requires only coatomer and ARF proteins from the cytosol. Nature (1993) 2.65
Direct identification of prohormone conversion site in insulin-secreting cells. Cell (1985) 2.64
Pancreatic beta-cell web: its possible role in insulin secretion. Science (1972) 2.63
Tumor-promoting phorbol esters induce angiogenesis in vitro. Cell (1985) 2.58
The aminopeptidase from hog intestinal brush border. Biochim Biophys Acta (1973) 2.57
Studies of the diabetogenic action of streptozotocin. Proc Soc Exp Biol Med (1967) 2.55
The essential role of glucagon in the pathogenesis of diabetes mellitus. Lancet (1975) 2.54
Insulin within islets is a physiologic glucagon release inhibitor. J Clin Invest (1984) 2.52
Hydrolysis of bound GTP by ARF protein triggers uncoating of Golgi-derived COP-coated vesicles. J Cell Biol (1993) 2.51
Ezrin is an effector of hepatocyte growth factor-mediated migration and morphogenesis in epithelial cells. J Cell Biol (1997) 2.51
Coupling of coat assembly and vesicle budding to packaging of putative cargo receptors. Cell (1999) 2.49
125I-insulin binding to cultured human lymphocytes. Initial localization and fate of hormone determined by quantitative electron microscopic autoradiography. J Clin Invest (1978) 2.47
Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro. Biochem Biophys Res Commun (1992) 2.47
Characterization of antigens recognized by monoclonal and polyclonal antibodies directed against uvomorulin. Proc Natl Acad Sci U S A (1985) 2.47
Morphogenic effects of ezrin require a phosphorylation-induced transition from oligomers to monomers at the plasma membrane. J Cell Biol (2000) 2.45
Heterogeneous distribution of filipin--cholesterol complexes across the cisternae of the Golgi apparatus. Proc Natl Acad Sci U S A (1981) 2.45
Dynamics of the COPII coat with GTP and stable analogues. Nat Cell Biol (2001) 2.44
Macro- and micro-domains in the endocrine pancreas. Diabetes (1982) 2.43
Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2. Proc Natl Acad Sci U S A (1997) 2.42
The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes. J Cell Biol (1990) 2.36
A view of acidic intracellular compartments. J Cell Biol (1988) 2.35
Proteolytic maturation of insulin is a post-Golgi event which occurs in acidifying clathrin-coated secretory vesicles. Cell (1987) 2.33
Regulation of fatty acid homeostasis in cells: novel role of leptin. Proc Natl Acad Sci U S A (1999) 2.33
The amino terminus of ADP-ribosylation factor (ARF) is a critical determinant of ARF activities and is a potent and specific inhibitor of protein transport. J Biol Chem (1992) 2.31
Embryogenesis of the murine endocrine pancreas; early expression of pancreatic polypeptide gene. Development (1991) 2.28
Mammalian Sec23p homologue is restricted to the endoplasmic reticulum transitional cytoplasm. Proc Natl Acad Sci U S A (1991) 2.27
Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells. Biochem Biophys Res Commun (1991) 2.25