Expression and intracellular transport of microvillus membrane hydrolases in human intestinal epithelial cells.

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Published in J Cell Biol on September 01, 1985

Authors

H P Hauri, E E Sterchi, D Bienz, J A Fransen, A Marxer

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Transport to cell surface of intestinal sucrase-isomaltase is blocked in the Golgi apparatus in a patient with congenital sucrase-isomaltase deficiency. Proc Natl Acad Sci U S A (1985) 1.00

The basophil activation marker defined by antibody 97A6 is identical to the ectonucleotide pyrophosphatase/phosphodiesterase 3. Blood (2001) 1.00

The nucleoporin CAN/Nup214 binds to both the cytoplasmic and the nucleoplasmic sides of the nuclear pore complex in overexpressing cells. Exp Cell Res (1997) 0.99

Sendai virus hemolysis: influence of lectins and analysis by immune fluorescence. Virology (1978) 0.99

The mouse Ptprr gene encodes two protein tyrosine phosphatases, PTP-SL and PTPBR7, that display distinct patterns of expression during neural development. Eur J Neurosci (1999) 0.98

Asynchronous transport to the cell surface of intestinal brush border hydrolases is not due to differential trimming of N-linked oligosaccharides. J Biol Chem (1989) 0.98

Heterologously overexpressed, affinity-purified human meprin alpha is functionally active and cleaves components of the basement membrane in vitro. FEBS Lett (2000) 0.97

Organ culture of human duodenum and jejunum. Biol Gastroenterol (Paris) (1976) 0.97

Naturally occurring mutations in intestinal sucrase-isomaltase provide evidence for the existence of an intracellular sorting signal in the isomaltase subunit. J Cell Biol (1991) 0.96

Biogenesis and intracellular transport of intestinal brush border membrane hydrolases. Use of antibody probes and tissue culture. Subcell Biochem (1988) 0.96

Differential regulation of metzincins in experimental chronic renal allograft rejection: potential markers and novel therapeutic targets. Kidney Int (2006) 0.96

Cloning of the PABA peptide hydrolase alpha subunit (PPH alpha) from human small intestine and its expression in COS-1 cells. FEBS Lett (1993) 0.96

On the origin of the FcRIII (CD16)-containing vesicle population in human neutrophil granulocytes. Eur J Cell Biol (1991) 0.95

Expression of the alpha subunit of PABA peptide hydrolase (EC 3.4.24.18) in MDCK cells. Synthesis and secretion of an enzymatically inactive homodimer. FEBS Lett (1993) 0.94

Structure, biosynthesis, and glycosylation of human small intestinal maltase-glucoamylase. J Biol Chem (1988) 0.94

Immunoblotting with monoclonal antibodies: importance of the blocking solution. Anal Biochem (1986) 0.94

Peptide hydrolases of the human small intestinal mucosa: distribution of activities between brush border membranes and cytosol. Clin Chim Acta (1980) 0.94

Antileukoprotease is associated with elastin fibers in the extracellular matrix of the human lung. An immunoelectron microscopic study. Am Rev Respir Dis (1989) 0.93

Biosynthesis and transport of plasma membrane glycoproteins in the rat intestinal epithelial cell: studies with sucrase-isomaltase. Ciba Found Symp (1983) 0.93

Congenital sucrase-isomaltase deficiency. Identification of a glutamine to proline substitution that leads to a transport block of sucrase-isomaltase in a pre-Golgi compartment. J Clin Invest (1996) 0.92