Published in EMBO J on January 01, 1983
Ezrin contains cytoskeleton and membrane binding domains accounting for its proposed role as a membrane-cytoskeletal linker. J Cell Biol (1993) 3.96
Identification and characterization of podocalyxin--the major sialoprotein of the renal glomerular epithelial cell. J Cell Biol (1984) 3.91
Uvomorulin: a nonintegral membrane protein of early mouse embryo. Proc Natl Acad Sci U S A (1983) 3.42
Characterization of antigens recognized by monoclonal and polyclonal antibodies directed against uvomorulin. Proc Natl Acad Sci U S A (1985) 2.47
Antibodies to rat pancreas Golgi subfractions: identification of a 58-kD cis-Golgi protein. J Cell Biol (1987) 2.39
In vivo co-distribution of fibronectin and actin fibers in granulation tissue: immunofluorescence and electron microscope studies of the fibronexus at the myofibroblast surface. J Cell Biol (1984) 1.99
Can villin be used to identify malignant and undifferentiated normal digestive epithelial cells? Proc Natl Acad Sci U S A (1985) 1.83
Binding of brush border myosin I to phospholipid vesicles. J Cell Biol (1990) 1.81
A monoclonal anti-DNA antibody also binds to cell-surface protein(s). Proc Natl Acad Sci U S A (1984) 1.75
The 110-kD protein-calmodulin complex of the intestinal microvillus is an actin-activated MgATPase. J Cell Biol (1987) 1.71
Antibodies against lysosomal membranes reveal a 100,000-mol-wt protein that cross-reacts with purified H+,K+ ATPase from gastric mucosa. J Cell Biol (1984) 1.59
Assembly of the intestinal brush border: appearance and redistribution of microvillar core proteins in developing chick enterocytes. J Cell Biol (1987) 1.48
Targeting of Listeria monocytogenes ActA protein to the plasma membrane as a tool to dissect both actin-based cell morphogenesis and ActA function. EMBO J (1995) 1.46
Functional differences between L- and T-plastin isoforms. J Cell Biol (1994) 1.41
Reassociation of microvillar core proteins: making a microvillar core in vitro. J Cell Biol (1989) 1.40
Suppression of villin expression by antisense RNA impairs brush border assembly in polarized epithelial intestinal cells. EMBO J (1995) 1.36
A human villin cDNA clone to investigate the differentiation of intestinal and kidney cells in vivo and in culture. EMBO J (1986) 1.35
Changes in villin synthesis and subcellular distribution during intestinal differentiation of HT29-18 clones. J Cell Biol (1987) 1.33
Binding of a monoclonal anti-DNA autoantibody to identical protein(s) present at the surface of several human cell types involved in lupus pathogenesis. J Clin Invest (1985) 1.31
Actin-membrane interaction in fibroblasts: what proteins are involved in this association? J Cell Biol (1984) 1.29
Characterization of the collagen in the hexagonal lattice of Descemet's membrane: its relation to type VIII collagen. J Cell Biol (1990) 1.28
Partial deduced sequence of the 110-kD-calmodulin complex of the avian intestinal microvillus shows that this mechanoenzyme is a member of the myosin I family. J Cell Biol (1989) 1.23
Characterization of intestinal microvillar membrane disks: detergent-resistant membrane sheets enriched in associated brush border myosin I (110K-calmodulin). J Cell Biol (1989) 1.23
Biosynthesis of microvillar proteins. Biochem J (1984) 1.20
Brush border cytoskeleton and integration of cellular functions. J Cell Biol (1984) 1.19
Lipoprotein binding and endosomal itinerary of the low density lipoprotein receptor-related protein in rat liver. Proc Natl Acad Sci U S A (1989) 1.15
HT-29 cells are an in vitro model for the generation of cell polarity in epithelia during embryonic differentiation. Proc Natl Acad Sci U S A (1988) 1.11
A membrane cytoskeleton from Dictyostelium discoideum. II. Integral proteins mediate the binding of plasma membranes to F-actin affinity beads. J Cell Biol (1984) 1.08
Surface marker for hemopoietic and endothelial cell lineages in quail that is defined by a monoclonal antibody. Proc Natl Acad Sci U S A (1983) 1.07
Villin expression in the visceral endoderm and in the gut anlage during early mouse embryogenesis. EMBO J (1988) 1.05
Human systemic lupus erythematosus sera contain antibodies against cell-surface protein(s) that share(s) epitope(s) with DNA. Proc Natl Acad Sci U S A (1986) 1.05
Microvillus 110K-calmodulin: effects of nucleotides on isolated cytoskeletons and the interaction of the purified complex with F-actin. J Cell Biol (1985) 1.04
In vivo analysis of functional domains from villin and gelsolin. J Cell Biol (1992) 1.03
A neuronal surface glycoprotein associated with the cytoskeleton. J Cell Biol (1984) 0.96
Evidence for a polarity in the distribution of proteins from the cytoskeleton in Torpedo marmorata electrocytes. J Cell Biol (1986) 0.96
Mitosis in sand dollar embryos is inhibited by antibodies directed against the calcium transport enzyme of muscle. Proc Natl Acad Sci U S A (1986) 0.92
(Na+ + K+)-ATPase and plasma membrane polarity of intestinal epithelial cells: presence of a brush border antigen in the distal large intestine that is immunologically related to beta subunit. J Cell Biol (1989) 0.90
Membrane-associated actin in the rhabdomeral microvilli of crayfish photoreceptors. J Cell Biol (1984) 0.90
Altered cell-surface protein(s), crossreactive with DNA, on spleen cells of autoimmune lupic mice. Proc Natl Acad Sci U S A (1987) 0.89
Lumen formation and redistribution of inframembranous proteins during differentiation of ducts in the rat mammary gland. Proc Natl Acad Sci U S A (1984) 0.87
Presence of a protein immunologically related to lamin B in the postsynaptic membrane of Torpedo marmorata electrocyte. J Cell Biol (1989) 0.85
Microvillin: a 200-kilodalton protein in microvilli of rat mammary cells detected by a monoclonal antibody. Proc Natl Acad Sci U S A (1984) 0.85
Presence of antibodies against a cell-surface protein, cross-reactive with DNA, in systemic lupus erythematosus: a marker of the disease. Proc Natl Acad Sci U S A (1987) 0.84
Characterization and Localization of a Phenoloxidase in Mung Bean Hypocotyl Cell Walls. Plant Physiol (1994) 0.83
Inhibited gastrulation in mouse embryos overexpressing the leukemia inhibitory factor. Proc Natl Acad Sci U S A (1992) 0.83
Conditions leading to secretion of a normally periplasmic protein in Escherichia coli. J Bacteriol (1987) 0.82
Ca2+-ATPase of the sarcoplasmic reticulum shares a common domain with a membrane glycoprotein associated with the cytoskeleton of microvilli. Proc Natl Acad Sci U S A (1984) 0.75
Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis. J Biol Chem (1977) 72.51
"Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate--polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. Anal Biochem (1981) 71.15
The early stages of absorption of injected horseradish peroxidase in the proximal tubules of mouse kidney: ultrastructural cytochemistry by a new technique. J Histochem Cytochem (1966) 46.81
Phase separation of integral membrane proteins in Triton X-114 solution. J Biol Chem (1981) 26.33
Affinity purification of antibodies from diazotized paper blots of heterogeneous protein samples. J Biol Chem (1981) 9.11
Organization of an actin filament-membrane complex. Filament polarity and membrane attachment in the microvilli of intestinal epithelial cells. J Cell Biol (1975) 8.97
A technique for ultracryotomy of cell suspensions and tissues. J Cell Biol (1973) 8.64
Villin is a major protein of the microvillus cytoskeleton which binds both G and F actin in a calcium-dependent manner. Cell (1980) 4.83
Improved procedures for immunoferritin labeling of ultrathin frozen sections. J Cell Biol (1976) 4.58
Identification and organization of the components in the isolated microvillus cytoskeleton. J Cell Biol (1979) 4.12
Localization of actin and microfilament-associated proteins in the microvilli and terminal web of the intestinal brush border by immunofluorescence microscopy. J Cell Biol (1978) 3.98
Fimbrin, a new microfilament-associated protein present in microvilli and other cell surface structures. J Cell Biol (1980) 3.93
A study of positive staining of ultrathin frozen sections. J Ultrastruct Res (1978) 3.58
Brush border motility. Microvillar contraction in triton-treated brush borders isolated from intestinal epithelium. J Cell Biol (1976) 3.12
Purification of microvilli and an analysis of the protein components of the microfilament core bundle. Exp Cell Res (1978) 3.09
Immunocytochemical localization of alpha-actinin in intestinal epithelial cells. Proc Natl Acad Sci U S A (1979) 2.86
A sensitive immunoblotting method for measuring protein synthesis initiation factor levels in lysates of Escherichia coli. J Biol Chem (1981) 2.59
Biogenesis of intestinal plasma membrane: posttranslational route and cleavage of sucrase-isomaltase. Proc Natl Acad Sci U S A (1979) 2.45
Calmodulin-binding proteins of the microfilaments present in isolated brush borders and microvilli of intestinal epithelial cells. J Biol Chem (1980) 2.28
Brush-border calmodulin. A major component of the isolated microvillus core. J Cell Biol (1980) 2.23
On the preparation and some properties of closed membrane vesicles from hog duodenal and jejunal brush border. Biochim Biophys Acta (1973) 1.54
Topological studies on the hydrolases bound to the intestinal brush border membrane. I. Solubilization by papain and Triton X-100. Biochim Biophys Acta (1975) 1.51
Comparison of intestinal brush-border 95-Kdalton polypeptide and alpha-actinins. J Cell Biol (1980) 1.50
On the hydrophobic part of aminopeptidase and maltases which bind the enzyme to the intestinal brush border membrane. Biochim Biophys Acta (1976) 1.48
The brush-border intestinal aminopeptidase, a transmembrane protein as probed by macromolecular photolabelling. J Mol Biol (1976) 1.42
Immunolocalization of the 110,000 molecular weight cytoskeletal protein of intestinal microvilli. J Mol Biol (1981) 1.41
Villin associates with specific microfilamentous structures as seen by immunofluorescence microscopy on tissue sections and cells microinjected with villin. Exp Cell Res (1981) 1.17
The cytoskeleton of intestinal microvilli contains two polypeptides immunologically related to proteins of striated muscle. Cold Spring Harb Symp Quant Biol (1982) 0.97
Antibodies to the Golgi complex and the rough endoplasmic reticulum. J Cell Biol (1982) 7.02
Infectious entry pathway of influenza virus in a canine kidney cell line. J Cell Biol (1981) 6.46
Pathway of vesicular stomatitis virus entry leading to infection. J Mol Biol (1982) 5.21
A monoclonal antibody against a 135-K Golgi membrane protein. EMBO J (1982) 4.89
Apical membrane aminopeptidase appears at site of cell-cell contact in cultured kidney epithelial cells. Proc Natl Acad Sci U S A (1980) 4.63
Passage of viral membrane proteins through the Golgi complex. J Mol Biol (1981) 4.48
SSR alpha and associated calnexin are major calcium binding proteins of the endoplasmic reticulum membrane. J Biol Chem (1991) 4.48
Antibody-induced linkages of plasma membrane proteins to intracellular actomyosin-containing filaments in cultured fibroblasts. Proc Natl Acad Sci U S A (1977) 4.23
Polarization of the Golgi apparatus and the microtubule-organizing center in cultured fibroblasts at the edge of an experimental wound. Proc Natl Acad Sci U S A (1982) 4.17
Ezrin contains cytoskeleton and membrane binding domains accounting for its proposed role as a membrane-cytoskeletal linker. J Cell Biol (1993) 3.96
Uvomorulin: a nonintegral membrane protein of early mouse embryo. Proc Natl Acad Sci U S A (1983) 3.42
Viral membrane proteins acquire galactose in trans Golgi cisternae during intracellular transport. J Cell Biol (1982) 3.18
Cell-mediated extracellular acidification and bone resorption: evidence for a low pH in resorbing lacunae and localization of a 100-kD lysosomal membrane protein at the osteoclast ruffled border. J Cell Biol (1985) 2.73
Inhibition of coated pit formation in Hep2 cells blocks the cytotoxicity of diphtheria toxin but not that of ricin toxin. J Cell Biol (1985) 2.71
The aminopeptidase from hog intestinal brush border. Biochim Biophys Acta (1973) 2.57
Ezrin is an effector of hepatocyte growth factor-mediated migration and morphogenesis in epithelial cells. J Cell Biol (1997) 2.51
Characterization of antigens recognized by monoclonal and polyclonal antibodies directed against uvomorulin. Proc Natl Acad Sci U S A (1985) 2.47
Morphogenic effects of ezrin require a phosphorylation-induced transition from oligomers to monomers at the plasma membrane. J Cell Biol (2000) 2.45
Ezrin, a plasma membrane-microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway. Proc Natl Acad Sci U S A (1999) 2.21
Villin induces microvilli growth and actin redistribution in transfected fibroblasts. Cell (1989) 2.19
Regulatory sequences of the mouse villin gene that efficiently drive transgenic expression in immature and differentiated epithelial cells of small and large intestines. J Biol Chem (1999) 2.15
A novel tetanus neurotoxin-insensitive vesicle-associated membrane protein in SNARE complexes of the apical plasma membrane of epithelial cells. Mol Biol Cell (1998) 2.11
Transepithelial transport of a viral membrane glycoprotein implanted into the apical plasma membrane of Madin-Darby canine kidney cells. I. Morphological evidence. J Cell Biol (1983) 2.07
Growing an actin gel on spherical surfaces. Biophys J (2000) 2.06
Absorptive and mucus-secreting subclones isolated from a multipotent intestinal cell line (HT-29) provide new models for cell polarity and terminal differentiation. J Cell Biol (1987) 2.03
An actin-binding site containing a conserved motif of charged amino acid residues is essential for the morphogenic effect of villin. Cell (1992) 2.01
Raft association of SNAP receptors acting in apical trafficking in Madin-Darby canine kidney cells. Proc Natl Acad Sci U S A (1999) 1.95
The junction-associated protein, zonula occludens-1, localizes to the nucleus before the maturation and during the remodeling of cell-cell contacts. Proc Natl Acad Sci U S A (1996) 1.95
A monoclonal antibody to the heavy chain of clathrin. EMBO J (1983) 1.94
The secretion-stimulated 80K phosphoprotein of parietal cells is ezrin, and has properties of a membrane cytoskeletal linker in the induced apical microvilli. EMBO J (1991) 1.91
Membrane-actin microfilament connections: an increasing diversity of players related to band 4.1. Curr Opin Cell Biol (1994) 1.86
Ezrin has properties to self-associate at the plasma membrane. J Cell Sci (1994) 1.85
Assembled and unassembled pools of clathrin: a quantitative study using an enzyme immunoassay. J Cell Biol (1985) 1.84
Actin filaments facilitate two steps of endocytosis. J Cell Sci (1996) 1.83
Can villin be used to identify malignant and undifferentiated normal digestive epithelial cells? Proc Natl Acad Sci U S A (1985) 1.83
Role of tetanus neurotoxin insensitive vesicle-associated membrane protein (TI-VAMP) in vesicular transport mediating neurite outgrowth. J Cell Biol (2000) 1.82
A small rab GTPase is distributed in cytoplasmic vesicles in non polarized cells but colocalizes with the tight junction marker ZO-1 in polarized epithelial cells. J Cell Biol (1994) 1.80
Role of the glycocalyx in regulating access of microparticles to apical plasma membranes of intestinal epithelial cells: implications for microbial attachment and oral vaccine targeting. J Exp Med (1996) 1.75
A monoclonal anti-DNA antibody also binds to cell-surface protein(s). Proc Natl Acad Sci U S A (1984) 1.75
Sequence and overexpression of GPP130/GIMPc: evidence for saturable pH-sensitive targeting of a type II early Golgi membrane protein. Mol Biol Cell (1997) 1.72
In vivo, villin is required for Ca(2+)-dependent F-actin disruption in intestinal brush borders. J Cell Biol (1999) 1.69
LPP, an actin cytoskeleton protein related to zyxin, harbors a nuclear export signal and transcriptional activation capacity. Mol Biol Cell (2000) 1.62
Antibodies against lysosomal membranes reveal a 100,000-mol-wt protein that cross-reacts with purified H+,K+ ATPase from gastric mucosa. J Cell Biol (1984) 1.59
Characterization of molecules involved in protein translocation using a specific antibody. J Cell Biol (1982) 1.58
Lysosomes are associated with microtubules and not with intermediate filaments in cultured fibroblasts. Proc Natl Acad Sci U S A (1984) 1.56
Actin filaments and myosin I alpha cooperate with microtubules for the movement of lysosomes. Mol Biol Cell (2001) 1.56
On the preparation and some properties of closed membrane vesicles from hog duodenal and jejunal brush border. Biochim Biophys Acta (1973) 1.54
Clathrin-immunoreactive sites in the Golgi apparatus are concentrated at the trans pole in polypeptide hormone-secreting cells. Proc Natl Acad Sci U S A (1985) 1.54
Targeting of zyxin to sites of actin membrane interaction and to the nucleus. J Biol Chem (2001) 1.52
Characterization of the interaction between zyxin and members of the Ena/vasodilator-stimulated phosphoprotein family of proteins. J Biol Chem (2000) 1.51
Topological studies on the hydrolases bound to the intestinal brush border membrane. I. Solubilization by papain and Triton X-100. Biochim Biophys Acta (1975) 1.51
Sequence of human villin: a large duplicated domain homologous with other actin-severing proteins and a unique small carboxy-terminal domain related to villin specificity. J Cell Biol (1988) 1.49
Human fetal enterocytes in vitro: modulation of the phenotype by extracellular matrix. Proc Natl Acad Sci U S A (1996) 1.49
On the hydrophobic part of aminopeptidase and maltases which bind the enzyme to the intestinal brush border membrane. Biochim Biophys Acta (1976) 1.48
Na+-H+ exchanger 3 (NHE3) is present in lipid rafts in the rabbit ileal brush border: a role for rafts in trafficking and rapid stimulation of NHE3. J Physiol (2001) 1.47
Targeting of Listeria monocytogenes ActA protein to the plasma membrane as a tool to dissect both actin-based cell morphogenesis and ActA function. EMBO J (1995) 1.46
ActA and human zyxin harbour Arp2/3-independent actin-polymerization activity. Nat Cell Biol (2001) 1.46
Effect of cell shape change on the function and differentiation of rabbit mammary cells in culture. J Cell Biol (1983) 1.45
Transmembrane interactions and the mechanisms of transport of proteins across membranes. J Supramol Struct (1978) 1.44
The brush-border intestinal aminopeptidase, a transmembrane protein as probed by macromolecular photolabelling. J Mol Biol (1976) 1.42
Tight junction, a platform for trafficking and signaling protein complexes. J Cell Biol (2000) 1.41
Functional differences between L- and T-plastin isoforms. J Cell Biol (1994) 1.41
Immunolocalization of the 110,000 molecular weight cytoskeletal protein of intestinal microvilli. J Mol Biol (1981) 1.41
Use of immunocytochemical techniques in studying the biogenesis of cell surfaces in polarized epithelia. Methods Enzymol (1983) 1.39
Structural and topological homology between porcine intestinal and renal brush border aminopeptidase. Biochim Biophys Acta (1976) 1.37
Suppression of villin expression by antisense RNA impairs brush border assembly in polarized epithelial intestinal cells. EMBO J (1995) 1.36
GPI-anchored proteins associate to form microdomains during their intracellular transport in Caco-2 cells. J Cell Sci (1993) 1.36
Src-dependent ezrin phosphorylation in adhesion-mediated signaling. Mol Biol Cell (2005) 1.35
A human villin cDNA clone to investigate the differentiation of intestinal and kidney cells in vivo and in culture. EMBO J (1986) 1.35
Changes in villin synthesis and subcellular distribution during intestinal differentiation of HT29-18 clones. J Cell Biol (1987) 1.33
I-SceI-induced gene replacement at a natural locus in embryonic stem cells. Mol Cell Biol (1998) 1.32
A common exocytotic mechanism mediates axonal and dendritic outgrowth. J Neurosci (2001) 1.31
Binding of a monoclonal anti-DNA autoantibody to identical protein(s) present at the surface of several human cell types involved in lupus pathogenesis. J Clin Invest (1985) 1.31
Subcellular localization of tetanus neurotoxin-insensitive vesicle-associated membrane protein (VAMP)/VAMP7 in neuronal cells: evidence for a novel membrane compartment. J Neurosci (1999) 1.30
From the structure to the function of villin, an actin-binding protein of the brush border. Bioessays (1990) 1.29
Association of myosin I alpha with endosomes and lysosomes in mammalian cells. Mol Biol Cell (1999) 1.28
Partial deduced sequence of the 110-kD-calmodulin complex of the avian intestinal microvillus shows that this mechanoenzyme is a member of the myosin I family. J Cell Biol (1989) 1.23
Epoxide hydrolase is a marker for the smooth endoplasmic reticulum in rat liver. EMBO J (1985) 1.23
On porcine enterokinase. Further purification and some molecular properties. Biochim Biophys Acta (1973) 1.21
Developmental regulation of villin gene expression in the epithelial cell lineages of mouse digestive and urogenital tracts. Development (1992) 1.21
Are lysosomes a site of enveloped-virus penetration? Cold Spring Harb Symp Quant Biol (1982) 1.20
Villin-like actin-binding proteins are expressed ubiquitously in Arabidopsis. Plant Physiol (2000) 1.19
Human intestinal goblet cells in monolayer culture: characterization of a mucus-secreting subclone derived from the HT29 colon adenocarcinoma cell line. Gastroenterology (1988) 1.19
Brush border myosin-I truncated in the motor domain impairs the distribution and the function of endocytic compartments in an hepatoma cell line. Proc Natl Acad Sci U S A (1996) 1.19
Ezrin interacts with focal adhesion kinase and induces its activation independently of cell-matrix adhesion. J Biol Chem (2001) 1.17
Mutation of a cysteine in the first transmembrane segment of Na,K-ATPase alpha subunit confers ouabain resistance. EMBO J (1992) 1.17
Decay-accelerating factor (CD55) and membrane inhibitor of reactive lysis (CD59) are released within exosomes during In vitro maturation of reticulocytes. Blood (1998) 1.17
Polarized secretion of lysosomal enzymes: co-distribution of cation-independent mannose-6-phosphate receptors and lysosomal enzymes along the osteoclast exocytic pathway. J Cell Biol (1988) 1.16
Association of an aminoacyl-tRNA synthetase complex and of phenylalanyl-tRNA synthetase with the cytoskeletal framework fraction from mammalian cells. Exp Cell Res (1985) 1.15
Vimentin filaments in fibroblasts are a reservoir for SNAP23, a component of the membrane fusion machinery. Mol Biol Cell (2000) 1.15
Villin: a cytoskeletal protein and a differentiation marker expressed in some human adenocarcinomas. Virchows Arch B Cell Pathol Incl Mol Pathol (1987) 1.12
HT-29 cells are an in vitro model for the generation of cell polarity in epithelia during embryonic differentiation. Proc Natl Acad Sci U S A (1988) 1.11
Surface and cytoplasmic domains in polarized epithelial cells. Prog Clin Biol Res (1982) 1.11